公开(公告)号：US07672172B2

公开(公告)日：2010-03-02

申请号：US12333674

申请日：2008-12-12

申请人： Minoru Fukuda ,  Hiroaki Nakanishi ,  Kunio Matsudaira ,  Masahiro Matsuo ,  Hirohisa Abe

发明人： Minoru Fukuda ,  Hiroaki Nakanishi ,  Kunio Matsudaira ,  Masahiro Matsuo ,  Hirohisa Abe

IPC分类号： G11C16/04

CPC分类号： G11C16/16

摘要： The present invention is related to a composite flash memory device comprises a plural sector flash memory array which is divided to plural sector that is a minimum erasing unit of the flash memory device, a flash memory array storing control commands which control a total system of the composite flash memory device and/or the only composite flash memory device in and sharing I/O line of the plural sector flash memory array, the read operation of the flash memory array is enable when the plural sector flash memory array is gained access.

摘要翻译： 本发明涉及一种复合闪速存储装置，它包括被分成多个扇区的多扇区快闪存储器阵列，该多个扇区闪速存储器阵列是闪速存储器件的最小擦除单元，存储控制命令的闪存阵列， 复合闪速存储器件和/或唯一的复合闪速存储器件，并且共享多扇区快闪存储器阵列的I / O线，当获得多个扇区闪速存储器阵列时，闪存阵列的读取操作成立。

公开(公告)号：US20080122547A1

公开(公告)日：2008-05-29

申请号：US12009406

申请日：2008-01-18

申请人： Manabu Ito ,  Minoru Fukuda ,  Tetuo Kudo ,  Takeshi Uchida

发明人： Manabu Ito ,  Minoru Fukuda ,  Tetuo Kudo ,  Takeshi Uchida

IPC分类号： H03L1/04 ,  H03B5/04 ,  H03B5/32

CPC分类号： H03B5/36 ,  H03B5/04 ,  H03L1/04 ,  H05K1/0212 ,  H05K1/0243 ,  H05K3/306 ,  H05K2201/062 ,  H05K2201/09063 ,  H05K2201/10022 ,  H05K2201/10068 ,  H05K2201/10151 ,  H05K2201/10522 ,  H05K2201/2036

摘要： A lead wire led-out type crystal oscillator of constant temperature type for high stability is disclosed, which includes a heat supply body that supplies heat to a crystal resonator from which a plurality of lead wires are led out, to maintain the temperature constant. The heat supply body includes a heat conducting plate which has through-holes for the lead wires and is mounted on the circuit board, and which faces, and is directly thermally joined to, the crystal resonator and a chip resistor for heating which is mounted on the circuit board adjacent to the heat conducting plate, and is thermally joined to the heat conducting plate.

摘要翻译： 公开了一种用于高稳定性的恒温型引线引出型晶体振荡器，其包括向多个引线从其引出的晶体谐振器供热，以保持温度恒定的供热体。 供热体包括：导热板，其具有用于引线的通孔并且安装在电路板上，并且面向并直接热连接到晶体谐振器和用于加热的片状电阻器 电路板与导热板相邻，并且热连接到导热板。

公开(公告)号：US07372999B2

公开(公告)日：2008-05-13

申请号：US10658870

申请日：2003-09-09

申请人： Shogo Oneda ,  Keiichi Suzuki ,  Yukio Kadowaki ,  Yutaka Sano ,  Tooru Suino ,  Takanori Yano ,  Minoru Fukuda

发明人： Shogo Oneda ,  Keiichi Suzuki ,  Yukio Kadowaki ,  Yutaka Sano ,  Tooru Suino ,  Takanori Yano ,  Minoru Fukuda

IPC分类号： G06K9/36 ,  G06K9/00 ,  G06K9/46

CPC分类号： H04N19/184 ,  H04N19/132 ,  H04N19/156 ,  H04N19/17 ,  H04N19/18 ,  H04N19/63

摘要： An image decoder comprises a code decompression/decoding unit that decodes code data produced through compression and encoding of image data, a power supply state detection unit that detects a current state of a power supply of the image decoder, and a controller that controls the code decompression/decoding unit based on the current state of the power supply so as to reduce power consumption in performing decompression and decoding of the code data.

摘要翻译： 图像解码器包括解码通过图像数据的压缩和编码产生的代码数据的代码解压缩/解码单元，检测图像解码器的电源的当前状态的电源状态检测单元和控制代码的控制器 基于电源的当前状态的解压缩解码单元，以减少对代码数据进行解压缩和解码的功耗。

公开(公告)号：US20070275420A1

公开(公告)日：2007-11-29

申请号：US10549811

申请日：2004-03-19

申请人： Chikara Ohyama ,  Minoru Fukuda

发明人： Chikara Ohyama ,  Minoru Fukuda

IPC分类号： G01N33/574 ,  C07K16/40

CPC分类号： G01N33/57434 ,  C12Q1/48 ,  G01N33/574 ,  G01N33/57407

摘要： It is to provide a method and a kit for detecting the prognosis of cancer at high accuracy in a simple and rapid manner at low cost. The method is specifically a method for detecting the prognosis of cancer, at least including a step of detecting core-2 β 1,6-acetylglucosaminyltransferase in a sample collected from a biological organism to examine the relationship between the results of the detection and the prognosis of cancer in the biological organism, wherein core-2 β1,6-acetylglucosaminyltransferase is preferably core-2 β1,6-acetylglucosaminyltransferase-I; the biological organism is preferably human body; and the sample is preferably a living tissue.

摘要翻译： 它以低成本提供以高精度以简单快速的方式检测癌症的预后的方法和试剂盒。 该方法特别是用于检测癌症预后的方法，至少包括在从生物有机体收集的样品中检测核-2β1,6-乙酰葡糖胺基转移酶的步骤，以检查检测结果与预后之间的关系 其中核-2β1,6-乙酰葡糖胺基转移酶优选为核-2β1,6-乙酰葡糖胺基转移酶-I; 生物体优选为人体; 样品优选为活组织。

公开(公告)号：US20070142319A1

公开(公告)日：2007-06-21

申请号：US10589835

申请日：2005-02-17

申请人： Jamey Marth ,  Minoru Fukuda

发明人： Jamey Marth ,  Minoru Fukuda

IPC分类号： A61K31/715

CPC分类号： A61K31/00 ,  A61K31/715 ,  G01N33/6896 ,  G01N2333/91148 ,  G01N2500/04 ,  G01N2800/301

摘要： The invention provides methods and compositions for treating anxiety and fear disorders through inhibition of α-2,8-sialyltransferase activity.

摘要翻译： 本发明提供了通过抑制α-2,8-唾液酸转移酶活性来治疗焦虑和恐惧障碍的方法和组合物。

公开(公告)号：US07088032B2

公开(公告)日：2006-08-08

申请号：US11154289

申请日：2005-06-16

申请人： Takeo Oita ,  Minoru Fukuda

发明人： Takeo Oita ,  Minoru Fukuda

IPC分类号： H01L41/08

CPC分类号： H03B5/32 ,  H03H9/02102 ,  H03H9/0528 ,  H03H9/0542 ,  H03H9/0552 ,  H03H9/1014 ,  H03L1/04

摘要： A crystal oscillator of the present invention includes: a substrate provided in a package; a heating device arranged as surrounding an internal area of the substrate on at least one of the surfaces of the substrate; a crystal resonator or a crystal element and an oscillation circuit unit provided in an area enclosed by the heating device; a thermosensitive element which detects a temperature in an area enclosed by the heating device; and a control unit for controlling a heating value applied to the heating device based on a detection result of the thermosensitive element.

摘要翻译： 本发明的晶体振荡器包括：设置在封装中的衬底; 加热装置，其布置成在所述基板的至少一个表面上包围所述基板的内部区域; 设置在由加热装置封闭的区域中的晶体谐振器或晶体元件和振荡电路单元; 热敏元件，其检测由所述加热装置包围的区域中的温度; 以及控制单元，用于基于热敏元件的检测结果控制施加到加热装置的加热值。

公开(公告)号：US20060063489A1

公开(公告)日：2006-03-23

申请号：US11230756

申请日：2005-09-19

申请人： Kazuo Akaike ,  Makoto Okamoto ,  Tsutomu Yamakawa ,  Minoru Fukuda ,  Kozo Ono ,  Nobuo Tsukamoto

发明人： Kazuo Akaike ,  Makoto Okamoto ,  Tsutomu Yamakawa ,  Minoru Fukuda ,  Kozo Ono ,  Nobuo Tsukamoto

IPC分类号： H04B7/00 ,  H04M1/00

CPC分类号： H04B1/30

摘要： A high-frequency wireless communication device is provided that is capable of enlarging the range of communication by enhancing reception sensitivity while avoiding mutual interference. The device comprises an antenna filter and a direct detection type reception mechanism connected to the antenna filter. A crystal filter is used as the antenna filter. A crystal chip constituting the crystal filter and an IC chip into which the reception mechanism is integrated are housed in a single modular container to configure a high-frequency wireless module.

公开(公告)号：US06566497B1

公开(公告)日：2003-05-20

申请号：US09146084

申请日：1998-09-02

申请人： Minoru Fukuda ,  Akiko Kanamori ,  Yoshio Hirabayashi

发明人： Minoru Fukuda ,  Akiko Kanamori ,  Yoshio Hirabayashi

IPC分类号： C07K100

CPC分类号： G01N33/6842 ,  C07K14/47 ,  C12Q1/6876 ,  G01N33/68 ,  Y10S435/975

摘要： In accordance with the present invention, there are provided isolated mammalian Acetyl-Coenzyme A Transporter (AT) proteins, anti-AT antibodies, therapeutic compositions, and nucleic acids encoding such. Bioassays and therapeutic methods employing invention AT proteins are also provided.

摘要翻译： 根据本发明，提供了分离的哺乳动物乙酰辅酶A转运蛋白（AT）蛋白，抗AT抗体，治疗组合物和编码其的核酸。 还提供了使用发明AT蛋白的生物测定和治疗方法。

公开(公告)号：US06537553B1

公开(公告)日：2003-03-25

申请号：US08369754

申请日：1995-01-06

申请人： Minoru Fukuda ,  Ritsuko Sawada ,  Shigeru Tsuboi

发明人： Minoru Fukuda ,  Ritsuko Sawada ,  Shigeru Tsuboi

IPC分类号： C12P2100

CPC分类号： C07K14/705 ,  A61K38/00 ,  C07K14/47

摘要： The present invention provides antagonists to cell adhesion useful in controlling the negative effects of inflammation, and the metastasis of cancer cells. These antagonists are ligands to E-selectin containing the sialyl Lex structure, including sialyl Lex glycoproteins, sialyl Lex glycolipids, and sialyl Lex oligsaccharides, and other related sialyl Lex-containing molecules capable of inhibiting E-selectin mediated cell adhesion to endothelial cells. The present invention also provides antibodies against sialyl Lex determinants capable of interrupting E-selectin mediated cell adhesion, which are also considered antagonists according to the present invention. The present invention also provides methods of using the antagonists of the present invention to reduce inflammation, and methods to inhibit the process of metastasis by carcinogenic cells. The present invention also provides nucleic acid molecules encoding the glycoprotein antagonists of the present invention, in particular soluble chimeric leukosialin, and vectors capable of expressing these nucleic acid molecules, as well as cells capable of producing sialyl Lex positive recombinant glycoproteins. The present invention further provides a method of determining metastatic potential by comparing the efficiency of E-selectin-mediated adhesion of cell samples. In addition the present invention provides a method of producing a preferred antagonist of the present invention, sialyl Lex positive glycoproteins, in particular, sialy Lex positive chimeric leukosialin.

摘要翻译： 本发明提供了可用于控制炎症的负面作用和癌细胞转移的细胞粘附的拮抗剂。 这些拮抗剂是含有唾液酸Lex结构的E-选择素的配体，包括唾液酸Lex糖蛋白，唾液酸Lex糖脂和唾液酸Lex低聚糖，以及能够抑制E-选择蛋白介导的细胞粘附于内皮细胞的其它相关唾液酸含Lex分子。 本发明还提供能够中断E-选择蛋白介导的细胞粘附的唾液酸基决定簇的抗体，其也被认为是根据本发明的拮抗剂。 本发明还提供了使用本发明的拮抗剂来减少炎症的方法，以及抑制致癌细胞转移过程的方法。 本发明还提供编码本发明的糖蛋白拮抗剂，特别是可溶性嵌合白血球蛋白的核酸分子，以及能够表达这些核酸分子的载体，以及能产生唾液酸Lex阳性重组糖蛋白的细胞。 本发明还提供了通过比较E-选择蛋白介导的细胞样品粘附的效率来确定转移潜能的方法。 此外，本发明提供了制备本发明优选的拮抗剂，唾液酸Lex阳性糖蛋白，特别是唾液酸Lex阳性嵌合白血球蛋白的方法。

公开(公告)号：US06451969B1

公开(公告)日：2002-09-17

申请号：US09232484

申请日：1999-01-15

申请人： Michiko Fukuda ,  Minoru Fukuda

发明人： Michiko Fukuda ,  Minoru Fukuda

IPC分类号： C07K500

CPC分类号： C07K7/06 ,  A61K38/00

摘要： In accordance with the present invention, there are provided peptides that bind to a member of the mammalian selectin family and inhibit the binding of a carbohydrate to the selectin. Invention peptides are useful to inhibit of the adhesion of cells containing particular cell-surface carbohydrates to cells containing cell-surface selecting. Also provided are pharmaceutical compositions comprising invention peptides useful in methods for inhibiting a carbohydrate from binding to a selectin, and in methods of inhibiting tumor cell metastasis in a subject.

摘要翻译： 根据本发明，提供了结合哺乳动物选择蛋白家族成员并抑制碳水化合物与选择蛋白结合的肽。 本发明的肽可用于抑制含有特定细胞表面碳水化合物的细胞对含有细胞表面选择的细胞的粘附。 还提供了包含可用于抑制碳水化合物与选择素结合的方法的发明肽的药物组合物，以及抑制受试者中肿瘤细胞转移的方法。