公开(公告)号：US20250073446A1

公开(公告)日：2025-03-06

申请号：US18933749

申请日：2024-10-31

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/216 ,  A61M60/17 ,  A61M60/414 ,  A61M60/825 ,  A61M60/90

Abstract: Apparatus and methods are described including a solid axial shaft having a shaft diameter that is less than 0.8 mm, an impeller configured for insertion into a left ventricle of a heart of a subject and coupled to the axial shaft, and a hollow drive cable coupled, at a distal end of the drive cable, to the axial shaft, and configured to rotate so as to rotate the axial shaft, thereby causing the impeller to pump blood of the subject from the left ventricle. Other applications are also described.

公开(公告)号：US20250065104A1

公开(公告)日：2025-02-27

申请号：US18933729

申请日：2024-10-31

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/808 ,  A61M60/13 ,  A61M60/237

Abstract: Apparatus and methods are described including a blood pump that includes an axial shaft configured for insertion into, and rotation within, a subject's body. The blood pump also includes an impeller, which includes a proximal bushing disposed over the axial shaft, a distal bushing disposed over the axial shaft distally from the proximal bushing, and one or more blades. Each of the blades includes a single inner helical elongate element, a single outer helical elongate element, and a film of material extending between the inner helical elongate element and the outer helical elongate element. The blades are proximally coupled to the proximal bushing and distally coupled to the distal bushing such that, as the axial shaft rotates, the blades rotate, thereby pumping blood of the subject. Other applications are also described.

公开(公告)号：US20250065100A1

公开(公告)日：2025-02-27

申请号：US18947762

申请日：2024-11-14

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Jacob Leisner Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M60/148 ,  A61M60/122 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/205 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/804 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/38 ,  F04D29/52 ,  F04D29/54

Abstract: Apparatus and methods are described including a left-ventricular assist device that includes a frame that includes proximal and distal frame portions that include struts that define cells, and a central frame portion that includes helical struts. An impeller is disposed inside the frame, the impeller being configured to rotate such as to pump blood from a left ventricle of a subject to an aorta of the subject. Other applications are also described.

公开(公告)号：US12128228B2

公开(公告)日：2024-10-29

申请号：US17608312

申请日：2020-05-20

Applicant: MAGENTA MEDICAL LTD

Inventor： Ori Friedland ,  Yuval Zipory ,  Yuri Sudin ,  Ayelet Haimy ,  Ehud Schwammenthal ,  Yosi Tuval ,  Tak Gee Cheung

IPC: A61M60/13 ,  A61B17/12 ,  A61M60/178 ,  A61M60/216 ,  A61M60/531 ,  A61M60/546 ,  A61M60/833 ,  A61M60/857 ,  A61M60/867

CPC classification number: A61M60/531 ,  A61B17/12181 ,  A61M60/13 ,  A61M60/178 ,  A61M60/216 ,  A61M60/546 ,  A61M60/833 ,  A61M60/867

Abstract: Apparatus and methods are described for use with a venous system of a subject that includes one or more tributary vessels that flow into a vein at junctions. A blood-pump-catheter (70) includes a material (36) configured to be placed at a downstream location that is downstream of the junctions and to at least partially occlude blood flow through the vein. The material defines a blood-outlet opening (31). A blood pump (24) pumps blood from a region of the vein that is adjacent to the junctions, and through the blood-outlet opening (31). A blood-flow pathway (60) directs upstream venous blood flow from an upstream location that is upstream of the junctions, to downstream of the material (36), without the upstream venous blood flow being pumped by the pump (24). Other applications are also described.

公开(公告)号：US12128227B2

公开(公告)日：2024-10-29

申请号：US17528807

申请日：2021-11-17

Applicant: MAGENTA MEDICAL LTD.

Inventor： Yosi Tuval ,  Yinnon Elisha ,  David Israeli ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yuval Zipory ,  Avi Rozenfeld ,  Aurelie Benaddi ,  Gilad Moiseyev ,  Yuri Sudin

IPC: A61M60/237 ,  A61B5/021 ,  A61B5/0215 ,  A61M60/13 ,  A61M60/135 ,  A61M60/174 ,  A61M60/178 ,  A61M60/216 ,  A61M60/226 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/523 ,  A61M60/531 ,  A61M60/538 ,  A61M60/546 ,  A61M60/808 ,  A61M60/816 ,  A61M60/818 ,  A61M60/825 ,  A61M60/857 ,  A61M60/865 ,  A61M60/804 ,  A61M60/829

CPC classification number: A61M60/237 ,  A61B5/02141 ,  A61B5/0215 ,  A61M60/13 ,  A61M60/135 ,  A61M60/174 ,  A61M60/178 ,  A61M60/216 ,  A61M60/226 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/523 ,  A61M60/531 ,  A61M60/538 ,  A61M60/546 ,  A61M60/808 ,  A61M60/816 ,  A61M60/818 ,  A61M60/825 ,  A61M60/857 ,  A61M60/865 ,  A61B2562/0223 ,  A61M60/804 ,  A61M60/829 ,  A61M2205/3327 ,  A61M2207/00

Abstract: Apparatus and methods are described including manufacturing an impeller by forming a structure having first and second bushings at proximal and distal ends of the structure, the first and second bushings being connected to one another by at least one elongate element. The elongate element is caused to radially expand and form at least one helical elongate element, at least partially by axially compressing the structure. The helical elongate element is coated with a coupling agent configured to enhance bonding between the helical elongate element and an elastomeric layer. The coated helical elongate element is coated with the elastomeric layer. Subsequently, an elastomeric film is coupled to the helical elongate element, such that the helical elongate element with the elastomeric film coupled thereto defines a blade of the impeller. Other applications are also described.

公开(公告)号：US12090314B2

公开(公告)日：2024-09-17

申请号：US17574701

申请日：2022-01-13

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Daniel Glozman ,  Gad Lubinsky

IPC: A61M1/00 ,  A61M60/139 ,  A61M60/148 ,  A61M60/17 ,  A61M60/237 ,  A61M60/414 ,  A61M60/806 ,  A61M60/825

CPC classification number: A61M60/414 ,  A61M60/139 ,  A61M60/148 ,  A61M60/17 ,  A61M60/237 ,  A61M60/806 ,  A61M60/825 ,  A61M2205/3334 ,  A61M2230/30

Abstract: Apparatus and methods are described including a tube configured to traverse an aortic valve of a subject. A frame is disposed within at least a portion of the tube. An impeller rotates such as to pump blood from the subject's left ventricle to the subject's aorta. The impeller is disposed inside the tube such that, when the impeller and the tube are deployed inside the subject, and prior to rotation of the impeller, a gap between an outer edge of the impeller and an inner surface of the tube is less than 1 mm. A rigid stabilizing element stabilizes the impeller with respect to the tube, such that during rotation of the impeller, a gap between the outer edge of the impeller and the inner surface of the tube is maintained. Other applications are also described.

公开(公告)号：US20240277997A1

公开(公告)日：2024-08-22

申请号：US18652959

申请日：2024-05-02

Applicant: Magenta Medical Ltd

Inventor： Yosi Tuval ,  Gad Lubinsky ,  Victor Troshin ,  Hagit Zemer Harel ,  Ori Friedland ,  Daniel Rosenblum ,  Avi Rozenfeld

IPC: A61M60/808 ,  A61M60/13 ,  A61M60/174 ,  A61M60/237 ,  A61M60/414 ,  A61M60/81 ,  A61M60/825

CPC classification number: A61M60/808 ,  A61M60/13 ,  A61M60/174 ,  A61M60/237 ,  A61M60/414 ,  A61M60/81 ,  A61M60/825

Abstract: Apparatus and methods are described including a pump-outlet tube configured to traverse an aortic valve of a subject, such that the proximal end of the pump-outlet tube is disposed within the subject's aorta and the distal end of the pump-outlet tube is disposed within the subject's left ventricle. An impeller is configured to be disposed within the left ventricle within the pump-outlet tube, and to pump blood through the pump-outlet tube. A frame, disposed around the impeller, includes a cylindrical portion and a proximal conical portion. A proximal end of an optical fiber is disposed outside the subject's body and the distal end of the optical fiber is coupled to the proximal conical portion of the frame such that the distal end of the optical fiber extends to outside the pump-outlet tube in direct fluid communication with left-ventricular bloodstream of the subject. Other applications are also described.

公开(公告)号：US20240269457A1

公开(公告)日：2024-08-15

申请号：US18640222

申请日：2024-04-19

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/17 ,  A61M60/13 ,  A61M60/414 ,  A61M60/554 ,  A61M60/585 ,  A61M60/808 ,  A61M60/81

CPC classification number: A61M60/17 ,  A61M60/13 ,  A61M60/414 ,  A61M60/554 ,  A61M60/585 ,  A61M60/808 ,  A61M60/81 ,  A61M2205/04 ,  A61M2205/103 ,  A61M2205/3303 ,  A61M2205/3331 ,  A61M2205/502 ,  A61M2210/125 ,  A61M2230/30

Abstract: Apparatus and methods are described including a device configured for insertion into a left ventricle of a heart of a subject. A delivery tube is coupled to the device and configured to traverse an aortic arch of the subject while the device is within the left ventricle. An elongation-resistant fiber runs axially along the delivery tube so as to bias an orientation of the delivery tube while the delivery tube traverses the aortic arch such that the elongation-resistant fiber is disposed inside a curve of the aortic arch, thereby biasing an orientation of the device. Other applications are also described.

公开(公告)号：US12059235B2

公开(公告)日：2024-08-13

申请号：US17069570

申请日：2020-10-13

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61B5/0215 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/554 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/00 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/18 ,  F04D29/24

CPC classification number: A61B5/0215 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/554 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/0066 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/181 ,  F04D29/247 ,  A61M2205/0266 ,  A61M2205/3317 ,  A61M2205/3327 ,  A61M2205/3334 ,  A61M2205/3344 ,  A61M2205/3365 ,  A61M2205/50 ,  A61M2230/04 ,  A61M2230/30

Abstract: Apparatus and methods are described including a blood pump catheter that includes an axial shaft, and an impeller disposed on the axial shaft. A motor drives the impeller to pump blood, by rotating the impeller. A drive cable extends from the motor to the axial shaft, the drive cable being configured to impart rotational motion from the motor to the impeller by rotating. A distal tip portion is disposed at a distal end of the blood pump catheter. The drive cable, the axial shaft, and the distal tip portion define a continuous lumen therethrough from outside the subject's body to the distal end of the blood pump catheter. The continuous lumen facilitates insertion of the blood pump catheter into the subject's body over a guidewire, and, subsequently, provides a channel through which the purging fluid flows. Other applications are also described.

公开(公告)号：US20240261563A1

公开(公告)日：2024-08-08

申请号：US18637655

申请日：2024-04-17

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/414 ,  A61L29/02 ,  A61M39/10 ,  A61M60/13 ,  A61M60/174 ,  A61M60/242 ,  A61M60/806 ,  A61M60/81 ,  A61M60/825

CPC classification number: A61M60/414 ,  A61L29/02 ,  A61M39/10 ,  A61M60/13 ,  A61M60/174 ,  A61M60/242 ,  A61M60/806 ,  A61M60/81 ,  A61M60/825 ,  A61M2039/1077

Abstract: Apparatus and methods are described including inserting a drive-cable end of a drive cable, which includes a plurality of coiled wires, and a hollow-shaft end of a hollow shaft, which hollow-shaft end is shaped to define multiple shaft pores, into opposing ends of a coupling tube having a wall shaped to define multiple tabs. The drive cable is coupled to the shaft by pushing at least some of the tabs into the shaft pores, respectively. Other applications are also described.