公开(公告)号：US20130057671A1

公开(公告)日：2013-03-07

申请号：US13558780

申请日：2012-07-26

Applicant: Daniel Levin ,  Lena Westervall ,  Susanna Leandersson ,  Peter Kronberg

Inventor： Daniel Levin ,  Lena Westervall ,  Susanna Leandersson ,  Peter Kronberg

IPC: H04N7/18

CPC classification number: G08B21/06 ,  A61B5/18 ,  A61B5/7221 ,  B60W40/08 ,  B60W2040/0827 ,  G06F19/00

Abstract: The present invention generally relates to a method for improving the reliability of a portion of physiological data from an image sensor monitoring an operator positioned in an operator compartment of a vehicle. An embodiment of the method includes receiving, from the image sensor, physiological data including information relating to at least one of eye, face, head, arms and body motion of the operator, identifying an indication of at least an eyelid closure, eye movement or head movement of the operator based on the physiological data; comparing at least one of the physiological data and a lighting condition within the operator compartment with a set of rules for a current operator status; and classifying the type of eyelid closure, eye movement and/or head movement by correlating the identified eyelid closure, eye movement and/or head movement and a result of the comparison.

Abstract translation: 本发明一般涉及一种用于提高来自监视位于车辆操作室中的操作员的图像传感器的一部分生理数据的可靠性的方法。 该方法的实施例包括从图像传感器接收生理数据，其包括与操作者的眼睛，脸部，头部，手臂和身体运动中的至少一个有关的信息，识别至少一个眼睑闭合，眼睛运动或 基于生理数据的操作员的头部运动; 将所述操作员室内的生理数据和照明条件中的至少一个与用于当前操作者状态的一组规则进行比较; 并通过将所识别的眼睑关闭，眼睛运动和/或头部移动与比较的结果相关联来分类眼睑闭合的类型，眼睛运动和/或头部运动。

公开(公告)号：US07960371B2

公开(公告)日：2011-06-14

申请号：US11867559

申请日：2007-10-04

Applicant: George S. Drummond ,  Robert Caroselli ,  Keith A. Cooke ,  Daniel Levin ,  David G. Roe ,  Christopher P. Boucher

Inventor： George S. Drummond ,  Robert Caroselli ,  Keith A. Cooke ,  Daniel Levin ,  David G. Roe ,  Christopher P. Boucher

IPC: C07B47/00 ,  C07D487/22 ,  A01N55/02

CPC classification number: C07F7/2284 ,  A61K9/0019 ,  A61K31/555 ,  C07D487/22 ,  C07F7/003

Abstract: Large scale (bulk) compositions comprising high-purity stannsoporfin are disclosed, as well as methods of synthesizing such compositions.

Abstract translation: 公开了包含高纯度固体锡的大规模（本体）组合物，以及合成这些组合物的方法。

公开(公告)号：US07777028B2

公开(公告)日：2010-08-17

申请号：US11957317

申请日：2007-12-14

Applicant: Robert A. Vukovich ,  Benjamin Levinson ,  George S. Drummond ,  Robert Caroselli ,  Kazimierz G. Antczak ,  Christopher P. Boucher ,  Richard Mortimer ,  Daniel Levin ,  Keith A. Cooke

Inventor： Robert A. Vukovich ,  Benjamin Levinson ,  George S. Drummond ,  Robert Caroselli ,  Kazimierz G. Antczak ,  Christopher P. Boucher ,  Richard Mortimer ,  Daniel Levin ,  Keith A. Cooke

IPC: C07B47/00

CPC classification number: C07D487/22 ,  C07F7/003 ,  C07F15/025

Abstract: A method of preparing metal mesoporphyrin halide compounds is described. The metal mesoporphyrin halide compound may be formed by forming a novel mesoporphyrin IX intermediate compound and then converting the mesoporphyrin IX intermediate to the metal mesoporphyrin halide through metal insertion. The novel intermediate compound may be formed by a catalytic hydrogenation of hemin in acid and subsequent recovery.

Abstract translation: 描述了制备金属中卟啉卤化物的方法。 金属中卟啉卤化物可以通过形成新的中卟啉IX中间体化合物形成，然后通过金属插入将中卟啉IX中间体转化成金属中卟啉卤化物。 新型中间体化合物可以通过氢氧化锂在酸中的催化氢化和随后的回收形成。

公开(公告)号：US07741473B2

公开(公告)日：2010-06-22

申请号：US11393374

申请日：2006-03-30

Applicant: Paul S. Watson ,  James G. Douglass, III ,  Bob Suchozak ,  Subramanian Pandiaraju ,  Craig E. Dixon ,  Daniel Levin

Inventor： Paul S. Watson ,  James G. Douglass, III ,  Bob Suchozak ,  Subramanian Pandiaraju ,  Craig E. Dixon ,  Daniel Levin

IPC: C07H19/067 ,  C07H19/167

CPC classification number: C07F9/6561 ,  C07F9/65616 ,  C07H19/06 ,  C07H19/10 ,  C07H19/16 ,  C07H19/20

Abstract: The present invention is directed to a processes for the synthesis of trans isomer of 4,6-disubstituted-tetrahydro-furo, thieno, pyrrolo and cyclopenta-[3,4][1,3]dioxoles (Formula I). The process comprises the steps of: (a) obtaining a compound of Formula II, which is a mixture of cis and trans-diastereomers, and (b) chemically decomposing the compound of Formula II in a solution comprising a solvent and an acid that is a hydrogen donor or an electron pair acceptor, whereby the cis diastereomer is decomposed and the compound of Formula I is obtained. The compounds prepared by the present invention are useful in treating diseases or conditions associated with platelet aggregation and/or platelet activation.

Abstract translation: 本发明涉及合成4,6-二取代 - 四氢 - 呋喃，噻吩并，吡咯并环戊烷并[3,4] [1,3]二氧杂环戊烯（式I）的反式异构体的方法。 该方法包括以下步骤：（a）获得式II化合物，其是顺式和反式 - 非对映异构体的混合物，和（b）在包含溶剂和酸的溶液中化学分解式II化合物， 氢供体或电子对受体，由此使顺式非对映异构体分解并得到式I化合物。 通过本发明制备的化合物可用于治疗与血小板聚集和/或血小板活化相关的疾病或病症。

公开(公告)号：US20080061958A1

公开(公告)日：2008-03-13

申请号：US11851678

申请日：2007-09-07

Applicant: Wolfgang Birk ,  Mattias Erik Brannstrom ,  Daniel Levin ,  Andreas Eidehall

Inventor： Wolfgang Birk ,  Mattias Erik Brannstrom ,  Daniel Levin ,  Andreas Eidehall

IPC: G08B23/00

CPC classification number: B60Q9/00 ,  B60T2201/022 ,  B60T2210/32 ,  B60W10/18 ,  B60W10/20 ,  B60W30/08 ,  B60W30/16 ,  B60W30/18172 ,  B60W40/04 ,  B60W40/08 ,  B60W50/14 ,  B60W2550/20 ,  B60W2550/306 ,  B60W2710/18 ,  B60W2710/20 ,  G08B21/06

Abstract: An active safety system for a vehicle includes an external object sensor system arranged on a host vehicle. The sensor system designed to sense objects external to the host vehicle and generate input data relating to the objects, wherein the input data includes an object position ((R, ψrel)(t)). Additionally, a threat indicator is included to assign a threat level (Tk(t)) to each external object (k) detected by the sensor system.

Abstract translation: 用于车辆的主动安全系统包括布置在主车辆上的外部物体传感器系统。 传感器系统被设计成感测主车辆外部的物体并产生与物体相关的输入数据，其中输入数据包括物体位置（（R，psi））。 此外，包括威胁指示符以将威胁等级（T k）（t））分配给由传感器系统检测到的每个外部对象（k）。

公开(公告)号：US20050182269A1

公开(公告)日：2005-08-18

申请号：US10518300

申请日：2003-06-18

Applicant: Ian Ashworth ,  Martin Bowden ,  Bruce Dembofsky ,  Daniel Levin

Inventor： Ian Ashworth ,  Martin Bowden ,  Bruce Dembofsky ,  Daniel Levin

IPC: C07C253/30 ,  C07B61/00 ,  C07C233/65 ,  C07C253/00 ,  C07C253/20 ,  C07C253/22 ,  C07C255/47 ,  C07C255/52 ,  C07C255/57 ,  C07C259/10 ,  C07D311/00

CPC classification number: C07D311/00 ,  C07C233/65 ,  C07C253/00 ,  C07C253/20 ,  C07C253/30 ,  C07C255/52 ,  C07C259/10 ,  C07C2602/10 ,  C07C255/57

Abstract: The present invention is related to a process for the preparation of 3-cyano-1-naphthoic acid and some analogues thereof of formula (1), the intermediate 1-halo-3-cyano naphthalene and some analogues thereof used in this process and a process for the preparation of said intermediate.

Abstract translation: 本发明涉及制备式（1）的3-氰基-1-萘甲酸及其一些类似物的方法，该方法中使用的中间体1-卤代-3-氰基萘及其一些类似物，和 所述中间体的制备方法。

公开(公告)号：US06740112B2

公开(公告)日：2004-05-25

申请号：US10314199

申请日：2002-12-09

Applicant: Ofer Yodfat ,  Ygael Grad ,  Yuval Yassour ,  Moshe Rosenfeld ,  Daniel Levin

Inventor： Ofer Yodfat ,  Ygael Grad ,  Yuval Yassour ,  Moshe Rosenfeld ,  Daniel Levin

IPC: A61F206

CPC classification number: A61F2/90 ,  A61F2/01 ,  A61F2/04 ,  A61F2/856 ,  A61F2/954 ,  A61F2/958 ,  A61F2002/018 ,  A61F2002/065 ,  A61F2002/068 ,  A61F2230/0006 ,  A61F2230/0069 ,  A61F2250/0017 ,  A61F2250/0024

Abstract: An implantable device for positioning about a blood vessel bifurcation zone to control flow of embolic material around said bifurcation. The device comprises an anchoring element extending within said zone of bifurcation to anchor said device therein, and a deflecting element, associated with said anchoring element, said deflecting element comprising a mesh having a mesh size sufficient to allow passage of blood without hindrance while occluding passage of embolic material exceeding a predetermined size.

Abstract translation: 一种可植入装置，用于围绕血管分叉区定位以控制围绕所述分叉的栓塞物质的流动。 所述装置包括在所述分叉区域内延伸以锚定所述装置的锚定元件，以及与所述锚固元件相关联的偏转元件，所述偏转元件包括网孔，所述网眼尺寸足以允许血液通过，同时阻塞通道 的栓塞材料超过预定尺寸。

公开(公告)号：US5502254A

公开(公告)日：1996-03-26

申请号：US404468

申请日：1995-03-15

Applicant: Daniel Levin

Inventor： Daniel Levin

IPC: B01J31/12 ,  B01J31/22 ,  C07B61/00 ,  C07C45/68 ,  C07C47/565 ,  C07C249/08 ,  C07C251/48

CPC classification number: C07C45/68 ,  C07C249/08 ,  C07C47/565

Abstract: A method for the preparation of a 2-hydroxyarylaldoxime which comprises reacting hydroxylamine with a 2-hydroxyarylaldehyde, said reaction being performed in the presence of a compound of a metal of Group II, Group III, Group IVA or Group VIA of the Periodic Table and/or under such conditions that the 2-hydroxyarylaldehyde is at least partially in the form of a salt and/or complex of a metal of Group II, Group III, Group IVA or Group VIA of the Periodic Table.

公开(公告)号：US5399761A

公开(公告)日：1995-03-21

申请号：US108424

申请日：1993-08-19

Applicant: Daniel Levin

Inventor： Daniel Levin

IPC: B01J31/12 ,  B01J31/22 ,  C07B61/00 ,  C07C45/68 ,  C07C47/565 ,  C07C249/08 ,  C07C251/48

CPC classification number: C07C45/68 ,  C07C249/08 ,  C07C47/565

Abstract: A method for the preparation of a 2-hydroxyarylaldoxime which comprises reacting hydroxylamine with a 2-hydroxyarylaldehyde, said reaction being performed in the presence of a compound of a metal of Group II, Group III, Group IVA or Group VIA of the Periodic Table and/or under such conditions that the 2-hydroxyarylaldehyde is at least partially in the form of a salt and/or complex of a metal of Group II, Group III, Group IVA or Group VIA of the Periodic Table.

Abstract translation: 一种2-羟基芳基醛肟的制备方法，其包括使羟胺与2-羟基芳基醛反应，所述反应是在元素周期表第II族，第III族，第IVA族或第VIA族的金属化合物存在下进行的，以及 /或在2-羟基芳基醛至少部分为元素周期表第II族，第III族，第IVA族或第VIA族金属的盐和/或络合物形式的条件下。

公开(公告)号：US5248816A

公开(公告)日：1993-09-28

申请号：US958058

申请日：1992-10-08

Applicant: Ralph Shuttleworth ,  Jan M. Fielden ,  Daniel Levin

Inventor： Ralph Shuttleworth ,  Jan M. Fielden ,  Daniel Levin

IPC: C07C51/347 ,  C07C45/29 ,  C07C45/30 ,  C07C45/38 ,  C07C47/565 ,  C07C51/367 ,  C07C59/52

CPC classification number: C07C45/38 ,  C07C45/29 ,  C07C45/294 ,  C07C45/30 ,  C07C51/367

Abstract: A method for the preparation of a 2-hydroxymandelic acid of the formula ##STR1## wherein R represents an alkyl radical containing from 7 to 12 carbon atoms which comprises reacting glyoxylic acid with a phenol of the formula: ##STR2## under acid conditions. Oxidation of the 2-hydroxymandelic acid to the corresponding 2-hydroxybenzaldehyde is also described.