摘要:
A medical device comprising a medical device body having drug-loaded vesicles thereon. The vesicles are ultrasound sensitive and release the drug upon ultrasound stimulation. Also provided is a method for controlling drug release from a medical device using drug-loaded vesicles that are ultrasound sensitive.
摘要:
In general, embodiments of the present invention provide a DR solution for a networked computing environment such as a cloud computing environment. Specifically, a customer or the like can select a disaster recovery provider from a pool (at least one) of disaster recovery providers using a customer interface to a DR portal. Similarly, using the interface and DR portal, the customer can then submit a request for DR to be performed for a set (at least one) of applications. The customer will then also submit (via the interface and DR portal) DR information. This information can include, among other things, a set of application images, a set of application files, a set of recovery requirements, a designation of one or more specific (e.g., application) components for which DR is desired, dump file(s), database file(s), etc. Using the DR information, the DR provider will then generate and conduct a set of DR tests and provide the results to the customer via the DR portal and interface. In one embodiment, a temporary DR environment can be created (e.g., by the DR provider or the customer) in which the DR tests are conducted.
摘要:
Embodiments of the present invention provide an approach for locating connections/contacts of a user of social networking websites based on an intended travel destination of the user. Specifically, embodiments of the present invention will analyze a set of online resources (e.g., travel websites, social networking services, calendaring programs, etc.) to identify one or more travel profiles (e.g., reservations) associated with the user. Based on one or more intended destinations set forth in the travel profile(s), social networking websites associated with the user may be analyzed to identify and locate contacts/connections of the user that are located within a predetermined proximity of the intended destination(s). Once such contacts have been identified, the user may be provided with a notification that identifies the contact and provides the contact's location.
摘要:
A method includes: providing a tubular substrate in a chamber, the tubular substrate having a lumen, an a luminal surface and a luminal surface; providing a target in the lumen; depositing a first coating onto the abluminal surface and a second coating onto the luminal surface while keeping the tubular substrate in the chamber. An endoprosthesis, such as a stent, including a first coating on at least one portion of its abluminal surface and a second coating on at least one portion of its luminal surface is also disclosed.
摘要:
In general, embodiments of the present invention provide a DR solution for a networked computing environment such as a cloud computing environment. Specifically, a customer or the like can select a disaster recovery provider from a pool (at least one) of disaster recovery providers using a customer interface to a DR portal. Similarly, using the interface and DR portal, the customer can then submit a request for DR to be performed for a set (at least one) of applications. The customer will then also submit (via the interface and DR portal) DR information. This information can include, among other things, a set of application images, a set of application files, a set of recovery requirements, a designation of one or more specific (e.g., application) components for which DR is desired, dump file(s), database file(s), etc. Using the DR information, the DR provider will then generate and conduct a set of DR tests and provide the results to the customer via the DR portal and interface. In one embodiment, a temporary DR environment can be created (e.g., by the DR provider or the customer) in which the DR tests are conducted.
摘要:
Endoprostheses include an endoprosthesis wall that includes a surface layer that includes a metallic material and that defines a plurality of discrete pores. A porous material is disposed in one or more pores of the surface layer. The endoprostheses can, for example, deliver a therapeutic agent, such as a drug, in a controlled manner over an extended period of time.
摘要:
A method and system for leveraging content is provided. The method includes receiving, data associated with a subscriber and registering the subscriber with an ECM computing system. Devices belonging to the subscriber are connected to the ECM computing system and metadata associated with content retrieved from the devices is generated. The content in the devices are classified into formal content and informal content. Multiple searches for additional content are monitored and multifaceted search results associated with the formal content and the informal content are generated and presented to the subscriber. The subscriber has an option to request informal content on additional end user devices from respective end users based on metadata presented by search results.
摘要:
The attached disclosure provides a systems approach based on mathematical modelling of the kinetics of essential biochemical pathways involved in organ homeostasis. When this in silico model is coupled with in-vitro and/or in-vivo measurements to quantify drug-induced perturbations, a powerful platform that allows accurate and mechanistic-level prediction of drug-induced organ injury can be generated. The method described in this disclosure demonstrates that several physiological situations can also be accurately modelled in addition to the effect of perturbations induced by drugs. It can also be used along with high-throughput “omics” data to generate testable hypotheses leading to informed decision-making in drug development.
摘要:
Service data and service management data traffic in a networked computing environment (e.g., a cloud computing environment) may flow thorough a large number of devices (e.g., storage, network, cache and other devices and appliances) when the data move from one or more source systems to one or more target systems (or end user systems). Embodiments of the present invention provide a data analysis driven approach that detects patterns in data movements, and data traffic can be used to determine placement of certain network service components such as, among others, storage devices and appliances, server devices and appliances, network devices and appliances, etc.