Pyrimidine derivatives exhibiting antitumor activity
    24.
    发明授权
    Pyrimidine derivatives exhibiting antitumor activity 失效
    具有抗肿瘤活性的嘧啶衍生物

    公开(公告)号:US06420367B1

    公开(公告)日:2002-07-16

    申请号:US09743721

    申请日:2001-01-16

    IPC分类号: A61K31505

    CPC分类号: C07D413/12

    摘要: A compound represented by the formula (I): wherein, for example, R1, R2, R3, and R4 are each independently hydrogen atom, alky, and the like, R5 and R6 are each independently hydrogen atom, alkyl, and the like, X is —O—, —S—, and the like, Y is 5-membered heteroaryl-diyl and the like, Z is optionally substituted aryl and the like, the prodrugs thereof, or their pharmaceutically acceptable salts, or their solvates.

    摘要翻译: 由式(I)表示的化合物:其中,例如,R 1,R 2,R 3和R 4各自独立地为氢原子,烷基等,R 5和R 6各自独立地为氢原子,烷基等, X是-O-,-S-等,Y是5元杂芳基 - 二基等,Z是任选取代的芳基等,其前药或其药学上可接受的盐或它们的溶剂合物。

    Vinyl chloride polymer resin composition
    25.
    发明授权
    Vinyl chloride polymer resin composition 失效
    氯乙烯聚合物树脂组合物

    公开(公告)号:US4699948A

    公开(公告)日:1987-10-13

    申请号:US801051

    申请日:1985-11-22

    摘要: Disclosed is a vinyl chloride polymer composition comprising:(i) 100 parts by weight of a vinyl chloride polymer containing at least 80 wt. % of vinyl chloride units, and(ii) 0.05 to 25 wt. parts of a three-stage polymer (II), which is obtained by polymerizing 10 to 30 wt. parts of at least one monomer (B), which is selected from acrylic acid esters, methacrylic acid esters, aromatic vinyl compounds, cyano-vinyl compounds and vinyl ester compounds so that the glass transition temperature of a polymer obtained by separately polymerizing the monomer (B) is 0.degree. to 60.degree. C., in the presence of 45 to 85 wt. parts of a methyl methacrylate polymer (A) containing at least 80 wt. % of methyl methacrylate units; and then polymerizing 5 to 25 wt. parts of a methyl methacrylate monomer or monomer mixture (C) containing at least 80 wt. % of methyl methacrylate in the presence of the obtained copolymer comprising the components (A) and (B) so that the total amount of the components (A), (B), and (C) is 100 wt. parts. The vinyl chloride polymer composition is advantageous in that the gelation speed is high, the parting property at the calendering step is good, adhesion to the vessel wall is not caused at the blending step before the processing, the processability is excellent, and the composition gives a molded articles having a good transparency and a good surface condition.

    摘要翻译: 公开了一种氯乙烯聚合物组合物,其包含:(i)100重量份的含有至少80重量% %的氯乙烯单元,和(ii)0.05〜25wt。 通过聚合10〜30重量份的三段聚合物(II) 选自丙烯酸酯,甲基丙烯酸酯,芳族乙烯基化合物,氰基乙烯基化合物和乙烯基酯化合物中的至少一种单体(B)的部分,使得通过单独聚合单体获得的聚合物的玻璃化转变温度( B)为0〜60℃,在45〜85wt。 部分甲基丙烯酸甲酯聚合物(A)含有至少80wt。 %的甲基丙烯酸甲酯单位; 然后聚合5〜25wt。 部分甲基丙烯酸甲酯单体或单体混合物(C)含有至少80wt。 在得到的包含组分(A)和(B)的共聚物存在下,使组分(A),(B)和(C)的总量为100重量% 部分。 氯乙烯聚合物组合物的优点在于凝胶化速度快,压延步骤的脱模性良好,在加工前的共混步骤中不会对容器壁产生附着力,加工性优异,组成给出 具有良好的透明性和良好的表面状态的成型品。

    Packaging machine
    26.
    发明授权
    Packaging machine 失效
    包装机

    公开(公告)号:US4590734A

    公开(公告)日:1986-05-27

    申请号:US616647

    申请日:1984-06-04

    申请人: Kazuo Ueda

    发明人: Kazuo Ueda

    IPC分类号: B65B3/02 B65B55/02

    CPC分类号: B65B3/025 B65B55/027

    摘要: A packaging machine comprising an endless conveyor, a mandrel wheel disposed above the starting end of the path of transport of the conveyor and having mandrels, a closed main chamber enclosing the conveyor and the mandrel wheel entirely, a series of devices arranged on the top wall of the main chamber from the rear to the front in succession for making tubular blanks into containers by closing one end of each blank to form the bottom of the container, filling contents into the bottomed blank and thereafter closing the other end of the blank to form the top of the container, the series of devices having portions operative on the blank and extending into the main chamber, and a closed subchamber disposed to the rear of the main chamber and communicating therewith, the subchamber having installed therein a blank sterilizer and a blank transfer assembly for transferring tubular blanks from a blank shaping-feeding unit to the blank sterilizer and for transferring sterilized tubular blanks from the sterilizer to the mandrel wheel. The device for filling contents into the bottomed blank includes a filling nozzle and a liquid conduit disposed therebelow which is rotatably mounted so as to be able to be positioned to receive contents passed through the filling nozzle.

    摘要翻译: 一种包装机,包括环形输送机,心轴轮设置在输送机输送路径的起始端上方,并具有心轴,封闭的主室,整个包围输送机和心轴轮;一系列装置,其布置在顶壁 的主室连续地从后到前,通过关闭每个坯料的一端以形成容器的底部,从而将管状坯料制成容器,将内容物填充到有底的坯料中,然后关闭坯料的另一端以形成 容器的顶部,具有在坯件上操作并延伸到主室中的部分的一系列装置以及设置在主室的后部并与之连通的封闭副室,其中安装有空白灭菌器和空白的子室 用于将管坯从坯料成形给料单元转移到空白灭菌器和用于转移灭菌的管状坯料的转移组件 从灭菌器到心轴轮。 用于将内容物填充到有底坯件中的装置包括填充喷嘴和布置在其下方的液体导管,其可旋转地安装以便能够定位成接收通过填充喷嘴的内容物。

    Method of coloring glass sheet by diffusion and reduction of silver ions
    27.
    发明授权
    Method of coloring glass sheet by diffusion and reduction of silver ions 失效
    通过扩散和还原银离子对玻璃板进行着色的方法

    公开(公告)号:US4397667A

    公开(公告)日:1983-08-09

    申请号:US328630

    申请日:1981-12-08

    IPC分类号: C03C21/00 C03C17/10

    CPC分类号: C03C21/008

    摘要: A method of coloring a glass sheet which must contain reducing ions such as tin ions diffused into a surface layer thereof. The reducing ions may originate in a molten metal bath used in producing the glass sheet by the float process. A coloring agent comprising a powder mixture of 1 part by weight of a substance expressed by Ag.sub.x W.sub.y O.sub.z, wherein x:y:z is 1-2:1:2-4, and 5 to 20 parts by weight of a transition metal oxide, e.g. Cr.sub.2 O.sub.3, is applied to the glass sheet surface, and the glass sheet is heated so as to cause silver ions to diffuse into the surface layer of the glass sheet and undergo reduction by the action of the precedingly diffused ions to produce color. Conveniently, use is made of a paste prepared by dispersing the powder mixture in an organic liquid vehicle. Owing to the stability of the silver-containing oxide Ag.sub.x W.sub.y O.sub.z, uniform coloring is achieved without encountering difficulty and without degrading the quality of the glass sheet.

    摘要翻译: 将含有还原离子如锡离子扩散到其表面层中的玻璃板着色的方法。 还原离子可以源自用于通过浮法生产玻璃板的熔融金属浴。 一种着色剂,其包含1重量份由Ag x W y O z表示的物质,其中x:y:z为1-2:1-2:2-4的粉末混合物和5至20重量份的过渡金属氧化物,例如, 将Cr 2 O 3施加到玻璃板表面,并且加热玻璃板以使银离子扩散到玻璃板的表面层中,并通过前述扩散离子的作用进行还原以产生颜色。 方便地,使用通过将粉末混合物分散在有机液体载体中制备的糊剂。 由于含银氧化物Ag x W y O z的稳定性,可以实现均匀的着色而不会困难,而且不降低玻璃板的质量。

    Device for measuring blood pressure
    28.
    发明授权
    Device for measuring blood pressure 失效
    用于测量血压的装置

    公开(公告)号:US4181122A

    公开(公告)日:1980-01-01

    申请号:US787638

    申请日:1977-04-14

    申请人: Kazuo Ueda

    发明人: Kazuo Ueda

    摘要: Device for use in measurement of blood pressure, according to the intermediate blood pressure measuring method of RIVA ROCCI, which detects negative signals of Korotkoff sound pulses comprised in asymmetrical alternating current signal waves coming from a ceramic microphone through a band pass filter and a half-wave rectifier, and indicates the presence of the Korotkoff sound after shaping the negative signals in a monostable multivibrator.

    摘要翻译: 用于测量血压的装置,根据RIVA ROCCI的中间血压测量方法,其检测包含在来自陶瓷麦克风的不对称交流信号波中的Korotkoff声脉冲的负信号通过带通滤波器和半通滤波器, 波形整流器,并且在单稳态多谐振荡器中对负信号进行整形后,指示Korotkoff声音的存在。

    Sphygmomanometer cuff
    30.
    发明授权
    Sphygmomanometer cuff 失效
    血压计袖口

    公开(公告)号:US4106499A

    公开(公告)日:1978-08-15

    申请号:US783524

    申请日:1977-04-01

    申请人: Kazuo Ueda

    发明人: Kazuo Ueda

    IPC分类号: A61B5/022 A61B5/02

    CPC分类号: A61B5/02233 Y10S128/20

    摘要: A sphygmomanometer cuff adapted to be easily applicable to any limb of a patient by himself. The cuff comprises an elongated flexible double layered fabric strap holding an inflatable pouch with tubes to be connected at the outside of the strap to a sphygmomanometer and to an air pump, and having a length sufficient to wrap by about one and a half to two turns round the patient's limb. A loop shaped rigid member is fitted at one longitudinal end of the strap, and received in the other longitudinal end thereof is a resiliently compressible rod like member. The rod like member can be forced through the loop shaped rigid member and prevents the strap from withdrawing from the loop shaped rigid member. A pair of female and male adhesive tapes are provided on the strap and are spaced apart by a distance permitting superimposing for fastening when the strap is wrapped round a patient's limb so as to stop the flow of blood through the arteries.

    摘要翻译: 血压计袖口适用于自己易于适用于患者的任何肢体。 袖带包括细长的柔性双层织物带,其保持具有管的外部带有管的可充气袋到血压计和空气泵,并且具有足够的长度以包裹大约一至半至两匝 围绕病人的肢体。 环形刚性构件装配在带的一个纵向端部,并且在其另一纵向端部中容纳有可弹性压缩的杆状构件。 杆状构件可以被迫通过环形刚性构件并防止带从环形刚性构件中退出。 一对阴阳性胶带设在带子上,并隔开一段距离,使得当带子缠绕在患者肢体周围时可重叠紧固,以便阻止血液通过动脉流动。