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21.发明授权System for connecting a compatibility liner with a source of perishable therapeutic 失效将兼容性衬垫与易腐食品来源连接的系统公开(公告)号：US07407497B2
公开(公告)日：2008-08-05
申请号：US11433584
申请日：2006-05-15
IPC分类号： A61M25/00
CPC分类号： A61M39/12 , A61M5/142 , A61M25/0097
摘要： A system for connecting a compatibility liner with a source of perishable therapeutic is provided. In one exemplary system for connecting a reservoir of perishable therapeutic with a lumen, a hollow hub having a first end and a second end is provided. The first end of the hollow hub, which contains a bond port, is in fluid communication with the second end. The second end of the hollow hub may contain a docking groove that is sized to couple a reservoir to it. The system also includes an inner hypo-tube having a proximal tip and an inner lumen. This inner lumen is lined with a therapeutic compatible lining and is in fluid communication with the second end of the hub through the proximal tip of the inner hypo-tube. The inner lining and the proximal tip in this system are configured to shield therapeutic ejected from the reservoir from contacting materials that can diminish the integrity of the therapeutic.
摘要翻译： 提供了一种用于将兼容性衬垫与易腐食品治疗源连接的系统。 在用于将易腐烂治疗剂的储存器与管腔连接的一个示例性系统中，提供了具有第一端和第二端的中空毂。 包含接合端口的中空毂的第一端与第二端流体连通。 中空轮毂的第二端可以包含一个对接凹槽，其尺寸设置成将储存器连接到其上。 该系统还包括具有近端和内腔的内管。 该内腔内衬有治疗相容的内衬，并通过内管的近端与流体通过毂的第二端流体连通。 该系统中的内衬和近侧尖端构造成屏蔽从储存器喷出的治疗物质可能会降低治疗剂完整性的接触材料。
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22.发明授权Apparatus for connecting a compatibility liner with a source of perishable therapeutic 失效用于将兼容性衬垫与易腐食品治疗源连接的装置公开(公告)号：US06530912B2
公开(公告)日：2003-03-11
申请号：US09758129
申请日：2001-01-12
IPC分类号： A61M2500
CPC分类号： A61M39/12 , A61M5/142 , A61M25/0097
摘要： An apparatus for connecting a compatibility liner with a source of perishable therapeutic is provided. In one exemplary system for connecting a reservoir of perishable therapeutic with a lumen, a hollow hub having a first end and a second end is provided. The first end of the hollow hub, which contains a bond port, is in fluid communication with the second end. The second end of the hollow hub may contain a docking groove that is sized to couple a reservoir to it. The system also includes an inner hypo-tube having a proximal tip and an inner lumen. This inner lumen is lined with a therapeutic compatible lining and is in fluid communication with the second end of the hub through the proximal tip of the inner hypo-tube. The inner lining and the proximal tip in this system are configured to shield therapeutic ejected from the reservoir from contacting materials that can diminish the integrity of the therapeutic.
摘要翻译： 提供了一种用于将兼容性衬垫与易腐食品治疗源连接的装置。 在用于将易腐烂治疗剂的储存器与管腔连接的一个示例性系统中，提供了具有第一端和第二端的中空毂。 包含接合端口的中空毂的第一端与第二端流体连通。 中空轮毂的第二端可以包含一个对接凹槽，其尺寸设置成将储存器连接到其上。 该系统还包括具有近端和内腔的内管。 该内腔内衬有治疗相容的内衬，并通过内管的近端与流体通过毂的第二端流体连通。 该系统中的内衬和近侧尖端构造成屏蔽从储存器喷出的治疗物质可能会降低治疗剂完整性的接触材料。
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公开(公告)号：US10314570B2
公开(公告)日：2019-06-11
申请号：US14343843
申请日：2012-09-10
摘要： Various surgical tissue anchor retention mechanisms, systems and methods are provided. The mechanisms, systems and methods can include a delivery tool or needle having a flex joint, a snap-fit, a cam and follower, a rotating tip, an expandable lock, a coil, an inverted collet, a tab, a buckling tube, an inflation element or like anchor retention or securement features.
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公开(公告)号：US20160296705A1
公开(公告)日：2016-10-13
申请号：US15180495
申请日：2016-06-13
CPC分类号： A61M5/3007 , A61B1/018 , A61B90/39 , A61B2090/3925 , A61B2090/3966 , A61M5/30 , A61M5/315 , A61M25/005 , A61M25/0054 , A61M25/007 , A61M25/04 , A61M31/00 , A61M2205/502 , A61M2210/1078
摘要： A needleless fluid injection device including a flexible shaft with a proximal end, a distal end, an injection lumen extending from the proximal end to the distal end of the shaft, and at least one injection orifice extending through a wall of the injection lumen at the distal end of the shaft. The injection lumen can include a depth-limiting system (462) at its distal end for controlling the depth of insertion of the injection lumen relative to a target tissue of a patient. The injection lumen can alternatively or additionally include at least one guidance feature. The injection lumen can alternatively or additionally include at least one flow-modifying protrusion extending from the inner tubular wall of the injection lumen and toward a longitudinal axis of the injection lumen.
摘要翻译： 一种无针流体注射装置，包括具有近端的柔性轴，远端，从所述轴的近端延伸到所述远端的注射腔，以及在所述注射腔的壁处延伸穿过所述注射腔的壁的至少一个注射孔 轴的远端。 注射内腔在其远端可以包括深度限制系统（462），用于控制注射内腔相对于患者的目标组织的插入深度。 注射腔可以替代地或另外包括至少一个引导特征。 注射腔可以可选地或另外包括至少一个从注射腔的内管壁延伸并且朝向注射腔的纵向轴线延伸的流动改变突出部。
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公开(公告)号：US09370646B2
公开(公告)日：2016-06-21
申请号：US13133091
申请日：2009-12-04
CPC分类号： A61M5/3007 , A61M5/204 , A61M5/30 , A61M5/31553 , A61M5/31581 , A61M5/425 , A61M25/10 , A61M25/1018 , A61M25/10182 , A61M25/10185 , A61M39/12 , A61M2005/3152 , A61M2210/1078
摘要： In one aspect of this invention, control systems (100) are provided for controlling the inflation of a tissue tensioner or balloon for a fluid delivery system, such as for a needleless fluid injection device. In another aspect of the invention, a system for reducing the response time for jet injection of fluid is provided (200). In yet another aspect of the invention, systems and devices are provided for controlling the volume of fluid that is ejected from a fluid injection system, which systems include at least one stop (410) that is selectively rotated to limit the movement of a shaft (402) in a linear direction, thereby controlling the amount of fluid that is ejected from the system.
摘要翻译： 在本发明的一个方面，提供了控制系统（100），用于控制用于流体输送系统的组织张紧器或气囊的膨胀，例如用于无针注射流体注射装置。 在本发明的另一方面，提供了一种用于减少喷射流体的响应时间的系统（200）。 在本发明的另一方面，提供了用于控制从流体注射系统喷射的流体体积的系统和装置，该系统包括至少一个选择性地旋转以限制轴的运动的止挡件（410） 402），从而控制从系统喷出的流体的量。
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公开(公告)号：US08852084B2
公开(公告)日：2014-10-07
申请号：US13168565
申请日：2011-06-24
申请人： Justin M. Crank
发明人： Justin M. Crank
CPC分类号： A61B1/018 , A61B1/00091 , A61B1/00101 , A61B1/00131 , A61B1/307 , Y10T29/49826
摘要： An endoscope adapter ring for a needleless fluid delivery system for delivering therapeutic fluids to treatment sites within a patient. The needless fluid delivery system can include an automated injector source and a needleless access device. The access device can include a delivery scope and a treatment specific applicator. The adapter ring is operably attached to the endoscope to keep the injector lumen in a known orientation for the use of a side injector.
摘要翻译： 一种用于将治疗性流体递送到患者体内的治疗部位的无针流体输送系统的内窥镜适配器环。 不需要的流体输送系统可以包括自动注射器源和无针入口装置。 进入装置可以包括输送范围和治疗特定的施用器。 适配器环可操作地附接到内窥镜以将注射器内腔保持在已知方向以使用侧注射器。
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27.发明申请公开(公告)号：US20110282318A1
公开(公告)日：2011-11-17
申请号：US13133119
申请日：2009-12-04
申请人： Justin M. Crank , Kathryn Bertelson
发明人： Justin M. Crank , Kathryn Bertelson
IPC分类号： A61M5/307
CPC分类号： A61M5/30 , A61M5/3291 , A61M25/00 , A61M25/007 , A61M39/12 , A61M2039/1027 , A61M2210/1078 , A61M2210/1082 , A61M2210/1085 , A61M2210/1089
摘要： Described are devices useful to inject fluid to tissue without the use of a needle, and related methods; the devices include one or a combination of features such as ejection orifices (40), distal end control features, or combinations of these; the systems can include a fluid delivery system having an injector source and an access device; the access device can comprise a minimally invasive, tubular delivery lumen (34) such as a catheter or endoscope; the tube-like device further includes one or more apposing jets that are selectively fired to force the injection orifice of the tube-like device against the target tissue; selective firing can include a continuous firing during the injection to improve the efficiency of the treatment.
摘要翻译： 描述了可用于将液体注入组织而不使用针的装置及相关方法; 这些装置包括一个或诸如喷射孔（40），远端控制特征或它们的组合的特征的组合; 该系统可以包括具有喷射源和进入装置的流体输送系统; 进入装置可以包括诸如导管或内窥镜的微创管状递送腔（34）; 管状装置还包括一个或多个喷射装置，其被选择性地烧制以迫使管状装置的喷射孔抵靠靶组织; 选择性烧制可包括注射期间的连续烧制以提高治疗效率。
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公开(公告)号：US20110172631A1
公开(公告)日：2011-07-14
申请号：US12839956
申请日：2010-07-20
申请人： Justin M. Crank
发明人： Justin M. Crank
CPC分类号： A61M5/31586 , A61B1/015 , A61M5/1452 , A61M5/204 , A61M5/30 , A61M5/3007 , A61M5/31501 , A61M5/31553 , A61M5/3156 , A61M5/31563 , A61M2205/505
摘要： A high-pressure fluid injection system, which includes a rechargeable injection chamber with a proximal end, a distal end, and an internal opening extending from the proximal end to the distal end, a plunger slideably engaged with the internal opening of the injection chamber, an injection tube extending from the distal end of the injection chamber and in fluidic communication with the internal opening of the injection chamber, and a check valve between the proximal and distal ends of the injection chamber. The internal opening includes a high-pressure zone adjacent to the check valve and having a first diameter, and a low-pressure zone proximal to the high-pressure zone and having a second diameter that is larger than the first diameter.
摘要翻译： 一种高压流体注射系统，其包括具有近端，远端和从近端延伸到远端的内部开口的可再充电注射室，与所述注射室的内部开口可滑动地接合的柱塞， 注射管，其从注射室的远端延伸并与注射室的内部开口流体连通;以及在注射室的近端和远端之间的止回阀。 内部开口包括邻近止回阀并具有第一直径的高压区和靠近高压区的低压区，并具有大于第一直径的第二直径。
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29.发明申请公开(公告)号：US20090312696A1
公开(公告)日：2009-12-17
申请号：US12087231
申请日：2006-12-28
CPC分类号： A61M25/0074 , A61M25/0068 , A61M25/007 , A61M25/0071 , A61M25/0082 , A61M25/0084 , A61M25/01 , A61M25/0136 , A61M2025/0073 , A61M2025/0087 , A61M2025/0096 , A61M2210/1089 , A61M2210/166
摘要： Described are devices useful to deliver fluid to tissue of the bladder, bladder neck, prostate, urethra, ureter, kidney, and related methods, the devices including one or a combination of features such as a steerable shaft, an optical mechanism, multiple fluid delivery orifices that may be moveable or extendable laterally, longitudinally, or distally; the methods allowing for delivery of one or multiple types of fluid to tissue such as the bladder (including the bladder neck), urethra, prostate, kidney, ureter, etc.
摘要翻译： 描述了可用于将流体输送到膀胱，膀胱颈，前列腺，尿道，输尿管，肾脏和相关方法的组织的装置，该装置包括一个或组合的特征，例如可转向轴，光学机构，多个流体递送 可横向，纵向或远端可移动或延伸的孔; 允许将一种或多种类型的流体递送到诸如膀胱（包括膀胱颈），尿道，前列腺，肾脏，输尿管等组织的方法。
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公开(公告)号：US09572648B2
公开(公告)日：2017-02-21
申请号：US13334002
申请日：2011-12-21
申请人： Justin M. Crank , Kathryn A. Bertelson , Patricia M. Derus , Gary A. Rocheleau , Michael A. Knipfer
发明人： Justin M. Crank , Kathryn A. Bertelson , Patricia M. Derus , Gary A. Rocheleau , Michael A. Knipfer
CPC分类号： A61F2/0045 , A61B17/0401 , A61B17/0483 , A61B17/06109 , A61B17/2812 , A61B2017/0042 , A61B2017/00867 , A61B2017/0417 , A61B2017/0427 , A61B2017/0437 , A61B2017/0461
摘要： Various embodiments of a mesh or implant systems are provided. The implants can include one or more anchors, arms and the like. The anchors can include hingeable or patterned finger extension to facilitate tissue penetration and retention. Various tensioning and adjustment mechanisms, devices and methods are further provided for the implant systems.
摘要翻译： 提供了网格或植入物系统的各种实施例。 植入物可以包括一个或多个锚，臂等。 锚固件可以包括可铰链或图案化的手指延伸以便于组织穿透和保留。 进一步为植入系统提供各种张紧和调节机构，装置和方法。
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