公开(公告)号：US20210207178A1

公开(公告)日：2021-07-08

申请号：US16994240

申请日：2020-08-14

Applicant: Genomatica, Inc.

Inventor： Robin E. Osterhout ,  Anthony P. Burgard

IPC: C12P7/64 ,  C12P7/04 ,  C12P7/24 ,  C12N15/52 ,  C07C31/20 ,  C12N9/04 ,  C12N9/02 ,  C12N9/10 ,  C12N9/12 ,  C12N9/16 ,  C12N9/88 ,  C12N9/00

Abstract: The invention provides non-naturally occurring microbial organisms containing a fatty alcohol, fatty aldehyde or fatty acid pathway, wherein the microbial organisms selectively produce a fatty alcohol, fatty aldehyde or fatty acid of a specified length. Also provided are non-naturally occurring microbial organisms having a fatty alcohol, fatty aldehyde or fatty acid pathway, wherein the microbial organisms further include an acetyl-CoA pathway. In some aspects, the microbial organisms of the invention have select gene disruptions or enzyme attenuations that increase production of fatty alcohols, fatty aldehydes or fatty acids. The invention additionally provides methods of using the above microbial organisms to produce a fatty alcohol, a fatty aldehyde or a fatty acid.

公开(公告)号：US10975010B2

公开(公告)日：2021-04-13

申请号：US16426963

申请日：2019-05-30

Applicant: Iowa Corn Promotion Board

Inventor： David James Schreck ,  Ray Chrisman ,  Brooke Albin ,  Donald Bunning ,  Mark Nunley

IPC: C07C29/145 ,  B01J21/12 ,  B01J23/889 ,  B01J35/10 ,  C07C29/141 ,  C07C29/132 ,  B01J21/02 ,  B01J23/46 ,  B01J23/89 ,  C07C31/10 ,  C07C31/125 ,  C07C31/20 ,  C07C29/00

Abstract: Continuous processes for making ethylene glycol form aldohexose-yielding carbohydrates are disclosed which enhance the selectivity to ethylene glycol.

公开(公告)号：US10941092B2

公开(公告)日：2021-03-09

申请号：US16621050

申请日：2018-06-06

Applicant: BASF SE

Inventor： Marek Pazicky ,  Martin Ernst ,  Nicolas Marion ,  Rocco Paciello ,  Johann-Peter Melder ,  Hermann Luyken

IPC: C07C29/141 ,  C07D317/26 ,  B01J31/18 ,  C07C31/20

Abstract: The present invention relates to a two-stage hydroformylation process for producing pound of the formula (I) and to a process for producing a compound of the formula (V) comprising the two-stage hydroformylation process for producing a compound of the formula (I) followed by hydrogenation of the compound of the formula (I).

公开(公告)号：US10940465B2

公开(公告)日：2021-03-09

申请号：US16742479

申请日：2020-01-14

Applicant: Changchun Meihe Science and Technology Development Co., LTD ,  The Coca-Cola Company

Inventor： Jing Liu ,  Hongbin Qi ,  Haiyu Ren ,  Indra Prakash ,  Yu Shi

IPC: B01J23/10 ,  B01J25/02 ,  C07C31/22 ,  C07C31/20 ,  B01J37/00 ,  B01J37/08 ,  C07C29/132

Abstract: Disclosed is an acid-resistant alloy catalyst comprising nickel, one or more rare earth elements, stannum and aluminum. The acid-resistant alloy catalyst is low-cost and stable, and does not need a carrier, and can be stably used in continuous industrial production, thus achieving a low production cost.

公开(公告)号：US10858301B2

公开(公告)日：2020-12-08

申请号：US16616626

申请日：2018-05-25

Applicant: The Scripps Research Institute ,  Hyconix, Inc.

Inventor： Roy A. Periana ,  Brian G. Hashiguchi ,  Michael M. Konnick

IPC: C07C29/50 ,  C07C29/132 ,  C07C5/50 ,  C07C31/20

Abstract: Provided is a process for oxidizing an alkene. The process comprises contacting an alkene, and either an oxidizing electrophile comprising a main group element in oxidized form or an oxidant and a reduced form of the oxidizing electrophile, in a liquid medium comprising an oxygen acid and optionally one or more additives selected from a non-oxidizable liquid, a salt additive, a Lewis acid, and water, to provide an oxygenate and a reduced form of the oxidizing electrophile. The process optionally further comprises separating the oxygenate and the reduced form of the oxidizing electrophile. The oxygenate can be further hydrolyzed to form an alcohol, diol, or polyol.

公开(公告)号：US10759772B2

公开(公告)日：2020-09-01

申请号：US16097777

申请日：2017-04-28

Applicant: AUROBINDO PHARMA LIMITED ,  Senthilkumar Natrajan ,  Kishore Karumanchi ,  Vittal Tangirala ,  Sivakumaran Meenakshisunderam

Inventor： Senthilkumar Natrajan ,  Kishore Karumanchi ,  Vittal Tangirala ,  Sivakumaran Meenakshisunderam

IPC: C07D309/10 ,  C07D207/12 ,  C07C31/10 ,  C07D207/16 ,  C07C31/20

Abstract: The present invention relates to a process For the preparation of Dapagliflozin DL-Proline co-crystal and its use in the preparation/purification of Dapagliflozin. The invention also provides a process for the preparation of Dapagliflozin (R,S)-1.2-propanediol monohydrate.

公开(公告)号：US10752568B1

公开(公告)日：2020-08-25

申请号：US16443213

申请日：2019-06-17

Applicant: Zhangjiagang Glory Chemical Industry Co., Ltd.

Inventor： Changlin Chen ,  Xiaodong Zhu ,  Bing Han ,  Chengchao Xiao

IPC: C07C29/60 ,  B01J23/652 ,  C07C31/20 ,  B01J23/38

Abstract: The present disclosure provides a method for preparing 1,3-propanediol by hydrolysis hydrogenolysis of glycerol and its corresponding reaction system, wherein, this method is to produce 1,3-propanediol through contact and reaction between hydrogen and glycerol under the catalysis of a noble metal/solid acid catalyst; wherein an auxiliary agent is contained in the liquid phase of the reaction system, and the content of the auxiliary agent in the liquid phase is 10 ppm or more.

公开(公告)号：US10752567B2

公开(公告)日：2020-08-25

申请号：US16336140

申请日：2017-09-28

Applicant: SHELL OIL COMPANY

Inventor： Duraisamy Muthusamy ,  Viet Quoc Nguyen

IPC: C07C29/00 ,  B01J25/00 ,  B01J31/00 ,  C07C29/132 ,  B01J25/02 ,  B01J31/04 ,  C07C31/20

Abstract: Implementations of the disclosed subject matter provide methods for producing ethylene glycol from a carbohydrate feed which may include conditioning a heterogeneous hydrogenation catalyst by treatment with a protic acid resulting in an acid-conditioned heterogeneous hydrogenation catalyst. Next, in a reactor under hydrogenation conditions, the carbohydrate feed may be contacted with a bi-functional catalyst system comprising the acid-conditioned heterogeneous hydrogenation catalyst, and a soluble retro-Aldol catalyst. An intermediate product stream may be obtained from the reactor including ethylene glycol.

公开(公告)号：US10745345B2

公开(公告)日：2020-08-18

申请号：US15903779

申请日：2018-02-23

Applicant: ECOLAB USA INC.

Inventor： Anahita Khanlari ,  Andrew R. Neilson

IPC: C07C233/20 ,  C07C231/02 ,  C07C15/24 ,  C10G75/04 ,  C07D211/76 ,  C07D211/94 ,  C09K15/18 ,  C10G9/16 ,  C07C31/20

Abstract: Disclosed are compositions and methods for preventing or reducing polymer formation and polymer deposition in equipment used in petrochemical processes. An antifoulant composition includes a combination of one or more antioxidants; one or more antipolymerants; one or more dispersants; and one or more solvents. A method of preventing or reducing fouling of process equipment used in an industrial process is also described. The method includes introducing into the process equipment an antifoulant composition, the antifoulant composition comprising a combination of one or more antioxidants; one or more antipolymerants; one or more dispersants; and one or more solvents.

公开(公告)号：US10604496B2

公开(公告)日：2020-03-31

申请号：US15554922

申请日：2016-03-02

Applicant: SABIC Global Technologies B.V.

Inventor： Talal Al-Shammari ,  Khalid Karim ,  Zeeshan Nawaz ,  Ali Al-Hammad ,  Shehzada Khurram ,  Mubarik Ali Bashir ,  Labeeb Chaudhary Ahmed ,  Abdullah Turki Al-Jaloud ,  Saud Al-Khudeer ,  Thabet Al-Qahtani

IPC: C07D301/03 ,  C07D301/32 ,  C07C213/04 ,  C07C29/10 ,  C07C1/04 ,  C07C5/32 ,  C07C9/06 ,  C07C11/04 ,  C07C31/20 ,  C07C215/08 ,  C10G2/00

Abstract: Disclosed herein is a method comprising the steps of: a) producing a hydrocarbon stream from syngas via a Fischer-Tropsch reaction, wherein the hydrocarbon stream comprises a first C2 hydrocarbon stream comprising ethane and a first ethylene product; b) separating at least a portion of the first C2 hydrocarbon stream from the hydrocarbon stream; c) separating at least a portion of the first ethylene product from the first C2 hydrocarbon stream, thereby producing a second C2 hydrocarbon stream; d) converting at least a portion of the ethane in the second C2 hydrocarbon stream to a second ethylene product; and e) producing ethylene oxide from at least a portion of the second ethylene product.