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39 条记录 (耗时 0.03 秒)

    Coated stents with better gripping ability
    21.
    发明授权
    Coated stents with better gripping ability 失效
    涂层支架具有更好的抓握能力

    公开(公告)号：US06635078B1

    公开(公告)日：2003-10-21

    申请号：US09667916

    申请日：2000-09-22

    申请人： Sheng-Ping Zhong ,  Steven A. Schultz ,  Kristian J. Dimatteo

    发明人： Sheng-Ping Zhong ,  Steven A. Schultz ,  Kristian J. Dimatteo

    IPC分类号： A61F206

    CPC分类号： A61F2/958 ,  A61F2002/9583

    摘要： A medical device delivery apparatus is provided which comprises a catheter having an expandable and contractible member and an expandable medical device disposed about the expandable and contractible member. At least portions of at least one of the medical device and the expandable and contractible member have a pressure sensitive adhesive applied thereto to adhere the medical device to the expandable and contractible member. The pressure sensitive adhesive is selected so as to release the medical device from the expandable and contractible member upon contraction of the member from an expanded state. Suitable medical devices include stents.

    摘要翻译： 提供了一种医疗装置输送装置，其包括具有可膨胀和收缩构件的导管和围绕可膨胀和收缩构件设置的可扩张医疗装置。 医疗装置和可扩张和收缩部件中的至少一个的至少一部分具有施加到其上的压敏粘合剂，以将医疗装置粘附到可膨胀和收缩的部件上。 选择压敏粘合剂，以在构件从膨胀状态收缩时将医疗装置从可膨胀和收缩构件释放。 合适的医疗设备包括支架。

    Device with enhanced indication of use and prevention of re-use
    24.
    发明申请
    Device with enhanced indication of use and prevention of re-use 审中-公开
    具有增强的使用指示和防止再次使用的装置

    公开(公告)号：US20060069305A1

    公开(公告)日：2006-03-30

    申请号：US10955905

    申请日：2004-09-30

    申请人： Lucien Couvillon ,  Sheng-Ping Zhong ,  Michael Banik ,  Ronald Sahatjian

    发明人： Lucien Couvillon ,  Sheng-Ping Zhong ,  Michael Banik ,  Ronald Sahatjian

    IPC分类号： A61B1/00 ,  A61B17/00

    CPC分类号： A61B1/00055 ,  A61B1/00062 ,  A61B1/00103 ,  A61B2090/0814 ,  A61B2560/0276

    摘要： In one aspect, the present invention is a medical device that reduces the likelihood of an operator improperly reusing it. The medical device includes (a) a device body; (b) a substrate comprising a contrast material that covers at least a portion of the device body; and (c) an outer layer comprising a hydrophilic material that covers at least a portion of the substrate. The outer layer comprising hydrophilic material is capable of absorbing water-soluble contaminants during clinical use that, once absorbed, are visible against the background of the substrate comprising the contrast material. In another aspect, the device includes (a) a device body and (b) an outer layer comprising a usage indicator reagent. In another aspect, the invention provides methods of preventing re-use of a single use medical device.

    摘要翻译： 一方面，本发明是减少操作者不当地重用它的可能性的医疗装置。 医疗装置包括（a）装置主体; （b）包括覆盖所述装置主体的至少一部分的对比材料的基板; 和（c）包含覆盖基材的至少一部分的亲水材料的外层。 包含亲水材料的外层能够在临床使用期间吸收水溶性污染物，其一旦被吸收就可以抵抗包含造影剂材料的底物的背景而可见。 在另一方面，该装置包括（a）装置主体和（b）包含使用指示剂试剂的外层。 在另一方面，本发明提供了防止单次使用的医疗装置的再次使用的方法。

    Polycarbonate-polyurethane dispersions for thrombo-resistant coatings
    27.
    发明授权
    Polycarbonate-polyurethane dispersions for thrombo-resistant coatings 有权
    用于抗血栓涂层的聚碳酸酯 - 聚氨酯分散体

    公开(公告)号：US06723121B1

    公开(公告)日：2004-04-20

    申请号：US09671418

    申请日：2000-09-27

    申请人： Sheng-Ping Zhong

    发明人： Sheng-Ping Zhong

    IPC分类号： A61F206

    CPC分类号： A61L33/062 ,  C08L75/04

    摘要： A coating for a medical device is described which enhances the bio-activity of the surface of a medical device, rendering the surface substantially bio-compatible. The bio-compatible coating is formed from a composition which includes an aqueous emulsion or dispersion of a polycarbonate-polyurethane composition and an excess of polyfunctional cross-linking agent.

    摘要翻译： 描述了用于医疗装置的涂层，其增强医疗装置的表面的生物活性，使得表面基本上与生物相容。 生物相容性涂层由包含聚碳酸酯 - 聚氨酯组合物和过量的多官能交联剂的水性乳液或分散体的组合物形成。

    Hydrophilic coating and substrates, particularly medical devices, provided with such a coating
    28.
    发明授权
    Hydrophilic coating and substrates, particularly medical devices, provided with such a coating 失效
    亲水涂层和基材，特别是医疗装置，具有这样的涂层

    公开(公告)号：US6048620A

    公开(公告)日：2000-04-11

    申请号：US929948

    申请日：1997-09-15

    申请人： Sheng-Ping Zhong

    发明人： Sheng-Ping Zhong

    IPC分类号： A61M25/00 ,  A61L29/00 ,  A61L29/08 ,  A61L29/16 ,  A61L31/00 ,  A61L31/16 ,  C03C17/32 ,  C08J7/04 ,  C08L33/02 ,  C08L75/00 ,  C08L75/04 ,  C09D201/00 ,  B32B27/00

    CPC分类号： A61L31/16 ,  A61L29/085 ,  A61L29/16 ,  A61L2300/21 ,  A61L2300/608 ,  A61L2420/08 ,  Y10T428/31565 ,  Y10T428/31573 ,  Y10T428/31576 ,  Y10T428/3158

    摘要： A substrate such as a catheter or a guide wire is provided with a lubricous, hydrophilic abrasion-resistant coating by:a) coating said substrate with a first aqueous coating composition comprising an aqueous dispersion or emulsion of a polymer having organic acid functional groups and a polyfunctional crosslinking agent having functional groups being capable of reacting with organic acid groups, and drying the coating to obtain a substantially water-insoluble coating layer still including functional groups being reactive with organic acid groups, andb) contacting the dried coating layer obtained in a) with a second aqueous coating composition comprising an aqueous solution or dispersion of a hydrophilic polymer having organic acid functional groups, and drying the combined coating, the hydrophilic polymer thereby becoming bonded to the polymer of the first coating composition through the crosslinking agent.The drying can be carried out at ambient (room) temperature.

    摘要翻译： 诸如导管或引导线之类的基材通过以下方式设置有润滑的亲水性耐磨涂层：a）用第一含水涂料组合物涂覆所述基材，所述第一水性涂料组合物包含具有有机酸官能团的聚合物的水性分散体或乳液，和 具有能够与有机酸基反应的官能团的多官能交联剂，干燥该涂层，得到仍含有与有机酸基反应的官能团的基本上不溶于水的涂层，以及b）使 ）与包含具有有机酸官能团的亲水聚合物的水溶液或分散体的第二水性涂料组合物，并干燥组合的涂层，亲水性聚合物因此通过交联剂与第一涂料组合物的聚合物结合。 干燥可在室温下进行。

    Expandable ablation burr
    30.
    发明授权
    Expandable ablation burr 失效
    可扩展消融毛刺

    公开(公告)号：US07252674B2

    公开(公告)日：2007-08-07

    申请号：US10770336

    申请日：2004-02-02

    申请人： Mark H. Wyzgala ,  Eric B. Hamilton ,  Tom J. Hiblar ,  Lixiao Wang ,  John J. Chen ,  Irina Nazarova ,  Nancy L. Haig ,  Sheng-Ping Zhong

    发明人： Mark H. Wyzgala ,  Eric B. Hamilton ,  Tom J. Hiblar ,  Lixiao Wang ,  John J. Chen ,  Irina Nazarova ,  Nancy L. Haig ,  Sheng-Ping Zhong

    IPC分类号： A61B17/32

    CPC分类号： A61B17/320725 ,  A61B17/320758 ,  A61B2017/00557 ,  A61B2017/00867 ,  A61B2017/320004 ,  A61B2017/320733

    摘要： An atherectomy burr has an operating diameter that is larger than the diameter of a catheter in which the burr is routed. The burr may include an expandable polymeric balloon having a partially abrasive exterior surface. The maximum expansion of the burr is controlled by an expansion mechanism. Various mechanisms are disclosed for controlling the maximum diameter of the burr thus preventing the burr from over expanding. In addition, the present invention includes systems that are pulled proximally to remove portions of a lesion located in a patient's vasculature. The system includes an ablation burr that has abrasive disposed on the proximal end. The burr may create a seal when expanded to block the ablated particulate so that an aspiration system can remove the particulate from the vasculature. Alternatively, the burr system may include a self expanding seal that is deployed out of the aspiration sheath.

    摘要翻译： 粥样斑块切除术毛刺的操作直径大于其中布置毛刺的导管的直径。 毛刺可以包括具有部分研磨外表面的可膨胀聚合气囊。 毛刺的最大膨胀由膨胀机构控制。 公开了用于控制毛刺的最大直径的各种机构，从而防止毛刺过度膨胀。 另外，本发明还包括向近侧拉动以去除位于病人脉管系统中的病变部分的系统。 该系统包括具有设置在近端的磨料的消融毛刺。 当膨胀时，毛刺可以产生密封，以阻止消融的颗粒，使得吸气系统可以从脉管系统中除去颗粒。 或者，毛刺系统可以包括从抽吸鞘部署出来的自膨胀密封件。