公开(公告)号：US20240278002A1

公开(公告)日：2024-08-22

申请号：US18637653

申请日：2024-04-17

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/90 ,  A61M60/13 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/806 ,  A61M60/81 ,  A61M60/818

CPC classification number: A61M60/90 ,  A61M60/13 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/806 ,  A61M60/81 ,  A61M60/818 ,  A61M2205/04 ,  A61M2205/103 ,  A61M2205/3606 ,  A61M2205/50 ,  A61M2207/10

Abstract: Apparatus and methods are described including inserting a drive-cable end of a drive cable, which includes a plurality of coiled wires, and a hollow-shaft end of a hollow shaft, which hollow-shaft end is shaped to define multiple shaft pores, into opposing ends of a coupling tube, which is shaped to define multiple coupling-tube pores. While the drive-cable end and hollow-shaft end are inside the coupling tube, a molten material is flowed between the coiled wires at the drive-cable end via the coupling-tube pores, and into the hollow-shaft end via the coupling-tube pores and shaft pores, such that, upon solidifying, the material bonds the drive cable to the shaft. Other applications are also described.

公开(公告)号：US20240278000A1

公开(公告)日：2024-08-22

申请号：US18639098

申请日：2024-04-18

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/825 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/531 ,  A61M60/585 ,  A61M60/808 ,  A61M60/81 ,  A61M60/829

CPC classification number: A61M60/825 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/531 ,  A61M60/585 ,  A61M60/808 ,  A61M60/81 ,  A61M60/829 ,  A61M2205/04 ,  A61M2205/103 ,  A61M2205/502 ,  A61M2210/125

Abstract: Apparatus and methods are described including a blood pump that includes an axial shaft configured for insertion into, and rotation within, a subject's body, and an impeller coupled to the axial shaft such that, as the axial shaft rotates, the impeller pumps blood of the subject. A frame surrounds the impeller and includes a distal conical portion. A bearing adjacent to the axial shaft is configured to stabilize the axial shaft while the axial shaft rotates. A bearing housing houses the bearing. The bearing housing is disposed at least partly within the distal conical portion of the frame such that at least 50% of the length of the bearing housing is disposed within the frame. Other applications are also described.

公开(公告)号：US20240277991A1

公开(公告)日：2024-08-22

申请号：US18640260

申请日：2024-04-19

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/178 ,  A61M60/237 ,  A61M60/419 ,  A61M60/531 ,  A61M60/818 ,  A61M60/829

CPC classification number: A61M60/178 ,  A61M60/237 ,  A61M60/419 ,  A61M60/531 ,  A61M60/818 ,  A61M60/829

Abstract: Apparatus and methods are described including a blood pump that includes an axial shaft configured for insertion into, and rotation within, a left ventricle of a subject, and an impeller coupled to the axial shaft such that, as the axial shaft rotates, the impeller pumps blood from the left ventricle. A frame surrounds the impeller and a tip portion is coupled to a distal end of the frame. The tip portion includes a distal curved portion, which, when deployed within the left ventricle, lies in a plane, and a proximal curved portion, which, when deployed within the left ventricle, does not lie in the plane and is curved such that, following the insertion of the axial shaft into the left ventricle via an aorta of the subject, a distal end of the proximal curved portion points toward an apex of the left ventricle. Other applications are also described.

公开(公告)号：US20240261561A1

公开(公告)日：2024-08-08

申请号：US18632569

申请日：2024-04-11

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/178 ,  A61M60/226 ,  A61M60/419 ,  A61M60/531 ,  A61M60/538 ,  A61M60/818 ,  A61M60/829 ,  A61M60/865

CPC classification number: A61M60/178 ,  A61M60/226 ,  A61M60/419 ,  A61M60/531 ,  A61M60/538 ,  A61M60/818 ,  A61M60/829 ,  A61M60/865

Abstract: Apparatus and methods are described including a left-ventricular assist device that includes a pump-outlet tube shaped to define one or more blood-outlet openings and including a narrower section, and a wider section, which is proximal to and wider than the narrower section, and which is shaped to define at least a portion of each of the blood-outlet openings such that a normal vector to the portion has a distally-facing component. The pump-outlet tube is inserted, through the subject's aorta, into the subject's left ventricle such that the pump-outlet tube traverses an aortic valve of the subject with the blood-outlet openings being disposed within the aorta. An impeller is disposed within the narrower section of the pump-outlet tube and is configured to pump blood of the subject, through the blood-outlet openings, from the left ventricle into the aorta. Other applications are also described.

公开(公告)号：US20170333673A1

公开(公告)日：2017-11-23

申请号：US15656685

申请日：2017-07-21

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Ehud SCHWAMMENTHAL ,  Daniel GLOZMAN

IPC: A61M25/00 ,  A61M1/12 ,  A61M1/10

CPC classification number: A61M25/0023 ,  A61M1/101 ,  A61M1/1024 ,  A61M1/1034 ,  A61M1/122 ,  A61M1/125 ,  A61M25/0041

Abstract: Apparatus and methods are described including inserting a catheter into a subject's body via a vein of the subject's groin. The catheter is advanced distally such that a distal end of the catheter is disposed inside the subject's renal vein. Respective stabilizing portions of the catheter stabilize the catheter by being in contact with inner walls of, respectively, an iliac vein of the subject, and a vena cava of the subject. Subsequently, a medical device is deployed inside the renal vein by retracting the distal end of the catheter, such that the distal end of the catheter is in a retracted state, in which the respective stabilizing portions of the catheter still stabilize the catheter by being in contact with the inner walls of, respectively, the subject's iliac vein and the subject's vena cava. Other applications are also described.

公开(公告)号：US20250010060A1

公开(公告)日：2025-01-09

申请号：US18889744

申请日：2024-09-19

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/90 ,  A61L29/02 ,  A61M39/10 ,  A61M60/13 ,  A61M60/17 ,  A61M60/174 ,  A61M60/178 ,  A61M60/216 ,  A61M60/226 ,  A61M60/237 ,  A61M60/242 ,  A61M60/295 ,  A61M60/408 ,  A61M60/414 ,  A61M60/419 ,  A61M60/497 ,  A61M60/508 ,  A61M60/531 ,  A61M60/538 ,  A61M60/554 ,  A61M60/585 ,  A61M60/806 ,  A61M60/808 ,  A61M60/81 ,  A61M60/816 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/859 ,  A61M60/865

Abstract: Apparatus and methods are described including a blood pump that includes a pump-outlet tube shaped to define one or more blood-outlet openings and configured for insertion into a heart of a subject. An impeller is disposed within a distal portion of the pump-outlet tube and is configured to pump blood of the subject proximally through the pump-outlet tube, such that the blood exits the pump-outlet tube through the blood-outlet openings. A delivery tube extends, from outside a body of the subject, through the pump-outlet tube to the distal portion. A drive cable passes through the delivery tube and is configured to rotate the impeller. A proximal portion of the pump-outlet tube includes multiple strips adhered to the delivery tube. Other embodiments are also described.

公开(公告)号：US20250000376A1

公开(公告)日：2025-01-02

申请号：US18882984

申请日：2024-09-12

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61B5/0215 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/554 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/00 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/18 ,  F04D29/24

Abstract: Apparatus and methods are described including a left ventricular assist device that includes an axial flow impeller configured to be disposed within a subject's left ventricle and to pump blood axially from the subject's left ventricle to the subject's aorta. A frame is disposed around the impeller, the frame being shaped such that, in a non-radially-constrained configuration of the frame, the frame defines a central cylindrical portion, and a distal conical portion. The frame is at least partially covered with one or more tube portions, the tube portions defining one or more blood-inlet openings that are configured to allow blood to flow from the subject's left ventricle into the tube portions, wherein at least some of the one or more blood-inlet openings are at least partially disposed over the distal conical portion of the frame. Other applications are also described.

公开(公告)号：US20240359000A1

公开(公告)日：2024-10-31

申请号：US18639087

申请日：2024-04-18

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/818 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/808 ,  A61M60/81 ,  A61M60/829

CPC classification number: A61M60/818 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/808 ,  A61M60/81 ,  A61M60/829 ,  A61M2205/0211 ,  A61M2205/0222 ,  A61M2205/04 ,  A61M2205/103 ,  A61M2205/502

Abstract: Apparatus and methods are described including a blood pump that includes an axial shaft configured for insertion into, and rotation within, a body of a subject. An impeller is coupled to the axial shaft such that, as the axial shaft rotates, the impeller pumps blood of the subject. A thrust bearing includes a proximally-facing ceramic surface disposed distally from the axial shaft so as to inhibit distal movement of the axial shaft beyond the thrust bearing, and a distally-facing ceramic cover that covers a distal end of the axial shaft, such that the ceramic cover contacts the ceramic surface as the axial shaft rotates. Other applications are also described.

公开(公告)号：US20240342464A1

公开(公告)日：2024-10-17

申请号：US18632545

申请日：2024-04-11

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/90 ,  A61M60/13 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/508 ,  A61M60/585 ,  A61M60/808 ,  A61M60/81

CPC classification number: A61M60/90 ,  A61M60/13 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/508 ,  A61M60/585 ,  A61M60/808 ,  A61M60/81 ,  A61M2205/103 ,  A61M2205/502 ,  A61M2210/125

Abstract: Apparatus and methods are described including a left-ventricular assist device that includes a pump-outlet tube shaped to define one or more blood-outlet openings and configured for insertion, through an aorta of a subject, into a left ventricle of a heart of the subject such that the pump-outlet tube traverses an aortic valve of the subject with the blood-outlet openings being disposed within the aorta. A blood pump is disposed at least partly within a distal portion of the pump-outlet tube and is configured to pump blood of the subject proximally through the pump-outlet tube. A proximal end of the pump-outlet tube is folded inwardly so as to define one or more surfaces configured to direct the blood through the blood-outlet openings by virtue of being oblique with respect to a longitudinal axis of the pump-outlet tube. Other applications are also described.

公开(公告)号：US20240299733A1

公开(公告)日：2024-09-12

申请号：US18654336

申请日：2024-05-03

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/90 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/829 ,  A61M60/865

CPC classification number: A61M60/90 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/829 ,  A61M60/865 ,  A61M2205/0266 ,  A61M2205/04 ,  A61M2205/103 ,  A61M2205/3303 ,  A61M2205/3327 ,  A61M2205/3331 ,  A61M2205/3365 ,  A61M2205/502 ,  A61M2207/10 ,  A61M2230/30

Abstract: Apparatus and methods are described including an axial shaft and an impeller configured for rotation within a subject's body. A coupling element includes a first portion, which is disposed around the axial shaft, is shaped to define one or more slits that facilitate a radial expansion of the first portion such that the first portion is placeable around the axial shaft, and is shape-set to have an inner diameter that is smaller than a diameter of the axial shaft such that, following placement of the first portion around the axial shaft, the first portion becomes radially contracted around, and thus locked in place with respect to, the axial shaft. A second portion of the coupling element is coupled to a bushing of the impeller. Other applications are also described.