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    Method and apparatus for monitoring cardiac output of a patient in a home environment
    5.
    发明授权
    Method and apparatus for monitoring cardiac output of a patient in a home environment 有权
    用于在家庭环境中监测患者的心输出量的方法和装置

    公开(公告)号：US09326735B2

    公开(公告)日：2016-05-03

    申请号：US14399759

    申请日：2013-04-23

    申请人： KONINKLIJKE PHILIPS N.V.

    发明人： Jens Muhlsteff

    IPC分类号： A61B5/02 ,  A61B5/00 ,  A61B5/029 ,  A61B5/0205 ,  A61B5/026 ,  A61B5/0402 ,  A61B5/11 ,  A61B7/04 ,  A61B7/00 ,  A61B5/024 ,  A61B5/021

    CPC分类号： A61B5/7278 ,  A61B5/02007 ,  A61B5/0205 ,  A61B5/021 ,  A61B5/02416 ,  A61B5/0261 ,  A61B5/029 ,  A61B5/0402 ,  A61B5/1116 ,  A61B5/486 ,  A61B5/7225 ,  A61B5/7246 ,  A61B5/7285 ,  A61B5/742 ,  A61B5/7475 ,  A61B7/006 ,  A61B7/045 ,  A61B2505/07

    摘要： There is provided a method of determining a measure of the cardiac output, CO, of a patient, the method comprising obtaining measurements of one or more physiological characteristics of the patient, the physiological characteristics including at least the heart rate, HR, of the patient, the systolic blood pressure, S, of the patient and the diastolic blood pressure, D, of the patient; and processing the measurements to determine a measure of the cardiac output of the patient; wherein the measure of the cardiac output of the patient is derived using the relationship CO = K 1 ⁡ ( HR ⁢ S - D S + D ) , CO = K 2 ⁢ HR ⁡ ( S - D ) ⁢ ( PTT ) 2 , and ⁢ / ⁢ or ⁢ CO = K 2 ⁢ HR ⁡ ( S - D ) ⁢ ( PAT - PEP ) 2 where K1 and K2 are patient-specific calibration factors, PAT is the pulse arrival time, PEP is the pre-ejection period and PTT is the pulse transit time, the time taken for a pulse wave to travel between two points in the body of the patient.

    摘要翻译： 提供了一种确定患者的心输出量CO的测量方法，所述方法包括获得患者的一种或多种生理特征的测量值，所述生理特征至少包括患者的心率（HR） ，患者的收缩压S和患者的舒张压D; 以及处理所述测量以确定所述患者的心输出量的度量; 其中，使用关系式CO = K 1⁡（HRS-DS + D），CO = K 2 HR⁡（S-D）（PTT）2和 /或CO = K 2 HR⁡（S-D）（PAT-PEP）2其中K1和K2是患者特异性校准因子，PAT是脉冲到达时间，PEP是预喷射时期，PTT 是脉搏传播时间，脉搏波在患者体内两点之间行进的时间。

    Acoustic monitoring of a breast and sound databases for improved detection of breast cancer
    9.
    发明授权
    Acoustic monitoring of a breast and sound databases for improved detection of breast cancer 失效
    乳房和声音数据库的声学监测，以改善乳腺癌的检测

    公开(公告)号：US08100839B2

    公开(公告)日：2012-01-24

    申请号：US12609716

    申请日：2009-10-30

    申请人： Benjamin M. Galkin

    发明人： Benjamin M. Galkin

    IPC分类号： A61B7/00

    CPC分类号： A61B6/0485 ,  A61B5/02208 ,  A61B5/055 ,  A61B6/0414 ,  A61B6/502 ,  A61B7/045 ,  G06F19/00

    摘要： Provided are methods and devices that pertain to the acquisition of data related to breast vascularity associated with breast cancer, use of data, or both, that are associated with the generation of sounds, including Korotkoff sounds, within a breast. The present methods and devices overcome the inherent limitations associated with x-ray absorption (upon which mammography relies) by the breast tissue of younger women, and may also be used to augment traditional single-parameter (visual) analysis of a breast through the use of a new parameter—sound. Also disclosed are databases comprising breast sounds that may be used to provide a more complete assessment of a patient's breast, either alone or in combination with the traditional visual parameter.

    摘要翻译： 提供了与在乳房内产生声音（包括Korotkoff声音）相关的与乳腺癌相关的乳房血管相关数据，数据或两者的使用有关的数据的方法和装置。 本发明的方法和装置克服了由年轻女性的乳腺组织引起的x射线吸收（乳房X线照相所依赖）的固有限制，并且还可以用于通过使用来增加乳房的传统单参数（视觉）分析 的新参数声音。 还公开了包括乳房声音的数据库，其可用于单独地或与传统视觉参数组合来提供患者乳房的更完整的评估。

    Mammography systems and methods, including methods utilizing breast sound comparison
    10.
    发明授权
    Mammography systems and methods, including methods utilizing breast sound comparison 失效
    乳房X线摄影系统和方法，包括利用乳房声音比较的方法

    公开(公告)号：US07634049B2

    公开(公告)日：2009-12-15

    申请号：US12043009

    申请日：2008-03-05

    申请人： Benjamin M. Galkin

    发明人： Benjamin M. Galkin

    IPC分类号： A61B6/04

    CPC分类号： A61B6/0485 ,  A61B6/0414 ,  A61B6/502 ,  A61B7/045 ,  G06F19/00

    摘要： Provided are systems using compression devices for a mammography unit, and methods of using the same. The instant mammography units can comprise at least one x-ray transparent inflatable chamber. When fluid is introduced into the chamber, at least one surface of the chamber expands, and the breast and its vasculature are compressed. Fluid may also be released from the chamber, and as the chamber deflates, blood flow to the breast is restored, producing Korotkoff sounds. Sound data may be obtained with respect to both of a patient's breasts, and the sound data from a patient's first breast may be compared with the data obtained from the contralateral breast. The detected sounds, the comparison data, or both may assist a radiologist in identifying regions of interest on a mammogram, and to enhance a computer-assisted detection (CAD) process and a database of mammography images.

    摘要翻译： 提供了使用用于乳房X线照相术单元的压缩装置的系统及其使用方法。 即时乳房X线照相术单元可以包括至少一个x射线透明可充气室。 当流体进入腔室时，腔室的至少一个表面膨胀，并且乳房及其脉管系统被压缩。 流体也可以从腔室中释放出来，随着腔室的缩小，血液流向乳房被恢复，产生Korotkoff声音。 可以相对于患者的乳房获得声音数据，并且可以将来自患者的第一乳房的声音数据与从对侧乳房获得的数据进行比较。 检测到的声音，比较数据或两者可以帮助放射科医师识别乳房X线照片上的感兴趣区域，并且增强计算机辅助检测（CAD）过程和乳房X线照相图像的数据库。