公开(公告)号：US20110009619A1

公开(公告)日：2011-01-13

申请号：US12671873

申请日：2008-08-28

申请人： Teiji Kimura ,  Noritaka Kitazawa ,  Toshihiko Kaneko ,  Nobuaki Sato ,  Koki Kawano ,  Koichi Ito ,  Mamoru Takaishi ,  Takeo Sasaki ,  Yu Yoshida ,  Toshiyuki Uemura ,  Takashi Doko ,  Daisuke Shinmyo ,  Daiju Hasegawa ,  Takehiko Miyagawa ,  Hiroaki Hagiwara

发明人： Teiji Kimura ,  Noritaka Kitazawa ,  Toshihiko Kaneko ,  Nobuaki Sato ,  Koki Kawano ,  Koichi Ito ,  Mamoru Takaishi ,  Takeo Sasaki ,  Yu Yoshida ,  Toshiyuki Uemura ,  Takashi Doko ,  Daisuke Shinmyo ,  Daiju Hasegawa ,  Takehiko Miyagawa ,  Hiroaki Hagiwara

IPC分类号： C07D487/04 ,  C07D471/04 ,  C07D498/04

CPC分类号： C07D403/10 ,  C07D471/04 ,  C07D487/04 ,  C07D498/04

摘要： Disclosed is a compound represented by the formula (I): or a pharmacologically acceptable salt thereof, which is effective as a therapeutic or prophylactic agent for a disease induced by Aβ, wherein Ar1 represents an imidazolyl group which may be substituted with a C1-6 alkyl group, or the like; Ar2 represents a phenyl group which may be substituted with a C1-6 alkoxy group, or the like; X1 represents a double bond, or the like; and Het represents a triazolyl group or the like which may be substituted with a C1-6 alkyl group or the like, or the like.

摘要翻译： 公开了由式（I）表示的化合物或其药理学上可接受的盐，其作为由A＆bgr诱导的疾病的治疗或预防剂是有效的，其中Ar1表示可被C1- 6烷基等; Ar 2表示可被C 1-6烷氧基取代的苯基等; X1表示双键等; Het表示可以被C 1-6烷基等取代的三唑基等。

公开(公告)号：US07935815B2

公开(公告)日：2011-05-03

申请号：US12200731

申请日：2008-08-28

申请人： Teiji Kimura ,  Noritaka Kitazawa ,  Toshihiko Kaneko ,  Nobuaki Sato ,  Koki Kawano ,  Koichi Ito ,  Mamoru Takaishi ,  Takeo Sasaki ,  Yu Yoshida ,  Toshiyuki Uemura ,  Takashi Doko ,  Daisuke Shinmyo ,  Daiju Hasegawa ,  Takehiko Miyagawa ,  Hiroaki Hagiwara

发明人： Teiji Kimura ,  Noritaka Kitazawa ,  Toshihiko Kaneko ,  Nobuaki Sato ,  Koki Kawano ,  Koichi Ito ,  Mamoru Takaishi ,  Takeo Sasaki ,  Yu Yoshida ,  Toshiyuki Uemura ,  Takashi Doko ,  Daisuke Shinmyo ,  Daiju Hasegawa ,  Takehiko Miyagawa ,  Hiroaki Hagiwara

IPC分类号： C07D491/00 ,  C07D513/00 ,  C07D515/00 ,  C07D265/36 ,  C07D498/02 ,  C07D487/00 ,  C07D513/02 ,  C07D515/02 ,  C07D401/00

CPC分类号： C07D403/10 ,  C07D401/14 ,  C07D403/14 ,  C07D409/14

摘要： A compound represented by the formula (I): or a pharmacologically acceptable salt thereof, wherein Ar1 represents an imidazolyl group or the like which may be substituted with a C1-6 alkyl group, Ar2 represents a phenyl group or the like which may be substituted with a C1-6 alkoxy group, X1 represents a double bond or the like and Het represents a triazolyl group or the like which may be substituted with a C1-6 alkyl group or the like, is effective as a therapeutic or prophylactic agent for a disease caused by Aβ.

摘要翻译： 由式（I）表示的化合物或其药理学上可接受的盐，其中Ar 1表示可被C 1-6烷基取代的咪唑基等，Ar 2表示可被取代的苯基等 具有C 1-6烷氧基，X 1表示双键等，Het表示可以被C 1-6烷基等取代的三唑基等，作为治疗或预防药物是有效的 A＆BGR引起的疾病

公开(公告)号：US20090062529A1

公开(公告)日：2009-03-05

申请号：US12200731

申请日：2008-08-28

申请人： Teiji KIMURA ,  Noritaka Kitazawa ,  Toshihiko Kaneko ,  Nobuaki Sato ,  Koki Kawano ,  Koichi Ito ,  Mamoru Takaishi ,  Takeo Sasaki ,  Yu Yoshida ,  Toshiyuki Uemura ,  Takashi Doko ,  Daisuke Shinmyo ,  Daiju Hasegawa ,  Takehiko Miyagawa ,  Hiroaki Hagiwara

发明人： Teiji KIMURA ,  Noritaka Kitazawa ,  Toshihiko Kaneko ,  Nobuaki Sato ,  Koki Kawano ,  Koichi Ito ,  Mamoru Takaishi ,  Takeo Sasaki ,  Yu Yoshida ,  Toshiyuki Uemura ,  Takashi Doko ,  Daisuke Shinmyo ,  Daiju Hasegawa ,  Takehiko Miyagawa ,  Hiroaki Hagiwara

IPC分类号： C07D487/04 ,  C07D498/04

CPC分类号： C07D403/10 ,  C07D401/14 ,  C07D403/14 ,  C07D409/14

摘要： A compound represented by the formula (I): or a pharmacologically acceptable salt thereof, wherein Ar1 represents an imidazolyl group or the like which may be substituted with a C1-6 alkyl group, Ar2 represents a phenyl group or the like which may be substituted with a C1-6 alkoxy group, X1 represents a double bond or the like and Het represents a triazolyl group or the like which may be substituted with a C1-6 alkyl group or the like, is effective as a therapeutic or prophylactic agent for a disease caused by Aβ.

摘要翻译： 由式（I）表示的化合物或其药理学上可接受的盐，其中Ar 1表示可被C 1-6烷基取代的咪唑基等，Ar 2表示可被取代的苯基等 具有C 1-6烷氧基，X 1表示双键等，Het表示可以被C 1-6烷基等取代的三唑基等，作为治疗或预防药物是有效的 由Abeta引起的疾病

公开(公告)号：US09453000B2

公开(公告)日：2016-09-27

申请号：US12671873

申请日：2008-08-28

申请人： Teiji Kimura ,  Noritaka Kitazawa ,  Toshihiko Kaneko ,  Nobuaki Sato ,  Koki Kawano ,  Koichi Ito ,  Mamoru Takaishi ,  Takeo Sasaki ,  Yu Yoshida ,  Toshiyuki Uemura ,  Takashi Doko ,  Daisuke Shinmyo ,  Daiju Hasegawa ,  Takehiko Miyagawa ,  Hiroaki Hagiwara

发明人： Teiji Kimura ,  Noritaka Kitazawa ,  Toshihiko Kaneko ,  Nobuaki Sato ,  Koki Kawano ,  Koichi Ito ,  Mamoru Takaishi ,  Takeo Sasaki ,  Yu Yoshida ,  Toshiyuki Uemura ,  Takashi Doko ,  Daisuke Shinmyo ,  Daiju Hasegawa ,  Takehiko Miyagawa ,  Hiroaki Hagiwara

IPC分类号： C07D471/04 ,  A61K31/437 ,  C07D487/04 ,  C07D498/04 ,  C07D403/10 ,  A61P25/28 ,  C07D403/04

CPC分类号： C07D403/10 ,  C07D471/04 ,  C07D487/04 ,  C07D498/04

摘要： Disclosed is a compound represented by the formula (I): or a pharmacologically acceptable salt thereof, which is effective as a therapeutic or prophylactic agent for a disease induced by Aβ, wherein Ar1 represents an imidazolyl group which may be substituted with a C1-6 alkyl group, or the like; Ar2 represents a phenyl group which may be substituted with a C1-6 alkoxy group, or the like; X1 represents a double bond, or the like; and Het represents a triazolyl group or the like which may be substituted with a C1-6 alkyl group or the like, or the like.

公开(公告)号：US07667041B2

公开(公告)日：2010-02-23

申请号：US11136355

申请日：2005-05-25

申请人： Teiji Kimura ,  Koki Kawano ,  Eriko Doi ,  Noritaka Kitazawa ,  Kogyoku Shin ,  Takehiko Miyagawa ,  Toshihiko Kaneko ,  Koichi Ito ,  Mamoru Takaishi ,  Hiroaki Hagiwara

发明人： Teiji Kimura ,  Koki Kawano ,  Eriko Doi ,  Noritaka Kitazawa ,  Kogyoku Shin ,  Takehiko Miyagawa ,  Toshihiko Kaneko ,  Koichi Ito ,  Mamoru Takaishi ,  Hiroaki Hagiwara

IPC分类号： C07D401/00 ,  A61K31/54

CPC分类号： C07D401/10 ,  C07D401/12 ,  C07D405/12 ,  C07D409/12 ,  C07D409/14 ,  C07D413/10 ,  C07D413/12 ,  C07D413/14 ,  C07D417/10 ,  C07D417/12 ,  C07D417/14 ,  C07D487/04

摘要： The present invention relates to a compound represented by Formula (I): (wherein Ar1 represents an imidazolyl group which may be substituted with 1 to 3 substituents; Ar2 represents a pyridinyl group, a pyrimidinyl group, or a phenyl group which may be substituted with 1 to 3 substituents; X1 represents (1) —C≡C— or (2) a double bond etc. which may be substituted; R1 and R2 represent, for example, a C1-6 alkyl group or C3-8 cycloalkyl group which may be substituted) or a pharmacologically acceptable salt thereof and to the use thereof as pharmaceutical agents. The object of the present invention is to find a therapeutic or preventive agent for diseases caused by Aβ. According to the present invention, a therapeutic or preventive agents for diseases caused by Aβ can be provided.

摘要翻译： 本发明涉及由式（I）表示的化合物：其中Ar 1表示可被1〜3个取代基取代的咪唑基; Ar 2表示吡啶基，嘧啶基或可被 1〜3个取代基; X1表示（1）-C≡C-或（2）可被取代的双键等; R 1和R 2表示例如C 1-6烷基或C 3-8环烷基， 可以被取代）或其药理学上可接受的盐及其作为药剂的用途。 本发明的目的是找到由A＆Bgr引起的疾病的治疗或预防剂。 根据本发明，由A＆Bgr引起的疾病的治疗或预防剂; 可以提供。

公开(公告)号：US07985702B2

公开(公告)日：2011-07-26

申请号：US12746384

申请日：2008-10-16

申请人： Kenichiro Kano ,  Takashi Tsuruta ,  Mamoru Kitamura ,  Hideo Isoda ,  Hiroaki Hagiwara ,  Gaku Maruyama ,  Takahiro Hattori

发明人： Kenichiro Kano ,  Takashi Tsuruta ,  Mamoru Kitamura ,  Hideo Isoda ,  Hiroaki Hagiwara ,  Gaku Maruyama ,  Takahiro Hattori

IPC分类号： B32B27/34

CPC分类号： B60R21/235 ,  B60R2021/23514 ,  D03D1/02 ,  D03D15/0088 ,  D06M15/263 ,  D06M15/507 ,  D06M15/568 ,  D06M15/59 ,  D06N3/0002 ,  D06N3/042 ,  D06N3/121 ,  D06N3/125 ,  D06N3/14 ,  Y10T428/24612 ,  Y10T442/2139 ,  Y10T442/2811

摘要： A woven fabric for an airbag includes a synthetic fiber woven fabric having a cover factor of 2000 to 2500 in which at least one side thereof is coated with a synthetic resin. Air permeability of the woven fabric under a pressure difference of 100 kPa is 0.01 to 1.00 L/cm2/min. A resin film is present at an upper part of a single yarn at a thickness of 2 μm or less on a central cross section of a weaving yarn part. A resin film is present at an upper part of a single yarn at a thickness of 2 to 30 μm on a cross section at a border between weaving yarn parts. The synthetic resin can be a polyamide-based resin that includes a polyether compound of a number average molecular weight of 100 to 5000 as a soft segment.

摘要翻译： 一种用于气囊的机织织物包括具有2000至2500的覆盖系数的合成纤维织物，其中至少一侧涂覆有合成树脂。 在100kPa的压力差下，织物的透气度为0.01〜1.00L / cm 2 /分钟。 在织造纱线部分的中心横截面处，在单根纱线的上部以2μm以下的厚度存在树脂膜。 在织造纱线部分之间的边界处的横截面上，在单纱的上部存在2〜30μm的树脂膜。 合成树脂可以是包含作为软链段的数均分子量为100〜5000的聚醚化合物的聚酰胺类树脂。

公开(公告)号：US20100282358A1

公开(公告)日：2010-11-11

申请号：US12746389

申请日：2008-10-16

申请人： Kenichiro Kano ,  Takashi Tsuruta ,  Hideo Isoda ,  Hiroaki Hagiwara ,  Gaku Maruyama ,  Takahiro Hattori

发明人： Kenichiro Kano ,  Takashi Tsuruta ,  Hideo Isoda ,  Hiroaki Hagiwara ,  Gaku Maruyama ,  Takahiro Hattori

IPC分类号： D03D1/02 ,  B60R21/16 ,  D06M15/693

CPC分类号： B60R21/235 ,  B60R2021/23514 ,  D03D1/02 ,  D06M15/59 ,  D06N3/0002 ,  D06N3/125 ,  Y10T442/2139 ,  Y10T442/2811

摘要： An object of the present invention is to provide a fabric for an airbag which is of low cost, is excellent in accommodability, and has air permeability satisfying the human body initial constraining performance.The present invention provides a fabric for an airbag comprising a synthetic fiber woven fabric in which at least one side thereof is coated with a synthetic resin, characterized in that a range of 0.1 to 10 g/m2 of a synthetic resin is adhered to the synthetic fiber woven fabric having a cover factor represented by the equation 1 of less than 2000 and FR represented by the equation 2 of 55% or more, and air permeability of the fabric under a pressure difference of 100 kPa after adhesion is 0.01 to 1.00 L/cm2/min.

摘要翻译： 本发明的目的在于提供一种低成本，优良的适应性，并具有满足人体初始约束性能的透气性的气囊用织物。 本发明提供了一种用于气囊的织物，其包括合成纤维织物，其中至少一侧涂覆有合成树脂，其特征在于，将合成树脂的0.1至10g / m 2的范围粘附到合成树脂 具有小于2000的等式1表示的覆盖系数的纤维编织物，等式2表示的FR为55％以上，粘合后的压力差为100kPa的织物的透气性为0.01〜1.00L / cm2 / min。

公开(公告)号：US20110097955A1

公开(公告)日：2011-04-28

申请号：US12981372

申请日：2010-12-29

申请人： Kenichiro Kano ,  Takashi Tsuruta ,  Mamoru Kitamura ,  Hideo Isoda ,  Hiroaki Hagiwara ,  Gaku Maruyama ,  Takahiro Hattori

发明人： Kenichiro Kano ,  Takashi Tsuruta ,  Mamoru Kitamura ,  Hideo Isoda ,  Hiroaki Hagiwara ,  Gaku Maruyama ,  Takahiro Hattori

IPC分类号： B32B5/24

CPC分类号： B60R21/235 ,  B60R2021/23514 ,  D03D1/02 ,  D03D15/0088 ,  D06M15/263 ,  D06M15/507 ,  D06M15/568 ,  D06M15/59 ,  D06N3/0002 ,  D06N3/042 ,  D06N3/121 ,  D06N3/125 ,  D06N3/14 ,  Y10T428/24612 ,  Y10T442/2139 ,  Y10T442/2811

摘要： An object of the present invention is to provide a woven fabric for an airbag which is of low cost, is excellent in accommodability, and has air permeability satisfying the human body initial constraining performance.The present invention provides a woven fabric for an airbag comprising a synthetic fiber woven fabric having a cover factor represented by the equation 1 of 2000 to 2500 in which at least one side thereof is coated with a synthetic resin, wherein air permeability of the woven fabric under a pressure difference of 100 kPa is 0.01 to 1.00 L/cm2/min, and a resin film is present at an upper part of a single yarn at a thickness of 2 μm or less on a central cross section of a weaving yarn part, while a resin film is present at an upper part of a single yarn at a thickness of 2 to 30 μm on a cross section at a border between weaving yarn parts.

摘要翻译： 本发明的目的是提供一种低成本，优良的适应性的气囊用织物，并且具有满足人体初始约束性能的透气性。 本发明提供一种用于气囊的机织织物，其包括合成纤维织物，其具有由2000至2500的等式1表示的覆盖系数，其中至少一侧涂覆有合成树脂，其中织物的透气性 在100kPa的压力差为0.01〜1.00L / cm 2 / min的范围内，在织造纱部的中央截面为2μm以下的单纱的上部存在树脂膜， 而在编织纱线部分之间的边界处的横截面上，单根纱线的上部存在树脂膜，厚度为2〜30μm。

公开(公告)号：US20110014833A1

公开(公告)日：2011-01-20

申请号：US12935146

申请日：2008-10-16

申请人： Hiroaki Hagiwara ,  Kenichiro Kano ,  Gaku Maruyama ,  Takahiro Hattori ,  Takashi Tsuruta

发明人： Hiroaki Hagiwara ,  Kenichiro Kano ,  Gaku Maruyama ,  Takahiro Hattori ,  Takashi Tsuruta

IPC分类号： B32B5/02 ,  C08G69/14 ,  C08G69/36

CPC分类号： D06M15/59 ,  B60R2021/23514 ,  C08G69/40 ,  C08J5/04 ,  C08J2377/06 ,  C09D177/06 ,  D06N3/125 ,  Y10T442/20 ,  Y10T442/2139 ,  Y10T442/2811

摘要： An object of the present invention is to provide a copolymerized polyether polyamide resin for coating on or for impregnation to a woven or knitted fabric, which resin further enhances slippage resistance and tear strength affecting the developing property of an airbag which is one of the automobile safety parts, as compared with those in the prior art.According to the present invention, a copolymerized polyether polyamide resin for coating on or for impregnation to a woven or knitted fabric is provided, characterized in that, elongation and elastic modulus of the copolymerized polyether polyamide resin are not less than 1000% and not more than 15 MPa, respectively. The copolymerized polyether polyamide resin has a constitution wherein said copolymerized polyether polyamide resin is such that wherein a soft segment comprising a polyether polyamide constituted from a polyether diamine compound and a dicarboxylic acid compound is bonded to a hard segment comprising a polyamide constituted from an aminocarboxylic acid compound and/or a lactam compound.

摘要翻译： 本发明的目的是提供一种用于在机织或针织物上涂布或浸渍的共聚聚醚聚酰胺树脂，该树脂进一步增强了影响作为汽车安全性之一的气囊的显影性能的抗滑性和撕裂强度 部件，与现有技术相比。 根据本发明，提供了用于在机织或针织物上涂布或浸渍于机织或针织织物中的共聚聚醚聚酰胺树脂，其特征在于共聚聚醚聚酰胺树脂的伸长率和弹性模量不小于1000％且不大于 15 MPa。 共聚聚醚聚酰胺树脂具有这样的结构，其中所述共聚聚醚聚酰胺树脂是这样的，其中包含由聚醚二胺化合物和二羧酸化合物构成的聚醚聚酰胺的软链段结合到包含由氨基羧酸 化合物和/或内酰胺化合物。

公开(公告)号：US20100260976A1

公开(公告)日：2010-10-14

申请号：US12746384

申请日：2008-10-16

申请人： Kenichiro Kano ,  Takashi Tsunuta ,  Mamoru Kitamura ,  Hideo Isoda ,  Hiroaki Hagiwara ,  Gaku Maruyama ,  Takahiro Hattori

发明人： Kenichiro Kano ,  Takashi Tsunuta ,  Mamoru Kitamura ,  Hideo Isoda ,  Hiroaki Hagiwara ,  Gaku Maruyama ,  Takahiro Hattori

IPC分类号： D06M15/693 ,  D03D1/02 ,  B32B27/02

CPC分类号： B60R21/235 ,  B60R2021/23514 ,  D03D1/02 ,  D03D15/0088 ,  D06M15/263 ,  D06M15/507 ,  D06M15/568 ,  D06M15/59 ,  D06N3/0002 ,  D06N3/042 ,  D06N3/121 ,  D06N3/125 ,  D06N3/14 ,  Y10T428/24612 ,  Y10T442/2139 ,  Y10T442/2811

摘要： An object of the present invention is to provide a woven fabric for an airbag which is of low cost, is excellent in accommodability, and has air permeability satisfying the human body initial constraining performance.The present invention provides a woven fabric for an airbag comprising a synthetic fiber woven fabric having a cover factor represented by the equation 1 of 2000 to 2500 in which at least one side thereof is coated with a synthetic resin, wherein air permeability of the woven fabric under a pressure difference of 100 kPa is 0.01 to 1.00 L/cm2/min, and a resin film is present at an upper part of a single yarn at a thickness of 2 μm or less on a central cross section of a weaving yarn part, while a resin film is present at an upper part of a single yarn at a thickness of 2 to 30 μm on a cross section at a border between weaving yarn parts.

摘要翻译： 本发明的目的是提供一种低成本，优良的适应性的气囊用织物，并且具有满足人体初始约束性能的透气性。 本发明提供一种用于气囊的机织织物，其包括合成纤维织物，其具有由2000至2500的等式1表示的覆盖系数，其中至少一侧涂覆有合成树脂，其中织物的透气性 在100kPa的压力差为0.01〜1.00L / cm 2 / min的范围内，在织造纱部的中央截面为2μm以下的单纱的上部存在树脂膜， 而在编织纱线部分之间的边界处的横截面上，单根纱线的上部存在树脂膜，厚度为2〜30μm。