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21.发明授权公开(公告)号：US08546126B2
公开(公告)日：2013-10-01
申请号：US12531030
申请日：2008-03-21
CPC分类号： C12N9/6483 , C07K14/37 , C12P21/02 , C12Y304/23004
摘要： The present teachings provide methods for increasing protein secretion, e.g., chymosin in filamentous fungi by co-expressing certain chaperone(s) and/or foldase(s). The present teachings also provide filamentous fungi containing certain chaperone(s) and/or foldase(s) and a protein of interest for increased secretion.
摘要翻译： 本教导提供了通过共同表达某些伴侣和/或折叠酶来增加蛋白质分泌的方法，例如丝状真菌中的凝乳酶。 本教导还提供含有某些伴侣和/或折叠酶的丝状真菌和用于增加分泌的目标蛋白质。
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公开(公告)号：US08236546B2
公开(公告)日：2012-08-07
申请号：US13092086
申请日：2011-04-21
CPC分类号： C12N9/2437 , C12P19/02 , C12P19/14 , C12Y302/01091
摘要： Disclosed are variants of Humicola grisea Cel7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted.
摘要翻译： 披露的是灰腐质霉Cel7A（CBH1.1），H.jecorina CBH1变体或嗜热链球菌CBH1的变体，编码它们的核酸及其生产方法。 变体纤维素酶具有7A族糖基水解酶的氨基酸序列，其中一个或多个氨基酸残基被取代。
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公开(公告)号：US08232080B2
公开(公告)日：2012-07-31
申请号：US13107702
申请日：2011-05-13
申请人： Anthony Day , Frits Goedegebuur , Peter Gualfetti , Colin Mitchinson , Paulien Neefe , Mats Sandgren , Andrew Shaw , Jerry Stahlberg
发明人： Anthony Day , Frits Goedegebuur , Peter Gualfetti , Colin Mitchinson , Paulien Neefe , Mats Sandgren , Andrew Shaw , Jerry Stahlberg
CPC分类号： C12N9/2437 , C11D3/38645 , C12P7/10 , C12P19/02 , C12P19/14 , C12Y302/01091 , D21C5/005 , Y02E50/16
摘要： Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility.
摘要翻译： 本文描述的是H.jecorina CBH I，Cel7酶的变体。 本发明提供了具有改善的热稳定性和可逆性的新型纤维二糖水解酶。
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公开(公告)号：US20120045811A1
公开(公告)日：2012-02-23
申请号：US13286955
申请日：2011-11-01
申请人： Nigel Dunn-Coleman , Frits Goedegebuur , Michael Ward , Jian Yao
发明人： Nigel Dunn-Coleman , Frits Goedegebuur , Michael Ward , Jian Yao
CPC分类号： C12N9/2437 , C11D3/38 , C11D3/38636 , C11D3/38645 , C12N9/2445 , C12N15/1137 , C12N2310/11 , C12P7/10 , C12P7/14 , C12P19/02 , C12P19/14 , C12P2201/00 , C12Y302/01004 , Y02E50/16 , Y02E50/17
摘要： The present invention provides a novel endoglucanase nucleic acid sequence, designated egl7, and the corresponding EGVII amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVII, recombinant EGVII proteins and methods for producing the same.
摘要翻译： 本发明提供了一种命名为egl7的新型内切葡聚糖酶核酸序列和相应的EGVII氨基酸序列。 本发明还提供了包含编码EGVII的核酸序列，重组EGVII蛋白的表达载体和宿主细胞及其制备方法。
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公开(公告)号：US20110229956A1
公开(公告)日：2011-09-22
申请号：US13107702
申请日：2011-05-13
申请人： Anthony Day , Frits Goedegebuur , Peter Gualfetti , Colin Mitchinson , Paulien Neefe , Mats Sandgren , Andrew Shaw , Jerry Stahlberg
发明人： Anthony Day , Frits Goedegebuur , Peter Gualfetti , Colin Mitchinson , Paulien Neefe , Mats Sandgren , Andrew Shaw , Jerry Stahlberg
CPC分类号： C12N9/2437 , C11D3/38645 , C12P7/10 , C12P19/02 , C12P19/14 , C12Y302/01091 , D21C5/005 , Y02E50/16
摘要： Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility.
摘要翻译： 本文描述的是H.jecorina CBH I，Cel7酶的变体。 本发明提供了具有改善的热稳定性和可逆性的新型纤维二糖水解酶。
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公开(公告)号：US07960146B2
公开(公告)日：2011-06-14
申请号：US11893925
申请日：2007-08-17
申请人： Nigel Dunn-Coleman , Frits Goedegebuur , Michael Ward , Jian Yao
发明人： Nigel Dunn-Coleman , Frits Goedegebuur , Michael Ward , Jian Yao
CPC分类号： A21D8/042 , C11D3/38645 , C12N9/2445 , C12N15/1137 , C12Y302/01021 , Y02E50/17
摘要： The present invention provides a novel β-glucosidase nucleic acid sequence, designated bgl3, and the corresponding BGL3 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL3, recombinant BGL3 proteins and methods for producing the same.
摘要翻译： 本发明提供了一种命名为bgl3和相应的BGL3氨基酸序列的新颖的 - 葡糖苷酶核酸序列。 本发明还提供了包含编码BGL3的核酸序列，重组BGL3蛋白的表达载体和宿主细胞及其制备方法。
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公开(公告)号：US07811799B2
公开(公告)日：2010-10-12
申请号：US11329621
申请日：2006-01-10
申请人： Nigel Dunn-Coleman , Frits Goedegebuur , Michael Ward , Jian Yao
发明人： Nigel Dunn-Coleman , Frits Goedegebuur , Michael Ward , Jian Yao
CPC分类号： C12N9/2437 , C11D3/38 , C11D3/38636 , C12Y302/01004 , Y02E50/16 , Y02E50/17
摘要： The present invention provides a novel endoglucanase nucleic acid sequence, designated egl6, and the corresponding EGVI amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVI, recombinant EGVI proteins and methods for producing the same.
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公开(公告)号：US20100203593A1
公开(公告)日：2010-08-12
申请号：US12683108
申请日：2010-01-06
CPC分类号： C07K14/37 , C11D3/38645 , C12N9/18 , C12Y302/01004 , C12Y302/01091 , Y02E50/16
摘要： Described herein are novel gene sequences isolated from Trichoderma reesei. Two genes encoding proteins comprising a cellulose binding domain, one encoding an arabionfuranosidase and one encoding an acetylxylanesterase are described. The sequences, CIP1 and CIP2, contain a cellulose binding domain. These proteins are especially useful in the textile and detergent industry and in pulp and paper industry.
摘要翻译： 本文描述了从里氏木霉分离的新基因序列。 描述编码包含纤维素结合结构域的蛋白质的两个基因，一个编码阿拉伯糖呋喃糖苷酶的基因和一个编码乙酰木聚糖酯酶的基因。 序列CIP1和CIP2包含纤维素结合结构域。 这些蛋白质在纺织和洗涤剂行业以及纸浆和造纸工业中特别有用。
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公开(公告)号：US20080095889A1
公开(公告)日：2008-04-24
申请号：US11893925
申请日：2007-08-17
申请人： Nigel Dunn-Coleman , Frits Goedegebuur , Michael Ward , Jian Yao
发明人： Nigel Dunn-Coleman , Frits Goedegebuur , Michael Ward , Jian Yao
IPC分类号： A21D2/08 , C11D3/33 , C12N1/20 , C12N15/00 , C12N15/11 , C12N5/04 , C12N5/06 , C12N9/24 , C12P21/04
CPC分类号： A21D8/042 , C11D3/38645 , C12N9/2445 , C12N15/1137 , C12Y302/01021 , Y02E50/17
摘要： The present invention provides a novel β-glucosidase nucleic acid sequence, designated bgl3, and the corresponding BGL3 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL3, recombinant BGL3 proteins and methods for producing the same.
摘要翻译： 本发明提供了命名为bgl3的新型β-葡糖苷酶核酸序列和相应的BGL3氨基酸序列。 本发明还提供了包含编码BGL3的核酸序列，重组BGL3蛋白的表达载体和宿主细胞及其制备方法。
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公开(公告)号：US07351573B2
公开(公告)日：2008-04-01
申请号：US11046300
申请日：2005-01-27
申请人： Nigel Dunn-Coleman , Frits Goedegebuur , Michael Ward , Jian Yao
发明人： Nigel Dunn-Coleman , Frits Goedegebuur , Michael Ward , Jian Yao
CPC分类号： A21D8/042 , C11D3/38645 , C12N9/2445 , C12N15/1137 , C12Y302/01021 , Y02E50/17
摘要： The present invention provides a novel β-glucosidase nucleic acid sequence, designated bgl3, and the corresponding BGL3 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL3, recombinant BGL3 proteins and methods for producing the same.
摘要翻译： 本发明提供了命名为bgl3的新型β-葡糖苷酶核酸序列和相应的BGL3氨基酸序列。 本发明还提供了包含编码BGL3的核酸序列，重组BGL3蛋白的表达载体和宿主细胞及其制备方法。
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