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21.发明授权Methods and systems for stimulating a nerve originating in an upper cervical spine area to treat a medical condition 有权用于刺激源自上颈椎区域的神经以治疗医疗状况的方法和系统公开(公告)号：US07493172B2
公开(公告)日：2009-02-17
申请号：US11073078
申请日：2005-03-04
IPC分类号： A61N1/00
CPC分类号： A61M5/14276 , A61M5/1723 , A61M2205/3523 , A61M2205/52 , A61M2205/8243 , A61N1/36071 , A61N1/37205 , Y10T307/484
摘要： Methods of treating a medical condition of a patient include applying at least one stimulus to a target nerve within the patient with an implanted system control unit in accordance with one or more stimulation parameters. The target nerve may include any nerve originating in an upper cervical spine area of the patient or a branch of any nerve originating in the upper cervical spine area of the patient. Systems for treating a medical condition of a patient include a system control unit that is implanted within the patient and that is configured to apply at least one stimulus to the target nerve within the patient in accordance with one or more stimulation parameters.
摘要翻译： 治疗患者的医疗状况的方法包括根据一个或多个刺激参数，用植入的系统控制单元对患者内的目标神经施加至少一种刺激。 目标神经可以包括源自患者的上颈椎区域的任何神经或源自患者的上颈椎区域的任何神经的分支。 用于治疗患者的医疗状况的系统包括植入患者体内的系统控制单元，其被配置为根据一个或多个刺激参数将至少一个刺激施加到患者内的目标神经。
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公开(公告)号：US08357145B2
公开(公告)日：2013-01-22
申请号：US11938740
申请日：2007-11-12
IPC分类号： B43L13/20
摘要： Systems and techniques for implanting medical devices. In one aspect, an apparatus includes a flexible base member that can be flexed manually to conform to a contour of an anatomy, the base member including a radioscopic indicium that has a characteristic such that, under radioscopic imaging, passage of a skin-penetrating electromagnetic radiation is hindered to an extent that is distinguishable from a hindrance of the electromagnetic radiation by another portion of the base member.
摘要翻译： 植入医疗器械的系统和技术。 在一个方面，一种装置包括柔性基部构件，其可以手动地弯曲以符合解剖结构的轮廓，所述基部构件包括放射线标记，所述放射线标记具有使得在放射线成像下穿透皮肤穿透电磁 辐射被阻碍到与基座部件的另一部分不同于电磁辐射的障碍的程度。
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23.发明授权公开(公告)号：US08244377B1
公开(公告)日：2012-08-14
申请号：US11863034
申请日：2007-09-27
IPC分类号： A61N1/05
CPC分类号： A61N1/0573 , A61N1/057
摘要： An implantable member has a body with a distal end portion and either a fixation portion of the body disposed near the distal end portion or a fixation device attached to a tip of the distal end portion of the body. The fixation portion can include at least one surface feature of the body that facilitates fixation of the implantable member within tissue when implanted.
摘要翻译： 可植入构件具有主体，其具有设置在远端部附近的远端部分和本体的固定部分，或固定装置附接到主体的远端部分的尖端。 固定部分可以包括主体的至少一个表面特征，其有助于植入时在植入组织内固定可植入构件。
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24.发明授权Methods and systems for stimulating a motor cortex of the brain to treat a medical condition 有权刺激大脑运动皮层治疗医疗状况的方法和系统公开(公告)号：US07962219B2
公开(公告)日：2011-06-14
申请号：US12685161
申请日：2010-01-11
IPC分类号： A61N1/36
CPC分类号： A61N1/36082 , A61N1/37205
摘要： Methods of treating a medical condition include applying at least one stimulus to a motor cortex within a brain of a patient with an implanted system control unit in accordance with one or more stimulation parameters. Systems for treating a medical condition include a system control unit implanted within the patient that is configured to apply at least one stimulus to a motor cortex within a brain of a patient in accordance with one or more stimulation parameters.
摘要翻译： 治疗医疗状况的方法包括根据一个或多个刺激参数，用植入的系统控制单元向患者的脑内的运动皮质施加至少一种刺激。 用于治疗医疗状况的系统包括植入患者体内的系统控制单元，其被配置为根据一个或多个刺激参数将至少一个刺激施加到患者脑内的运动皮质。
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25.发明申请METHODS AND SYSTEMS FOR STIMULATING A MOTOR CORTEX OF THE BRAIN TO TREAT A MEDICAL CONDITION 有权用于刺激脑的马齿苋治疗医疗条件的方法和系统公开(公告)号：US20100114192A1
公开(公告)日：2010-05-06
申请号：US12685161
申请日：2010-01-11
CPC分类号： A61N1/36082 , A61N1/37205
摘要： Methods of treating a medical condition include applying at least one stimulus to a motor cortex within a brain of a patient with an implanted system control unit in accordance with one or more stimulation parameters. Systems for treating a medical condition include a system control unit implanted within the patient that is configured to apply at least one stimulus to a motor cortex within a brain of a patient in accordance with one or more stimulation parameters.
摘要翻译： 治疗医疗状况的方法包括根据一个或多个刺激参数，用植入的系统控制单元向患者的脑内的运动皮质施加至少一种刺激。 用于治疗医疗状况的系统包括植入患者体内的系统控制单元，其被配置为根据一个或多个刺激参数将至少一个刺激施加到患者脑内的运动皮质。
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公开(公告)号：US20090192558A1
公开(公告)日：2009-07-30
申请号：US12358073
申请日：2009-01-22
申请人： Todd K. Whitehurst , Kristen N. Jaax , Rafael Carbunaru , Greg Baldwin , Brett Schleicher , Andrew DiGiore , Roger Hastings
发明人： Todd K. Whitehurst , Kristen N. Jaax , Rafael Carbunaru , Greg Baldwin , Brett Schleicher , Andrew DiGiore , Roger Hastings
IPC分类号： A61N1/34
CPC分类号： A61N1/36007 , A61N1/0551 , A61N1/36071 , A61N1/37205 , A61N1/37252
摘要： Methods and systems of treating a patient with pancreatitis pain include providing a stimulator, configuring one or more stimulation parameters to treat pancreatitis pain, programming the stimulator with the one or more stimulation parameters, generating a stimulus configured to treat pancreatitis pain with the stimulator in accordance with the one or more stimulation parameters, and applying the stimulus with the stimulator to one or more stimulation sites in accordance with the one or more stimulation parameters.
摘要翻译： 治疗患有胰腺炎疼痛的患者的方法和系统包括提供刺激器，配置一个或多个刺激参数以治疗胰腺炎疼痛，用所述一个或多个刺激参数编程所述刺激器，产生被配置为按照所述刺激器治疗胰腺炎疼痛的刺激 与所述一个或多个刺激参数相关联，并且根据所述一个或多个刺激参数将刺激器刺激施加到一个或多个刺激位点。
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27.发明授权Treatment of pathologic craving and aversion syndromes and eating disorders by electrical brain stimulation and/or drug infusion 有权通过电脑刺激和/或药物输注治疗病理性渴望和厌恶综合征和进食障碍公开(公告)号：US07493171B1
公开(公告)日：2009-02-17
申请号：US11140152
申请日：2005-05-27
IPC分类号： A61N1/00
CPC分类号： A61M5/14276 , A61M5/1723 , A61M2005/1726 , A61M2205/054 , A61M2205/3523 , A61M2205/50 , A61M2210/06 , A61M2210/0693 , A61N1/00 , A61N1/0531 , A61N1/0534 , A61N1/36082 , A61N1/36089
摘要： Systems and methods for introducing one or more stimulating drugs and/or applying electrical stimulation to the brain to at least treat or prevent obesity and/or other eating disorders, as well as drug, nicotine and alcohol addiction, uses at least one system control unit (SCU) producing electrical pulses delivered via electrodes implanted in the brain and/or producing drug infusion pulses, wherein the stimulating drug(s) are delivered to targeted areas in the brain.
摘要翻译： 用于将一种或多种刺激性药物引入和/或施加电刺激以至少治疗或预防肥胖症和/或其他进食障碍以及药物，尼古丁和酒精成瘾的系统和方法使用至少一个系统控制单元 （SCU）产生通过植入在脑中的电极递送的电脉冲和/或产生药物输注脉冲，其中刺激性药物被递送到脑中的目标区域。
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28.发明授权Systems and methods for treatment of diabetes by electrical brain stimulation and/or drug infusion 有权通过电脑刺激和/或药物输注治疗糖尿病的系统和方法公开(公告)号：US07440806B1
公开(公告)日：2008-10-21
申请号：US11140126
申请日：2005-05-27
IPC分类号： A61N1/00
CPC分类号： A61M5/1723 , A61M5/14276 , A61M5/172 , A61M2205/054 , A61M2205/3523 , A61M2205/3569 , A61M2210/0693 , A61N1/0529 , A61N1/0531 , A61N1/0534 , A61N1/08 , A61N1/36082 , A61N1/37205
摘要： Systems and methods for introducing one or more stimulating drugs and/or applying electrical stimulation to the brain to at least treat or prevent diabetes uses at least one system control unit (SCU) producing electrical pulses delivered via electrodes implanted in the brain and/or producing drug infusion pulses, wherein the stimulating drug(s) are delivered to targeted areas in the brain.
摘要翻译： 用于将一种或多种刺激性药物引入和/或施加电刺激以至少治疗或预防糖尿病的系统和方法使用至少一个系统控制单元（SCU），其产生通过植入脑内的电极递送的电脉冲和/或产生 药物输注脉冲，其中刺激性药物被递送到脑中的目标区域。
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29.发明授权Methods and systems of treating pancreatitis pain caused by sphincter of Oddi dysfunction 有权治疗由Oddi功能障碍括约肌引起的胰腺炎疼痛的方法和系统公开(公告)号：US08914112B2
公开(公告)日：2014-12-16
申请号：US12358002
申请日：2009-01-22
申请人： Todd K. Whitehurst , Rafael Carbunaru , Kristen N. Jaax , Andrew DiGiore , Brett Schleicher , Greg Baldwin , Roger Hastings
发明人： Todd K. Whitehurst , Rafael Carbunaru , Kristen N. Jaax , Andrew DiGiore , Brett Schleicher , Greg Baldwin , Roger Hastings
CPC分类号： A61N1/36007 , A61N1/36071 , A61N1/37205 , A61N1/37252
摘要： Methods and systems of treating a patient with pancreatitis pain include providing a stimulator, configuring one or more stimulation parameters to control sphincter of Oddi function, programming the stimulator with the one or more stimulation parameters, generating a stimulus configured to control sphincter of Oddi function with the stimulator in accordance with the one or more stimulation parameters, and applying the stimulus with the stimulator to one or more stimulation sites in accordance with the one or more stimulation parameters.
摘要翻译： 用于治疗患有胰腺炎疼痛的患者的方法和系统包括提供刺激器，配置一个或多个刺激参数以控制Oddi功能的括约肌，用所述一个或多个刺激参数编程所述刺激器，产生被配置为控制Oddi功能的括约肌的刺激， 所述刺激器根据所述一个或多个刺激参数，以及根据所述一个或多个刺激参数将刺激器刺激施加到一个或多个刺激部位。
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公开(公告)号：US08676322B2
公开(公告)日：2014-03-18
申请号：US12358073
申请日：2009-01-22
申请人： Todd K. Whitehurst , Kristen N. Jaax , Rafael Carbunaru , Greg Baldwin , Brett Schleicher , Andrew DiGiore , Roger Hastings
发明人： Todd K. Whitehurst , Kristen N. Jaax , Rafael Carbunaru , Greg Baldwin , Brett Schleicher , Andrew DiGiore , Roger Hastings
IPC分类号： A61N1/05
CPC分类号： A61N1/36007 , A61N1/0551 , A61N1/36071 , A61N1/37205 , A61N1/37252
摘要： Methods and systems of treating a patient with pancreatitis pain include providing a stimulator, configuring one or more stimulation parameters to treat pancreatitis pain, programming the stimulator with the one or more stimulation parameters, generating a stimulus configured to treat pancreatitis pain with the stimulator in accordance with the one or more stimulation parameters, and applying the stimulus with the stimulator to one or more stimulation sites in accordance with the one or more stimulation parameters.
摘要翻译： 治疗患有胰腺炎疼痛的患者的方法和系统包括提供刺激器，配置一个或多个刺激参数以治疗胰腺炎疼痛，用所述一个或多个刺激参数编程所述刺激器，产生被配置为按照所述刺激器治疗胰腺炎疼痛的刺激 与所述一个或多个刺激参数相关联，并且根据所述一个或多个刺激参数将刺激器刺激施加到一个或多个刺激位点。
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