Substituted 1,2,4-oxadiazole derivatives
    32.
    发明授权
    Substituted 1,2,4-oxadiazole derivatives 失效
    取代的1,2,4-恶二唑衍生物

    公开(公告)号:US5371231A

    公开(公告)日:1994-12-06

    申请号:US57584

    申请日:1993-05-05

    CPC classification number: C07D271/06 A01N43/82

    Abstract: The present invention relates to new substituted 1,2,4-oxadiazole derivatives of the formula (I) and to their stereoisomers ##STR1## in which formula R.sup.4 represents OH, SH, halogenoalkoxy, halogenoalkylthio, halogenoalkylsulphinyl, halogenoalkylsulphonyl, aryloxy, aralkoxy, arylthio, aralkylthio, alkylenedioxy, halogenoalkylenedioxy, amino, alkylamino, dialkylamino, acylamino, carbamoyl, alkylsulphinyl, alkylsulphonyl, arylsuphinyl, arylsulphonyl, sulphonylamino, alkoxycarbonyl, alkylcarbonyl, alkylcarbonyloxy, alkoxyalkyl, alkoxyalkoxy or hydroxyalkoxy, where in the event that at least one of the radicals R.sup.2 or R.sup.3 is other than hydrogen, R.sup.4 additionally represents halogen, alkyl, halogenoalkyl, alkoxy or thioalkyl, where, in the event that R.sup.1 represents optionally substituted C.sub.1-8 -alkyl, R.sup.4 additionally represents alkoxy,processes for their preparation, and their use as endoparasiticides.

    Abstract translation: 本发明涉及式(I)的新的取代的1,2,4-恶二唑衍生物及其立体异构体,其中式R4代表OH,SH,卤代烷氧基,卤代烷硫基,卤代烷基亚磺酰基,卤代烷基磺酰基,芳氧基, 芳烷氧基,芳硫基,芳烷硫基,亚烷基二氧基,卤代亚烷基二氧基,氨基,烷基氨基,二烷基氨基,酰基氨基,氨基甲酰基,烷基亚磺酰基,烷基磺酰基,芳基亚乙基,芳基磺酰基,磺酰基氨基,烷氧基羰基,烷基羰基,烷基羰基氧基,烷氧基烷基,烷氧基烷氧基或羟基烷氧基,其中在至少一个 基团R2或R3不是氢,R4另外表示卤素,烷基,卤代烷基,烷氧基或硫代烷基,其中,在R 1表示任选取代的C 1-8 - 烷基的情况下,R 4另外表示烷氧基,其制备方法, 并将其用作内寄生物杀灭剂。

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