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公开(公告)号:US20160113967A1
公开(公告)日:2016-04-28
申请号:US14860416
申请日:2015-09-21
发明人: Marc H. Hedrick , John K. Fraser
IPC分类号: A61K35/28 , C12N5/0775 , A61K9/00
CPC分类号: A61K35/28 , A61K9/0024 , A61K35/35 , C12N5/0653 , C12N5/0667 , C12N2509/00 , C12N2509/10
摘要: The invention provides methods for manipulating regenerative cells from adipose tissue. Specifically, it provides methods for enrichment of desired cells and enhancement of their therapeutic effects.
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公开(公告)号:US09198937B2
公开(公告)日:2015-12-01
申请号:US13725814
申请日:2012-12-21
发明人: John K. Fraser , Marc H. Hedrick
CPC分类号: A61K35/28 , A61B10/0283 , A61K9/0019 , A61K35/35 , A61M1/0039 , A61M2202/08 , C12M47/04 , C12N5/0667 , C12N5/069 , C12N2506/1384 , G06F19/00
摘要: Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.
摘要翻译: 存在于加工的lipoaspirate组织中的细胞用于治疗患者。 治疗患者的方法包括加工脂肪组织以将从脂肪组织获得的浓缩量的干细胞输送给患者。 所述方法可以在封闭系统中实施,使得干细胞在施用于患者之前不暴露于外部环境。 施用于患者的组合物包括脂肪组织和干细胞的混合物,使得组合物具有比从患者中除去脂肪组织时更高浓度的干细胞。
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公开(公告)号:US20140227234A1
公开(公告)日:2014-08-14
申请号:US14180553
申请日:2014-02-14
发明人: John K. Fraser , Marc H. Hedrick , Eric Daniels
CPC分类号: A61K35/28 , A61K9/0014 , A61K35/12 , A61K35/35 , A61K35/36 , A61K35/44 , A61K38/1866 , A61K45/06 , A61L15/40 , A61L15/44 , A61L27/3604 , A61L27/3834 , A61L27/54 , A61L27/56 , A61L2300/412 , A61L2300/64 , C12N5/0667 , C12N5/069 , C12N2506/1384 , A61K2300/00
摘要: Cells present in adipose tissue are used to promote wound healing in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the regenerative cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.
摘要翻译: 存在于脂肪组织中的细胞用于促进患者的伤口愈合。 治疗患者的方法包括加工脂肪组织以将从脂肪组织获得的浓缩量的再生细胞输送给患者。 所述方法可以在封闭系统中实施,使得再生细胞在施用于患者之前不暴露于外部环境。 因此,在优选的方法中,存在于脂肪组织中的细胞与促进,产生或支持治疗益处所必需的这种添加剂一起直接放置在受体中。
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