公开(公告)号：US20080242397A1

公开(公告)日：2008-10-02

申请号：US11692666

申请日：2007-03-28

申请人： William Scott ,  Nicholas Koenig

发明人： William Scott ,  Nicholas Koenig

IPC分类号： A63F13/06

CPC分类号： G07F17/3206 ,  G07F17/3209

摘要： Provided in embodiments of the present invention is a gaming device with a player interaction mechanism included in a gaming machine handle. In one embodiment, a gaming device operable by a player includes a gaming cabinet housing a processor to operate gaming sessions on the gaming device and having a display to visually represent the outcome of the gaming session. The gaming device also includes a first player interaction mechanism arranged on the gaming cabinet, a gaming handle attached to the gaming cabinet, and a second player interaction mechanism located on the gaming handle.

摘要翻译： 在本发明的实施例中提供的是具有包括在游戏机手柄中的玩家交互机制的游戏装置。 在一个实施例中，由玩家操作的游戏装置包括容纳处理器的游戏柜，用于在游戏装置上操作游戏会话，并具有可视地表示游戏会话的结果的显示器。 游戏装置还包括布置在游戏机上的第一玩家交互机构，连接到游戏机的游戏手柄以及位于游戏手柄上的第二玩家交互机构。

公开(公告)号：US20060223761A1

公开(公告)日：2006-10-05

申请号：US10768970

申请日：2004-02-02

申请人： James Audia ,  Thomas Britton ,  James Droste ,  Beverly Folmer ,  George Huffman ,  Varghese John ,  Lee Latimer ,  Thomas Mabry ,  Jeffrey Nissen ,  Warren Porter ,  Jon Reel ,  Eugene Thorsett ,  Jay Tung ,  Jing Wu ,  Clark Eid ,  William Scott

发明人： James Audia ,  Thomas Britton ,  James Droste ,  Beverly Folmer ,  George Huffman ,  Varghese John ,  Lee Latimer ,  Thomas Mabry ,  Jeffrey Nissen ,  Warren Porter ,  Jon Reel ,  Eugene Thorsett ,  Jay Tung ,  Jing Wu ,  Clark Eid ,  William Scott

IPC分类号： A61K38/04 ,  A61K31/47 ,  A61K31/405 ,  A61K31/4015 ,  A61K31/445

CPC分类号： C07K5/06191 ,  A61K31/00 ,  A61K31/4015 ,  A61K31/405 ,  A61K31/445 ,  A61K31/47 ,  A61K38/05 ,  A61K38/06 ,  C07K5/06078

摘要： Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease Also disclosed pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

摘要翻译： 公开了抑制β-淀粉样蛋白肽释放和/或其合成，因此具有治疗阿尔茨海默病的效用的化合物。还公开了包含抑制β-淀粉样蛋白肽释放和/或其合成的化合物的药物组合物，以及 用这种药物组合物预防性和治疗性地治疗阿尔茨海默病。

公开(公告)号：US20050210742A1

公开(公告)日：2005-09-29

申请号：US11028504

申请日：2005-01-04

申请人： Stephen Carr ,  Angelo Loi ,  William Scott

发明人： Stephen Carr ,  Angelo Loi ,  William Scott

IPC分类号： A01C1/06 ,  C05F11/08

CPC分类号： C05F11/08

摘要： The present invention relates to a delivery system for the administration of microorganisms, the delivery system including at least one species of micro-organisms, water and an aluminosilicate clay and a method for its preparation and use. The delivery system of the present invention is in part intended to provide an inoculant composition for the inoculant of legumes to stimulate root nodule formation and allow improved capacity for storage prior to use.

摘要翻译： 本发明涉及用于施用微生物的递送系统，包括至少一种微生物，水和硅铝酸盐粘土的递送系统及其制备和使用方法。 本发明的递送系统部分旨在提供用于刺激根瘤结构的豆类接种物的孕育剂组合物，并且在使用之前允许改善储存容量。

公开(公告)号：US20050203080A1

公开(公告)日：2005-09-15

申请号：US10733877

申请日：2003-12-12

申请人： Jing Wu ,  Jay Tung ,  Eugene Thorsett ,  Michael Pleiss ,  Jeffrey Nissen ,  R. Neitz ,  Lee Latimer ,  Varghese John ,  Stephen Freedman ,  Thomas Britton ,  James Audia ,  Jon Reel ,  Thomas Mabry ,  Bruce Dressman ,  Cynthia Cwi ,  James Droste ,  Steven Henry ,  Stacey McDaniel ,  William Scott ,  Russell Stucky ,  Warren Porter

发明人： Jing Wu ,  Jay Tung ,  Eugene Thorsett ,  Michael Pleiss ,  Jeffrey Nissen ,  R. Neitz ,  Lee Latimer ,  Varghese John ,  Stephen Freedman ,  Thomas Britton ,  James Audia ,  Jon Reel ,  Thomas Mabry ,  Bruce Dressman ,  Cynthia Cwi ,  James Droste ,  Steven Henry ,  Stacey McDaniel ,  William Scott ,  Russell Stucky ,  Warren Porter

IPC分类号： A61K31/40 ,  A61K31/4015 ,  A61K31/445 ,  A61K31/55 ,  A61K38/04 ,  A61K38/05 ,  A61P25/28 ,  C07D223/18 ,  C07D471/04 ,  C07D471/06 ,  C07D471/08

CPC分类号： C07D471/04 ,  A61K31/40 ,  A61K31/4015 ,  A61K31/445 ,  A61K31/5513 ,  A61K38/05 ,  C07C237/22 ,  C07C2603/32 ,  C07D223/18 ,  C07D307/33 ,  C07D311/76 ,  C07D471/06 ,  C07D471/08

摘要： Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

公开(公告)号：US20230363974A1

公开(公告)日：2023-11-16

申请号：US18220664

申请日：2023-07-11

申请人： William Scott

发明人： William Scott

IPC分类号： A61H3/02

CPC分类号： A61H3/02 ,  A61H3/0288 ,  A61H2201/1635 ,  A61H2003/0238

摘要： A mobility aid in the form of a cuff crutch can be used in various configurations. The cuff crutch includes an arm cuff positioned at a distal end of a tube that is adjustably positioned into a main tube of the crutch. The main tube may be bent at an angle in a position below a mid-point thereof, that is, the bend is closer to the foot end of the main tube as opposed to the cuff end thereof. A foot tube may be adjustably positioned into the foot end of the main tube and a foot may be disposed on a distal end of the foot tube. By providing the various adjustments, the cuff crutch may be used as a cuff cane, a cuff crutch or a walking stick, as discussed herein. The cuff, grip, and foot may include designs that offer various improvements over conventional mobility aids.

公开(公告)号：USD815814S1

公开(公告)日：2018-04-24

申请号：US29572295

申请日：2016-07-26

申请人： William Scott

设计人： William Scott

公开(公告)号：US09782472B2

公开(公告)日：2017-10-10

申请号：US13079472

申请日：2011-04-04

申请人： Phillip Berman ,  Sara O'Rourke ,  William Scott

发明人： Phillip Berman ,  Sara O'Rourke ,  William Scott

IPC分类号： C07K14/005 ,  A61K38/16 ,  C07K14/00 ,  C07H21/04 ,  C07K14/47 ,  A61K39/21 ,  G01N33/569 ,  A61K39/12

CPC分类号： A61K39/21 ,  A61K38/162 ,  A61K39/12 ,  C07K14/005 ,  C12N2740/15022 ,  C12N2740/16122 ,  C12N2740/16134 ,  G01N33/56988 ,  G01N2333/162 ,  G01N2500/02

摘要： Therapeutic compositions and methods for treating HIV including identification and manipulation of particular domains associated with immunogenicity.

公开(公告)号：US20130210815A1

公开(公告)日：2013-08-15

申请号：US13700956

申请日：2011-05-27

申请人： Ulrich Klar ,  Marcus Koppitz ,  Rolf Jautelat ,  Dirk Kosemund ,  Rolf Bohlmann ,  Benjamin Bader ,  Philip Lienau ,  Gerhard Siemeister ,  William Scott

发明人： Ulrich Klar ,  Marcus Koppitz ,  Rolf Jautelat ,  Dirk Kosemund ,  Rolf Bohlmann ,  Benjamin Bader ,  Philip Lienau ,  Gerhard Siemeister ,  William Scott

IPC分类号： C07D487/04

CPC分类号： C07D487/04 ,  A61K31/4985

摘要： The present invention relates to substituted imidazopyrazine compounds of general formula (I) in which A, R1, R3 and R5 are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, as well as to intermediate compounds useful in the preparation of said compounds.

摘要翻译： 本发明涉及通式（I）的取代咪唑并吡嗪化合物，其中A，R 1，R 3和R 5如在说明书和权利要求书中所述，涉及制备所述化合物的方法，药物组合物和包含所述化合物的组合， 涉及用于制备用于治疗或预防疾病的药物组合物的所述化合物的使用，以及可用于制备所述化合物的中间体化合物。

公开(公告)号：US20130195848A1

公开(公告)日：2013-08-01

申请号：US13635734

申请日：2011-03-16

申请人： Ulrich Klar ,  Marcus Koppitz ,  Dirk Kosemund ,  Rolf Bohlmann ,  Benjamin Bader ,  Philip Lienau ,  Gerhard Siemeister ,  Stefan Prechtl ,  Duy Nguyen ,  William Scott

发明人： Ulrich Klar ,  Marcus Koppitz ,  Dirk Kosemund ,  Rolf Bohlmann ,  Benjamin Bader ,  Philip Lienau ,  Gerhard Siemeister ,  Stefan Prechtl ,  Duy Nguyen ,  William Scott

IPC分类号： A61K31/519 ,  A61K45/06 ,  C07D487/04

CPC分类号： A61K31/519 ,  A61K45/06 ,  C07D487/04 ,  C07D487/14

摘要： The present invention relates to imidazopyrazine compounds of general Formula (I): in which X, R1, R2, R3a, R3b, R4a, R4b, R4C, and R4D are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, as well as to intermediate compounds useful in the preparation of said compounds.

摘要翻译： 本发明涉及通式（I）的咪唑并吡嗪化合物：其中X，R1，R2，R3a，R3b，R4a，R4b，R4C和R4D如说明书和权利要求书中所给出的，涉及制备所述 化合物，包含所述化合物的药物组合物和组合，用于制备用于治疗或预防疾病的药物组合物的所述化合物的用途，以及可用于制备所述化合物的中间体化合物。

公开(公告)号：USD679094S1

公开(公告)日：2013-04-02

申请号：US29391492

申请日：2011-05-10

申请人： William Scott

设计人： William Scott