公开(公告)号：US20140207010A1

公开(公告)日：2014-07-24

申请号：US14105749

申请日：2013-12-13

Applicant: Stuart O. Schecter

Inventor： Stuart O. Schecter

IPC: A61B5/11

CPC classification number: A61B5/1102 ,  A61B5/0031 ,  A61B5/029 ,  A61B8/08

Abstract: Cardiac tissue motion characteristics acquired by novel cardiac sensors are analyzed and processed for the derivation of physiological indices. The indices are output to a hand held local or remote volumetric haptic display and enable an operator to obtain motion related dynamic characteristics of cardiac tissues. The ability to tactually sense the motion of cardiac tissue and the affect on such motion from inserted cardiovascular instrumentation enhances the operator's performance of procedures including the positioning and placement of implanted catheters/sensors, extraction of permanently implanted leads and delivery of cardiovascular therapies. Optimal haptic rendering is achieved by using computational techniques to reconstruct the physically and perceptually relevant aspects of acquired signals and bridge the gap between the inserted catheter and operator's hand/catheter handle.

Abstract translation: 分析和处理由新型心脏传感器获得的心脏组织运动特征，用于推导生理指标。 指数输出到手持本地或远程体积触觉显示，并使操作者能够获得心脏组织的运动相关动态特征。 从插入的心血管仪器手术感觉心脏组织的运动和对这种运动的影响的能力增强了操作者的程序性能，包括植入的导管/传感器的定位和放置，永久植入的引线的提取和心血管疗法的递送。 通过使用计算技术来重建获取的信号的物理和感知相关方面并桥接插入的导管和操作者的手/导管手柄之间的间隙来实现最佳触觉渲染。

公开(公告)号：US20130321262A1

公开(公告)日：2013-12-05

申请号：US13837132

申请日：2013-03-15

Applicant: Stuart O. Schecter

Inventor： Stuart O. Schecter

IPC: G06F3/041

CPC classification number: G06F3/041 ,  A61B5/7455 ,  A61B18/1492 ,  A61B34/20 ,  A61B34/76 ,  A61B2017/00871 ,  A61B2018/00297 ,  A61B2018/00357 ,  A61B2018/00577 ,  A61B2034/301 ,  A61B2090/064 ,  G06F3/016 ,  G06F19/00

Abstract: A haptic system for a minimally invasive, hand-held surgical instrument and the system's various parts including a graphical user haptic interface, one or more haptic interfaces associated with a hand-held handle used to control a sensorized end-effector of the surgical instrument or inserted catheters, associated hardware, and an operating system. The system enables users to acquire, read, modify, store, write, and download sensor-acquired data in real time. The system can provide: an open, universally compatible platform capable of sensing or acquiring physiological signals/data in any format; processing of the sensor acquired data within an operating system; and outputting the processed signals to hardware which generates tangible sensations via one or more haptic interfaces. These tangible sensations can be modified by the user in real time as the system ensures the temporal relationship of sensed fiducial events are not altered or shifted relative to the generated and displayed haptic signals.

Abstract translation: 用于微创手持式手术器械的触觉系统，以及系统的各种部件，包括图形用户触觉界面，与用于控制手术器械的传感器末端执行器的手持手柄相关联的一个或多个触觉界面，或 插入的导管，相关联的硬件和操作系统。 该系统使用户实时获取，读取，修改，存储，写入和下载传感器采集的数据。 该系统可以提供：一个开放的，普遍兼容的平台，能够感测或获取任何格式的生理信号/数据; 在操作系统内处理传感器获取的数据; 并将经处理的信号输出到经由一个或多个触觉界面产生有形感觉的硬件。 这些有形感觉可以由用户实时修改，因为系统确保感测到的基准事件的时间关系相对于所生成和显示的触觉信号没有改变或移位。

公开(公告)号：US20130274712A1

公开(公告)日：2013-10-17

申请号：US13667644

申请日：2012-11-02

Applicant: Stuart O. Schecter

Inventor： Stuart O. Schecter

IPC: A61M25/10

CPC classification number: A61M25/10 ,  A61B5/026 ,  A61B5/0538 ,  A61B5/1107 ,  A61B5/6853 ,  A61B5/7455 ,  A61B18/02 ,  A61B34/35 ,  A61B34/76 ,  A61B2017/00075 ,  A61B2018/00303 ,  A61B2018/00351 ,  A61B2018/00839 ,  A61B2018/0088 ,  A61B2018/0212 ,  A61B2562/0219 ,  A61B2562/0247 ,  A61B2562/028 ,  A61M25/0097

Abstract: Embodiments of this invention include hand-held handles and systems for balloon-tipped catheter interventions that enable a user to appreciate a combination of palpable sensations as though his or her hand is actual anatomic tissue in situ in real time. The system may include a haptic handle coupled to the proximal end of the catheter where the haptic handle includes a balloon-shaped haptic interface that exhibits geometric characteristics reflecting an anatomy of the interventional balloon and provides tangible sensations representative of tissues surrounding the interventional balloon. Multiple sensors and actuators may be used to create a non-virtual, transparent experience communicated to a user with a three dimensional, volumetric haptic display. In one embodiment, the sensors are positioned about or within an inflatable balloon positioned at the distal aspect of an inserted catheter used to treat cardiac and vascular diseases such as coronary or peripheral vascular occlusion and ablation of cardiac tissue.

Abstract translation: 本发明的实施例包括用于球囊导管干预的手持手柄和系统，其使用户能够欣赏可触觉感觉的组合，就像他或她的手实际上是实际的实际解剖组织。 该系统可以包括耦合到导管的近端的触觉手柄，其中触觉手柄包括气球形触觉界面，其呈现反映介入气囊的解剖结构的几何特征，并且提供代表介入气囊周围的组织的有形感觉。 可以使用多个传感器和致动器来创建用三维，体积触觉显示传达给用户的非虚拟的，透明的体验。 在一个实施例中，传感器被定位在位于用于治疗心脏和血管疾病例如冠状动脉或血管周围血管闭塞和心脏组织消融的插入导管的远侧方面的可充气气囊周围或内部。

公开(公告)号：US08214039B1

公开(公告)日：2012-07-03

申请号：US11539837

申请日：2006-10-09

Applicant: Stuart O. Schecter

Inventor： Stuart O. Schecter

IPC: A61N1/00

CPC classification number: G06F8/4451 ,  A61B5/04525 ,  A61N1/3627 ,  A61N1/36521

Abstract: A method of determining pacing therapy for an individual patient including determining representative electromechanical physiologic characteristics for a plurality of normal patients having a range of anatomical dimensions and developing a plurality of normal templates. Each template indicates the representative electromechanical physiologic characteristics of a group of normal patients having similar anatomical dimensions. The method can include measuring the anatomical dimensions of a dysfunctional patient, matching the dysfunctional patient with a template for normal patients having similar anatomical dimensions as the dysfunctional patient, determining the physiologic characteristics for the dysfunctional patient, determining indicated correction factors corresponding to any differences between the dysfunctional patient's physiologic characteristics and those of the matched template, and adjusting therapy delivery by any indicated correction factors to stimulate the patient in a pattern more closely matched to the physiologic characteristics of the matched template.

Abstract translation: 一种确定个体患者的起搏治疗的方法，包括确定具有解剖尺寸范围的多个正常患者的代表性机电生理特​​征，并开发多个正常模板。 每个模板指示具有相似解剖尺寸的一组正常患者的代表性机电生理特​​征。 该方法可以包括测量功能障碍患者的解剖尺寸，使功能障碍患者与具有与功能障碍患者相似的解剖尺寸的正常患者的模板匹配，确定功能障碍患者的生理特征，确定对应于任何差异的指示的校正因子 功能障碍患者的生理特征和匹配模板的生理特征，以及通过任何指示的校正因子调整治疗递送，以以与匹配模板的生理特征更接近的模式刺激患者。

公开(公告)号：US20110306890A1

公开(公告)日：2011-12-15

申请号：US13191253

申请日：2011-07-26

Applicant: Stuart O. Schecter ,  Kjell Noren

Inventor： Stuart O. Schecter ,  Kjell Noren

IPC: A61N1/365 ,  A61B5/024

CPC classification number: A61N1/36514 ,  A61N1/36578

Abstract: A first lead provides therapeutic stimulation to the heart and includes a first mechanical sensor that measures physical contraction and relaxation of the heart. A controller induces delivery of therapeutic stimulation via the first lead. The controller receives signals from the first mechanical sensor indicative of the contraction and relaxation; develops a template signal that corresponds to the contraction and relaxation; and uses the template signal to modify the delivery of therapeutic stimulations. In another arrangement, a second lead, with a second mechanical sensor also provides signals to the controller indicative of contraction and relaxation. The first mechanical sensor is adapted to be positioned at the interventricular septal region of the heart, and the second mechanical sensor is adapted to be positioned in the lateral region of the left ventricle. The controller processes the signals from the first mechanical sensor and the second mechanical sensor to develop a dysynchrony index.

Abstract translation: 第一个引线提供对心脏的治疗刺激，并且包括测量心脏的身体收缩和松弛的第一机械传感器。 控制器通过第一引线诱导治疗性刺激。 控制器从第一机械传感器接收指示收缩和松弛的信号; 开发对应于收缩和放松的模板信号; 并使用模板信号修改治疗刺激的递送。 在另一种布置中，具有第二机械传感器的第二引线还向控制器提供指示收缩和松弛的信号。 第一机械传感器适于定位在心脏的室间隔区域，并且第二机械传感器适于定位在左心室的侧向区域中。 控制器处理来自第一机械传感器和第二机械传感器的信号以产生异步指数。

公开(公告)号：US08014864B2

公开(公告)日：2011-09-06

申请号：US12140862

申请日：2008-06-17

Applicant: Stuart O. Schecter ,  Kjell Noren

Inventor： Stuart O. Schecter ,  Kjell Noren

IPC: A61N1/08

CPC classification number: A61N1/36514 ,  A61N1/36578

Abstract: A first lead provides therapeutic stimulation to the heart and includes a first mechanical sensor that measures physical contraction and relaxation of the heart. A controller induces delivery of therapeutic stimulation via the first lead. The controller receives signals from the first mechanical sensor indicative of the contraction and relaxation; develops a template signal that corresponds to the contraction and relaxation; and uses the template signal to modify the delivery of therapeutic stimulations. In another arrangement, a second lead, with a second mechanical sensor also provides signals to the controller indicative of contraction and relaxation. The first mechanical sensor is adapted to be positioned at the interventricular septal region of the heart, and the second mechanical sensor is adapted to be positioned in the lateral region of the left ventricle. The controller processes the signals from the first mechanical sensor and the second mechanical sensor to develop a dysynchrony index.

Abstract translation: 第一个引线提供对心脏的治疗刺激，并且包括测量心脏的身体收缩和松弛的第一机械传感器。 控制器通过第一引线诱导治疗性刺激。 控制器从第一机械传感器接收指示收缩和松弛的信号; 开发对应于收缩和放松的模板信号; 并使用模板信号修改治疗刺激的递送。 在另一种布置中，具有第二机械传感器的第二引线还向控制器提供指示收缩和松弛的信号。 第一机械传感器适于定位在心脏的室间隔区域，并且第二机械传感器适于定位在左心室的侧向区域中。 控制器处理来自第一机械传感器和第二机械传感器的信号以产生异步指数。

公开(公告)号：US07970469B2

公开(公告)日：2011-06-28

申请号：US12788003

申请日：2010-05-26

Applicant: Stuart O. Schecter

Inventor： Stuart O. Schecter

IPC: A61N1/365

CPC classification number: A61N1/3627 ,  A61B5/0031 ,  A61B5/0452 ,  A61B5/05 ,  A61B5/7285 ,  A61N1/36521 ,  A61N1/36585 ,  A61N1/3682 ,  A61N1/37247

Abstract: An implantable therapy system including implantable stimulation and control components. The implantable components operate under a set of variable parameters that can be adjusted for improved performance for an individual patient. The implantable components are adapted to self-evaluate the patients physiologic performance and autonomously adjust an existing set of parameters to improve performance throughout an implantation period without requiring intervention of a clinician, for example with a physicians programmer. The implantable components can compare a patient's exhibited activity to a desired template of that activity to determine when adjustments are indicated. The template can be based on observations of one or more third parties exhibiting normal activity. The implantable components can adjust the operating parameters to improve synchrony of multiple heart chambers and/or to increase a peak contractility.

Abstract translation: 一种植入式治疗系统，包括可植入的刺激和控制组件。 可植入组件在一组可变参数下操作，可以针对单个患者进行调整以改善性能。 可植入组件适于自我评估患者的生理表现并自主地调整现有参数集以改善整个植入期间的性能，而不需要例如与医生程序员的临床医生的干预。 可植入组件可以将患者的展示活动与该活动的期望模板进行比较，以确定何时显示调整。 模板可以基于一个或多个表现正常活动的第三方的观察结果。 可植入部件可以调整操作参数以改善多个心室的同步和/或增加峰值收缩性。

公开(公告)号：US20100152795A1

公开(公告)日：2010-06-17

申请号：US12332725

申请日：2008-12-11

Applicant: Stuart O. Schecter

Inventor： Stuart O. Schecter

IPC: A61N1/39 ,  A61N1/368

CPC classification number: A61N1/3627 ,  A61N1/3702

Abstract: Implantable stimulation devices can provide intracardiac electrograms (EGMs) and impedance measurements to detect changes in electrical, mechanical, and electromechanical activation of the heart. Many patients with congestive heart failure have conventional intracardiac devices implanted that are not capable of resynchronization therapy and these patients could benefit from resynchronization, but are not candidates based on current criteria. These patient populations can be identified through analyses of intracardiac electrogram data that is available through implantable stimulation devices comprising at least one lead for providing electrical stimulation to the heart of a patient, at least one sensor that detects electrical signals indicative of the depolarization of the heart of the patient, and a controller that is adapted to be implanted within the patient. The controller receives signals from the at least one sensor and further induces the lead to provide therapeutic electrical stimulation to the heart of the patient. The controller periodically evaluates the signals from the sensor and determines if at least one parameter of the signal is indicative of the patient being potentially subject to heart dysynchrony. The controller, upon determining that the parameter of the signal indicates that the patient is potentially subject to heart dysynchrony, records an indication thereof for subsequent communication to treating medical personnel.

Abstract translation: 植入式刺激装置可以提供心内电描记图（EGM）和阻抗测量，以检测心脏的电，机械和机电激活的变化。 许多患有充血性心力衰竭的患者具有植入的常规心脏手术，不能进行再同步治疗，并且这些患者可以受益于再同步，但不是基于当前标准的候选者。 可以通过分析心脏电图数据来识别这些患者群体，所述心脏电图数据可通过可植入刺激装置获得，所述植入式刺激装置包括至少一个引线，用于向患者的心脏提供电刺激，至少一个传感器，其检测指示心脏去极化的电信号 以及适于植入患者体内的控制器。 所述控制器接收来自所述至少一个传感器的信号，并进一步诱导所述引线向患者的心脏提供治疗性电刺激。 控制器周期性地评估来自传感器的信号，并确定信号的至少一个参数是否指示患者可能受心脏异常的影响。 控制器在确定信号的参数指示患者可能患有心脏异常时，记录其后续通信的指示以处理医疗人员。

公开(公告)号：US20100121403A1

公开(公告)日：2010-05-13

申请号：US12267376

申请日：2008-11-07

Applicant: Stuart O. Schecter ,  Xiaoyi Min

Inventor： Stuart O. Schecter ,  Xiaoyi Min

IPC: A61N1/37

CPC classification number: A61N1/368 ,  A61B5/0452 ,  A61B5/0538 ,  A61N1/3627 ,  A61N1/36521 ,  A61N1/3684 ,  A61N1/3702

Abstract: An implantable cardiac therapy device and methods of using a device including an implantable stimulation pulse generator, one or more implantable leads defining sensing and stimulation circuits adapted to sense and deliver therapy in at least one right side heart chamber, and an implantable controller in communication with the stimulation pulse generator and the one or more patient leads so as to receive sensed signals indicative of a patient's physiologic activity and deliver indicated therapy. The controller is adapted to monitor at least one indicator of cardiac dysynchrony and to compare the at least one indicator to a determined dysynchrony threshold. The threshold is determined for indications that the patient be further evaluated for cardiac resynchronization therapy. The controller is further adapted to set an alert when the at least one indicator exceeds the threshold to indicate to a clinician that evaluation for bi-ventricular pacing might be indicated.

Abstract translation: 一种可植入心脏治疗装置和使用包括可植入刺激脉冲发生器的装置的方法，一种或多种可植入引线，其限定适于在至少一个右侧心室中感测和递送治疗的感测和刺激电路，以及可植入控制器，与 刺激脉冲发生器和一个或多个患者引线，以便接收指示患者的生理活动的感测信号并递送指示的治疗。 控制器适于监测至少一个心脏异常的指示器，并将该至少一个指示符与确定的不同步阈值进行比较。 确定阈值以进一步评估患者心脏再同步治疗的适应症。 所述控制器还适于当所述至少一个指示符超过所述阈值时设置警报，以向临床医生指示可能指示对于双心室起搏的评估。

公开(公告)号：US20090312814A1

公开(公告)日：2009-12-17

申请号：US12140862

申请日：2008-06-17

Applicant: Stuart O. Schecter ,  Kjell Noren

Inventor： Stuart O. Schecter ,  Kjell Noren

IPC: A61N1/365

CPC classification number: A61N1/36514 ,  A61N1/36578

Abstract: A first lead provides therapeutic stimulation to the heart and includes a first mechanical sensor that measures physical contraction and relaxation of the heart. A controller induces delivery of therapeutic stimulation via the first lead. The controller receives signals from the first mechanical sensor indicative of the contraction and relaxation; develops a template signal that corresponds to the contraction and relaxation; and uses the template signal to modify the delivery of therapeutic stimulations. In another arrangement, a second lead, with a second mechanical sensor also provides signals to the controller indicative of contraction and relaxation. The first mechanical sensor is adapted to be positioned at the interventricular septal region of the heart, and the second mechanical sensor is adapted to be positioned in the lateral region of the left ventricle. The controller processes the signals from the first mechanical sensor and the second mechanical sensor to develop a dysynchrony index.

Abstract translation: 第一个引线提供对心脏的治疗刺激，并且包括测量心脏的身体收缩和松弛的第一机械传感器。 控制器通过第一引线诱导治疗性刺激。 控制器从第一机械传感器接收指示收缩和松弛的信号; 开发对应于收缩和放松的模板信号; 并使用模板信号修改治疗刺激的递送。 在另一种布置中，具有第二机械传感器的第二引线还向控制器提供指示收缩和松弛的信号。 第一机械传感器适于定位在心脏的室间隔区域，并且第二机械传感器适于定位在左心室的侧向区域中。 控制器处理来自第一机械传感器和第二机械传感器的信号以产生异步指数。