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Patent Agency Ranking
公开(公告)号：US20240309441A1
公开(公告)日：2024-09-19
申请号：US18583747
申请日：2024-02-21
Applicant: Life Technologies Corporation
Inventor： Mingsong Chen , Soo Yong Lau , Kuan Moon Boo , Mauro Aguanno , Huei Yeo , Tiong Han Toh , Wei Fuh Teo
CPC classification number: C12Q1/686 , B01L7/52 , G01N21/6428 , G01N21/6452 , G01N21/6456 , G01N21/6458 , G02B21/244 , B01L2200/10 , B01L2300/0654 , B01L2300/0829 , B01L2300/168 , B01L2300/18 , G01N2021/6463
Abstract: An instrument for biological analysis includes a base, an excitation source, an optical sensor, an excitation optical system, and an emission optical system. The base is configured to receive a sample holder comprising a plurality of biological samples. The optical sensor is configured to receive emissions from the biological samples in response to the excitation source. The instrument may additionally include a sensor lens enclosed by a lens case and a focusing mechanism including a gear that engages the lens case, the focusing mechanism being accessible outside the enclosure for adjusting a focus. The instrument may further include a sensor aperture dispose along an emission optical path and a blocking structure disposed to cooperate with the sensor aperture such that none of the reflected radiation from an illuminated surface near the sample holder is received by the optical sensor that does not also reflect off another surface of the instrument.
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公开(公告)号：US20160228876A1
公开(公告)日：2016-08-11
申请号：US15017393
申请日：2016-02-05
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Yong Chu , Jeffrey Marks , Jacob Freudenthal , Mingsong Chen , Tiong Han Toh , Mauro Aguanno , Lik Seng Lau , Lian Seng Loh , Kok Siong Teo , Zeng Wei Chu , Xin Mathers , Michael Uy , Huei Yeo , Kuan Moon Boo , Way Xuang Lee , Chin Yong Koo , Wei Fuh Teo , Soo Yong Lau , Hon Siu Shin , Zeqi Tan , Thomas Wessel , Woo David
CPC classification number: B01L7/52 , B01L2200/145 , B01L2300/18 , B01L2300/1822 , C12Q1/6806 , G01N21/274 , G01N21/6452 , G01N21/6486 , G01N35/026 , G01N2021/6439 , G01N2035/00316 , G01N2035/00366 , G01N2201/061 , G01N2201/12
Abstract: A biological analysis system is provided. The system comprises a sample block assembly. The sample block assembly comprises a sample block configured to accommodate a sample holder, the sample holder configured to receive a plurality of samples. The system also comprises a control system configured to cycle the plurality of samples through a series of temperatures. The system further comprises an automated tray comprising a slide assembly, the tray configured to reversibly slide the sample block assembly from a closed to an open position to allow user access to the plurality of sample holders.
Abstract translation: 提供生物分析系统。 该系统包括样品块组件。 样品块组件包括被配置为容纳样品架的样品块，样品保持器被配置为接收多个样品。 该系统还包括配置成使多个样品循环通过一系列温度的控制系统。 所述系统还包括自动盘，其包括滑动组件，所述托盘被配置为可将所述样品块组件从关闭位置可逆地滑动至打开位置，以允许使用者接近所述多个样品保持器。
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公开(公告)号：US11920191B2
公开(公告)日：2024-03-05
申请号：US17151657
申请日：2021-01-18
Applicant: Life TECHNOLOGIES CORPORATION
Inventor： Mingsong Chen , Kuan Moon Boo , Tiong Han Toh , Mauro Aguanno , Soo Yong Lau , Huei Yeo , Wei Fuh Teo
CPC classification number: C12Q1/686 , B01L7/52 , G01N21/6428 , G01N21/6452 , G01N21/6456 , G01N21/6458 , G02B21/244 , B01L2200/10 , B01L2300/0654 , B01L2300/0829 , B01L2300/168 , B01L2300/18 , G01N2021/6463
Abstract: An instrument for biological analysis includes a base, an excitation source, an optical sensor, an excitation optical system, and an emission optical system. The base is configured to receive a sample holder comprising a plurality of biological samples. The optical sensor is configured to receive emissions from the biological samples in response to the excitation source. The instrument may additionally include a sensor lens enclosed by a lens case and a focusing mechanism including a gear that engages the lens case, the focusing mechanism being accessible outside the enclosure for adjusting a focus. The may instrument further include a sensor aperture dispose along an emission optical path and a blocking structure disposed to cooperate with the sensor aperture such that none of the reflected radiation from an illuminated surface near the sample holder is received by the optical sensor that does not also reflect off another surface of the instrument.
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公开(公告)号：US20150217292A1
公开(公告)日：2015-08-06
申请号：US14617831
申请日：2015-02-09
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Hwee Tian Ng , Huei Yeo , Wei Hsien Choo
CPC classification number: B01L7/52 , B01L9/523 , B01L2200/0689 , B01L2300/041 , B01L2300/0654 , B01L2300/0663 , B01L2300/0829 , B01L2300/1822 , B01L2300/1833 , B01L2300/1894 , C12Q1/686
Abstract: The present invention relates to a thermal cycler for the carrying out of chemical or biological reactions, such as PCR or other nucleic acid amplification reactions, that is segmented with a plurality of reaction vessel receiving elements. The reaction vessel receiving elements are thermally isolated from each other and provide an airtight seal to prevent liquids or moisture from penetrating below the reaction vessel receiving elements. The reaction vessel receiving elements have several recesses arranged in a pattern to receive the reaction vessels of a single standard microtiter plate and the segmented thermal cycler has a system for independently heating and cooling each of the reaction vessel receiving elements.
Abstract translation: 本发明涉及用于进行用多个反应容器接收元件分段的化学或生物反应（例如PCR或其他核酸扩增反应）的热循环仪。 反应容器接收元件彼此热隔离并提供气密密封，以防止液体或湿气渗透到反应容器接收元件下方。 反应容器接收元件具有以图案方式排列以容纳单个标准微量滴定板的反应容器的多个凹槽，并且分段热循环器具有用于独立地加热和冷却每个反应容器接收元件的系统。
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公开(公告)号：US10286398B2
公开(公告)日：2019-05-14
申请号：US14617831
申请日：2015-02-09
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Hwee Tian Ng , Huei Yeo , Wei Hsien Choo
Abstract: The present invention relates to a thermal cycler for the carrying out of chemical or biological reactions, such as PCR or other nucleic acid amplification reactions, that is segmented with a plurality of reaction vessel receiving elements. The reaction vessel receiving elements are thermally isolated from each other and provide an airtight seal to prevent liquids or moisture from penetrating below the reaction vessel receiving elements. The reaction vessel receiving elements have several recesses arranged in a pattern to receive the reaction vessels of a single standard microtiter plate and the segmented thermal cycler has a system for independently heating and cooling each of the reaction vessel receiving elements.
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