公开(公告)号：US08421031B2

公开(公告)日：2013-04-16

申请号：US13258772

申请日：2011-03-10

申请人： Taizo Honda ,  Masahiro Ikeda ,  Yuehu Pu ,  Kazushi Hanakawa

发明人： Taizo Honda ,  Masahiro Ikeda ,  Yuehu Pu ,  Kazushi Hanakawa

IPC分类号： H01J3/26 ,  A61N5/10

CPC分类号： A61N5/1043 ,  A61N5/1048 ,  A61N5/1077 ,  A61N2005/1074 ,  A61N2005/1087

摘要： The objective is to obtain a particle beam therapy system that can suppress the effect of a leakage dose. There are provided a scanning nozzle that irradiates in a predetermined direction a particle beam emitted from an accelerator; an irradiation control unit that controls operation of the irradiation nozzle in such a way that the particle beam of a predetermined dose is sequentially irradiated onto each of a plurality of spots set in a planar direction in an irradiation subject; and a control unit that on/off-controls emission of the particle beam from the accelerator. The irradiation control unit makes the irradiation nozzle scan in a diluting manner the particle beam onto a predetermined area in the irradiation subject, in a predetermined period after a time point when emission is switched from ON to OFF, or in a period from the time point when emission is switched from ON to OFF to a time point when the particle beam is cut off.

摘要翻译： 目的是获得能够抑制泄漏剂量影响的粒子束治疗系统。 提供了沿预定方向照射从加速器发射的粒子束的扫描喷嘴; 照射控制单元，其以照射对象的平面方向上设置的多个点顺序地照射预定剂量的粒子束的方式控制照射喷嘴的动作; 以及控制单元，其控制来自加速器的粒子束的发射。 照射控制单元使得照射喷嘴在发射从ON切换到OFF之后的预定时间内或在从时间点开始的时间段内，将粒子束以稀释的方式扫描到照射对象的预定区域上 当发射从ON切换到截止到粒子束的时间点时。

公开(公告)号：US08389952B2

公开(公告)日：2013-03-05

申请号：US13322201

申请日：2011-04-13

申请人： Takaaki Iwata ,  Yuehu Pu

发明人： Takaaki Iwata ,  Yuehu Pu

IPC分类号： H01J3/26 ,  H01J1/50 ,  A61N5/00

CPC分类号： G21K1/093 ,  A61N5/1043 ,  A61N2005/1087

摘要： There is provided a particle beam irradiation apparatus in which two or more pairs of scanning electromagnets are utilized so that scanning of a charged particle beam can be performed with a high accuracy and with a high flexibility in the speed, from a low speed to a high speed. In a particle beam irradiation apparatus that scans an incident charged particle beam on X-direction and Y-direction (two-direction) desired orbits perpendicular to the travelling direction of the charged particle beam and irradiates the charged particle beam onto an irradiation subject, there are provided two or more pairs of scanning electromagnets that scan a charged particle beam in the two directions; the desired orbit is given by time-series desired orbit data in which desired irradiation positions corresponding to time are determined; and command values for respective scanning electromagnets in the two or more pairs of scanning electromagnets are generated based on plural pieces of data obtained by frequency-separating the time-series desired orbit data.

摘要翻译： 提供了一种使用两对或更多对扫描电磁体的粒子束照射装置，从而能够以高精度和高速度地从低速到高的灵活性进行带电粒子束的扫描 速度。 在沿着与带电粒子束的行进方向垂直的X方向和Y方向（双向）期望的轨道扫描入射带电粒子束的粒子束照射装置中，将带电粒子束照射到照射对象上， 设置两对或更多对在两个方向扫描带电粒子束的扫描电磁体对; 期望的轨道由时间序列期望的轨道数据给出，其中确定对应于时间的期望的照射位置; 并且基于通过对时间序列期望的轨道数据进行频率分离而获得的多条数据，生成两对以上的扫描电磁体对的各扫描电磁体的指令值。

公开(公告)号：US20120132826A1

公开(公告)日：2012-05-31

申请号：US13322201

申请日：2011-04-13

申请人： Takaaki Iwata ,  Yuehu Pu

发明人： Takaaki Iwata ,  Yuehu Pu

IPC分类号： H01J3/26

CPC分类号： G21K1/093 ,  A61N5/1043 ,  A61N2005/1087

摘要： There is provided a particle beam irradiation apparatus in which two or more pairs of scanning electromagnets are utilized so that scanning of a charged particle beam can be performed with a high accuracy and with a high flexibility in the speed, from a low speed to a high speed. In a particle beam irradiation apparatus that scans an incident charged particle beam on X-direction and Y-direction (two-direction) desired orbits perpendicular to the travelling direction of the charged particle beam and irradiates the charged particle beam onto an irradiation subject, there are provided two or more pairs of scanning electromagnets that scan a charged particle beam in the two directions; the desired orbit is given by time-series desired orbit data in which desired irradiation positions corresponding to time are determined; and command values for respective scanning electromagnets in the two or more pairs of scanning electromagnets are generated based on plural pieces of data obtained by frequency-separating the time-series desired orbit data.

摘要翻译： 提供了一种使用两对或更多对扫描电磁体的粒子束照射装置，从而能够以高精度和高速度地从低速到高的灵活性进行带电粒子束的扫描 速度。 在沿着与带电粒子束的行进方向垂直的X方向和Y方向（双向）期望的轨道扫描入射带电粒子束的粒子束照射装置中，将带电粒子束照射到照射对象上， 设置两对或更多对在两个方向扫描带电粒子束的扫描电磁体对; 期望的轨道由时间序列期望的轨道数据给出，其中确定对应于时间的期望的照射位置; 并且基于通过对时间序列期望的轨道数据进行频率分离而获得的多条数据，生成两对以上的扫描电磁体对的各扫描电磁体的指令值。

公开(公告)号：US20120228521A1

公开(公告)日：2012-09-13

申请号：US13258772

申请日：2011-03-10

申请人： Taizo Honda ,  Masahiro Ikeda ,  Yuehu Pu ,  Kazushi Hanakawa

发明人： Taizo Honda ,  Masahiro Ikeda ,  Yuehu Pu ,  Kazushi Hanakawa

IPC分类号： A61N5/00

CPC分类号： A61N5/1043 ,  A61N5/1048 ,  A61N5/1077 ,  A61N2005/1074 ,  A61N2005/1087

摘要： The objective is to obtain a particle beam therapy system that can suppress the effect of a leakage dose. There are provided a scanning nozzle that irradiates in a predetermined direction a particle beam emitted from an accelerator; an irradiation control unit that controls operation of the irradiation nozzle in such a way that the particle beam of a predetermined dose is sequentially irradiated onto each of a plurality of spots set in a planar direction in an irradiation subject; and a control unit that on/off-controls emission of the particle beam from the accelerator. The irradiation control unit makes the irradiation nozzle scan in a diluting manner the particle beam onto a predetermined area in the irradiation subject, in a predetermined period after a time point when emission is switched from ON to OFF, or in a period from the time point when emission is switched from ON to OFF to a time point when the particle beam is cut off.

摘要翻译： 目的是获得能够抑制泄漏剂量影响的粒子束治疗系统。 提供了沿预定方向照射从加速器发射的粒子束的扫描喷嘴; 照射控制单元，其以照射对象的平面方向上设置的多个点顺序地照射预定剂量的粒子束的方式控制照射喷嘴的动作; 以及控制单元，其控制来自加速器的粒子束的发射。 照射控制单元使得照射喷嘴在发射从ON切换到OFF之后的预定时间内或在从时间点开始的时间段内，将粒子束以稀释的方式扫描到照射对象的预定区域上 当发射从ON切换到截止到粒子束的时间点时。

公开(公告)号：US09079026B2

公开(公告)日：2015-07-14

申请号：US14386626

申请日：2012-03-21

申请人： Yuehu Pu ,  Masahiro Ikeda ,  Taizo Honda

发明人： Yuehu Pu ,  Masahiro Ikeda ,  Taizo Honda

IPC分类号： A61N5/10

CPC分类号： A61N5/1071 ,  A61N5/103 ,  A61N5/1031 ,  A61N5/1043 ,  A61N2005/1087

摘要： A particle beam scanning irradiation method includes the steps of calculating a planned irradiating particle count of a particle beam for each of irradiation spots, on the basis of a relative amount of particle beam irradiation and a prescription particle-beam dose determined from a particle-beam therapy plan; simulating an irradiation process of the particle beam at each irradiation spot, on the basis of the planned irradiating particle count and a beam current waveform of the particle beam, and calculating a particle count of the particle beam irradiating the diseased portion during a scan shift of the particle beam; correcting the planned irradiating particle count for each irradiation spot by using the irradiating particle count during the scan shift; converting the corrected planned-irradiation particle count into a count value used in a dose monitor; and irradiating the irradiation spot with the particle beam, on the basis of the converted count value.

摘要翻译： 粒子束扫描照射方法包括以下步骤：基于粒子束照射的相对量和从粒子束确定的处方粒子束剂量来计算每个照射点的粒子束的计划照射粒子数 治疗方案; 基于所计划的照射粒子数和粒子束的束电流波形，模拟在各照射点处的粒子束的照射过程，计算在扫描位移期间照射患病部位的粒子束的粒子数 粒子束; 通过使用扫描偏移期间的照射粒子数来校正每个照射点的计划照射粒子数; 将校正的计划照射粒子数转换为剂量监视器中使用的计数值; 并且基于转换后的计数值，用粒子束照射照射点。

公开(公告)号：US07579608B2

公开(公告)日：2009-08-25

申请号：US11870512

申请日：2007-10-11

申请人： Osamu Takahashi ,  Yuehu Pu ,  Hisashi Harada ,  Masahiro Ikeda ,  Yasuyuki Takatani ,  Hiroshi Otani

发明人： Osamu Takahashi ,  Yuehu Pu ,  Hisashi Harada ,  Masahiro Ikeda ,  Yasuyuki Takatani ,  Hiroshi Otani

IPC分类号： G21K5/04

CPC分类号： A61N5/1042 ,  A61B5/1127 ,  A61N5/1064 ,  A61N2005/1059 ,  A61N2005/1087 ,  G21K1/046

摘要： Provision is made for a particle-beam treatment system in which, even during particle-beam irradiation, the shape of a multileaf collimator is monitored. The particle-beam treatment system, in which multi-layer conformal irradiation is performed while the setting of the shape of the multileaf collimator in an irradiation head is changed during particle-beam irradiation, is provided with an optical shape-monitoring unit mounted attachably and detachably in the snout portion at the downstream side of the multileaf collimator, the optical shape-monitoring unit having a shape-monitoring mirror, opposing the multileaf collimator, for monitoring the shape of the multileaf collimator; a video camera for shooting the multileaf-collimator shape reflected by the shape-monitoring mirror; and an image monitor for displaying an image of the video camera that shoots the shape of the multileaf collimator.

摘要翻译： 规定了一种粒子束处理系统，其中即使在粒子束照射期间，监视多叶准直器的形状。 在粒子束照射期间，在照射头中的多叶准直器的形状的设定被改变的同时进行多层共形照射的粒子束处理系统设置有可安装地安装的光学形状监视单元， 所述光学形状监视单元具有与所述多叶准直器相对的形状监视镜，用于监视所述多叶准直器的形状; 用于拍摄由形状监视镜反射的多叶准直器形状的摄像机; 以及用于显示拍摄多叶准直器的形状的摄像机的图像的图像监视器。

公开(公告)号：US20080298553A1

公开(公告)日：2008-12-04

申请号：US11870512

申请日：2007-10-11

申请人： Osamu Takahashi ,  Yuehu Pu ,  Hisashi Harada ,  Masahiro Ikeda ,  Yasuyuki Takatani ,  Hiroshi Otani

发明人： Osamu Takahashi ,  Yuehu Pu ,  Hisashi Harada ,  Masahiro Ikeda ,  Yasuyuki Takatani ,  Hiroshi Otani

IPC分类号： G21K5/04

CPC分类号： A61N5/1042 ,  A61B5/1127 ,  A61N5/1064 ,  A61N2005/1059 ,  A61N2005/1087 ,  G21K1/046

摘要： Provision is made for a particle-beam treatment system in which, even during particle-beam irradiation, the shape of a multileaf collimator is monitored. The particle-beam treatment system, in which multi-layer conformal irradiation is performed while the setting of the shape of the multileaf collimator in an irradiation head is changed during particle-beam irradiation, is provided with an optical shape-monitoring unit mounted attachably and detachably in the snout portion at the downstream side of the multileaf collimator, the optical shape-monitoring unit having a shape-monitoring mirror, opposing the multileaf collimator, for monitoring the shape of the multileaf collimator; a video camera for shooting the multileaf-collimator shape reflected by the shape-monitoring mirror; and an image monitor for displaying an image of the video camera that shoots the shape of the multileaf collimator.

摘要翻译： 规定了一种粒子束处理系统，其中即使在粒子束照射期间，监视多叶准直器的形状。 在粒子束照射期间，在照射头中的多叶准直器的形状的设定被改变的同时进行多层共形照射的粒子束处理系统设置有可安装地安装的光学形状监视单元， 所述光学形状监视单元具有与所述多叶准直器相对的形状监视镜，用于监视所述多叶准直器的形状; 用于拍摄由形状监视镜反射的多叶准直器形状的摄像机; 以及用于显示拍摄多叶准直器的形状的摄像机的图像的图像监视器。

公开(公告)号：US08222613B2

公开(公告)日：2012-07-17

申请号：US12574136

申请日：2009-10-06

申请人： Shinya Tajiri ,  Yuichi Yamamoto ,  Yuehu Pu ,  Haruo Yamashita

发明人： Shinya Tajiri ,  Yuichi Yamamoto ,  Yuehu Pu ,  Haruo Yamashita

IPC分类号： G01K1/08 ,  H01J3/14 ,  H01J3/26

CPC分类号： G21K1/093 ,  A61N5/1042 ,  A61N5/1043 ,  A61N5/1078 ,  A61N5/1084 ,  A61N2005/1087 ,  G21K5/00

摘要： An inexpensive scanning irradiation device of a particle beam is obtained without using a rotating gantry. A first scanning electromagnet and a second scanning electromagnet, whose deflection surfaces of the particle beam are the same, and which bend the particle beam having an incident beam axis angle of approximately 45 degrees relative to a horizontal direction in reverse directions to each other; an electromagnet rotation driving mechanism which integrates the first and the second scanning electromagnets and rotates these scanning electromagnets around the incident beam axis; and a treatment bed are provided. The particle beam deflected by the first and the second scanning electromagnets can be obtained at a range of −45 degrees to +45 degrees in deflection angle from an incident beam axis direction.

摘要翻译： 在不使用旋转机架的情况下获得粒子束的便宜的扫描照射装置。 第一扫描电磁体和第二扫描电磁体，其粒子束的偏转面相同，并且使相对于水平方向的相反方向的入射光束轴角大约为45度的粒子束彼此弯曲; 电磁体旋转驱动机构，其对第一和第二扫描电磁体进行积分并使这些扫描电磁体绕入射光束轴线旋转; 并提供治疗床。 由第一和第二扫描电磁体偏转的粒子束可以在从入射光束轴方向偏转角度-45度至+45度的范围内获得。

公开(公告)号：US20100090123A1

公开(公告)日：2010-04-15

申请号：US12574136

申请日：2009-10-06

申请人： Shinya Tajiri ,  Yuichi Yamamoto ,  Yuehu Pu ,  Haruo Yamashita

发明人： Shinya Tajiri ,  Yuichi Yamamoto ,  Yuehu Pu ,  Haruo Yamashita

IPC分类号： H01J3/26 ,  H01J1/50

CPC分类号： G21K1/093 ,  A61N5/1042 ,  A61N5/1043 ,  A61N5/1078 ,  A61N5/1084 ,  A61N2005/1087 ,  G21K5/00

摘要： An inexpensive scanning irradiation device of a particle beam is obtained without using a rotating gantry. A first scanning electromagnet and a second scanning electromagnet, whose deflection surfaces of the particle beam are the same, and which bend the particle beam having an incident beam axis angle of approximately 45 degrees relative to a horizontal direction in reverse directions to each other; an electromagnet rotation driving mechanism which integrates the first and the second scanning electromagnets and rotates these scanning electromagnets around the incident beam axis; and a treatment bed are provided. The particle beam deflected by the first and the second scanning electromagnets can be obtained at a range of −45 degrees to +45 degrees in deflection angle from an incident beam axis direction.

摘要翻译： 在不使用旋转机架的情况下获得粒子束的便宜的扫描照射装置。 第一扫描电磁体和第二扫描电磁体，其粒子束的偏转面相同，并且使相对于水平方向的相反方向的入射光束轴角大约为45度的粒子束彼此弯曲; 电磁体旋转驱动机构，其对第一和第二扫描电磁体进行积分并使这些扫描电磁体绕入射光束轴线旋转; 并提供治疗床。 由第一和第二扫描电磁体偏转的粒子束可以在从入射光束轴方向偏转角度-45度至+45度的范围内获得。

公开(公告)号：US06034377A

公开(公告)日：2000-03-07

申请号：US69944

申请日：1998-04-30

申请人： Yuehu Pu

发明人： Yuehu Pu

IPC分类号： G21K1/093 ,  A61N5/10 ,  G21K5/02 ,  G21K5/04 ,  G21K5/10 ,  A61N5/00

CPC分类号： A61N5/1043 ,  G21K5/02 ,  G21K5/10 ,  A61N2005/1087 ,  A61N2005/1095

摘要： A charged particle beam irradiation apparatus includes two electromagnets arranged in series along a direction of an incident axis of a charged particle beam, for deflecting the charged particle beam in opposite directions, an energy modulator including a cylindrical member having a length and a distribution of wall thickness in a circumferential direction, a first rotational drive for rotating the cylindrical member around a rotation axis, and a detector for detecting the angular position of the cylindrical member. The energy modulator is disposed at a downstream side of the scanning electromagnets so that the deflected charged particle beam passes through the rotation axis. The apparatus includes an energy degrader for limiting energy of the charged particle beam, and a second rotational drive for rotating the scanning electromagnets and the energy modulator together around the incident axis of the charged particle beam.

摘要翻译： 带电粒子束照射装置包括沿着带电粒子束的入射轴的方向串联布置的两个电磁体，用于使带电粒子束沿相反方向偏转，能量调制器包括具有长度和壁分布的圆柱形构件 在圆周方向上的厚度，用于使圆筒形构件围绕旋转轴线旋转的第一旋转驱动器和用于检测圆柱形构件的角位置的检测器。 能量调制器设置在扫描电磁体的下游侧，使得偏转的带电粒子束通过旋转轴。 该装置包括用于限制带电粒子束的能量的能量降解器，以及用于围绕带电粒子束的入射轴旋转扫描电磁体和能量调制器的第二旋转驱动器。