公开(公告)号：US08097588B2

公开(公告)日：2012-01-17

申请号：US12026810

申请日：2008-02-06

申请人： Michiko Fukuda

发明人： Michiko Fukuda

IPC分类号： A61K38/00

CPC分类号： C07K5/1008 ,  A61K38/00 ,  C07K7/06

摘要： Disclosed herein are compositions and methods useful for promoting sperm motility, promoting embryonic stem cell formation, promoting trophoblast formation, or promoting neuronal growth. The compositions and methods are based on peptide sequences that bind trophinin, inhibit bystin-mediated arrest of epidermal growth factor (EGF) receptor, and promotes EGF receptor autophosphorylation.

摘要翻译： 本文公开了可用于促进精子活力，促进胚胎干细胞形成，促进滋养层形成或促进神经元生长的组合物和方法。 组合物和方法基于结合营养蛋白的肽序列，抑制通过介导的表皮生长因子（EGF）受体的阻滞，并促进EGF受体自磷酸化。

公开(公告)号：US07470658B2

公开(公告)日：2008-12-30

申请号：US10193979

申请日：2002-07-12

申请人： Michiko Fukuda ,  Minoru Fukuda

发明人： Michiko Fukuda ,  Minoru Fukuda

IPC分类号： A61K38/00 ,  A61K38/08 ,  C07K7/06 ,  C07K14/00

CPC分类号： C07K7/06 ,  A61K38/00

摘要： In accordance with the present invention, there are provided peptides that bind to a member of the mammalian selectin family and inhibit the binding of a carbohydrate to the selectin. Invention peptides are useful to inhibit of the adhesion of cells containing particular cell-surface carbohydrates to cells containing cell-surface selectins. Also provided are pharmaceutical compositions comprising invention peptides useful in methods for inhibiting a carbohydrate from binding to a selectin, and in methods of inhibiting tumor cell metastasis in a subject.

摘要翻译： 根据本发明，提供了结合哺乳动物选择蛋白家族成员并抑制碳水化合物与选择蛋白结合的肽。 本发明的肽可用于抑制含有特定细胞表面碳水化合物的细胞对含有细胞表面选择素的细胞的粘附。 还提供了包含可用于抑制碳水化合物与选择素结合的方法的发明肽的药物组合物，以及抑制受试者中肿瘤细胞转移的方法。

公开(公告)号：US07129969B2

公开(公告)日：2006-10-31

申请号：US10043784

申请日：2001-11-07

申请人： Michiko Fukuda

发明人： Michiko Fukuda

IPC分类号： H04N7/14

CPC分类号： H04M1/27455 ,  H04M1/576

摘要： When a telephone unit communicates with a communication party using a television telephone function, a receiving portion of the telephone unit receives compressed moving picture data from the communication party having a moving picture encoder through a communication network. While the received moving picture compressed data is successively decoded by a moving picture decoder and displayed on a displaying device or the like, when the user of the telephone unit performs an inputting operation equivalent to a shutter operation, one frame of decoded picture data at the timing is supplied to a still picture encoder and encoded as still picture compressed data. In addition, a communication party telephone number detecting portion detects the telephone number of the communication party and stores it to a telephone directory along with the compressed still picture data.

公开(公告)号：US06842507B2

公开(公告)日：2005-01-11

申请号：US10290455

申请日：2002-11-08

申请人： Michiko Fukuda

发明人： Michiko Fukuda

IPC分类号： H04N5/907 ,  H04M1/00 ,  H04M1/64 ,  H04M1/65 ,  H04M1/725 ,  H04M11/00 ,  H04M11/10 ,  H04N5/765 ,  H04N7/14 ,  H04Q7/38

CPC分类号： H04N7/147 ,  H04M1/642 ,  H04M1/6505 ,  H04M1/72522

摘要： A destination portable phone comprises a multimedia file retention memory 100 for storing and retaining voice data and image data specified as a video answerphone message in a multimedia file format that enables synchronous reproduction of the data, an answerphone mode starting unit for starting the memory to read out the message at the answerphone setting when a call is originated from a transmitting unit of an origination portable phone by opening a voice channel, and a transmitting unit for receiving and transmitting the message by opening the data channel.

摘要翻译： 目的地便携式电话包括：多媒体文件保持存储器100，用于存储和保留以能够同步再现数据的多媒体文件格式指定为视频应答电话消息的语音数据和图像数据;应答电话模式启动单元，用于启动存储器读取 当通过打开语音信道从起始便携式电话的发送单元发起呼叫时，在接听电话设置中输出消息;以及发送单元，用于通过打开数据信道来接收和发送消息。

公开(公告)号：US09006404B2

公开(公告)日：2015-04-14

申请号：US11616098

申请日：2006-12-26

申请人： Michiko Fukuda ,  Daisuke Aoki ,  Noriko Nozawa

发明人： Michiko Fukuda ,  Daisuke Aoki ,  Shiro Nozawa

IPC分类号： C07H21/04 ,  C07K7/08 ,  A61K38/08 ,  C07K7/06 ,  C07K14/00

CPC分类号： C07K7/08 ,  A61K31/7028 ,  A61K38/08 ,  A61K45/06 ,  A61K47/48246 ,  A61K47/64 ,  A61K49/0056 ,  C07K7/06 ,  C07K14/001 ,  G01N33/56966 ,  G01N2800/364 ,  A61K2300/00

摘要： Provided herein are compositions and methods for selectively targeting an endometriosis cell.

摘要翻译： 本文提供了选择性靶向子宫内膜异位症细胞的组合物和方法。

公开(公告)号：US20080200369A1

公开(公告)日：2008-08-21

申请号：US12026810

申请日：2008-02-06

申请人： Michiko Fukuda

发明人： Michiko Fukuda

IPC分类号： A61K38/00 ,  C07K16/00 ,  C07H21/04 ,  A61K31/70 ,  A01N1/02 ,  C12N15/00 ,  C12N5/00

CPC分类号： C07K5/1008 ,  A61K38/00 ,  C07K7/06

摘要： Disclosed herein are compositions and methods useful for promoting sperm motility, promoting embryonic stem cell formation, promoting trophoblast formation, or promoting neuronal growth. The compositions and methods are based on peptide sequences that bind trophinin, inhibit bystin-mediated arrest of epidermal growth factor (EGF) receptor, and promotes EGF receptor autophosphorylation.

摘要翻译： 本文公开了可用于促进精子活力，促进胚胎干细胞形成，促进滋养层形成或促进神经元生长的组合物和方法。 组合物和方法基于结合营养蛋白的肽序列，抑制通过介导的表皮生长因子（EGF）受体的阻滞，并促进EGF受体自磷酸化。

公开(公告)号：US20080008650A1

公开(公告)日：2008-01-10

申请号：US11616098

申请日：2006-12-26

申请人： Michiko Fukuda ,  Daisuke Aoki ,  Shiro Nozawa ,  Noriko Nozawa

发明人： Michiko Fukuda ,  Daisuke Aoki ,  Shiro Nozawa ,  Noriko Nozawa

IPC分类号： A61P5/00 ,  A61K38/02 ,  C07H21/00 ,  A61K49/00

CPC分类号： C07K7/08 ,  A61K31/7028 ,  A61K38/08 ,  A61K45/06 ,  A61K47/48246 ,  A61K47/64 ,  A61K49/0056 ,  C07K7/06 ,  C07K14/001 ,  G01N33/56966 ,  G01N2800/364 ,  A61K2300/00

摘要： Provided herein are compositions and methods for selectively targeting an endometriosis cell.

摘要翻译： 本文提供了选择性靶向子宫内膜异位症细胞的组合物和方法。

公开(公告)号：US20070105705A1

公开(公告)日：2007-05-10

申请号：US11493207

申请日：2006-07-25

申请人： Michiko Fukuda ,  Akiko Fukuda

发明人： Michiko Fukuda ,  Akiko Fukuda

IPC分类号： C04B38/00 ,  C04B33/36

CPC分类号： C04B35/16 ,  C04B33/1355 ,  C04B33/1357 ,  C04B35/6263 ,  C04B38/0665 ,  C04B2111/00129 ,  C04B2111/343 ,  C04B2235/3208 ,  C04B2235/6021 ,  C04B2235/96 ,  Y02P40/69 ,  C04B38/0054 ,  C04B38/0074

摘要： Porous ceramic having a homogenous pore structure in which pores having radii in a narrow range of 300 to 4000 nm occupy 90% or more of the total pore capacity. The porous ceramic is manufactured by a method including a first step of drying an initial composition containing waste as a main component, an aggregate and a binder. A second step mixes the components of the initial composition dried in the first step. A third step adds water to the mixture obtained in the second step. A fourth step performs extrusion molding with the water-added mixture obtained in the third step. A fifth step fires an intermediate molding product obtained in the fourth step.

摘要翻译： 具有均匀孔结构的多孔陶瓷，其中具有在300〜4000nm的窄范围内的半径的孔占总孔容的90％以上。 多孔陶瓷通过包括干燥含有废物作为主要成分的初始组合物，骨料和粘合剂的第一步骤的方法制造。 第二步混合在第一步中干燥的初始组合物的组分。 第三步骤向第二步骤中获得的混合物中加入水。 第四步骤是用第三步骤获得的加水混合物进行挤出成型。 第五步骤是在第四步骤中获得的中间成型品。

公开(公告)号：US06810115B2

公开(公告)日：2004-10-26

申请号：US10188238

申请日：2002-07-03

申请人： Michiko Fukuda

发明人： Michiko Fukuda

IPC分类号： H04M156

CPC分类号： H04Q3/72 ,  H04M1/576 ,  H04M1/578 ,  H04M15/00 ,  H04M15/06 ,  H04Q2213/13034 ,  H04Q2213/13091 ,  H04Q2213/13096 ,  H04Q2213/13103 ,  H04Q2213/13174 ,  H04Q2213/13209 ,  H04Q2213/13292 ,  H04Q2213/13337

摘要： In a transmitting-side telephone apparatus 1 of a telephone system, a multimedia data multiplexing portion 108 multiplexes character data in a character data memory 101, image data in an image data memory 104, and music data in a music data memory 107 to produce multiplexed multimedia data to be memorized in a caller identification information holding memory 109 as caller identification information. A communication control information/caller identification information multiplexing portion 110 multiplexes communication control information from a transmission communication control portion 111 and the caller identification information from the caller identification information holding memory 109 to produce multiplexed transmission data to be transmitted through a transmitting portion 112. A receiving-side telephone apparatus of the telephone system demultiplexes the multiplexed transmission data and demultiplexes the caller identification information comprising the multiplexed multimedia data to produce unique expression based on the character data, the image data, and the music data.

摘要翻译： 在电话系统的发送侧电话装置1中，多媒体数据多路复用部分108将字符数据存储器101中的字符数据，图像数据存储器104中的图像数据和音乐数据存储器107中的音乐数据进行复用，以产生多路复用 要存储在呼叫者身份信息保持存储器109中的多媒体数据作为呼叫者识别信息。 通信控制信息/呼叫者识别信息多路复用部分110将来自发送通信控制部分111的通信控制信息和来自呼叫者识别信息保持存储器109的呼叫者识别信息进行复用，以产生将通过发送部分112发送的多路传输数据。 电话系统的接收侧电话设备对多路复用的传输数据进行解复用，并将包含复用的多媒体数据的呼叫者识别信息解复用，以产生基于字符数据，图像数据和音乐数据的唯一表达。

公开(公告)号：US09610359B2

公开(公告)日：2017-04-04

申请号：US13515930

申请日：2010-12-23

申请人： Michiko Fukuda ,  Kazuhiro Sugihara ,  Naohira Kanayama

发明人： Michiko Fukuda ,  Kazuhiro Sugihara ,  Naohira Kanayama

IPC分类号： A61K38/08 ,  A61K49/00 ,  C07K7/06 ,  A61P35/00 ,  A61K47/48

CPC分类号： A61K47/64

摘要： Disclosed are conjugates comprising the annexin 1-binding peptide IFLLWQR covalently linked to a therapeutic or detectable agent. Also disclosed are compositions comprising a moiety and a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Also disclosed are isolated nucleic acids comprising a nucleic acid sequence encoding a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Also disclosed are methods comprising administering to a subject a composition comprising a moiety and a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Also disclosed are methods of targeting a tumor cell in a subject comprising administering to the subject a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Also disclosed are methods of targeting a tumor cell in a subject comprising administering to the subject a composition comprising a moiety and a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. The disclosed targeting is useful for treatment of, for example, cancer.