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公开(公告)号：US20050164275A1
公开(公告)日：2005-07-28
申请号：US11048744
申请日：2005-02-03
申请人： Michael Thornton , Li Ding , Chandra Arvizu , Monique Yao , Catherine Tribouley , Preeti Lal , April Hafalia , Mariah Baughn , Jayalaxmi Ramkumar , Yan Lu , Narinder Chawla
发明人： Michael Thornton , Li Ding , Chandra Arvizu , Monique Yao , Catherine Tribouley , Preeti Lal , April Hafalia , Mariah Baughn , Jayalaxmi Ramkumar , Yan Lu , Narinder Chawla
CPC分类号： C12N9/16 , A01K2217/05
摘要： The invention provides human phosphodiesterases (HPDE) and polynucleotides which identify and encode HPDE. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of HPDE.
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公开(公告)号：US20050202478A1
公开(公告)日：2005-09-15
申请号：US11048068
申请日：2005-02-02
申请人： Michael Thornton , Li Ding , Chandra Arvizu , Monique Yao , Catherine Tribouley , Preeti Lal , April Hafalia , Mariah Baughn , Jayalaxmi Ramkumar , Yan Lu , Narinder Chawla
发明人： Michael Thornton , Li Ding , Chandra Arvizu , Monique Yao , Catherine Tribouley , Preeti Lal , April Hafalia , Mariah Baughn , Jayalaxmi Ramkumar , Yan Lu , Narinder Chawla
摘要： The invention provides human phosphodiesterases (HPDE) and polynucleotides which identify and encode HPDE. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of HPDE.
摘要翻译： 本发明提供了人类磷酸二酯酶（HPDE）和识别和编码HPDE的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与HPDE异常表达相关的疾病的方法。
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公开(公告)号：US20050239126A1
公开(公告)日：2005-10-27
申请号：US11167040
申请日：2005-06-27
申请人： Stephen Todd , Angelo Delegeane , Ameena Gandhi , Danniel Nguyen , April Hafalia , Liam Kearney , Yan Lu , Ernestine Lee , Narinder Chawla , Debopriya Das , Chandra Arvizu , Monique Yao , Deborah Kallick , Vicki Elliott , Li Ding , Henry Yue , Roopa Reddy , Dyung Lu , Jayalaxmi Ramkumar , Junming Yang , Catherine Tribouley , Neil Burford , Mariah Baughn , Preeti Lal , Mark Borowsky , Farrah Khan , Rajagopal Gururajan , Y. Tang , Janice Au-Young , Bridget Warren , Roberto Hernandez , Brendan Duggan
发明人： Stephen Todd , Angelo Delegeane , Ameena Gandhi , Danniel Nguyen , April Hafalia , Liam Kearney , Yan Lu , Ernestine Lee , Narinder Chawla , Debopriya Das , Chandra Arvizu , Monique Yao , Deborah Kallick , Vicki Elliott , Li Ding , Henry Yue , Roopa Reddy , Dyung Lu , Jayalaxmi Ramkumar , Junming Yang , Catherine Tribouley , Neil Burford , Mariah Baughn , Preeti Lal , Mark Borowsky , Farrah Khan , Rajagopal Gururajan , Y. Tang , Janice Au-Young , Bridget Warren , Roberto Hernandez , Brendan Duggan
CPC分类号： C12N9/6421 , A01K2217/05 , A01K2217/075 , C07H21/04 , C12N9/6472 , C12Q1/6837 , C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , Y02A50/52
摘要： The invention provides human proteases (PRTS) and polynucleotides which identify and encode PRTS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PRTS.
摘要翻译： 本发明提供鉴定和编码PRTS的人类蛋白酶（PRTS）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供诊断，治疗或预防与PRTS异常表达相关的疾病的方法。
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公开(公告)号：US20060194275A1
公开(公告)日：2006-08-31
申请号：US10474894
申请日：2002-04-12
申请人： Mariah Baughn , Vicki Elliott , April Hafalia , Junming Yang , Narinder Chawla , Jayalaxmi Ramkumar , Ian Forsythe , Yan Lu , Y Tom Tang , Henry Yue , Brigitte Raumann , Preeti Lal , Yalda Azimzai , Dyung Lu , Ameena Gandhi , Michael Thornton , Danniel Nguyen , Chandra Arvizu , Brooke Emerling , Anita Swarnakar , Monique Yao , Li Ding , Ann He , Jennifer Griffin , Madhusudan Sanjanwala , Kimberly Gietzen , Ernestine Lee , Yuming Xu , Janice Au-Young , Debopriya Das , Soo Lee , Hsin-Ru Chang
发明人： Mariah Baughn , Vicki Elliott , April Hafalia , Junming Yang , Narinder Chawla , Jayalaxmi Ramkumar , Ian Forsythe , Yan Lu , Y Tom Tang , Henry Yue , Brigitte Raumann , Preeti Lal , Yalda Azimzai , Dyung Lu , Ameena Gandhi , Michael Thornton , Danniel Nguyen , Chandra Arvizu , Brooke Emerling , Anita Swarnakar , Monique Yao , Li Ding , Ann He , Jennifer Griffin , Madhusudan Sanjanwala , Kimberly Gietzen , Ernestine Lee , Yuming Xu , Janice Au-Young , Debopriya Das , Soo Lee , Hsin-Ru Chang
IPC分类号： C07K14/705 , C07H21/04 , C12P21/06
CPC分类号： C12Q1/6886 , A61K31/706 , A61K38/00 , A61K48/00 , C07K14/4703 , C12Q1/683 , C12Q1/6858 , C12Q2600/154 , C12Q2600/158 , C12Q2521/331 , C12Q2531/113 , C12Q2523/125
摘要： The invention provides human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.
摘要翻译： 本发明提供了识别和编码TRICH的人转运体和离子通道（TRICH）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与TRICH异常表达相关的紊乱的方法。
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公开(公告)号：US20050118582A1
公开(公告)日：2005-06-02
申请号：US10483505
申请日：2002-07-10
申请人： Anita Swarnakar , Thomas Richardson , Bridget Warren , Jennifer Griffin , Y Tang , Henry Yue , Mariah Baughn , Brooke Emerling , Preeti Lal , Dyung Lu , Ian Forsythe , Jayalaxmi Ramkumar , Joana Li , Shanya Becha , Brendan Duggan , Madhusudan Sanjanwala , Ernestine Lee , Neil Burford , Vicki Elliott , Craig Ison , Li Ding , Mark Borowsky , Monique Yao , Ines Barroso , Bao Tran , Narinder Chawla , April Hafalia , Danniel Nguyen , Yan Lu , Chandra Arvizu
发明人： Anita Swarnakar , Thomas Richardson , Bridget Warren , Jennifer Griffin , Y Tang , Henry Yue , Mariah Baughn , Brooke Emerling , Preeti Lal , Dyung Lu , Ian Forsythe , Jayalaxmi Ramkumar , Joana Li , Shanya Becha , Brendan Duggan , Madhusudan Sanjanwala , Ernestine Lee , Neil Burford , Vicki Elliott , Craig Ison , Li Ding , Mark Borowsky , Monique Yao , Ines Barroso , Bao Tran , Narinder Chawla , April Hafalia , Danniel Nguyen , Yan Lu , Chandra Arvizu
CPC分类号： C07K14/4702
摘要： Various embodiments of the invention provide human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.
摘要翻译： 本发明的各种实施方案提供了识别和编码NAAP的人核酸相关蛋白（NAAP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与NAAP异常表达相关的紊乱的方法。
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公开(公告)号：US20050142600A1
公开(公告)日：2005-06-30
申请号：US11046868
申请日：2005-02-01
申请人： Bridget Warren , Cynthia Honchell , Yan Lu , Narinder Chawla , Neil Burford , Angelo Delegeane , Ameena Gandhi , Mariah Baughn , Jennifer Griffin , Kimberly Gietzen , Dyung Lu , Craig Ison , Jayalaxmi Ramkumar , Y. Tang , Preeti Lal , Mark Borowsky , Brendan Duggan , April Hafalia , Chandra Arvizu , Kavitha Thangavelu , Monique Yao , Vicki Elliott , Li Ding , Henry Yue , Sally Lee , Anita Swarnakar , Uyen Tran , Yuming Xu
发明人： Bridget Warren , Cynthia Honchell , Yan Lu , Narinder Chawla , Neil Burford , Angelo Delegeane , Ameena Gandhi , Mariah Baughn , Jennifer Griffin , Kimberly Gietzen , Dyung Lu , Craig Ison , Jayalaxmi Ramkumar , Y. Tang , Preeti Lal , Mark Borowsky , Brendan Duggan , April Hafalia , Chandra Arvizu , Kavitha Thangavelu , Monique Yao , Vicki Elliott , Li Ding , Henry Yue , Sally Lee , Anita Swarnakar , Uyen Tran , Yuming Xu
CPC分类号： C12N9/6421 , A01K2217/05 , A61K38/00 , C07H21/04 , C12N9/64
摘要： The invention provides human protein modification and maintenance molecules (PMMM) and polynucleotides which identify and encode PMMM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMMM.
摘要翻译： 本发明提供了鉴定和编码PMMM的人蛋白质修饰和维持分子（PMMM）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与PMMM的异常表达相关的紊乱的方法。
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公开(公告)号：US20050176927A1
公开(公告)日：2005-08-11
申请号：US10450186
申请日：2001-12-12
申请人： Jennifer Griffin , Monique Yao , Brendan Duggan , Henry Yue , Li Ding , Preeti Lal , Ernestine Lee , Jayalaxmi Ramkumar , Kavitha Thangavelu , Yuming Xu , Sally Lee , Y. Tang , Danniel Nguyen , Bridget Warren , Cynthia Honchell , Kimberly Gietzen , Mariah Baughn , Ameena Gandhi , Chandra Arvizu , Narinder Chawla , Yan Lu , Vicki Elliott , Dyung Lu , April J A Hafalia , Yalda Azimzai , Farrah Khan , Uyen Tran
发明人： Jennifer Griffin , Monique Yao , Brendan Duggan , Henry Yue , Li Ding , Preeti Lal , Ernestine Lee , Jayalaxmi Ramkumar , Kavitha Thangavelu , Yuming Xu , Sally Lee , Y. Tang , Danniel Nguyen , Bridget Warren , Cynthia Honchell , Kimberly Gietzen , Mariah Baughn , Ameena Gandhi , Chandra Arvizu , Narinder Chawla , Yan Lu , Vicki Elliott , Dyung Lu , April J A Hafalia , Yalda Azimzai , Farrah Khan , Uyen Tran
IPC分类号： G01N33/50 , A61K38/00 , A61K45/00 , A61P1/04 , A61P1/16 , A61P1/18 , A61P3/00 , A61P3/10 , A61P5/14 , A61P5/38 , A61P7/00 , A61P7/02 , A61P7/06 , A61P7/08 , A61P9/00 , A61P9/04 , A61P9/10 , A61P9/12 , A61P11/00 , A61P11/06 , A61P13/02 , A61P13/12 , A61P15/00 , A61P17/00 , A61P17/02 , A61P17/04 , A61P17/06 , A61P17/16 , A61P19/00 , A61P19/02 , A61P19/04 , A61P19/06 , A61P19/10 , A61P21/00 , A61P21/04 , A61P25/00 , A61P25/02 , A61P25/04 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/20 , A61P25/22 , A61P25/28 , A61P27/02 , A61P27/06 , A61P27/12 , A61P29/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P31/18 , A61P33/00 , A61P33/02 , A61P35/00 , A61P35/02 , A61P37/00 , A61P37/08 , A61P39/00 , A61P41/00 , A61P43/00 , C07K14/47 , C07K16/18 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12P21/02 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566
CPC分类号： C07K14/47 , A01K2217/05 , A61K38/00 , A61K2039/505 , C07K2317/24
摘要： The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
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公开(公告)号：US20070092885A1
公开(公告)日：2007-04-26
申请号：US11378616
申请日：2006-03-20
申请人： Henry Yue , Monique Yao , Ameena Gandhi , Mariah Baughn , Anita Swarnakar , Narinder Chawla , Madhusudan Sanjanwala , Michael Thornton , Vicki Elliott , Yan Lu , Kimberly Gietzen , Neil Burford , Li Ding , April Hafalia , Y. Tang , Olga Bandman , Bridget Warren , Cynthia Honchell , Dyung Lu , Kavitha Thangavelu , Sally Lee , Yuming Xu , Junming Yang , Preeti Lal , Bao Tran , Craig Ison , Brendan Duggan , Stephanie Sapperstein
发明人： Henry Yue , Monique Yao , Ameena Gandhi , Mariah Baughn , Anita Swarnakar , Narinder Chawla , Madhusudan Sanjanwala , Michael Thornton , Vicki Elliott , Yan Lu , Kimberly Gietzen , Neil Burford , Li Ding , April Hafalia , Y. Tang , Olga Bandman , Bridget Warren , Cynthia Honchell , Dyung Lu , Kavitha Thangavelu , Sally Lee , Yuming Xu , Junming Yang , Preeti Lal , Bao Tran , Craig Ison , Brendan Duggan , Stephanie Sapperstein
CPC分类号： C12N15/1055 , A61K39/3955 , A61K47/64 , A61K47/643 , A61K2039/505 , C07K14/47 , C07K14/4711 , C07K14/4713 , C07K16/18 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/622 , C07K2317/75 , C07K2317/76 , G01N33/5023
摘要： The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
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公开(公告)号：US20050176944A1
公开(公告)日：2005-08-11
申请号：US10487092
申请日：2002-08-16
申请人： Henry Yue , Dyung Lu , Anita Swarnakar , Y. Tang , Jennifer Griffin , Brooke Emerling , Ian Forsythe , Monique Yao , Jayalaxmi Ramkumar , Thomas Richardson , Shanya Becha , Ernestine Lee , Bridget Warren , Patricia Lehr-Mason , Mariah Baughn , Joana Li , Brendan Duggan , Kimberly Gietzen , Preeti Lal , Mark Borowsky , Craig Ison , Kavitha Thangavelu , Yuming Xu , Sally Lee , Vicki Elliott , William Sprague , Yalda Azimzai , April Hafalia , Li Ding , Danniel Nguyen , Cynthia Honchell , Wen Luo , Narinder Chawla , Joseph Marquis , Jennifer Jackson , Uyen Tran
发明人： Henry Yue , Dyung Lu , Anita Swarnakar , Y. Tang , Jennifer Griffin , Brooke Emerling , Ian Forsythe , Monique Yao , Jayalaxmi Ramkumar , Thomas Richardson , Shanya Becha , Ernestine Lee , Bridget Warren , Patricia Lehr-Mason , Mariah Baughn , Joana Li , Brendan Duggan , Kimberly Gietzen , Preeti Lal , Mark Borowsky , Craig Ison , Kavitha Thangavelu , Yuming Xu , Sally Lee , Vicki Elliott , William Sprague , Yalda Azimzai , April Hafalia , Li Ding , Danniel Nguyen , Cynthia Honchell , Wen Luo , Narinder Chawla , Joseph Marquis , Jennifer Jackson , Uyen Tran
IPC分类号： G01N33/50 , A61K38/00 , A61K39/395 , A61K45/00 , A61K49/00 , A61P1/00 , A61P5/00 , A61P5/14 , A61P15/00 , A61P25/00 , A61P29/00 , A61P35/00 , A61P37/06 , C07H21/04 , C07K1/22 , C07K14/47 , C07K16/18 , C07K16/46 , C12M1/00 , C12M1/34 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/02 , C12N9/12 , C12N9/14 , C12N9/16 , C12N15/02 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/00 , C12Q1/32 , C12Q1/34 , C12Q1/42 , C12Q1/48 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00
CPC分类号： C07K14/4702 , A61K38/00 , C07K14/47 , G01N2500/04
摘要： Various embodiments of the invention provide human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INTSIG.
摘要翻译： 本发明的各种实施方案提供了识别和编码INTSIG的人细胞内信号分子（INTSIG）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与INTSIG的异常表达相关的紊乱的方法。
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公开(公告)号：US20050112745A1
公开(公告)日：2005-05-26
申请号：US10976440
申请日：2004-10-29
申请人： Preeti Lal , Y. Tang , Henry Yue , Neil Burford , Ameena Gandhi , Bridget Warren , Monique Yao , Catherine Tribouley , Mariah Baughn , Ernestine Lee , April Hafalia , Yan Lu , Jennifer Griffin , Madhusudan Sanjanwala , Li Ding
发明人： Preeti Lal , Y. Tang , Henry Yue , Neil Burford , Ameena Gandhi , Bridget Warren , Monique Yao , Catherine Tribouley , Mariah Baughn , Ernestine Lee , April Hafalia , Yan Lu , Jennifer Griffin , Madhusudan Sanjanwala , Li Ding
CPC分类号： C12N9/10 , A61K38/00 , A61K48/00 , B01J2219/00659 , B01J2219/00702 , B01J2219/00725 , C40B40/10
摘要： The invention provides human transferases (TRNFR) and polynucleotides which identify and encode TRNFR. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRNFR.
摘要翻译： 本发明提供鉴定和编码TRNFR的人转移酶（TRNFR）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与TRNFR异常表达相关的紊乱的方法。
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