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    Intracardiac defibrillation leads
    1.
    发明授权
    Intracardiac defibrillation leads 失效
    心脏除颤引导

    公开(公告)号：US5871530A

    公开(公告)日：1999-02-16

    申请号：US62373

    申请日：1998-04-17

    申请人： Terrell M. Williams ,  Peter M. J. Mulier ,  John G. Keimel ,  Timothy G. Laske ,  Gregory A. Boser ,  Mary M. Morris ,  Xiaoyi Min

    发明人： Terrell M. Williams ,  Peter M. J. Mulier ,  John G. Keimel ,  Timothy G. Laske ,  Gregory A. Boser ,  Mary M. Morris ,  Xiaoyi Min

    IPC分类号： A61N1/04 ,  A61N1/05

    CPC分类号： A61N1/0565 ,  A61N1/0563

    摘要： A lead and a lead system for dispersion of a cardioversion/defibrillation electrode formed of one or more small diameter defibrillation electrodes in a heart chamber and for attaching a pace/sense electrode in contact with the heart. The small diameter defibrillation electrode or electrodes extend distally from the distal end of the lead body. If multiple electrodes are employed, they are preferably biased to spread apart when unrestrained and have a cross-section size small enough to be inserted into interstices of trabeculae in the ventricular chamber. The distal ends of the defibrillation electrodes may be free of attachment to the lead body or may be attached by a weak bond to the distal portion of the lead.

    摘要翻译： 一种用于在心室中由一个或多个小直径除颤电极形成的复律/除颤电极的分散的引线和引导系统，并且用于附接与心脏接触的步调/感测电极。 小直径除颤电极或电极从引线体的远端向远端延伸。 如果使用多个电极，则它们优选地被偏置以在不受限制的情况下展开，并且具有足够小的横截面尺寸以插入心室中的小梁的间隙中。 除颤电极的远端可以没有附着到引线体，或者可以通过弱接合附着到引线的远端部分。

    Implantable defibrillator and lead system
    2.
    发明授权
    Implantable defibrillator and lead system 失效
    植入式除颤器和引导系统

    公开(公告)号：US6038472A

    公开(公告)日：2000-03-14

    申请号：US840691

    申请日：1997-04-29

    申请人： Terrell M. Williams ,  Peter M. J. Mulier ,  John G. Keimel ,  Timothy G. Laske ,  Gregory A. Boser ,  Mary M. Morris ,  Xiaoyi Min

    发明人： Terrell M. Williams ,  Peter M. J. Mulier ,  John G. Keimel ,  Timothy G. Laske ,  Gregory A. Boser ,  Mary M. Morris ,  Xiaoyi Min

    IPC分类号： A61N1/04 ,  A61N1/05 ,  A61N1/39

    CPC分类号： A61N1/0565 ,  A61N1/0563

    摘要： A lead and a lead system for dispersion of a cardioversion/defibrillation electrode formed of one or more small diameter defibrillation electrodes in a heart chamber and for attaching a pace/sense electrode in contact with the heart. The small diameter defibrillation electrode or electrodes extend distally from the distal end of the lead body. If multiple electrodes are employed, they are preferably biased to spread apart when unrestrained and have a cross-section size small enough to be inserted into interstices of trabeculae in the ventricular chamber. The distal ends of the defibrillation electrodes may be free of attachment to the lead body or may be attached by a weak bond to the distal portion of the lead.

    摘要翻译： 一种用于在心室中由一个或多个小直径除颤电极形成的复律/除颤电极的分散的引线和引导系统，并且用于附接与心脏接触的步调/感测电极。 小直径除颤电极或电极从引线体的远端向远端延伸。 如果使用多个电极，则它们优选地被偏置以在不受限制的情况下展开，并且具有足够小的横截面尺寸以插入心室中的小梁的间隙中。 除颤电极的远端可以没有附着到引线体，或者可以通过弱接合附着到引线的远端部分。

    Intracardiac defibrillation leads
    3.
    发明授权
    Intracardiac defibrillation leads 失效
    心脏除颤引导

    公开(公告)号：US06178355B1

    公开(公告)日：2001-01-23

    申请号：US09216293

    申请日：1998-12-18

    申请人： Terrell M. Williams ,  Peter M. J. Mulier ,  John G. Keimel ,  Timothy G. Laske ,  Gregory A. Boser ,  Mary M. Morris ,  Xiaoyi Min

    发明人： Terrell M. Williams ,  Peter M. J. Mulier ,  John G. Keimel ,  Timothy G. Laske ,  Gregory A. Boser ,  Mary M. Morris ,  Xiaoyi Min

    IPC分类号： A61N105

    CPC分类号： A61N1/0565 ,  A61N1/0563

    摘要： A lead and a lead system for dispersion of a cardioversion/defibrillation electrode formed of one or more small diameter defibrillation electrodes in a heart chamber and for attaching a pace/sense electrode in contact with the heart. The small diameter defibrillation electrode or electrodes extend distally from the distal end of the lead body. If multiple electrodes are employed, they are preferably biased to spread apart when unrestrained and have a cross-section size small enough to be inserted into interstices of trabeculae in the ventricular chamber. The distal ends of the defibrillation electrodes may be free of attachment to the lead body or may be attached by a weak bond to the distal portion of the lead.

    摘要翻译： 一种用于在心室中由一个或多个小直径除颤电极形成的复律/除颤电极的分散的引线和引导系统，并且用于附接与心脏接触的步调/感测电极。 小直径除颤电极或电极从引线体的远端向远端延伸。 如果使用多个电极，则它们优选地被偏置以在不受限制的情况下展开，并且具有足够小的横截面尺寸以插入心室中的小梁的间隙中。 除颤电极的远端可以没有附着到引线体，或者可以通过弱接合附着到引线的远端部分。

    Electrode for His bundle stimulation
    4.
    发明授权
    Electrode for His bundle stimulation 失效
    电极为他的束刺激

    公开(公告)号：US06937897B2

    公开(公告)日：2005-08-30

    申请号：US10261750

    申请日：2002-09-30

    申请人： Xiaoyi Min ,  Terrell M. Williams

    发明人： Xiaoyi Min ,  Terrell M. Williams

    IPC分类号： A61N1/05 ,  A61N1/00

    CPC分类号： A61N1/056 ,  A61N1/0573

    摘要： An electrical lead equipped with cathode and anode active succession electrodes for positioning in the vicinity of the His bundle tissue. The lead includes a lead body for carrying conductors coupled between electrodes located at or near the distal lead end and a connector assembly located at the proximal lead end for connecting to an implantable pacemaker. The electrode is shaped, at the distal end, for positioning and attachment in the His bundle and branches thereof, cathode and anode electrodes co-extensive with the lead body. The cathode and anode electrodes may be helical screw-in type or equivalent electrodes adapted for secure fixation deep within the His bundle tissue or the tissue in the vicinity of the His bundle.

    摘要翻译： 配备有用于定位在His束组织附近的阴极和阳极活性连续电极的电引线。 引线包括用于承载耦合在位于远端引线端处或附近的电极之间的导体的引线体和位于近端引导端的用于连接到可植入起搏器的连接器组件。 电极在远端成形，用于定位和附着在His束及其分支中，阴极和阳极电极与引线体共同延伸。 阴极电极和阳极电极可以是螺旋螺旋型或等效电极，其适于牢固地固定在His束组织内或His束附近的组织内。

    J-shaped coronary sinus lead
    5.
    发明授权
    J-shaped coronary sinus lead 有权
    J型冠状窦导联

    公开(公告)号：US06321123B1

    公开(公告)日：2001-11-20

    申请号：US09264609

    申请日：1999-03-08

    申请人： Mary M. Morris ,  Xiaoyi Min

    发明人： Mary M. Morris ,  Xiaoyi Min

    IPC分类号： A61N105

    CPC分类号： A61N1/056 ,  A61N2001/0585

    摘要： The lead configuration enhances the sensing characteristics of the lead and provides for stable location of the electrodes in the coronary sinus. The J-shaped bend in the distal portion of the lead body spaces the distal tip of the lead body less than about 0.9 inches laterally from the portion of the lead body that is proximal to the bend. The tip of the lead body is provided with a pacing/sensing electrode and the curved portion of the J-shaped bend carries an elongated coil electrode that serves as an indifferent electrode for pacing and sensing. For left atrial pacing, the lead tip electrode is located adjacent the wall of the coronary sinus closest to the left atrium, and the indifferent electrode is located adjacent the opposite wall of the coronary sinus, closer to the left ventricle. To enhance spatial distribution of the indifferent electrode and provide for greater averaging of the ventricular signal, which in turn reduces the far field of the ventricular signal, the indifferent electrode extends over 10-50 millimeters or multiple spaced indifferent electrodes are used.

    摘要翻译： 引线配置增强引线的感测特性，并提供电极在冠状窦中的稳定位置。 引线主体的远端部分中的J形弯曲部分使引线主体的远端部从导线本体的靠近弯头的部分横向偏离约0.9英寸。 引线体的尖端设置有起搏/感测电极，并且J形弯曲部的弯曲部分承载用作起搏和感测的无关电极的细长线圈电极。 对于左心房起搏，引导尖端电极位于最靠近左心房的冠状窦壁附近，而无关电极位于冠状窦的相对壁附近，靠近左心室。 为了增强无关电极的空间分布，并提供更大的心室信号的平均值，这进一步减少心室信号的远场，无差异的电极延伸超过10-50毫米或使用多个间隔的无关电极。

    Systems and methods for assessing heart failure and controlling cardiac resynchronization therapy using hybrid impedance measurement configurations
    6.
    发明授权
    Systems and methods for assessing heart failure and controlling cardiac resynchronization therapy using hybrid impedance measurement configurations 有权
    用于评估心力衰竭并使用混合阻抗测量配置控制心脏再同步治疗的系统和方法

    公开(公告)号：US08750981B2

    公开(公告)日：2014-06-10

    申请号：US13217554

    申请日：2011-08-25

    申请人： Gene A. Bornzin ,  Xiaoyi Min ,  Laurence S. Sloman ,  Steve Koh

    发明人： Gene A. Bornzin ,  Xiaoyi Min ,  Laurence S. Sloman ,  Steve Koh

    IPC分类号： A61B5/05 ,  A61B5/053 ,  A61N1/36 ,  A61N1/368 ,  A61B5/0205

    CPC分类号： A61B5/053 ,  A61B5/0205 ,  A61B5/0538 ,  A61B5/686 ,  A61N1/36185 ,  A61N1/3627 ,  A61N1/3686

    摘要： Techniques are provided for use with an implantable medical device for detecting and assessing heart failure and for controlling cardiac resynchronization therapy (CRT) based on impedance signals obtained using hybrid impedance configurations. The hybrid configurations exploit right atrial (RA)-based impedance measurement vectors and/or left ventricular (LV)-based impedance measurement vectors. In one example, current is injected between the device case and a ring electrode in the right ventricle (RV) or RA. RA-based impedance values are measured along vectors between the device case and an RA electrode. LV-based impedance values are measured along vectors between the device case and one or more electrodes of the LV. Heart failure and other cardiac conditions are detected and tracked using the measured impedance values. CRT delay parameters are also optimized based impedance. In this manner, multiple hybrid impedance measurement configurations are exploited whereby different vectors are used to inject current and measure impedance.

    摘要翻译： 提供技术用于可植入医疗装置，用于基于使用混合阻抗配置获得的阻抗信号来检测和评估心力衰竭并用于控制心脏再同步治疗（CRT）。 混合配置利用基于右心房（RA）的阻抗测量向量和/或左心室（LV））的阻抗测量向量。 在一个示例中，电流注入到装置壳体和右心室（RV）或RA中的环形电极之间。 基于RA的阻抗值是沿器件壳体和RA电极之间的矢量测量的。 基于LV的阻抗值在器件壳体和LV的一个或多个电极之间的矢量上测量。 使用测量的阻抗值检测和跟踪心力衰竭和其他心脏状况。 CRT延迟参数也是基于阻抗的优化。 以这种方式，利用多个混合阻抗测量配置，由此使用不同的矢量来注入电流并测量阻抗。

    Implantable lead assembly having a plurality of inductors
    8.
    发明授权
    Implantable lead assembly having a plurality of inductors 有权
    具有多个电感器的可植入引线组件

    公开(公告)号：US08600520B2

    公开(公告)日：2013-12-03

    申请号：US13449897

    申请日：2012-04-18

    申请人： Phong D. Doan ,  Xiaoyi Min ,  Virote Indravudh

    发明人： Phong D. Doan ,  Xiaoyi Min ,  Virote Indravudh

    IPC分类号： A61N1/00

    CPC分类号： A61N1/05 ,  A61N1/086 ,  A61N1/3605 ,  A61N1/362 ,  H01F5/02 ,  H01F2005/025 ,  Y10T29/49002 ,  Y10T29/49071

    摘要： In accordance with an embodiment, an implantable lead assembly is provided comprised of an elongated body including a distal end, a proximal end having a header connector portion for coupling the elongated body with an implantable medical device, and an intermediate segment located between the distal and proximal ends. An intermediate electrode is disposed at the intermediate segment along the elongated body. A conductor is disposed in the elongated body and electrically coupled with the header connector portion and the intermediate electrode. The conductor wound within the intermediate segment to form first and second inductive coils that are axially separated from each other by an inter-coil gap, wherein the first and second inductive coils have different self-resonant frequencies.

    摘要翻译： 根据一个实施例，提供一种可植入引线组件，其包括细长主体，其包括远端，近端具有用于将细长主体与可植入医疗装置连接的插头连接器部分，以及位于远端和 近端 中间电极沿着细长体设置在中间部分。 导体设置在细长主体中并与插头连接器部分和中间电极电耦合。 导体缠绕在中间段内以形成通过线圈间隙彼此轴向分离的第一和第二感应线圈，其中第一和第二感应线圈具有不同的自谐振频率。

    SYSTEMS AND METHODS FOR DETERMINING INDUCTANCE AND CAPACITANCE VALUES FOR USE WITH LC FILTERS WITHIN IMPLANTABLE MEDICAL DEVICE LEADS TO REDUCE LEAD HEATING DURING MRI
    10.
    发明申请
    SYSTEMS AND METHODS FOR DETERMINING INDUCTANCE AND CAPACITANCE VALUES FOR USE WITH LC FILTERS WITHIN IMPLANTABLE MEDICAL DEVICE LEADS TO REDUCE LEAD HEATING DURING MRI 有权
    用于确定电导率和电容值的系统和方法，用于在可植入医疗器械中使用LC过滤器，在MRI期间减少引线加热

    公开(公告)号：US20130123876A1

    公开(公告)日：2013-05-16

    申请号：US11955268

    申请日：2007-12-12

    申请人： Xiaoyi Min

    发明人： Xiaoyi Min

    IPC分类号： A61N1/375

    CPC分类号： A61N1/056 ,  A61N1/086 ,  A61N1/3718 ,  G01R33/3685

    摘要： Techniques are provided for configuring filters for reducing heating within pacing/sensing leads of a pacemaker or implantable cardioverter-defibrillator that might occur due to induced currents during a magnetic resonance imaging (MRI) procedure or in the presence of other sources of strong radio frequency (RF) fields. In particular, techniques are provided for selecting inductors and capacitors for use in LC filters while taking into account the tolerances of the component devices, as well as the target impedance of the components and the particular RF frequencies to be filtered.

    摘要翻译： 提供了用于配置用于减少起搏器或植入式心律转复除颤器的起搏/感测引线内的加热的技术，其可能由于在磁共振成像（MRI）程序期间的感应电流或其它强射频源的存在而发生 RF）字段。 特别地，提供了用于选择用于LC滤波器的电感器和电容器的技术，同时考虑到组件装置的公差以及组件的目标阻抗和要滤波的特定RF频率。