公开(公告)号：US08764116B2

公开(公告)日：2014-07-01

申请号：US12793721

申请日：2010-06-04

申请人： Reinhard Weber ,  Thomas Braun ,  Walter Richter ,  John Harding

发明人： Reinhard Weber ,  Thomas Braun ,  Walter Richter ,  John Harding

IPC分类号： A47C9/00 ,  A47C16/02

CPC分类号： A47C3/029 ,  A47C3/04 ,  A47C9/002

摘要： An item of seating furniture contains a seat providing a seat surface, a generally circular foot panel positioning the item of seating furniture on a floor, and a central part, which connects the seat to the foot panel and of which a vertical center axis runs centrally through the foot panel. The foot panel is of at least partially convex configuration and that side of the foot panel which is directed toward the floor is configured, at least in part, as a non-slip surface. This creates an ergonomic item of seating furniture which stands in a stable state.

摘要翻译： 座椅家具的一个项目包括一个提供座位表面的座位，一个大致圆形的脚踏板将座椅家具放置在地板上，中心部分将座椅连接到脚踏板上，其中心轴线垂直于中心轴 通过脚踏板。 脚踏板具有至少部分凸起的构造，并且指向地板的脚板的侧面被至少部分地构造为防滑表面。 这产生了稳定状态的座椅家具的符合人体工程学的项目。

公开(公告)号：US07976042B2

公开(公告)日：2011-07-12

申请号：US11841280

申请日：2007-08-20

申请人： Bradley E. Watson ,  Charles J. Chuba ,  Ben Yang ,  John Harding ,  Christopher J. Kuntze ,  Trevor Thompson

发明人： Bradley E. Watson ,  Charles J. Chuba ,  Ben Yang ,  John Harding ,  Christopher J. Kuntze ,  Trevor Thompson

IPC分类号： B60R3/02

CPC分类号： B60R3/02

摘要： A step assembly includes an upper housing adapted to be fixedly secured to the motor vehicle. A step is movable relative to the upper housing between a stowed position and a deployed position. A single arm is pivotal with respect to the upper housing and pivotal with respect to the step in order to form a three-bar linkage for moving the step between the stowed and deployed positions.

摘要翻译： 台阶组件包括适于固定地固定在机动车辆上的上壳体。 台阶可相对于上壳体在收起位置和展开位置之间移动。 单臂相对于上壳体枢转并且相对于台阶枢转，以形成用于在收起位置和展开位置之间移动台阶的三杆连杆。

公开(公告)号：US07504206B2

公开(公告)日：2009-03-17

申请号：US11217562

申请日：2005-09-01

申请人： Deborah Haines ,  Gordon Allan ,  John Ellis ,  Brian Meehan ,  Edward Clark ,  Lori Hassard ,  John Harding ,  Catherine Elisabeth Charreyre ,  Gilles Emile Chappuis ,  Francis McNeilly ,  Li Wang ,  Lorne A. Babiuk ,  Andrew A. Potter ,  Philip Willson

发明人： Deborah Haines ,  Gordon Allan ,  John Ellis ,  Brian Meehan ,  Edward Clark ,  Lori Hassard ,  John Harding ,  Catherine Elisabeth Charreyre ,  Gilles Emile Chappuis ,  Francis McNeilly ,  Li Wang ,  Lorne A. Babiuk ,  Andrew A. Potter ,  Philip Willson

IPC分类号： C12Q1/70 ,  A61K39/12

CPC分类号： C07K14/005 ,  A61K38/00 ,  A61K39/00 ,  A61K39/12 ,  A61K48/00 ,  A61K2039/51 ,  A61K2039/53 ,  A61K2039/552 ,  A61K2039/70 ,  C12N7/00 ,  C12N15/86 ,  C12N2750/10022 ,  C12N2750/10034 ,  C12N2750/10043 ,  C12Q1/701

摘要： The cloning of a novel PCVII viral genome is described as is expression of proteins derived from the PCVII genome. These proteins can be used in vaccine compositions for the prevention and treatment of PCVII infections, as well as in diagnostic methods for determining the presence of PCVII infections in a vertebrate subject. Polynucleotides derived from the viral genome can be used as diagnostic primers and probes.

摘要翻译： 新型PCVII病毒基因组的克隆描述为源自PCVII基因组的蛋白质的表达。 这些蛋白质可用于预防和治疗PCVII感染的疫苗组合物中，以及用于确定脊椎动物受试者中PCVII感染存在的诊断方法。 衍生自病毒基因组的多核苷酸可用作诊断引物和探针。

公开(公告)号：US20090008894A1

公开(公告)日：2009-01-08

申请号：US11666722

申请日：2005-10-31

申请人： Christopher J. Kuntze ,  Brad E. Watson ,  Dan Glovak ,  John Harding ,  Randy Bolt

发明人： Christopher J. Kuntze ,  Brad E. Watson ,  Dan Glovak ,  John Harding ,  Randy Bolt

IPC分类号： B60R3/02

CPC分类号： B60R3/002 ,  B60R3/02

摘要： A step assembly is provided for a bumper of a motor vehicle. The step assembly includes a mounting bracket fixedly secured to the bumper. A step is operatively coupled to the mounting bracket and is movable between a retracted position disposed adjacent the bumper and a deployed position extending away from the bumper. A pivot arm is pivotally interconnected between the mounting bracket and the step. A spring is secured between the mounting bracket and the pivot arm for biasing the pivot arm. The spring creates a tensile force. A lock arm is pivotally interconnected between the mounting bracket and the step. The lock arm defines a lock surface engaging the pivot arm while the tensile force of the spring locks the step in order to retain the step in one of the retracted and deployed positions.

摘要翻译： 提供了用于机动车辆的保险杠的步进组件。 台阶组件包括固定地固定在保险杠上的安装支架。 一个步骤可操作地联接到安装支架，并且可以在靠近保险杠设置的缩回位置和远离保险杠的展开位置之间移动。 枢转臂在安装支架和台阶之间枢转地互连。 弹簧被固定在安装支架和枢转臂之间，用于偏压枢转臂。 弹簧产生张力。 锁定臂在安装支架和台阶之间枢转地互连。 锁定臂限定与枢转臂接合的锁定表面，同时弹簧的张力锁定该台阶以便将该台阶保持在缩回和展开位置之一中。

公开(公告)号：US07192594B2

公开(公告)日：2007-03-20

申请号：US10653849

申请日：2003-09-02

申请人： Deborah Haines ,  Gordon Allan ,  John Ellis ,  Brian Meehan ,  Edward Clark ,  Lori Hassard ,  John Harding ,  Catherine Elisabeth Charreyre ,  Gilles Emile Chappuis ,  Francis McNeilly ,  Li Wang ,  Lorne A. Babiuk ,  Andrew A. Potter ,  Philip Willson

发明人： Deborah Haines ,  Gordon Allan ,  John Ellis ,  Brian Meehan ,  Edward Clark ,  Lori Hassard ,  John Harding ,  Catherine Elisabeth Charreyre ,  Gilles Emile Chappuis ,  Francis McNeilly ,  Li Wang ,  Lorne A. Babiuk ,  Andrew A. Potter ,  Philip Willson

IPC分类号： A61K39/12

CPC分类号： C07K14/005 ,  A61K38/00 ,  A61K39/00 ,  A61K39/12 ,  A61K48/00 ,  A61K2039/51 ,  A61K2039/53 ,  A61K2039/552 ,  A61K2039/70 ,  C12N7/00 ,  C12N15/86 ,  C12N2750/10022 ,  C12N2750/10034 ,  C12N2750/10043 ,  C12Q1/701

摘要： The cloning of a novel PCVII viral genome is described as is expression of proteins derived from the PCVII genome. These proteins can be used in vaccine compositions for the prevention and treatment of PCVII infections, as well as in diagnostic methods for determining the presence of PCVII infections in a vertebrate subject. Polynucleotides derived from the viral genome can be used as diagnostic primers and probes.

摘要翻译： 新型PCVII病毒基因组的克隆描述为源自PCVII基因组的蛋白质的表达。 这些蛋白质可用于预防和治疗PCVII感染的疫苗组合物中，以及用于确定脊椎动物受试者中PCVII感染存在的诊断方法。 衍生自病毒基因组的多核苷酸可用作诊断引物和探针。

公开(公告)号：US20050058653A1

公开(公告)日：2005-03-17

申请号：US10780318

申请日：2004-02-17

申请人： John Ellis ,  Gordon Allan ,  Brian Meehan ,  Edward Clark ,  Deborah Haines ,  Lori Hassard ,  John Harding ,  Catherine Charreyre ,  Gilles Chappuis ,  George Krakowka ,  Jean-Christophe Audonnet ,  Francis McNeilly

发明人： John Ellis ,  Gordon Allan ,  Brian Meehan ,  Edward Clark ,  Deborah Haines ,  Lori Hassard ,  John Harding ,  Catherine Charreyre ,  Gilles Chappuis ,  George Krakowka ,  Jean-Christophe Audonnet ,  Francis McNeilly

IPC分类号： A61K38/00 ,  A61K39/00 ,  A61K39/12 ,  A61K48/00 ,  C07K14/01 ,  C12N7/00

CPC分类号： C07K14/005 ,  A61K38/00 ,  A61K39/00 ,  A61K39/12 ,  A61K48/00 ,  A61K2039/51 ,  A61K2039/5252 ,  A61K2039/5256 ,  A61K2039/53 ,  A61K2039/552 ,  A61K2039/55566 ,  C12N7/00 ,  C12N2710/10343 ,  C12N2710/16743 ,  C12N2710/24043 ,  C12N2750/10022 ,  C12N2750/10034

摘要： Porcine circovirus-2 (PCV-2) is a recently identified agent wherein the potential spectrum of PCV-2-associated disease has been expanded by evidence of vertical and sexual transmission and associated reproductive failure in swine populations. PCV-2 was isolated from a litter of aborted piglets from a farm experiencing late term abortions and stillbirths. Severe, diffuse myocarditis was present in one piglet associated with extensive immunohistochemical staining for PCV-2 antigen. Variable amounts of PCV-2 antigen were also present in liver, lung and kidney of multiple fetuses. Inoculation of female pigs with a composition including an immunogen from PCV-2 or an epitope of interest from such an immunogen or with a vector expressing such an immunogen or epitope of interest prior to breeding, such as within the first five weeks of life, or prior to the perinatal period, or repeatedly over a lifetime, or during pregnancy, such as between the 6th and 8th and/or the 10th and 13th weeks of gestation, can lower viral titer, prevent myocarditis, abortion and intrauterine infection associated with porcine circovirus-2. In addition, innoculation of male and/or female pigs with the aforementioned compositions can be carried out to prevent transmission of PCV-2 from male to female (or vice versa) during mating. Thus, the invention involves methods and compositions for preventing myocarditis, abortion and intrauterine infection associated with porcine circovirus-2.

摘要翻译： 猪圆环病毒-2（PCV-2）是最近确定的药物，其中PCV-2相关疾病的潜在谱已经通过垂直和性传播的证据以及猪群体相关的生殖失败而扩大。 从经历了晚期堕胎和死胎的农场的排卵仔猪中分离出PCV-2。 在与PCV-2抗原的广泛免疫组织化学染色相关的一只仔猪中存在严重的弥漫性心肌炎。 不同量的PCV-2抗原也存在于多个胎儿的肝，肺和肾中。 包括来自PCV-2的免疫原的组合物或来自这种免疫原的感兴趣的表位的组合物的雌性猪或在繁殖之前（例如在生命的前五周内）表达这种免疫原或感兴趣的表位的载体，或 在围产期，或一生以上，或怀孕期间，例如6〜8和/或10〜13周的妊娠期间，可以降低病毒滴度 ，预防与猪圆环病毒-2相关的心肌炎，流产和子宫内感染。 此外，可以进行具有上述组成的雄性和/或雌性猪的接种，以防止在交配期间PCV-2从雄性到雌性（或反之亦然）的传播。 因此，本发明涉及用于预防与猪圆环病毒-2相关的心肌炎，流产和子宫内感染的方法和组合物。

公开(公告)号：US06660272B2

公开(公告)日：2003-12-09

申请号：US09884514

申请日：2001-06-19

申请人： Gordon Allan ,  Brian Meehan ,  Edward Clark ,  John Ellis ,  Deborah Haines ,  Lori Hassard ,  John Harding ,  Catherine Elisabeth Charreyre ,  Gilles Emile Chappuis ,  Francis McNeilly

发明人： Gordon Allan ,  Brian Meehan ,  Edward Clark ,  John Ellis ,  Deborah Haines ,  Lori Hassard ,  John Harding ,  Catherine Elisabeth Charreyre ,  Gilles Emile Chappuis ,  Francis McNeilly

IPC分类号： A61K3912

CPC分类号： C07K14/005 ,  A61K38/00 ,  A61K39/00 ,  A61K39/12 ,  A61K48/00 ,  A61K2039/51 ,  A61K2039/5252 ,  A61K2039/552 ,  A61K2039/55566 ,  C12N2710/10343 ,  C12N2710/16043 ,  C12N2710/24043 ,  C12N2750/10021 ,  C12N2750/10022 ,  C12N2750/10034 ,  C12N2750/10043 ,  C12N2750/10063 ,  C12N2750/10064

摘要： The invention relates to new porcine circovirus strains isolated from pulmonary or ganglionic samples obtained from farms affected by the post-weaning multisystemic wasting syndrome (PMWS). It relates to purified preparations of these strains, conventional attenuated or inactivated vaccines, recombinant live vaccines, plasmid vaccines and subunit vaccines, as well as reagents and diagnostic methods. It also relates to the DNA fragments which can be used for the production of subunits in an in vitro expression vector or as sequences to be integrated into a virus or plasmid type in vivo expression vector.

公开(公告)号：US20170024449A1

公开(公告)日：2017-01-26

申请号：US15289883

申请日：2016-10-10

申请人： Jonathan K. Wesley, SR. ,  Erik Cooley ,  Nathan Daniels ,  John Harding ,  Andrew Horlacher ,  Ryan McAlister ,  Ryan Sealy ,  Brian Taylor

发明人： Jonathan K. Wesley, SR. ,  Erik Cooley ,  Nathan Daniels ,  John Harding ,  Andrew Horlacher ,  Ryan McAlister ,  Ryan Sealy ,  Brian Taylor

IPC分类号： G06F17/30 ,  G06F9/445 ,  H04L29/08

摘要： Systems and methods for dynamically integrating disparate computer-aided dispatch (CAD) systems are disclosed. The systems and methods provide bi-directional interoperability between disparate CAD systems and maintain stateful ongoing interactions between interconnected CAD systems. Information objects in one CAD system are associated and bound to related objects in other CAD systems through a centralized information hub that transforms data items intelligently to facilitate communication and interaction between the CAD systems connected to the hub. The described systems and methods maintain complete and current perspectives of all relevant information for each CAD system connected to the information hub, thereby eliminating the need for point-to-point intelligence maintained by the CAD systems about the other interconnected CAD systems. As information updates are passed from CAD systems to the information hub and back out to other CAD systems, the information hub transforms and evaluates the information updates ensuring that only necessary information updates are forwarded.

摘要翻译： 公开了用于动态集成不同计算机辅助调度（CAD）系统的系统和方法。 系统和方法提供了不同的CAD系统之间的双向互操作性，并保持了互连的CAD系统之间的有状态的持续交互。 一个CAD系统中的信息对象通过集中式信息中心与其他CAD系统中的相关对象相关联并将其绑定到智能地转换数据项，以促进连接到集线器的CAD系统之间的通信和交互。 所描述的系统和方法对于连接到信息中心的每个CAD系统保持对所有相关信息的完整和当前的观点，从而消除对CAD系统对其他互联CAD系统所保持的点对点智能的需求。 随着信息更新从CAD系统传递到信息中心并返回到其他CAD系统，信息中心将转换和评估信息更新，确保仅转发必要的信息更新。

公开(公告)号：US09465839B2

公开(公告)日：2016-10-11

申请号：US14473896

申请日：2014-08-29

申请人： Jonathan Wesley ,  Erik Cooley ,  Nathan Daniels ,  John Harding ,  Andrew Horlacher ,  Ryan McAlister ,  Ryan Sealy ,  Brian Taylor

发明人： Jonathan Wesley ,  Erik Cooley ,  Nathan Daniels ,  John Harding ,  Andrew Horlacher ,  Ryan McAlister ,  Ryan Sealy ,  Brian Taylor

IPC分类号： G06F15/16 ,  G06F17/30 ,  G06F15/173

CPC分类号： G06F17/30569 ,  G06F8/65 ,  G06F15/173 ,  G06F17/30424 ,  H04L67/34

摘要： Systems and methods for dynamically integrating disparate computer-aided dispatch (CAD) systems are disclosed. The systems and methods provide bi-directional interoperability between disparate CAD systems and maintain stateful ongoing interactions between interconnected CAD systems. Information objects in one CAD system are associated and bound to related objects in other CAD systems through a centralized information hub that transforms data items intelligently to facilitate communication and interaction between the CAD systems connected to the hub. The described systems and methods maintain complete and current perspectives of all relevant information for each CAD system connected to the information hub, thereby eliminating the need for point-to-point intelligence maintained by the CAD systems about the other interconnected CAD systems. As information updates are passed from CAD systems to the information hub and back out to other CAD systems, the information hub transforms and evaluates the information updates ensuring that only necessary information updates are forwarded.

摘要翻译： 公开了用于动态集成不同计算机辅助调度（CAD）系统的系统和方法。 系统和方法提供了不同的CAD系统之间的双向互操作性，并保持了互连的CAD系统之间的有状态的持续交互。 一个CAD系统中的信息对象通过集中式信息中心与其他CAD系统中的相关对象相关联并将其绑定到智能地转换数据项，以促进连接到集线器的CAD系统之间的通信和交互。 所描述的系统和方法对于连接到信息中心的每个CAD系统保持对所有相关信息的完整和当前的观点，从而消除对CAD系统对其他互联CAD系统所保持的点对点智能的需求。 随着信息更新从CAD系统传递到信息中心并返回到其他CAD系统，信息中心将转换和评估信息更新，确保仅转发必要的信息更新。

公开(公告)号：US09434362B2

公开(公告)日：2016-09-06

申请号：US12748833

申请日：2010-03-29

申请人： John Harding ,  Erik Kauppi

发明人： John Harding ,  Erik Kauppi

IPC分类号： B60T8/64 ,  B60T8/17 ,  B60T1/10 ,  B60W10/08 ,  B60W10/184 ,  B60W30/18 ,  B60L7/26 ,  B60T7/00

CPC分类号： B60T8/1706 ,  B60L7/26 ,  B60L2200/12 ,  B60T1/10 ,  B60T2270/604 ,  B60W10/08 ,  B60W10/184 ,  B60W30/18127 ,  B60W2540/12 ,  B60Y2200/12

摘要： A braking system for an electric vehicle has a first wheel having a first friction brake and an electric motor and a second having a second friction brake. A first user-actuated brake lever is coupled to the first friction brake. The first brake lever has a first sensor indicating actuation of the first brake lever. A second user-actuated brake lever is coupled to the second friction brake. The second brake lever has a second sensor indicating actuation of the second brake lever. An electronic control unit electronically coupled to the first and second sensors and the electric motor commands the electric motor to operate as a generator when at least one of the brake levers is actuated.

摘要翻译： 一种用于电动车辆的制动系统具有具有第一摩擦制动器和电动机的第一轮和具有第二摩擦制动器的第二轮。 第一用户致动的制动杆联接到第一摩擦制动器。 第一制动杆具有指示第一制动杆的致动的第一传感器。 第二用户致动的制动杆联接到第二摩擦制动器。 第二制动杆具有指示第二制动杆的致动的第二传感器。 电动联接到第一和第二传感器的电子控制单元和电动机命令电动机在至少一个制动杆被致动时作为发电机操作。