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公开(公告)号：USD975873S1
公开(公告)日：2023-01-17
申请号：US29741481
申请日：2020-07-13
设计人： Marie Murakami , Kyle Bulloch , Neil Olson , Joshua Mead , Ross Winnick , Wei Fuh Teo , Michael Thacker
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公开(公告)号：US20230031117A1
公开(公告)日：2023-02-02
申请号：US17966364
申请日：2022-10-14
发明人： Kuan Moon Boo , Wei Fuh Teo , Zeqi Tan , Soo Yong Lau , Ming Tiong Sia , Woon Liang Soh , Ching Yee Lam , Shan Hua Dong , Marc Haberstroh , Michael C. Pallas , Hardeep Sangha
摘要： A system for biological analysis includes a housing, a block assembly within the housing having a sample block and a baseplate, a heated cover and a cover carrier. The sample block receives a sample holder comprising an RFID tag. A first drive mechanism generates relative movement between the sample block and the baseplate along a first axis. A second drive mechanism generates relative movement between the heated cover and the cover carrier along a second axis that is different from the first axis. Based on a first command the first drive mechanism releasably engages the sample block and operates the second drive mechanism to releasably engage the heated cover with the cover carrier. The system also includes first and second RFID antennas that receive RFID data from the sample holder RFID tag that is read by at least one RFID reader.
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公开(公告)号：US11529598B2
公开(公告)日：2022-12-20
申请号：US16424629
申请日：2019-05-29
发明人： Joshua Mead , Scott Rickes , Sean Zimmerman , Alessandra Barbosa , Mio Ling , Woon Liang Soh , Kevin Mullen , Christopher Brau , Jordan Cobia , Harmon Jr Cosme Sicat , Kok Shyong Chong , Han Wei , Wei Fuh Teo , Syed Muhammad Baber Ali
IPC分类号： C12M1/02 , B01F33/84 , C12M1/00 , C12M1/06 , C12M1/36 , B01F35/513 , G08B21/18 , B01F101/44
摘要： The present set of embodiments relate to a system, method, and apparatus controlling a cell culture media mixing system. The control system includes an integrated control unit capable of controlling a broad ranges of peripheral devices commonly used in bioproduction through a graphical user interface displayed on a touch sensitive screen. The bioproduction system is designed to be highly customizable through process modification and recipe creation by user with little or no knowledge of programming and is capable of controlling a wide variety of devices using a single unit. The bioproduction system allows for auto-detection, auto-calibration, and automatic of device related processes into a bioproduction workflow.
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公开(公告)号：US11480584B2
公开(公告)日：2022-10-25
申请号：US16777820
申请日：2020-01-30
发明人： Kuan Moon Boo , Wei Fuh Teo , Zeqi Tan , Soo Yong Lau , Ming Tiong Sia , Woon Liang Soh , Ching Yee Lam , Shan Hua Dong , Marc Haberstroh , Michael C. Pallas , Hardeep Sangha
摘要： A system for biological analysis includes a housing, a block assembly within the housing having a sample block and a baseplate, a heated cover and a cover carrier. The sample block receives a sample holder comprising an RFID tag. A first drive mechanism generates relative movement between the sample block and the baseplate along a first axis. A second drive mechanism generates relative movement between the heated cover and the cover carrier along a second axis that is different from the first axis. Based on a first command the first drive mechanism releasably engages the sample block and operates the second drive mechanism to releasably engage the heated cover with the cover carrier. The system also includes first and second RFID antennas that receive RFID data from the sample holder RFID tag that is read by at least one RFID reader.
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公开(公告)号：US20230123126A1
公开(公告)日：2023-04-20
申请号：US18053089
申请日：2022-11-07
发明人： Joshua Mead , Scott Rickes , Sean Zimmerman , Alessandra Barbosa , Kevin Mullen , Christopher Brau , Jordan Cobia , Mio Ling , Woon Liang Soh , Harmon Cosme Sicat, JR. , Kok Shyong Chong , Han Wei , Wei Fuh Teo , Syed Muhammad Baber Ali
IPC分类号： B01F33/84 , C12M1/00 , C12M1/06 , C12M1/36 , B01F35/513
摘要： A bioproduction mixer control system includes a mixing compartment having a biological fluid and a mixing element; a sensor in communication with the mixing compartment, the sensor configured to detect an environmental condition within the mixing compartment; and an integrated control unit. The integrated control unit includes a memory for storing the environmental condition, sensor information relating to the sensor, and process workflow information; a user interface comprising a display depicting a bioproduction workspace, wherein the bioproduction workspace comprises a process workflow title and a plurality of bioprocess modules; and a central processing unit in electronic communication with the sensor, memory and user interface.
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公开(公告)号：US20230221343A1
公开(公告)日：2023-07-13
申请号：US17923900
申请日：2021-05-08
发明人： Kuan Moon Boo , Wei Fuh Teo , Zeqi Tan , Ming Tiong Sia , Ching Yee Lam , Shan Hua Dong , Woon Liang Soh , Soo Yong Lau
CPC分类号： G01N35/04 , B01L3/502715 , B01L7/52 , G01N35/00732 , B01L2200/16 , B01L2200/026 , B01L2300/022 , B01L2300/042 , B01L2300/0663 , G01N2035/00366 , G01N2035/00376 , G01N2035/00831
摘要： A biological analysis system for performing a performing an assay or experiment includes one or more of a carrier, base, or tray. The carrier, base, or tray is/are configured to interchangeably receive (1) a first block and a corresponding first cover placed over the first block or (2) a second block and a corresponding second cover placed over the second block; The system also includes a computer readable memory comprising instructions for detecting when the second cover is placed over the first block and/or for detecting when the first cover is placed over the second block based on lack of electrical continuity along an electrical path comprising one of the blocks and one of the covers.
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公开(公告)号：US11583862B2
公开(公告)日：2023-02-21
申请号：US15266943
申请日：2016-09-15
发明人： Kuan Moon Boo , Wei Fuh Teo , Wuh Ken Loh , Zeqi Tan , Siew Yin Lee
摘要： A thermal block assembly for use in a biological analysis system includes a sample block, a heating and cooling element, a heat sink including a surface, the surface including a plurality of projections for engaging the heating and cooling element to hold the heating and cooling element on the heat sink. A thermal block assembly for use in a biological analysis system includes a heating and cooling element, a sample block including a lower surface configured to be thermally coupled to the heating and cooling element, one or more temperature sensors configured to extend through the one or more slots of the lower surface of the sample block, and one or more thermal pads between the one or more temperature sensors and heating and cooling element.
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公开(公告)号：US20240309441A1
公开(公告)日：2024-09-19
申请号：US18583747
申请日：2024-02-21
发明人： Mingsong Chen , Soo Yong Lau , Kuan Moon Boo , Mauro Aguanno , Huei Yeo , Tiong Han Toh , Wei Fuh Teo
CPC分类号： C12Q1/686 , B01L7/52 , G01N21/6428 , G01N21/6452 , G01N21/6456 , G01N21/6458 , G02B21/244 , B01L2200/10 , B01L2300/0654 , B01L2300/0829 , B01L2300/168 , B01L2300/18 , G01N2021/6463
摘要： An instrument for biological analysis includes a base, an excitation source, an optical sensor, an excitation optical system, and an emission optical system. The base is configured to receive a sample holder comprising a plurality of biological samples. The optical sensor is configured to receive emissions from the biological samples in response to the excitation source. The instrument may additionally include a sensor lens enclosed by a lens case and a focusing mechanism including a gear that engages the lens case, the focusing mechanism being accessible outside the enclosure for adjusting a focus. The instrument may further include a sensor aperture dispose along an emission optical path and a blocking structure disposed to cooperate with the sensor aperture such that none of the reflected radiation from an illuminated surface near the sample holder is received by the optical sensor that does not also reflect off another surface of the instrument.
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公开(公告)号：US20170072398A1
公开(公告)日：2017-03-16
申请号：US15266943
申请日：2016-09-15
发明人： Kuan Moon Boo , Wei Fuh Teo , Wuh Ken Loh , Zeqi Tan , Siew Yin Lee
CPC分类号： B01L7/52 , B01L2200/025 , B01L2200/04 , B01L2200/147 , B01L2300/0829 , B01L2300/1822 , F25B21/04 , F25B2321/0251
摘要： A thermal block assembly for use in a biological analysis system includes a sample block, a heating and cooling element, a heat sink including a surface, the surface including a plurality of projections for engaging the heating and cooling element to hold the heating and cooling element on the heat sink. A thermal block assembly for use in a biological analysis system includes a heating and cooling element, a sample block including a lower surface configured to be thermally coupled to the heating and cooling element, one or more temperature sensors configured to extend through the one or more slots of the lower surface of the sample block, and one or more thermal pads between the one or more temperature sensors and heating and cooling element.
摘要翻译： 用于生物分析系统的热块组件包括样品块，加热和冷却元件，包括表面的散热器，所述表面包括多个突起，用于接合加热和冷却元件以保持加热和冷却元件 在散热片上 用于生物分析系统的热块组件包括加热和冷却元件，样品块，其包括配置成热耦合到加热和冷却元件的下表面，配置成延伸穿过所述一个或多个 样品块的下表面的槽，以及一个或多个温度传感器和加热和冷却元件之间的一个或多个热垫。
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公开(公告)号：US20160228876A1
公开(公告)日：2016-08-11
申请号：US15017393
申请日：2016-02-05
发明人： Yong Chu , Jeffrey Marks , Jacob Freudenthal , Mingsong Chen , Tiong Han Toh , Mauro Aguanno , Lik Seng Lau , Lian Seng Loh , Kok Siong Teo , Zeng Wei Chu , Xin Mathers , Michael Uy , Huei Yeo , Kuan Moon Boo , Way Xuang Lee , Chin Yong Koo , Wei Fuh Teo , Soo Yong Lau , Hon Siu Shin , Zeqi Tan , Thomas Wessel , Woo David
CPC分类号： B01L7/52 , B01L2200/145 , B01L2300/18 , B01L2300/1822 , C12Q1/6806 , G01N21/274 , G01N21/6452 , G01N21/6486 , G01N35/026 , G01N2021/6439 , G01N2035/00316 , G01N2035/00366 , G01N2201/061 , G01N2201/12
摘要： A biological analysis system is provided. The system comprises a sample block assembly. The sample block assembly comprises a sample block configured to accommodate a sample holder, the sample holder configured to receive a plurality of samples. The system also comprises a control system configured to cycle the plurality of samples through a series of temperatures. The system further comprises an automated tray comprising a slide assembly, the tray configured to reversibly slide the sample block assembly from a closed to an open position to allow user access to the plurality of sample holders.
摘要翻译： 提供生物分析系统。 该系统包括样品块组件。 样品块组件包括被配置为容纳样品架的样品块，样品保持器被配置为接收多个样品。 该系统还包括配置成使多个样品循环通过一系列温度的控制系统。 所述系统还包括自动盘，其包括滑动组件，所述托盘被配置为可将所述样品块组件从关闭位置可逆地滑动至打开位置，以允许使用者接近所述多个样品保持器。
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