公开(公告)号：US11480584B2

公开(公告)日：2022-10-25

申请号：US16777820

申请日：2020-01-30

Applicant: Life Technologies Holdings PTE Limited ,  Life Technologies Corporation

Inventor： Kuan Moon Boo ,  Wei Fuh Teo ,  Zeqi Tan ,  Soo Yong Lau ,  Ming Tiong Sia ,  Woon Liang Soh ,  Ching Yee Lam ,  Shan Hua Dong ,  Marc Haberstroh ,  Michael C. Pallas ,  Hardeep Sangha

IPC: G01N35/00 ,  B01L3/00 ,  B01L7/00 ,  G06K7/10 ,  G06K19/07 ,  G10L15/22 ,  G06V40/16

Abstract: A system for biological analysis includes a housing, a block assembly within the housing having a sample block and a baseplate, a heated cover and a cover carrier. The sample block receives a sample holder comprising an RFID tag. A first drive mechanism generates relative movement between the sample block and the baseplate along a first axis. A second drive mechanism generates relative movement between the heated cover and the cover carrier along a second axis that is different from the first axis. Based on a first command the first drive mechanism releasably engages the sample block and operates the second drive mechanism to releasably engage the heated cover with the cover carrier. The system also includes first and second RFID antennas that receive RFID data from the sample holder RFID tag that is read by at least one RFID reader.

公开(公告)号：US10471431B2

公开(公告)日：2019-11-12

申请号：US14613496

申请日：2015-02-04

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Chee Kiong Lim ,  Way Xuang Lee ,  Wuh Ken Loh ,  Chee Wee Ching ,  Chin Yong Koo ,  Siew Ying Koh ,  Tiong Han Toh ,  Kuan Moon Boo ,  Soo Yong Lau

IPC: B01L7/00 ,  C12Q1/6806

Abstract: In one aspect, a thermal cycler system including a sample block and a thermoelectric device is disclosed. In various embodiments, the sample block has a first surface configured to receive a plurality of reaction vessels and an opposing second surface. In various embodiments the thermoelectric device is operably coupled to the second surface of the sample block. In various embodiments a thermal control unit is provided. In various embodiments the thermal control unit includes a computer processing unit. In various embodiments the thermal control unit includes an electrical current source. In various embodiments the thermal control unit also includes an electrical interface portion configured to connect the thermoelectric device with the electrical current source by way of an electrical cable. In various embodiments the thermal control unit is oriented in a different plane than the sample block and thermoelectric cooler.

公开(公告)号：US09702823B2

公开(公告)日：2017-07-11

申请号：US14348878

申请日：2012-09-28

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Kevin Maher ,  Mingsong Chen ,  Jacob Freudenthal ,  Kuan Moon Boo ,  Soo Yong Lau ,  David Fortescue ,  Ming Shen ,  Woon Liang Terence Soh

IPC: G01N21/64

CPC classification number: G01N21/6486 ,  G01N21/6428 ,  G01N21/6452 ,  G01N2021/6471 ,  G01N2021/6478 ,  G01N2201/062

Abstract: An instrument for processing and/or measuring a biological process contains an excitation source, a sample holder, an optical sensor, an excitation optical system, and an emission optical system. The sample holder is configured to receive a plurality of biological samples. The optical sensor is configured to receive an emission from the biological samples. The excitation optical system is disposed along an excitation optical path and is configured to direct the electromagnetic radiation from the excitation source to the biological samples. The emission optical system is disposed along an emission optical path and is configured to direct electromagnetic emissions from the biological samples to the optical sensor. The instrument further contains a plurality of filter assemblies configured to be interchangeably located along at least one of the optical paths. The plurality of filter components includes a first filter assembly characterized by a first optical power and a first filter having a first filter function, the first filter function characterized by at least one of a first low-pass wavelength or a first high-pass wavelength. The second filter assembly is characterized by a second optical power and a second filter having a second filter function, the second filter function comprising at least one of a second low-pass wavelength that is different than the first low-pass wavelength or a second high-pass wavelength that is different than the first high-pass wavelength.

公开(公告)号：US20160228876A1

公开(公告)日：2016-08-11

申请号：US15017393

申请日：2016-02-05

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Yong Chu ,  Jeffrey Marks ,  Jacob Freudenthal ,  Mingsong Chen ,  Tiong Han Toh ,  Mauro Aguanno ,  Lik Seng Lau ,  Lian Seng Loh ,  Kok Siong Teo ,  Zeng Wei Chu ,  Xin Mathers ,  Michael Uy ,  Huei Yeo ,  Kuan Moon Boo ,  Way Xuang Lee ,  Chin Yong Koo ,  Wei Fuh Teo ,  Soo Yong Lau ,  Hon Siu Shin ,  Zeqi Tan ,  Thomas Wessel ,  Woo David

IPC: B01L7/00 ,  C12Q1/68 ,  G01N21/64

CPC classification number: B01L7/52 ,  B01L2200/145 ,  B01L2300/18 ,  B01L2300/1822 ,  C12Q1/6806 ,  G01N21/274 ,  G01N21/6452 ,  G01N21/6486 ,  G01N35/026 ,  G01N2021/6439 ,  G01N2035/00316 ,  G01N2035/00366 ,  G01N2201/061 ,  G01N2201/12

Abstract: A biological analysis system is provided. The system comprises a sample block assembly. The sample block assembly comprises a sample block configured to accommodate a sample holder, the sample holder configured to receive a plurality of samples. The system also comprises a control system configured to cycle the plurality of samples through a series of temperatures. The system further comprises an automated tray comprising a slide assembly, the tray configured to reversibly slide the sample block assembly from a closed to an open position to allow user access to the plurality of sample holders.

Abstract translation: 提供生物分析系统。 该系统包括样品块组件。 样品块组件包括被配置为容纳样品架的样品块，样品保持器被配置为接收多个样品。 该系统还包括配置成使多个样品循环通过一系列温度的控制系统。 所述系统还包括自动盘，其包括滑动组件，所述托盘被配置为可将所述样品块组件从关闭位置可逆地滑动至打开位置，以允许使用者接近所述多个样品保持器。