公开(公告)号：US20090137411A1

公开(公告)日：2009-05-28

申请号：US10593908

申请日：2005-03-28

Applicant: Yimin Sun ,  Wanli Xing ,  Guoqing Wang ,  Hongwu Du ,  Rong Zhang ,  Yuan Lu ,  Yan Wang ,  Jing Cheng

Inventor： Yimin Sun ,  Wanli Xing ,  Guoqing Wang ,  Hongwu Du ,  Rong Zhang ,  Yuan Lu ,  Yan Wang ,  Jing Cheng

IPC: C40B30/04 ,  C40B40/04 ,  C40B50/18

CPC classification number: G01N33/543 ,  B01J2219/00387 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00621 ,  B01J2219/00626 ,  B01J2219/00659 ,  B01J2219/0072 ,  C40B60/14 ,  G01N33/54366

Abstract: The present invention discloses methods for detection of small molecule compounds and its specific biochips. Biochips of the present invention comprise a solid support and carrier-linked small molecules immobilized onto the solid support. The invention also provides methods and kits for detection of small molecule compounds using the biochips of the invention.

Abstract translation: 本发明公开了小分子化合物及其特定生物芯片的检测方法。 本发明的生物芯片包含固体支持物和固定在固体支持物上的载体连接的小分子。 本发明还提供了使用本发明的生物芯片检测小分子化合物的方法和试剂盒。

公开(公告)号：US07527719B2

公开(公告)日：2009-05-05

申请号：US10500180

申请日：2002-11-29

Applicant: Peng Liu ,  Wanli Xing ,  Dong Liang ,  Jing Cheng

Inventor： Peng Liu ,  Wanli Xing ,  Dong Liang ,  Jing Cheng

IPC: G01N27/453

CPC classification number: G01N27/44791

Abstract: The present invention provides a capillary electrophoresis chip apparatus for detecting nucleotide polymorphism or single nucleotide polymorphism belonging to capillary electrophoresis apparatuses. The apparatus comprises an upper channel layer comprising a one-, two-, or multi-dimensional microfluid channel and an electrode aperture structure for loading sample, a middle electrode layer for sealing the microfluid channel to form an intact capillary and providing the needed voltage for electrophoresis; and a lower heating layer for providing a stable temperature gradient for electrophoresis. The upper, middle and lower layers are thermal conductive and adhesive to each other.

Abstract translation: 本发明提供一种用于检测属于毛细管电泳装置的核苷酸多态性或单核苷酸多态性的毛细管电泳芯片装置。 该装置包括上通道层，其包括一维，二维或多维微流体通道和用于装载样品的电极孔结构，用于密封微流体通道以形成完整毛细管的中间电极层，并提供所需电压 电泳; 以及用于提供电泳的稳定温度梯度的较低加热层。 上，中，下层相互导热，粘合。

公开(公告)号：US20060144237A1

公开(公告)日：2006-07-06

申请号：US10537533

申请日：2002-12-31

Applicant: Dong Liang ,  Wanli Xing ,  Jing Cheng

Inventor： Dong Liang ,  Wanli Xing ,  Jing Cheng

IPC: B01D53/02 ,  B01D53/14

CPC classification number: G01N30/6095 ,  G01N30/6039 ,  G01N2030/025

Abstract: This invention relates to the field of miniaturing gas chromatograph instruments using microfabrication technologies. In particular, the invention provides a gas chromatograph column, which column comprises at least two lid layers and a channel layer, wherein each of said layers comprises a compact material suitable for gas chromatograph, said channel layer comprises microfabricated channels on both sides, said microfabricated channels and a side of said lid layers form at least two capillaries, said at least two capillaries are connected to each other through a hole in said channel layer to form an integrated capillary, said integrated capillary is connected to outside atmosphere on both ends via holes on two outmost lid layers to serve as an inlet and an outlet.

Abstract translation: 本发明涉及使用微细加工技术的微型气相色谱仪的领域。 特别地，本发明提供了一种气相色谱柱，该色谱柱包括至少两个盖层和沟道层，其中每个所述层包括适合于气相色谱的致密材料，所述通道层包括两侧的微细加工通道，所述微制造 通道和所述盖层的一侧形成至少两个毛细管，所述至少两个毛细管通过所述通道层中的孔彼此连接以形成集成毛细管，所述集成毛细管连接到两端的外部大气通孔 在两个最外层的盖层上用作入口和出口。

公开(公告)号：US20050106708A1

公开(公告)日：2005-05-19

申请号：US10499098

申请日：2002-11-29

Applicant: Wanli Xing ,  Zhe Yu ,  Guangxin Xiang ,  Liangbin Pan ,  Jing Cheng

Inventor： Wanli Xing ,  Zhe Yu ,  Guangxin Xiang ,  Liangbin Pan ,  Jing Cheng

IPC: C12M1/42 ,  C12M1/34 ,  C12N13/00 ,  C12Q1/02 ,  G01N33/543 ,  G01F1/64

CPC classification number: G01N33/5438 ,  C12M35/02 ,  G01N2333/46 ,  G01N2500/10

Abstract: The present invention provides an apparatus for stimulating an animal cell and recording its physiological signal and methods of making and using thereof. The purpose of the present invention is to provide an apparatus for stimulating an animal cell and recording its physiological signal that is efficient, convenient, and accurate. The apparatus for stimulating an animal cell and recording its physiological signal of the present invention comprises a poor conductive substrate, wherein on at least one surface of the substrate is provided at least one unit conductive polymer layer and at least one good conductive microelectrode.

Abstract translation: 本发明提供一种用于刺激动物细胞并记录其生理信号的装置及其制造和使用方法。 本发明的目的是提供一种用于刺激动物细胞并记录其生理信号的装置，其有效，方便和准确。 用于刺激动物细胞并记录其本发明的生理信号的装置包括差的导电基底，其中在基底的至少一个表面上提供至少一个单位导电聚合物层和至少一个良好的导电微电极。