-
公开(公告)号：US20190083976A1
公开(公告)日：2019-03-21
申请号：US16210165
申请日：2018-12-05
发明人： Eli N. Glezer , Sudeep Kumar , Pankaj Oberoi , George Sigal , Michael Tsionsky
IPC分类号： B01L3/00 , C12Q1/6804 , G01N33/68 , G01N33/543 , C12Q1/6876 , C12Q1/6816
摘要： The invention relates to methods for conducting solid-phase binding assays. One example is an assay method having improved analyte specificity where specificity is limited by the presence of non-specific binding interactions.
-
22.发明申请公开(公告)号：US20180238882A1
公开(公告)日：2018-08-23
申请号：US15886020
申请日：2018-02-01
发明人： Michael Tsionsky , Eli N. Glezer , Selen Stromgren , George Sigal , Jonathan K. Leland , Mark A. Billadeau , Svetlana Leytner , Mark Martin , Larry Helms
IPC分类号： G01N33/573 , G01N33/58 , C12Q1/48 , G01N21/76 , G01N33/53 , G01N33/543
摘要： The invention relates to improved electrochemiluminescence assay methods for phosphorylated peptides or proteins employing phospho-specific antibodies and buffer compositions that are substantially free of inorganic phosphate.
-
公开(公告)号：US20140255916A1
公开(公告)日：2014-09-11
申请号：US14285086
申请日：2014-05-22
发明人： George Sigal
IPC分类号： G01N33/569
CPC分类号： G01N33/56983 , G01N33/54313 , G01N33/566 , G01N2500/02
摘要： The invention provides methods and kits for measuring the ability of a test sample to inhibit the binding of a receptor expressed by a pathogen to a host cell ligand of the pathogen.
摘要翻译： 本发明提供了用于测量测试样品抑制由病原体表达的受体与病原体的宿主细胞配体的结合的能力的方法和试剂盒。
-
公开(公告)号：US11951483B2
公开(公告)日：2024-04-09
申请号：US17215962
申请日：2021-03-29
发明人： Eli N. Glezer , Sudeep Kumar , Pankaj Oberoi , George Sigal , Michael Tsionsky
IPC分类号： G01N33/543 , B01L3/00 , C12Q1/6804 , C12Q1/6816 , C12Q1/6876 , G01N33/68
CPC分类号： B01L3/50853 , C12Q1/6804 , C12Q1/6816 , C12Q1/6876 , G01N33/54306 , G01N33/54353 , G01N33/6845 , B01L2300/021 , B01L2300/043 , B01L2300/0609 , B01L2300/0829 , G01N2458/10 , C12Q1/6816 , C12Q2563/131
摘要： The invention relates to methods for conducting solid-phase binding assays. One example is an assay method having improved analyte specificity where specificity is limited by the presence of non-specific binding interactions.
-
公开(公告)号：US11927592B2
公开(公告)日：2024-03-12
申请号：US17813722
申请日：2022-07-20
CPC分类号： G01N33/58 , G01N21/66 , G01N2458/30
摘要： The present disclosure provides compositions, reagents, kits, systems, system components, and methods for performing assays. More particularly, the disclosure relates to an assay composition for detecting luminescence, which comprises an alkyl diethanolamine, for example, N-butyldiethanolamine (BDEA). In emodiments, the assay composition comprises 2-dibutylaminoethanol (BDAE).
-
公开(公告)号：US11896978B2
公开(公告)日：2024-02-13
申请号：US17032524
申请日：2020-09-25
发明人： Eli N. Glezer , Stephen Higgins , Sandor Kovacs , Sudeep Kumar , Kenneth Page , Kristian Roth , George Sigal
CPC分类号： B01L7/525 , B01L3/5027 , B01L2200/027 , B01L2200/0605 , B01L2200/0621 , B01L2200/0631 , B01L2200/10 , B01L2200/146 , B01L2200/16 , B01L2300/0645 , B01L2300/087 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2300/0883 , B01L2400/0487 , B01L2400/0688 , B01L2400/0694 , C12Q1/686
摘要： Assay cartridges are described that have purification, reaction, and detection zones and other fluidic components which can include sample chambers, waste chambers, conduits, vents, reagent chambers, reconstitution chambers and the like. The assay cartridges are used to conduct multiplexed nucleic acid measurements. Also described are kits including such cartridges, methods of using the same, and a reader configured to analyze an assay conducted using an assay cartridge.
-
公开(公告)号：US20220057362A1
公开(公告)日：2022-02-24
申请号：US17407667
申请日：2021-08-20
发明人： Mark Billadeau , Nicholas Carbone , Charles Clinton , Scott Dowdell , Manish Kochar , Nicholas Fox-Lyon , Bandele Jeffrey-Coker , Alexander Tucker-Schwartz , George Sigal , Gisbert Spieles , Jules Vandersarl , Jacob Wohlstadter
IPC分类号： G01N27/49 , G01N27/327
摘要： An electrochemical cell includes a plurality of working electrode zones disposed, and defining a pattern, on a surface of the cell and at least one auxiliary electrode disposed on the surface. The auxiliary electrode may have a defined interfacial potential.
-
公开(公告)号：US11231417B2
公开(公告)日：2022-01-25
申请号：US16815598
申请日：2020-03-11
发明人： Sudeep Kumar , George Sigal , Michael Tsionsky
IPC分类号： G01N33/543 , G01N33/53 , C12Q1/6823 , C12Q1/6832 , C12Q1/6834
摘要： The invention relates to methods for conducting binding assays in an assay device that includes one or more storage and use zone. The storage zones of the assay device are configured to house one or more reagents used in an assay conducted in the use zone of the device.
-
公开(公告)号：US20210172937A1
公开(公告)日：2021-06-10
申请号：US17026561
申请日：2020-09-21
发明人： Eli N. Glezer , Kent Johnson , Michael Tsionsky , John H. Kenten , Jeff D. Debad , Robert M. Umek , Paula Denney Eason , Hans Biebuyck , Jacob N. Wohlstadter , James Wilbur , George Sigal , Niranjan Y. Sardesai
IPC分类号： G01N33/53 , C12Q1/48 , G01N33/543 , G01N33/68 , G01N33/569 , G01N33/573
摘要： Multiplexed test measurements are conducted using an assay module having a plurality of assay domains. In preferred embodiments, these measurements are conducted in assay modules having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
-
公开(公告)号：US10782227B2
公开(公告)日：2020-09-22
申请号：US16845560
申请日：2020-04-10
发明人： Jacob N. Wohlstadter , Eli Glezer , James Wilbur , George Sigal , Kent Johnson , Charles Clinton , Alan Kishbaugh , Bandele Jeffrey-Coker , Jeff D. Debad , Alan B. Fischer
摘要： Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
-
-
-
-
-
-
-
-
-
搜索结果
79 条记录 (耗时 0.024 秒)
