公开(公告)号：US20050186568A1

公开(公告)日：2005-08-25

申请号：US10491467

申请日：2002-10-17

Applicant: Olga Bandman ,  Mariah Baughn ,  Shanya Becha ,  Mark Borowsky ,  Brendan Duggan ,  Brooke Emerling ,  Ian Forsythe ,  Ameena Ganhi ,  Jennifer Griffin ,  Rajagopal Gururajan ,  April Hafalia ,  Farrah Khan ,  Preeti Lal ,  Ernestine Lee ,  Soo Lee ,  Erika Lindquist ,  Dyung Aina Lu ,  Yan Lu ,  Joseph Marquis ,  Danniel Nguyen ,  Chandra Arvizu ,  Jayalaxmi Ramkumar ,  Shirley Recipon ,  Thomas Richardson ,  Anita Swarnakar ,  Y.Tom Tang ,  Michael Thornton ,  Uyen Tran ,  Narinder Chawla ,  Bridget Warren ,  Junming Yang ,  Monique Yao ,  Henry Yue ,  Yeganeh Zebarjadian

Inventor： Olga Bandman ,  Mariah Baughn ,  Shanya Becha ,  Mark Borowsky ,  Brendan Duggan ,  Brooke Emerling ,  Ian Forsythe ,  Ameena Ganhi ,  Jennifer Griffin ,  Rajagopal Gururajan ,  April Hafalia ,  Farrah Khan ,  Preeti Lal ,  Ernestine Lee ,  Soo Lee ,  Erika Lindquist ,  Dyung Aina Lu ,  Yan Lu ,  Joseph Marquis ,  Danniel Nguyen ,  Chandra Arvizu ,  Jayalaxmi Ramkumar ,  Shirley Recipon ,  Thomas Richardson ,  Anita Swarnakar ,  Y.Tom Tang ,  Michael Thornton ,  Uyen Tran ,  Narinder Chawla ,  Bridget Warren ,  Junming Yang ,  Monique Yao ,  Henry Yue ,  Yeganeh Zebarjadian

IPC: G01N33/50 ,  A61K38/00 ,  A61K39/395 ,  A61K45/00 ,  A61K49/00 ,  A61P3/06 ,  A61P9/00 ,  A61P25/00 ,  A61P35/00 ,  A61P37/02 ,  A61P43/00 ,  C07H21/04 ,  C07K16/46 ,  C12M1/00 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/12 ,  C12N9/16 ,  C12N15/02 ,  C12N15/09 ,  C12P21/08 ,  C12Q1/42 ,  C12Q1/48 ,  C12Q1/68 ,  G01N33/15 ,  G01N33/53 ,  G01N37/00

CPC classification number: C12N9/1205 ,  A01K2217/05

Abstract: Various embodiments of the invention provide human kinases and phosphatases (KPP) and polynucleotides which identify and encode KPP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.

Abstract translation: 本发明的各种实施方案提供鉴定和编码KPP的人类激酶和磷酸酶（KPP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与KPP异常表达相关的紊乱的方法。

公开(公告)号：US20050164275A1

公开(公告)日：2005-07-28

申请号：US11048744

申请日：2005-02-03

Applicant: Michael Thornton ,  Li Ding ,  Chandra Arvizu ,  Monique Yao ,  Catherine Tribouley ,  Preeti Lal ,  April Hafalia ,  Mariah Baughn ,  Jayalaxmi Ramkumar ,  Yan Lu ,  Narinder Chawla

Inventor： Michael Thornton ,  Li Ding ,  Chandra Arvizu ,  Monique Yao ,  Catherine Tribouley ,  Preeti Lal ,  April Hafalia ,  Mariah Baughn ,  Jayalaxmi Ramkumar ,  Yan Lu ,  Narinder Chawla

IPC: A01K67/00 ,  C07H21/04 ,  C12N9/16 ,  C12Q1/68

CPC classification number: C12N9/16 ,  A01K2217/05

Abstract: The invention provides human phosphodiesterases (HPDE) and polynucleotides which identify and encode HPDE. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of HPDE.

公开(公告)号：US20050101529A1

公开(公告)日：2005-05-12

申请号：US10433757

申请日：2001-12-05

Applicant: Henry Yue ,  Yalda Azimzai ,  Deborah Kallick ,  Mariah Baughn ,  Jennifer Griffin ,  Anita Swarnakar ,  Preeti Lal ,  Narinder Chawla ,  April Hafalia ,  Ameena Gandhi ,  Janice Au-Young ,  Vicki Elliott ,  Jayalaxmi Ramkumar ,  Kavitha Thangavelu ,  Yan Lu ,  Bridget Warren ,  Dyung Lu ,  Ernestine Lee ,  Catherine Tribouley ,  Chandra Arvizu ,  Angelo Delegeane ,  Monique Yao ,  Farrah Khan ,  Madhusudan Sanjanwala

Inventor： Henry Yue ,  Yalda Azimzai ,  Deborah Kallick ,  Mariah Baughn ,  Jennifer Griffin ,  Anita Swarnakar ,  Preeti Lal ,  Narinder Chawla ,  April Hafalia ,  Ameena Gandhi ,  Janice Au-Young ,  Vicki Elliott ,  Jayalaxmi Ramkumar ,  Kavitha Thangavelu ,  Yan Lu ,  Bridget Warren ,  Dyung Lu ,  Ernestine Lee ,  Catherine Tribouley ,  Chandra Arvizu ,  Angelo Delegeane ,  Monique Yao ,  Farrah Khan ,  Madhusudan Sanjanwala

IPC: G01N33/50 ,  A61K38/00 ,  A61K45/00 ,  A61P1/00 ,  A61P1/04 ,  A61P1/08 ,  A61P1/14 ,  A61P1/16 ,  A61P1/18 ,  A61P3/06 ,  A61P7/02 ,  A61P9/00 ,  A61P9/10 ,  A61P9/12 ,  A61P11/06 ,  A61P13/12 ,  A61P15/00 ,  A61P17/00 ,  A61P17/06 ,  A61P17/08 ,  A61P19/02 ,  A61P19/10 ,  A61P21/04 ,  A61P25/00 ,  A61P25/14 ,  A61P25/16 ,  A61P25/18 ,  A61P29/00 ,  A61P31/18 ,  A61P35/00 ,  A61P35/02 ,  A61P37/06 ,  A61P37/08 ,  C07K1/14 ,  C07K14/47 ,  C07K16/40 ,  C07K16/46 ,  C12M1/00 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/12 ,  C12N9/16 ,  C12N9/50 ,  C12N9/64 ,  C12N9/76 ,  C12N15/09 ,  C12N15/12 ,  C12P21/08 ,  C12Q1/68 ,  G01N33/15 ,  G01N33/53 ,  G01N33/566

CPC classification number: C12N9/12 ,  C07K14/47 ,  C12N9/16 ,  C12N9/64

Abstract: The invention provides human protein modification and maintenance molecules (PMMM) and polynucleotides which identify and encode PMMM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMMM.

公开(公告)号：US06402195B1

公开(公告)日：2002-06-11

申请号：US09549571

申请日：2000-04-14

Applicant: Lutz Eisenmann ,  Yan Lu

Inventor： Lutz Eisenmann ,  Yan Lu

IPC: B60R2132

CPC classification number: B60N2/002 ,  B60N2/809 ,  B60N2002/0268

Abstract: In a device for adjusting a vehicle's head support with reference to the position of a passenger's head, with a sensor disposed in the head support for detecting the position of the head, the sensor contains two condenser plates which are arranged one above the other and are part of a condenser, in which the head of the passenger acts as a dielectric. In the method for the adjustment of the vehicle's head support, the height is varied, starting from a rest position with the head support retracted, to such an extent that the increase of the sensor signal of the one condenser plate takes place simultaneously with the decrease of the sensor signal of the other condenser plate.

Abstract translation: 在用于根据乘客头部的位置来调节车辆头部支撑的装置中，传感器设置在头部支撑件中，用于检测头部的位置，传感器包括两个彼此并排布置的电容器板 冷凝器的一部分，其中乘客的头部作为电介质。 在调整车辆头部支撑的方法中，高度随着头部支撑件缩回从静止位置开始变化，使得一个电容器板的传感器信号的增加与减少的同时发生 的另一个冷凝器板的传感器信号。

公开(公告)号：USD856978S1

公开(公告)日：2019-08-20

申请号：US29643095

申请日：2018-04-04

Applicant: Yan Lu

Designer： Yan Lu

公开(公告)号：USD836637S1

公开(公告)日：2018-12-25

申请号：US29599089

申请日：2017-03-30

Applicant: Yan Lu

Designer： Yan Lu

公开(公告)号：US10155728B2

公开(公告)日：2018-12-18

申请号：US15858183

申请日：2017-12-29

Applicant: Yan Lu ,  James T Dalton ,  Wei Li ,  Duane D Miller

Inventor： Yan Lu ,  James T Dalton ,  Wei Li ,  Duane D Miller

IPC: C07D401/02 ,  C07D401/10 ,  C07D401/14 ,  A61K31/437 ,  A61K31/4353 ,  C07D235/18 ,  A61K31/4184 ,  C07D403/04 ,  C07D417/12 ,  C07D471/04 ,  C07D277/24 ,  A61K31/426 ,  A61K45/06

Abstract: The present invention relates to colchicine-binding site compounds having anti-cancer activity, compositions comprising the same, and their use for treating various forms of cancer.

公开(公告)号：US09429921B2

公开(公告)日：2016-08-30

申请号：US14115888

申请日：2012-09-17

Applicant: Yan Lu ,  Ling Shen ,  Jianmin Zhu

Inventor： Yan Lu ,  Ling Shen ,  Jianmin Zhu

IPC: G05B13/04 ,  G06F17/50 ,  G06N3/12 ,  G06Q10/04 ,  G06Q50/06

CPC classification number: G05B13/04 ,  G06F17/5009 ,  G06N3/126 ,  G06Q10/04 ,  G06Q50/06

Abstract: In order to reduce computation time and cost involved with determining one or more optimal parameters for a pre-cooling strategy, for a modeled system, a two-step genetic algorithms is used to optimize energy consumption of the modeled system with respect to cost of the energy consumption. A first step of the two-step genetic algorithms determines a population of potential solutions that are used to initialize a second step of the two-step genetic algorithm. The second step of the two-step genetic algorithm determines the one or more optimal parameters for the pre-cooling strategy from the population output by the first genetic algorithm.

Abstract translation: 为了减少为预冷策略确定一个或多个最佳参数所涉及的计算时间和成本，对于建模的系统，使用两步遗传算法来优化建模系统的能耗相对于 能源消耗。 两步遗传算法的第一步确定了用于初始化两步遗传算法的第二步的潜在解的群体。 两步遗传算法的第二步确定了由第一遗传算法从群体输出中的预冷策略的一个或多个最优参数。

公开(公告)号：US08996037B2

公开(公告)日：2015-03-31

申请号：US13538780

申请日：2012-06-29

Applicant: Anning Chen ,  Vladimir Belov ,  Yan Lu ,  Alexander Makovskiy ,  Steven Malkos

Inventor： Anning Chen ,  Vladimir Belov ,  Yan Lu ,  Alexander Makovskiy ,  Steven Malkos

IPC: H04W24/00

CPC classification number: H04W64/00 ,  G01S5/0252

Abstract: A wireless communication device capable of determining its location in an indoor environment is disclosed. In an indoor environment, a wireless communication device may have insufficient access to GNSS satellites or cellular towers to make an accurate determination as to its location. Therefore, the wireless communication device generates a fingerprint map of the environment by estimating its position and scanning multiple positions within the environment for accessible access points and characteristics. The device stores this information in memory, which it can later refer to for determining its current position.

Abstract translation: 公开了能够确定其在室内环境中的位置的无线通信装置。 在室内环境中，无线通信设备可能不足以接入GNSS卫星或蜂窝塔，以便对其位置做出准确的确定。 因此，无线通信设备通过估计其位置并扫描环境内的可访问接入点和特性的多个位置来生成环境的指纹图。 该设备将该信息存储在存储器中，以后可以参考该信息来确定其当前位置。

公开(公告)号：US08719424B2

公开(公告)日：2014-05-06

申请号：US13383915

申请日：2010-05-18

Applicant: Yan Lu ,  Man Xie

Inventor： Yan Lu ,  Man Xie

IPC: G06F15/16 ,  H04L12/66

CPC classification number: H04L67/141 ,  H04L51/36 ,  H04L51/38 ,  H04L65/1006 ,  H04L67/143 ,  H04L69/08 ,  H04W4/12 ,  H04W4/18 ,  H04W80/04

Abstract: A transmission method and system for Converged IP Messaging (CPM) is disclosed, which can create Message Session Relay Protocol (MSRP) links between a CPM client and an originating participating function entity and between an Inter-Working Function entity (IWF) and the originating participating function entity respectively. The CPM client sends CPM message through each MSRP link to the inter-working function entity which sends the received CPM message to a non-CPM system after the protocol conversion of the CPM message. With the help of the method and system, the transmission link between the sender and the IWF is created by the session invite message of the large message mode CPM, and the content of the large message mode CPM is sent to the IWF which then transmits the content of the large message mode CPM to a non-CPM client of the receiver. The method and system resolves the problem that the content of the large message mode CPM can not be transmitted to a non-CPM system receiver in the prior art and improves the user experience.

Abstract translation: 公开了一种用于融合IP消息收发（CPM）的传输方法和系统，其可以在CPM客户端和始发参与功能实体之间以及在工作间功能实体（IWF）和始发端之间创建消息会话中继协议（MSRP）链路 参与功能实体。 CPM客户端通过每个MSRP链路将CPM消息发送到互通功能实体，其在CPM消息的协议转换之后将接收到的CPM消息发送到非CPM系统。 在方法和系统的帮助下，通过大消息模式CPM的会话邀请消息创建发送方和IWF之间的传输链路，并将大消息模式CPM的内容发送到IWF，然后IWF发送 大消息模式CPM的内容到接收者的非CPM客户端。 该方法和系统解决了现有技术中大消息模式CPM的内容不能传送到非CPM系统接收机的问题，并改善了用户体验。