公开(公告)号：US10980727B2

公开(公告)日：2021-04-20

申请号：US16324166

申请日：2016-08-09

Applicant: SYMRISE AG

Inventor： Benoit Join ,  Michael Backes ,  Arnold Machinek ,  Ulrike Simchen ,  Jenny Weissbrodt ,  Jens Fahle

IPC: A61K8/42 ,  A61K8/92 ,  A61K8/34 ,  A61K8/37 ,  A61Q5/02 ,  A61Q19/10 ,  A61Q19/00

Abstract: Mixtures comprising a selected cooling active ingredient (E)-3-benzo[1,3]dioxol-5-yl-N,N-diphenyl-2-propenamide and at least one other substance which acts as a solvent for (E)-3-benzo[1,3]dioxol-5-yl-N,N-diphenyl-2-propenamide, wherein the substance is selected form the group consisting of benzyl benzoate, diethyl succinate, triethyl citrate, triacetin, ethanol, peppermint oil, anethol, optamint, propylene glycol, further cooling active ingredients or mixtures thereof.

公开(公告)号：US10767198B2

公开(公告)日：2020-09-08

申请号：US15779214

申请日：2015-11-28

Applicant: SYMRISE AG

Inventor： Marco A. Fraatz ,  Holger Zorn ,  Johanna Rost ,  Michael Goldmann ,  Egon Gross ,  Jakob Ley ,  Katrin Geissler ,  Torsten Geissler ,  Michael Backes ,  Fabia Hentschel ,  Jens-Michael Hilmer

IPC: C12P7/24 ,  C07C45/27 ,  C12N9/02

Abstract: A method for producing branched aldehydes is proposed, the method comprising the following steps: (a) providing a culture of one or more fungi of the genus Conidiobolus and producing biomass containing branched carboxylic acids in free and/or bound form; (b) extracting the biomass from step (a) to produce a first intermediate containing free and/or bound carboxylic acids; (c) optionally chemically, enzymatically or microbially hydrolyzing the bound carboxylic acids from the first intermediate; (d) treating the first intermediate with a reducing agent of a chemical nature to convert the free and/or bound carboxylic acids into the corresponding alcohols and optionally separating one or more alcohols from interfering by-products and producing the chemically produced second intermediate containing these alcohols as a mixture or in enriched form; (e) treating the first intermediate with a reducing agent of a biological nature to convert the free and/or bound carboxylic acids into the corresponding aldehydes having the same number of carbon atoms compared to the free and/or bound carboxylic acids or into the corresponding aldehydes having a reduced number of carbon atoms by one compared to the free and/or bound carboxylic acids and producing the biologically produced second intermediate containing these aldehydes; (f) treating the chemically produced second intermediate with an oxidizing agent of a chemical nature to convert the free and/or bound alcohols into the corresponding aldehydes; and optionally (g) removing interfering by-components from the fractions obtainable after step(s) (d) and/or (e) and/or (f).

公开(公告)号：US10702484B2

公开(公告)日：2020-07-07

申请号：US16071295

申请日：2016-04-28

Applicant: SYMRISE AG

Inventor： Gerhard Krammer ,  Jakob Ley ,  Fabia Hentschel ,  Susanne Paetz ,  Thomas Riess ,  Michael Backes

IPC: A61K31/12 ,  A23L27/00 ,  A23L27/26 ,  A23L27/30 ,  A23L27/60 ,  A23L27/20 ,  A23G3/38 ,  A23G4/06 ,  A23L2/56 ,  A23L2/60

Abstract: The present invention concerns the use of 3-(3-Hydroxy-4-methoxy-phenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one for masking, reducing or suppressing an unpleasant taste impression, preferably bitter, sour and/or astringent taste impression of unpleasant-tasting substances or mixture of substances, preferably bitter-, sour-, and/or astringent-tasting substances or mixtures of substances, and in particular the bitter taste impression of bitter-tasting substances, and/or modulating the taste impressions selected from the group consisting of cooling, umami, fruity and spicy notes of cooling-, umami-, fruity- or spicy-tasting substances or mixture of substances, and simultaneously intensifying the sweet-taste impression of sweet-tasting substances or mixtures of substances or both sweet- and bitter-tasting tasting substances or mixture of substances.

公开(公告)号：US09894921B2

公开(公告)日：2018-02-20

申请号：US14436599

申请日：2013-12-02

Applicant: SYMRISE AG

Inventor： Michael Backes ,  Jakob Peter Ley ,  Susanne Paetz ,  Katharina Reichelt

IPC: A23L1/22 ,  A23L1/226 ,  A23L27/00 ,  A23L27/20 ,  A23L27/23 ,  A23L27/26

CPC classification number: A23L27/204 ,  A23L27/23 ,  A23L27/26 ,  A23L27/88

Abstract: Proposed is the use of cinnamic acid amide derivatives of formula (I) in which R1, R2, R3 and R4, independently of one another, stand for hydrogen or a methoxy group, as a flavouring.