专利检索 ap:("Mark S. Zeiner" OR "Jason L. Harris" OR "Michael J. Stokes" OR "Matthew D. Holcomb" OR "Mark S. Ortiz" OR "Eugene L. Timperman" OR "Alex P. Kondor") AND inv:"Mark S. Zeiner" 第 3 页

21.

发明申请
Method For Deploying Fasteners For Use In a Gastric Volume Reduction Procedure 失效
标题翻译：用于部分紧固件的方法用于胃减容程序

公开(公告)号：US20110082472A1

公开(公告)日：2011-04-07

申请号：US12573907

申请日：2009-10-06

申请人： Jason L. Harris , Matthew D. Holcomb , Mark S. Zeiner , Michael J. Stokes

发明人： Jason L. Harris , Matthew D. Holcomb , Mark S. Zeiner , Michael J. Stokes

IPC分类号： A61B17/10

CPC分类号： A61B17/0401 , A61B17/0467 , A61B17/0469 , A61B17/0482 , A61B17/3498 , A61B90/92 , A61B90/94 , A61B2017/00477 , A61B2017/00526 , A61B2017/0409 , A61B2017/0417 , A61B2017/0464 , A61B2017/0474 , A61B2017/0475 , A61B2017/0477 , A61B2017/0496 , A61B2017/06052 , A61B2017/2916 , A61B2017/2917 , A61B2017/292 , A61B2017/2923 , A61B2017/2926

摘要： A method for deploying fasteners including the steps of providing a device having a handle and at least one actuator. The handle is connected to an elongated hollow housing having distal and proximal ends. The device has a first cartridge containing at least one fastener releasably connectable to the handle and an elongated pusher movable through the hollow housing from the distal to the proximal end for deploying the fastener from the distal end. The method includes increasing the stiffness of the pusher at a distal end thereof and advancing the pusher through the elongated housing to deploy the fasteners.

摘要翻译： 一种用于部署紧固件的方法，包括以下步骤：提供具有手柄和至少一个致动器的装置。手柄连接到具有远端和近端的细长的中空壳体。该装置具有第一盒，该盒包含至少一个可释放地连接到手柄的紧固件，以及可从远端到近端可穿过中空壳体的细长推动器，用于从远端展开紧固件。该方法包括增加推动器在其远端处的刚度，并且推动推动器穿过细长壳体以展开紧固件。

22.

发明申请
Method for Applying A Surgical Staple 审中-公开
标题翻译：应用手术钉的方法

公开(公告)号：US20100191255A1

公开(公告)日：2010-07-29

申请号：US12609336

申请日：2009-10-30

申请人： Lawrence Crainich , Drew Pickering , Jason L. Harris , Michael J. Stokes , Mark S. Zeiner , Matthew D. Holcomb , Darrel M. Powell

发明人： Lawrence Crainich , Drew Pickering , Jason L. Harris , Michael J. Stokes , Mark S. Zeiner , Matthew D. Holcomb , Darrel M. Powell

IPC分类号： A61B17/10

CPC分类号： A61B17/0644 , A61B17/0682 , A61B2017/2925 , A61B2017/2946

摘要： A method of deploying a surgical fastener including the step of introducing the fastener into a body of a patient while the fastener is in a first shape having a first loop with a back span and an original size and shape. The method involves moving the end segments of the fastener in a first manner away from each other while maintaining the fastener in a closed loop. The method also involves moving the end segments of the fastener in a second manner away from each other to open the loop. The method further involves forming the fastener into a second loop having a width greater than the width of the first loop.

摘要翻译： 一种部署手术紧固件的方法，包括以下步骤：当紧固件处于具有后跨距和原始尺寸和形状的第一环的第一形状时将紧固件引入患者体内。该方法包括将紧固件的端部段以彼此相离的方式移动，同时将紧固件保持在闭环状态。该方法还涉及将紧固件的端部段以彼此远离的第二方式移动以打开环路。该方法还包括将紧固件形成为具有大于第一回路宽度的宽度的第二回路。

23.

发明授权
Surgical stapler fastening device with movable anvil 有权
标题翻译：具有活动砧座的手术吻合器固定装置

公开(公告)号：US08439244B2

公开(公告)日：2013-05-14

申请号：US13015977

申请日：2011-01-28

申请人： Matthew D. Holcomb , Jason L. Harris , Michael J. Stokes , Mark S. Zeiner , Jonathan B. O'Keefe , Keith D. Boudreau , Jeffrey C. Cerier

发明人： Matthew D. Holcomb , Jason L. Harris , Michael J. Stokes , Mark S. Zeiner , Jonathan B. O'Keefe , Keith D. Boudreau , Jeffrey C. Cerier

IPC分类号： A61B17/068

CPC分类号： A61B17/0684 , A61B17/0644 , A61B17/0682 , A61B2017/0053 , A61B2017/00818 , A61B2017/0488 , A61B2017/0645 , A61B2017/0725

摘要： A surgical fastener applier having a handle and a fastener housing extending from the handle. The housing contains at least one anvil movable within the staple housing, the anvil has a proximal position and a distal position. When in the distal position a distal end of the anvil extends distal to the distal end of the staple housing. The housing contains a plurality of surgical fasteners each of which in the shape of a loop. At least one of the fasteners is placed around a portion of the anvil when in the distal position. The applier has a first mechanism for moving the anvil distally after a fastener has been deployed, and a second mechanism for moving the anvil distally after a fastener has been deployed. The second means is independent of the first means.

摘要翻译： 具有手柄和从手柄延伸的紧固件外壳的手术紧固件施加器。壳体包含至少一个在钉仓壳体内可移动的砧座，砧座具有近端位置和远端位置。当处于远端位置时，砧座的远端延伸到钉仓远端的远端。壳体包含多个环形形状的外科紧固件。当处于远端位置时，至少一个紧固件被放置在砧座的一部分周围。施放器具有用于在紧固件展开之后向远侧移动砧座的第一机构，以及用于在紧固件展开后向远侧移动砧座的第二机构。第二种手段是独立于第一种手段。

24.

发明授权
Powering implantable restriction systems using kinetic motion 有权
标题翻译：使用动力学动力为植入式限制系统提供动力

公开(公告)号：US08221439B2

公开(公告)日：2012-07-17

申请号：US12027820

申请日：2008-02-07

申请人： Daniel F. Dlugos, Jr. , Mark S. Ortiz , Amy L. Marcotte , David N. Plescia , Jason L. Harris , Mark S. Zeiner , Michael J. Stokes , Sean P. Conlon , David C. Yates

发明人： Daniel F. Dlugos, Jr. , Mark S. Ortiz , Amy L. Marcotte , David N. Plescia , Jason L. Harris , Mark S. Zeiner , Michael J. Stokes , Sean P. Conlon , David C. Yates

IPC分类号： A61B17/08

CPC分类号： A61F5/0059

摘要： Various powering devices are provided for transferring and/or generating energy from numerous sources to a communicating member implanted in a patient. The energy transferred to or generated by the communicating member can be used to provide power to an implantable restriction system configured to form a restriction in a pathway.

摘要翻译： 提供各种供电设备用于将许多来源的能量传递和/或产生到植入患者体内的连通构件。传递到通信构件或由通信构件产生的能量可以用于为配置成在路径中形成限制的可植入限制系统提供电力。

25.

发明申请
Pill Catchers 审中-公开
标题翻译：药丸捕手

公开(公告)号：US20120165792A1

公开(公告)日：2012-06-28

申请号：US12976648

申请日：2010-12-22

申请人： Mark S. Ortiz , Christopher J. Hess , Jason L. Harris , James T. Spivey , Michael J. Stokes , Thomas E. Albrecht , Mark S. Zeiner , Joseph Bernard Kraimer , James Anthony Topich , Daniel James Prenger

发明人： Mark S. Ortiz , Christopher J. Hess , Jason L. Harris , James T. Spivey , Michael J. Stokes , Thomas E. Albrecht , Mark S. Zeiner , Joseph Bernard Kraimer , James Anthony Topich , Daniel James Prenger

IPC分类号： A61M37/00

CPC分类号： A61M31/002 , A61B1/00147 , A61B1/041 , A61B5/07 , A61B5/4839

摘要： Devices and related methods arc provided for the controlled delivery of a therapeutic to a targeted location within a body. More particularly, methods and devices are provided for controlling the rate of passage of an orally administered pill through a body, as well as for controlling the delivery of a therapeutic within the pill at a specific location within the body. Various types of devices, generally referred to herein as “catchers,” are provided that can actively catch a pill as it passes through a body. The catcher can hold the pill at a specific location within the body until a predetermined event occurs, such as partial or complete. administration of a therapeutic within the pill. The catcher can then release the pill upon command and/or upon the occurrence of the predetermined event to allow the pill to pass out of the body. In other embodiments, various types of pills are provided that can actively engage a catcher and remain engaged with the catcher until a predetermined event occurs.

摘要翻译： 提供了设备和相关方法，用于将治疗剂控制递送到身体内的目标位置。更具体地，提供了用于控制经口给药的药丸通过身体的速率的方法和装置，以及用于控制体内在特定位置处的丸剂内的治疗剂的递送。提供了在本文中通常被称为“捕获器”的各种类型的装置，其可以在通过身体时主动地捕捉药丸。捕手可以将药丸保持在身体内的特定位置，直到发生预定事件，例如部分或完全。给药丸内的治疗剂。然后，捕手可以在命令和/或发生预定事件时释放药片以允许药丸从身体中流出。在其他实施例中，提供了可以主动地接合捕获器并保持与捕获器接合的各种类型的药丸，直到发生预定事件。

26.

发明申请
Intestinal Brake Inducing Intraluminal Therapeutic Substance Eluting Devices and Methods 审中-公开
标题翻译：肠制动诱导腔内治疗物质洗脱装置及方法

公开(公告)号：US20110295178A1

公开(公告)日：2011-12-01

申请号：US13104321

申请日：2011-05-10

申请人： Thomas E. Albrecht , Jeffrey L. Aldridge , Gregory J. Bakos , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , John V. Hunt , Prasanna Malaviya , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Suzanne Thompson , Richard W. Timm , James W. Voegele , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, JR. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski

发明人： Thomas E. Albrecht , Jeffrey L. Aldridge , Gregory J. Bakos , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , John V. Hunt , Prasanna Malaviya , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Suzanne Thompson , Richard W. Timm , James W. Voegele , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, JR. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski

IPC分类号： A61M5/00

CPC分类号： A61F5/0079 , A61K9/0065 , A61M5/14276 , A61M31/002 , A61M39/0208 , A61M2210/106 , A61M2210/1064

摘要： Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices may be accomplished via stabilized implantable systems and ingestible pills. In one aspect, a method of inducing satiety includes implanting an implant within a lumen of a gastrointestinal tract and retaining a portion of chyme that flows by the implant within a body of the implant. The method further involves re-releasing the retained chyme from the implant into the gastrointestinal tract at a predetermined rate slower than a rate caused by natural peristalsis.

摘要翻译： 方法和装置产生肠道制动效果，是非侵入性的或微创的，并且可以是可逆的。这些方法和装置可以通过稳定的可植入系统和可摄取的药丸来实现。一方面，一种诱导饱腹感的方法包括将植入物植入胃肠道的内腔中，并且将植入物流动的部分保持在植入物的体内。该方法还包括以比由天然蠕动引起的速率慢的预定速率将留置的食糜从植入物再释放到胃肠道中。

27.

发明申请
DEVICES AND METHODS FOR ADJUSTING A SATIATION AND SATIETY-INDUCING IMPLANTED DEVICE 审中-公开
标题翻译：调节和满意的诱导装置的装置和方法

公开(公告)号：US20100114148A1

公开(公告)日：2010-05-06

申请号：US12261078

申请日：2008-10-30

申请人： Thomas E. Albrecht , Jason L. Harris , Mark S. Ortiz , Amy L. Marcotte , Daniel F. Dlugos, JR. , Mark S. Zeiner , Michael J. Stokes , Jeremy D. Jarrett , Matthew D. Daniel

发明人： Thomas E. Albrecht , Jason L. Harris , Mark S. Ortiz , Amy L. Marcotte , Daniel F. Dlugos, JR. , Mark S. Zeiner , Michael J. Stokes , Jeremy D. Jarrett , Matthew D. Daniel

IPC分类号： A61M29/02

CPC分类号： A61F5/0036 , A61F5/004 , A61F5/0043 , A61F5/0046

摘要： An implant for placement within a hollow body organ having a member with an undeployed shape, for delivery within a hollow body, and one or more deployed shapes, for implantation therein. The member has sufficient rigidity in its deployed shape to exert an outward force against an interior of the hollow body so as to bring together two substantially opposing surfaces of the hollow body. The implant also includes a means for changing the deployed shape of the member while implanted within the hollow body.

摘要翻译： 一种植入物，用于放置在具有未展开形状的构件的空心体器官中，用于在中空体内输送，以及一个或多个展开形状，用于植入其中。该构件在其展开形状上具有足够的刚度以向中空体的内部施加向外的力，以将中空体的两个基本相对的表面组合在一起。植入物还包括用于在植入中空体内时改变构件的展开形状的装置。

28.

发明授权
Intestinal brake inducing intraluminal therapeutic substance eluting devices and methods 有权
标题翻译：肠内制动诱导管腔内治疗物质洗脱装置及方法

公开(公告)号：US08876761B2

公开(公告)日：2014-11-04

申请号：US13104313

申请日：2011-05-10

申请人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, Jr. , Jason L. Harris , Christopher J. Hess , Prasanna Malaviya , Glenda C. Marsh , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , James W. Voegele , Lauren S. Weaner , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, Jr. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski

发明人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, Jr. , Jason L. Harris , Christopher J. Hess , Prasanna Malaviya , Glenda C. Marsh , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , James W. Voegele , Lauren S. Weaner , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, Jr. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski

IPC分类号： A61M31/00 , A61K9/00 , A61M5/142 , A61F5/00 , A61N1/05 , A61M39/02 , A61F2/04 , A61N1/36 , A61N1/372

CPC分类号： A61M31/002 , A61F2/04 , A61F5/0013 , A61F5/0026 , A61F2002/045 , A61K9/0065 , A61M5/14276 , A61M39/0208 , A61M2210/106 , A61M2210/1064 , A61N1/0509 , A61N1/36007 , A61N1/37205

摘要： Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems and ingestible pills. In one embodiment, a method of producing satiety comprising the steps of accessing a gastrointestinal tract of a patient and implanting an intraintestinal therapeutic substance eluting implant. The implant is capable of eluting a satiety inducing substance selected from at least one of a nutrient, a specific satiety inducing bio-active substance, pancreatic polypeptides, free fatty acids, cholecystokinin, amino acids, glutamine, lipids, linoleic acid, or a combination thereof, from the implant into the gastrointestinal tract.

摘要翻译： 方法和装置产生肠道制动效果，是非侵入性的或微创的，并且可以是可逆的。这些方法和装置通过稳定的可植入系统和可摄取的药丸来实现。在一个实施方案中，产生饱腹感的方法包括以下步骤：进入患者的胃肠道并植入肠内治疗物质洗脱植入物。植入物能够洗脱选自营养物，特定饱腹感生物活性物质，胰腺多肽，游离脂肪酸，缩胆囊素，氨基酸，谷氨酰胺，脂质，亚油酸或组合中的至少一种的饱腹感受物质从植入物到胃肠道。