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公开(公告)号：US20080172117A1
公开(公告)日：2008-07-17
申请号：US11622538
申请日：2007-01-12
IPC分类号： A61N1/372
CPC分类号： A61N1/0553 , A61N1/0558
摘要： A medical system for electrical stimulation includes a first column of electrodes, a second column of electrodes, an expandable member disposed between first and second columns, and an expansion mechanism adapted to transmit an externally applied pressure to the expandable member. The pressure expands the expandable member in order to force the first column of electrodes apart from the second column of electrodes. The first and second columns, disposed side-by-side, may be inserted through a percutaneous needle and into a epidural space, alongside a spinal cord; after insertion, the first column may be forced apart from the second column by applying the pressure to the expandable member.
摘要翻译： 用于电刺激的医疗系统包括第一列电极，第二电极列，设置在第一和第二列之间的可扩张构件以及适于将外部施加的压力传递到可扩张构件的膨胀机构。 压力使可膨胀构件膨胀，以迫使第一列电极与第二列电极分开。 并排设置的第一和第二列可以穿过经皮针插入到与脊髓一起的硬膜外腔中; 在插入之后，通过向可膨胀构件施加压力，第一柱可以被迫离开第二柱。
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公开(公告)号：US20080140008A1
公开(公告)日：2008-06-12
申请号：US11951771
申请日：2007-12-06
CPC分类号： A61M27/006 , A61M25/0102 , A61M25/0108 , A61M2025/0059 , A61M2025/0063 , A61M2025/0293
摘要： An intrathecal catheter for delivering fluid to, or withdrawing fluid from, the cerebrospinal fluid compartment of a patient, includes a proximal end and a distal portion. The distal portion has an outer diameter of about 1 mm or less, a bending stiffness of about 0.002 pounds per square inch or less, and a distal end. A delivery region is located between the proximal end and the distal end, and a lumen extends from the proximal end to the delivery region. The catheter may further include a coiled structure region to prevent dislodgement of the catheter from a tissue in which the coiled structure is implanted, for example the cisterna magna. The catheter may also include tines to anchor portions of the catheter, for example to a portion of the spinal canal.
摘要翻译： 用于将流体输送到患者的脑脊液腔室或从患者的脑脊液腔室排出流体的鞘内导管包括近端和远端部分。 远侧部分具有约1mm或更小的外径，约0.002磅/平方英寸或更小的弯曲刚度和远端。 输送区域位于近端和远端之间，并且内腔从近端延伸到输送区域。 导管还可以包括螺旋结构区域，以防止导管从其中植入线圈结构的组织例如大便池移出。 导管还可以包括用于锚定导管的部分的齿，例如到椎管的一部分。
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公开(公告)号：US5968085A
公开(公告)日：1999-10-19
申请号：US63170
申请日：1998-04-20
申请人： Mary M. Morris , David Lipson
发明人： Mary M. Morris , David Lipson
CPC分类号： A61N1/056 , A61B8/0833 , A61N2001/0578
摘要： A pacing lead of the type having a hollow lead body with a conductor linking the electrode at one end with the connector at the other end has a guide wire or stylet either connected to a mechanical vibrator or carrying an ultrasonic transducer in order to cause the guidewire to move within the body to facilitate the display of the catheter position on external ultrasonic monitoring equipment.
摘要翻译： 具有中空引线体的类型的起搏引线具有将一端的电极与另一端的连接器连接的导体，具有连接到机械振动器或承载超声波换能器的引导线或探针，以便引导导丝 在体内移动以便于在外部超声波监测设备上显示导管位置。
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公开(公告)号：US5871530A
公开(公告)日：1999-02-16
申请号：US62373
申请日：1998-04-17
申请人： Terrell M. Williams , Peter M. J. Mulier , John G. Keimel , Timothy G. Laske , Gregory A. Boser , Mary M. Morris , Xiaoyi Min
发明人： Terrell M. Williams , Peter M. J. Mulier , John G. Keimel , Timothy G. Laske , Gregory A. Boser , Mary M. Morris , Xiaoyi Min
CPC分类号： A61N1/0565 , A61N1/0563
摘要： A lead and a lead system for dispersion of a cardioversion/defibrillation electrode formed of one or more small diameter defibrillation electrodes in a heart chamber and for attaching a pace/sense electrode in contact with the heart. The small diameter defibrillation electrode or electrodes extend distally from the distal end of the lead body. If multiple electrodes are employed, they are preferably biased to spread apart when unrestrained and have a cross-section size small enough to be inserted into interstices of trabeculae in the ventricular chamber. The distal ends of the defibrillation electrodes may be free of attachment to the lead body or may be attached by a weak bond to the distal portion of the lead.
摘要翻译： 一种用于在心室中由一个或多个小直径除颤电极形成的复律/除颤电极的分散的引线和引导系统，并且用于附接与心脏接触的步调/感测电极。 小直径除颤电极或电极从引线体的远端向远端延伸。 如果使用多个电极，则它们优选地被偏置以在不受限制的情况下展开，并且具有足够小的横截面尺寸以插入心室中的小梁的间隙中。 除颤电极的远端可以没有附着到引线体，或者可以通过弱接合附着到引线的远端部分。
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25.发明授权
公开(公告)号：US5830329A
公开(公告)日：1998-11-03
申请号：US881343
申请日：1997-06-24
CPC分类号： B29C59/142 , B29K2083/00 , B29L2031/753 , B29L2031/7534
摘要： This invention relates to the preferential glow discharge at the inside diameter (ID) of plastic tubing, particularly very small tubing.
摘要翻译： 本发明涉及塑料管的内径（ID）上的优先辉光放电，特别是非常小的管。
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公开(公告)号：US5713867A
公开(公告)日：1998-02-03
申请号：US639660
申请日：1996-04-29
申请人： Mary M. Morris
发明人： Mary M. Morris
CPC分类号： A61M25/0668 , A61M25/0017 , A61M25/005
摘要： An introducer system featuring a sheath which is kink resistant. Such a sheath thereby permits the sheath to be dramatically bent while still allowing a lead to be introduced therethrough. The kink resistance is provided by a composite construction of the sheath. In particular the sheath has at least one integral reinforcing fiber. In the preferred embodiment the reinforcing fibers are provided in a braided configuration. The sheath preferably is constructed to be readily split using a slitter in a longitudinal direction and thus permits the sheath to be removed from the venous system without having to withdrawn the sheath over an end of the pacemaker lead. In an alternate embodiment the sheath is scored, including the reinforcing fibers, to thereby permit the sheath to be longitudinally split apart and removed from the venous system without having to withdrawn the sheath over an end of the pacemaker lead.
摘要翻译： 具有抗扭结护套的导引器系统。 这样的护套因此允许护套被显着地弯曲，同时仍然允许引线被引入其中。 扭结阻力由护套的复合结构提供。 特别地，护套具有至少一个整体增强纤维。 在优选实施例中，增强纤维以编织构造提供。 护套优选构造成使用纵向方向上的切割器容易地分开，并且因此允许护套从静脉系统移除，而不必将起重器引线的端部拉出。 在一个替代实施例中，护套被刻痕，包括增强纤维，从而允许护套纵向分离并从静脉系统中移除，而不必将起重器引线的端部取出。
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公开(公告)号：US08784800B2
公开(公告)日：2014-07-22
申请号：US12400059
申请日：2009-03-09
CPC分类号： A61K35/28 , A61B5/06 , A61B5/7285 , A61B6/12 , A61B6/481 , A61B6/487 , A61B6/541 , A61K35/39 , A61K49/0017 , A61K49/06
摘要： A method of delivering therapy to a target site. The method includes (a) obtaining a base image of the target site, (b) injecting a dose of a mix of a therapeutic agent and a contrast agent into a first injection location at the target site via a needle passing through a catheter, (c) collecting sequential fluoroscopic images of a contrast agent dispersion cloud at the first injection location, (d) determining a contrast agent dispersion area from the sequential fluoroscopic images, (e) determining a therapeutic agent dispersion area from the contrast agent dispersion area, (f) marking the therapeutic agent dispersion area on the base image of the target site, and (g) repeating (b) through (f) until the target site is substantially covered with overlapping therapeutic agent dispersion areas corresponding to a plurality of injections at a plurality of injection locations at the target site.
摘要翻译： 将治疗递送到目标部位的方法。 该方法包括（a）获得目标部位的基础图像，（b）通过穿过导管的针将目标部位的剂量的治疗剂和造影剂的剂量注射到目标部位的第一注射位置（ c）在第一注射位置处收集造影剂分散云的顺序透视图像，（d）从顺序透视图像确定造影剂分散区域，（e）从造影剂分散区域确定治疗剂分散区域（ f）在目标部位的基础图像上标记治疗剂分散区域，和（g）重复（b）到（f）直到目标部位基本上覆盖有与多个注射相对应的重叠治疗剂分散区域 在目标地点的多个注射位置。
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公开(公告)号：US08672917B2
公开(公告)日：2014-03-18
申请号：US12767224
申请日：2010-04-26
IPC分类号： A61M31/00
CPC分类号： A61B5/036 , A61B5/0031 , A61B5/0215 , A61B5/4839 , A61M5/14276 , A61M5/16854 , A61M5/1723 , A61M2005/1726 , A61M2205/3331 , A61M2205/3334
摘要： A method for adjusting delivery of a therapeutic fluid to a patient suffering from or at risk of pulmonary arterial hypertension includes introducing the therapeutic fluid to a patient via a catheter at a predetermined rate. The catheter is positioned to deliver the fluid to the right ventricle or the pulmonary artery. The catheter a one-way valve configured to allow the fluid to flow from the catheter to the target location. The method further includes monitoring pressure of the target location by monitoring internal catheter pressure, and adjusting the rate at which the therapeutic fluid is introduced to the catheter based on the monitored pressure. The rate at which the fluid is introduced to the catheter is increased if internal catheter pressure increases, and the rate at which the fluid is introduced to the catheter is decreased if the internal catheter pressure decreases.
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公开(公告)号：US08369965B2
公开(公告)日：2013-02-05
申请号：US12846547
申请日：2010-07-29
IPC分类号： A61N1/05
CPC分类号： A61N1/0553 , A61N1/0558
摘要： A medical system for electrical stimulation includes a first column of electrodes, a second column of electrodes, an expandable member disposed between first and second columns, and an expansion mechanism adapted to transmit an externally applied pressure to the expandable member. The pressure expands the expandable member in order to force the first column of electrodes apart from the second column of electrodes. The first and second columns, disposed side-by-side, may be inserted through a percutaneous needle and into a epidural space, alongside a spinal cord; after insertion, the first column may be forced apart from the second column by applying the pressure to the expandable member.
摘要翻译： 用于电刺激的医疗系统包括第一列电极，第二电极列，设置在第一和第二列之间的可扩张构件以及适于将外部施加的压力传递到可扩张构件的膨胀机构。 压力使可膨胀构件膨胀，以迫使第一列电极与第二列电极分开。 并排设置的第一和第二列可以穿过经皮针插入到与脊髓一起的硬膜外腔中; 在插入之后，通过向可膨胀构件施加压力，第一柱可以被迫离开第二柱。
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30.发明授权Radiopaque marking of lead electrode zone in a continuous conductor construction 失效连续导体结构中铅电极区的不透射线标记公开(公告)号：US07925358B2
公开(公告)日：2011-04-12
申请号：US11846774
申请日：2007-08-29
IPC分类号： A61N1/06
CPC分类号： A61N1/0563
摘要： A cardiac transvenous defibrillation lead has a continuous coil conductor within a layer of insulation. A portion of the coil conductor is exposed as a defibrillation electrode. In order to enhance fluoroscopic visualization of the exposed electrode during implant, the end of the exposed electrode is marked with a radiopaque element. The element may be in the form of an adhesive filled with radiopaque material that is used to backfill under the layer of insulation. Alternatively, a tube made of radiopaque material may be installed between the layer of insulation and the coil conductor.
摘要翻译： 心脏静脉除颤引线在绝缘层内具有连续的线圈导体。 线圈导体的一部分作为除颤电极露出。 为了在植入期间增强暴露电极的荧光透视可视化，暴露电极的端部用不透射线的元件标记。 元件可以是填充有不透射线材料的粘合剂的形式，其用于在绝缘层下方回填。 或者，由不透射线材料制成的管可以安装在绝缘层和线圈导体之间。
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