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公开(公告)号：US20070009886A1
公开(公告)日：2007-01-11
申请号：US10534578
申请日：2003-11-10
申请人： Narinder Chawla , Y. Tom Tang , Jennifer Griffin , Yonghong Yang , Jayalaxmi Ramkumar , Reena Khare , Thomas Richardson , Shanya Becha , Uyen Tran , Amy Kable , Anita Swarnakar , Bridget Warren , Vicki Elliott , Joseph Marquis , April Hafalia
发明人： Narinder Chawla , Y. Tom Tang , Jennifer Griffin , Yonghong Yang , Jayalaxmi Ramkumar , Reena Khare , Thomas Richardson , Shanya Becha , Uyen Tran , Amy Kable , Anita Swarnakar , Bridget Warren , Vicki Elliott , Joseph Marquis , April Hafalia
CPC分类号： C07K14/47 , C07K14/4726
摘要： Various embodiments of the invention provide human carbohydrate-associated proteins (CHOP) and polynucleotides which identify and encode CHOP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CHOP.
摘要翻译： 本发明的各种实施方案提供了识别和编码CHOP的人碳水化合物相关蛋白（CHOP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与CHOP异常表达相关的障碍的方法。
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公开(公告)号：US20050186568A1
公开(公告)日：2005-08-25
申请号：US10491467
申请日：2002-10-17
申请人： Olga Bandman , Mariah Baughn , Shanya Becha , Mark Borowsky , Brendan Duggan , Brooke Emerling , Ian Forsythe , Ameena Ganhi , Jennifer Griffin , Rajagopal Gururajan , April Hafalia , Farrah Khan , Preeti Lal , Ernestine Lee , Soo Lee , Erika Lindquist , Dyung Aina Lu , Yan Lu , Joseph Marquis , Danniel Nguyen , Chandra Arvizu , Jayalaxmi Ramkumar , Shirley Recipon , Thomas Richardson , Anita Swarnakar , Y.Tom Tang , Michael Thornton , Uyen Tran , Narinder Chawla , Bridget Warren , Junming Yang , Monique Yao , Henry Yue , Yeganeh Zebarjadian
发明人： Olga Bandman , Mariah Baughn , Shanya Becha , Mark Borowsky , Brendan Duggan , Brooke Emerling , Ian Forsythe , Ameena Ganhi , Jennifer Griffin , Rajagopal Gururajan , April Hafalia , Farrah Khan , Preeti Lal , Ernestine Lee , Soo Lee , Erika Lindquist , Dyung Aina Lu , Yan Lu , Joseph Marquis , Danniel Nguyen , Chandra Arvizu , Jayalaxmi Ramkumar , Shirley Recipon , Thomas Richardson , Anita Swarnakar , Y.Tom Tang , Michael Thornton , Uyen Tran , Narinder Chawla , Bridget Warren , Junming Yang , Monique Yao , Henry Yue , Yeganeh Zebarjadian
IPC分类号： G01N33/50 , A61K38/00 , A61K39/395 , A61K45/00 , A61K49/00 , A61P3/06 , A61P9/00 , A61P25/00 , A61P35/00 , A61P37/02 , A61P43/00 , C07H21/04 , C07K16/46 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/12 , C12N9/16 , C12N15/02 , C12N15/09 , C12P21/08 , C12Q1/42 , C12Q1/48 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00
CPC分类号： C12N9/1205 , A01K2217/05
摘要： Various embodiments of the invention provide human kinases and phosphatases (KPP) and polynucleotides which identify and encode KPP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.
摘要翻译： 本发明的各种实施方案提供鉴定和编码KPP的人类激酶和磷酸酶（KPP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与KPP异常表达相关的紊乱的方法。
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公开(公告)号：US20050176944A1
公开(公告)日：2005-08-11
申请号：US10487092
申请日：2002-08-16
申请人： Henry Yue , Dyung Lu , Anita Swarnakar , Y. Tang , Jennifer Griffin , Brooke Emerling , Ian Forsythe , Monique Yao , Jayalaxmi Ramkumar , Thomas Richardson , Shanya Becha , Ernestine Lee , Bridget Warren , Patricia Lehr-Mason , Mariah Baughn , Joana Li , Brendan Duggan , Kimberly Gietzen , Preeti Lal , Mark Borowsky , Craig Ison , Kavitha Thangavelu , Yuming Xu , Sally Lee , Vicki Elliott , William Sprague , Yalda Azimzai , April Hafalia , Li Ding , Danniel Nguyen , Cynthia Honchell , Wen Luo , Narinder Chawla , Joseph Marquis , Jennifer Jackson , Uyen Tran
发明人： Henry Yue , Dyung Lu , Anita Swarnakar , Y. Tang , Jennifer Griffin , Brooke Emerling , Ian Forsythe , Monique Yao , Jayalaxmi Ramkumar , Thomas Richardson , Shanya Becha , Ernestine Lee , Bridget Warren , Patricia Lehr-Mason , Mariah Baughn , Joana Li , Brendan Duggan , Kimberly Gietzen , Preeti Lal , Mark Borowsky , Craig Ison , Kavitha Thangavelu , Yuming Xu , Sally Lee , Vicki Elliott , William Sprague , Yalda Azimzai , April Hafalia , Li Ding , Danniel Nguyen , Cynthia Honchell , Wen Luo , Narinder Chawla , Joseph Marquis , Jennifer Jackson , Uyen Tran
IPC分类号： G01N33/50 , A61K38/00 , A61K39/395 , A61K45/00 , A61K49/00 , A61P1/00 , A61P5/00 , A61P5/14 , A61P15/00 , A61P25/00 , A61P29/00 , A61P35/00 , A61P37/06 , C07H21/04 , C07K1/22 , C07K14/47 , C07K16/18 , C07K16/46 , C12M1/00 , C12M1/34 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/02 , C12N9/12 , C12N9/14 , C12N9/16 , C12N15/02 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/00 , C12Q1/32 , C12Q1/34 , C12Q1/42 , C12Q1/48 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00
CPC分类号： C07K14/4702 , A61K38/00 , C07K14/47 , G01N2500/04
摘要： Various embodiments of the invention provide human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INTSIG.
摘要翻译： 本发明的各种实施方案提供了识别和编码INTSIG的人细胞内信号分子（INTSIG）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与INTSIG的异常表达相关的紊乱的方法。
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公开(公告)号：US20050130145A1
公开(公告)日：2005-06-16
申请号：US10491355
申请日：2002-10-03
申请人： Henry Yue , Bridget Warren , Patricia Lehr-Mason , Uyen Tran , Brendan Duggan , Kavitha Thangavelu , Junming Yang , Yuming Xu , Y. Tang , Narinder Chawla , Vicki Elliott , Ian Forsythe , Shanya Becha , Monique Yao , Brooke Emerling , Jennifer Griffin , Preeti Lal , Yeganeh Zebarjadian , Mariah Baughn , Ernestine Lee , Soo Lee , Jayalaxmi Ramkumar , Ann Gorvad , Amy Kable , Dyung Lu , Mark Borowsky
发明人： Henry Yue , Bridget Warren , Patricia Lehr-Mason , Uyen Tran , Brendan Duggan , Kavitha Thangavelu , Junming Yang , Yuming Xu , Y. Tang , Narinder Chawla , Vicki Elliott , Ian Forsythe , Shanya Becha , Monique Yao , Brooke Emerling , Jennifer Griffin , Preeti Lal , Yeganeh Zebarjadian , Mariah Baughn , Ernestine Lee , Soo Lee , Jayalaxmi Ramkumar , Ann Gorvad , Amy Kable , Dyung Lu , Mark Borowsky
IPC分类号： A01K67/027 , A61K38/00 , A61K45/00 , A61P1/00 , A61P1/04 , A61P1/16 , A61P1/18 , A61P3/10 , A61P5/00 , A61P7/00 , A61P7/02 , A61P7/04 , A61P7/06 , A61P9/04 , A61P9/08 , A61P9/10 , A61P9/12 , A61P11/00 , A61P11/06 , A61P13/12 , A61P17/00 , A61P17/02 , A61P19/00 , A61P19/02 , A61P19/06 , A61P19/10 , A61P21/04 , A61P25/00 , A61P25/02 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/20 , A61P25/28 , A61P29/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P31/18 , A61P33/00 , A61P35/00 , A61P37/02 , A61P37/08 , C07K14/47 , C07K16/18 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/64 , C12N15/02 , C12N15/09 , C12N15/12 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/50 , G01N33/53 , G01N33/566 , G01N37/00 , A61K38/17 , C07H21/04 , C12N9/00
CPC分类号： C07K14/47 , A01K2217/05 , C12N9/6421
摘要： Various embodiments of the invention provide human secreted proteins (SECP) and polynucleotides which identify and encode SECP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
摘要翻译： 本发明的各种实施方案提供鉴定和编码SECP的人分泌蛋白（SECP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其它实施方案提供用于诊断，治疗或预防与SECP异常表达相关的疾病的方法。
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公开(公告)号：US20050107588A1
公开(公告)日：2005-05-19
申请号：US10495148
申请日：2002-11-13
申请人： Brendan Duggan , Junming Yang , Kimberly Gietzen , Soo Lee , Y. Tang , Yalda Azimzai , Narinder Chawla , Bridget Warren , Ines Barroso , Shanya Becha , Henry Yue , Patricia Lehr-Mason , Kavitha Thangavelu , Sally Lee , Brooke Emerling , Amy Kable , Reena Khare , Mariah Baughn , Ameena Gandhi , Uyen Tran , Thomas Richardson , Joseph Marquis , Preeti Lal , Ian Forsythe , Ernestine Lee , Anita Swarnakar , Deborah Kallick , Jennifer Griffin , Vicki Elliott , Ann Gorvad , April Hafalia , Craig Ison , Pei Jin , Xin Jiang , Alan Jackson , Umesh Bhatia , John Burrill , Julie Blake , Anne Ho , Wenjin Zheng , Jing Gao
发明人： Brendan Duggan , Junming Yang , Kimberly Gietzen , Soo Lee , Y. Tang , Yalda Azimzai , Narinder Chawla , Bridget Warren , Ines Barroso , Shanya Becha , Henry Yue , Patricia Lehr-Mason , Kavitha Thangavelu , Sally Lee , Brooke Emerling , Amy Kable , Reena Khare , Mariah Baughn , Ameena Gandhi , Uyen Tran , Thomas Richardson , Joseph Marquis , Preeti Lal , Ian Forsythe , Ernestine Lee , Anita Swarnakar , Deborah Kallick , Jennifer Griffin , Vicki Elliott , Ann Gorvad , April Hafalia , Craig Ison , Pei Jin , Xin Jiang , Alan Jackson , Umesh Bhatia , John Burrill , Julie Blake , Anne Ho , Wenjin Zheng , Jing Gao
IPC分类号： C07K14/47 , C07K14/705 , C07H21/04
CPC分类号： C07K14/705 , C07K14/47
摘要： Various embodiments of the invention provide human receptors and membrane-associated proteins (REMAP) and polynucleotides which identify and encode REMAP. Embodiments of the invention also provide expression vectors, host cells, anti-bodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.
摘要翻译： 本发明的各种实施方案提供了识别和编码REMAP的人受体和膜相关蛋白（REMAP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与REMAP异常表达相关的紊乱的方法。
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公开(公告)号：US20050101529A1
公开(公告)日：2005-05-12
申请号：US10433757
申请日：2001-12-05
申请人： Henry Yue , Yalda Azimzai , Deborah Kallick , Mariah Baughn , Jennifer Griffin , Anita Swarnakar , Preeti Lal , Narinder Chawla , April Hafalia , Ameena Gandhi , Janice Au-Young , Vicki Elliott , Jayalaxmi Ramkumar , Kavitha Thangavelu , Yan Lu , Bridget Warren , Dyung Lu , Ernestine Lee , Catherine Tribouley , Chandra Arvizu , Angelo Delegeane , Monique Yao , Farrah Khan , Madhusudan Sanjanwala
发明人： Henry Yue , Yalda Azimzai , Deborah Kallick , Mariah Baughn , Jennifer Griffin , Anita Swarnakar , Preeti Lal , Narinder Chawla , April Hafalia , Ameena Gandhi , Janice Au-Young , Vicki Elliott , Jayalaxmi Ramkumar , Kavitha Thangavelu , Yan Lu , Bridget Warren , Dyung Lu , Ernestine Lee , Catherine Tribouley , Chandra Arvizu , Angelo Delegeane , Monique Yao , Farrah Khan , Madhusudan Sanjanwala
IPC分类号： G01N33/50 , A61K38/00 , A61K45/00 , A61P1/00 , A61P1/04 , A61P1/08 , A61P1/14 , A61P1/16 , A61P1/18 , A61P3/06 , A61P7/02 , A61P9/00 , A61P9/10 , A61P9/12 , A61P11/06 , A61P13/12 , A61P15/00 , A61P17/00 , A61P17/06 , A61P17/08 , A61P19/02 , A61P19/10 , A61P21/04 , A61P25/00 , A61P25/14 , A61P25/16 , A61P25/18 , A61P29/00 , A61P31/18 , A61P35/00 , A61P35/02 , A61P37/06 , A61P37/08 , C07K1/14 , C07K14/47 , C07K16/40 , C07K16/46 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/12 , C12N9/16 , C12N9/50 , C12N9/64 , C12N9/76 , C12N15/09 , C12N15/12 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566
摘要： The invention provides human protein modification and maintenance molecules (PMMM) and polynucleotides which identify and encode PMMM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMMM.
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公开(公告)号：US20050069878A1
公开(公告)日：2005-03-31
申请号：US10481041
申请日：2002-06-12
申请人： Henry Yue , Dyung Lu , April Hafalia , Chandra Arvizu , Jayalaxmi Ramkumar , Y Tang , Farrah Khan , Barrie Greene , Thomas Richardson , Junming Yang , Craig Ison , Bridget Warren , Vicki Elliott , Brooke Emerling , Ann Gorvard , Ernestine Lee , Jennifer Griffin , Yeganeh Zebarjadian , Anita Swarnakar , Preeti Lal , Mariah Baughn , Uyen Tran , Sally Lee , Ian Forsythe , Janice Au-Young
发明人： Henry Yue , Dyung Lu , April Hafalia , Chandra Arvizu , Jayalaxmi Ramkumar , Y Tang , Farrah Khan , Barrie Greene , Thomas Richardson , Junming Yang , Craig Ison , Bridget Warren , Vicki Elliott , Brooke Emerling , Ann Gorvard , Ernestine Lee , Jennifer Griffin , Yeganeh Zebarjadian , Anita Swarnakar , Preeti Lal , Mariah Baughn , Uyen Tran , Sally Lee , Ian Forsythe , Janice Au-Young
IPC分类号： G01N33/50 , A01K67/00 , A61K38/00 , A61K39/395 , A61K45/00 , A61K48/00 , A61P1/16 , A61P3/10 , A61P7/06 , A61P9/10 , A61P11/00 , A61P11/06 , A61P15/00 , A61P15/10 , A61P17/06 , A61P19/00 , A61P19/02 , A61P19/06 , A61P21/00 , A61P25/00 , A61P25/08 , A61P25/16 , A61P25/20 , A61P25/28 , A61P27/06 , A61P27/12 , A61P29/00 , A61P31/04 , A61P31/12 , A61P31/18 , A61P33/00 , A61P35/00 , A61P35/02 , A61P37/00 , A61P37/08 , C07H21/04 , C07K1/14 , C07K14/47 , C07K14/475 , C07K16/18 , C07K16/46 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/64 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53
CPC分类号： C07K14/4702 , A01K2217/05 , A61K38/00 , C07K14/4747
摘要： Various embodiments of the invention provide human proteins associated with cell growth, differentiation, and death (CGDD) and polynucleotides which identify and encode CGDD. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CGDD.
摘要翻译： 本发明的各种实施方案提供与细胞生长，分化和死亡（CGDD）相关的人类蛋白质和鉴定和编码CGDD的多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与CGDD异常表达相关的紊乱的方法。
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公开(公告)号：US20170344698A1
公开(公告)日：2017-11-30
申请号：US15530849
申请日：2017-03-08
申请人： Jennifer Griffin
发明人： Jennifer Griffin
摘要： A repeatable methodology for generation of a specific biological function library (data pool) and techniques for structuring queries that cluster and parse gene and protein alterations in individual patients and patient cohorts. Method enables analytical distinction between detectable changes in biological function and non-detectable changes in biological function using current diagnostic techniques and technologies.
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公开(公告)号：US20060216706A1
公开(公告)日：2006-09-28
申请号：US10484603
申请日：2002-07-16
申请人： Y Tang , Vicki Elliott , Mariah Baughn , Henry Yue , Aaron Klammer , April Hafalia , Elizabeth Stewart , Cynthia Honchell , Ann Gorvard , Ian Forsythe , Li Ding , Uyen Tran , Jennifer Griffin , Yeganeh Zebarjadian , Anna Chinn , Anne Curtis , Mark Borowsky , Anita Swarnakar , Neil Burford , Wen Luo , Ernestine Lee , Brooke Emerling , Soo Lee , Junming Yang , Farrah Khan , Jayalaxmi Ramkumar , Yan Lu , Narinder Chawla , Brendan Duggan , Kimberly Gietzen , Karen Jones
发明人： Y Tang , Vicki Elliott , Mariah Baughn , Henry Yue , Aaron Klammer , April Hafalia , Elizabeth Stewart , Cynthia Honchell , Ann Gorvard , Ian Forsythe , Li Ding , Uyen Tran , Jennifer Griffin , Yeganeh Zebarjadian , Anna Chinn , Anne Curtis , Mark Borowsky , Anita Swarnakar , Neil Burford , Wen Luo , Ernestine Lee , Brooke Emerling , Soo Lee , Junming Yang , Farrah Khan , Jayalaxmi Ramkumar , Yan Lu , Narinder Chawla , Brendan Duggan , Kimberly Gietzen , Karen Jones
IPC分类号： C12Q1/68 , G01N33/574 , C07H21/04 , C12P21/06 , C07K14/705
CPC分类号： C07K14/47 , C12Q1/6883 , C12Q1/6886 , C12Q2600/136 , G01N33/574 , G01N2510/00
摘要： Various embodiments of the invention provide human proteins associated with cell growth, differentiation, and death (CGDD) and polynucleotides which identify and encode CGDD. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CGDD.
摘要翻译： 本发明的各种实施方案提供与细胞生长，分化和死亡（CGDD）相关的人类蛋白质和鉴定和编码CGDD的多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与CGDD异常表达相关的紊乱的方法。
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公开(公告)号：US20060194275A1
公开(公告)日：2006-08-31
申请号：US10474894
申请日：2002-04-12
申请人： Mariah Baughn , Vicki Elliott , April Hafalia , Junming Yang , Narinder Chawla , Jayalaxmi Ramkumar , Ian Forsythe , Yan Lu , Y Tom Tang , Henry Yue , Brigitte Raumann , Preeti Lal , Yalda Azimzai , Dyung Lu , Ameena Gandhi , Michael Thornton , Danniel Nguyen , Chandra Arvizu , Brooke Emerling , Anita Swarnakar , Monique Yao , Li Ding , Ann He , Jennifer Griffin , Madhusudan Sanjanwala , Kimberly Gietzen , Ernestine Lee , Yuming Xu , Janice Au-Young , Debopriya Das , Soo Lee , Hsin-Ru Chang
发明人： Mariah Baughn , Vicki Elliott , April Hafalia , Junming Yang , Narinder Chawla , Jayalaxmi Ramkumar , Ian Forsythe , Yan Lu , Y Tom Tang , Henry Yue , Brigitte Raumann , Preeti Lal , Yalda Azimzai , Dyung Lu , Ameena Gandhi , Michael Thornton , Danniel Nguyen , Chandra Arvizu , Brooke Emerling , Anita Swarnakar , Monique Yao , Li Ding , Ann He , Jennifer Griffin , Madhusudan Sanjanwala , Kimberly Gietzen , Ernestine Lee , Yuming Xu , Janice Au-Young , Debopriya Das , Soo Lee , Hsin-Ru Chang
IPC分类号： C07K14/705 , C07H21/04 , C12P21/06
CPC分类号： C12Q1/6886 , A61K31/706 , A61K38/00 , A61K48/00 , C07K14/4703 , C12Q1/683 , C12Q1/6858 , C12Q2600/154 , C12Q2600/158 , C12Q2521/331 , C12Q2531/113 , C12Q2523/125
摘要： The invention provides human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.
摘要翻译： 本发明提供了识别和编码TRICH的人转运体和离子通道（TRICH）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与TRICH异常表达相关的紊乱的方法。
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