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    Closed loop deep brain stimulation systems and methods
    32.
    发明授权
    Closed loop deep brain stimulation systems and methods 有权

    公开(公告)号：US11224747B2

    公开(公告)日：2022-01-18

    申请号：US16708878

    申请日：2019-12-10

    Applicant: Battelle Memorial Institute

    Inventor： Chad E. Bouton ,  Gaurav Sharma ,  Bradley C. Glenn

    IPC: A61B5/374 ,  A61N1/36 ,  A61B5/291 ,  A61B5/316 ,  A61B5/375 ,  A61B5/00 ,  A61N1/05

    Abstract: The present disclosure relates generally to systems, methods, and devices for closed loop deep brain stimulation. In particular, a neural signal is measured and provided to software. The software includes a feature generator and a brain network model that takes the neural signal and estimates other neural signals that are not directly measured, and operates as a model of the brain. The software determines a stimulation signal to be sent to stimulating electrodes. Estimated signals by the brain network model are continuously compared to actual signals from the brain. The closed loop feedback system advantageously allows for electrical stimulation levels and patterns to be continuously updated while delivered to a patient.

    NEUROSTIMULATION OR ELECTROMYOGRAPHY CUFF
    33.
    发明申请
    NEUROSTIMULATION OR ELECTROMYOGRAPHY CUFF 有权

    公开(公告)号：US20210187279A1

    公开(公告)日：2021-06-24

    申请号：US17196082

    申请日：2021-03-09

    Applicant: Battelle Memorial Institute

    Inventor： Chad E. Bouton ,  Jeffrey Friend

    IPC: A61N1/04 ,  A61N1/36 ,  H05K3/10

    Abstract: The present disclosure describes systems, methods, devices for performing thought-controlled neuromuscular stimulation. Also described are methods for producing a neuromuscular stimulation cuff. The systems and methods generally relate to receiving and processing thought signals indicative of an intended action, and then delivering stimulation to effectuate the intended action through a neuromuscular stimulation cuff. The neuromuscular stimulation cuff includes a flexible printed circuit board having at least one finger and a plurality of electrogel discs disposed on the at least one finger. The neuromuscular stimulation cuff may be produced by providing a layer of polyimide, etching a conductive copper circuit including a plurality of electrodes into the layer of polyimide to form an etched circuit layer, adhering a cover layer onto the etched circuit layer to form a flexible printed circuit board (PCB), and cutting at least one finger from the flexible PCB. The neuromuscular stimulation cuff employs a flexible multi-electrode design which allows for reanimation of complex muscle movements in a patient, including individual finger movement.

    EXTRAVASATION AND INFILTRATION DETECTION DEVICE
    34.
    发明申请
    EXTRAVASATION AND INFILTRATION DETECTION DEVICE 有权

    公开(公告)号：US20210030302A1

    公开(公告)日：2021-02-04

    申请号：US17072428

    申请日：2020-10-16

    Applicant: Battelle Memorial Institute

    Inventor： Chad E. Bouton

    IPC: A61B5/05 ,  A61M5/168 ,  A61B5/053 ,  A61B8/08 ,  A61B5/00

    Abstract: An integrated device of a patch and sensor assembly detects extravasation or infiltration. A transmitter is positioned to direct power into a body portion. A sensor is positioned to receive the power transmitted through the body portion. A substrate is attachable to an outer surface of the body portion and supports the transmitter and the sensor. A signal processor is coupled to the transmitter and the sensor for detecting a change in a fluid level in the body portion from extravasation or infiltration based on the power received by the sensor. A power supply is coupled to the transmitter and the sensor. An indicator is responsive to the signal processor to indicate a detected change in a fluid level in the body portion from extravasation or infiltration.

    Closed loop deep brain stimulation systems and methods
    36.
    发明授权
    Closed loop deep brain stimulation systems and methods 有权

    公开(公告)号：US10525267B2

    公开(公告)日：2020-01-07

    申请号：US15578783

    申请日：2016-06-02

    Applicant: Battelle Memorial Institute

    Inventor： Chad E. Bouton ,  Gaurav Sharma ,  Bradley C. Glenn

    IPC: A61B5/00 ,  A61N1/36 ,  A61B5/04 ,  A61B5/0478 ,  A61B5/048 ,  A61B5/0482 ,  A61N1/05

    Abstract: The present disclosure relates generally to systems, methods, and devices for closed loop deep brain stimulation. In particular, a neural signal is measured and provided to software. The software includes a feature generator and a brain network model that takes the neural signal and estimates other neural signals that are not directly measured, and operates as a model of the brain. The software determines a stimulation signal to be sent to stimulating electrodes. Estimated signals by the brain network model are continuously compared to actual signals from the brain. The closed loop feedback system advantageously allows for electrical stimulation levels and patterns to be continuously updated while delivered to a patient.

    SYSTEMS INCLUDING NEUROMUSCULAR STIMULATION CUFF
    37.
    发明申请
    SYSTEMS INCLUDING NEUROMUSCULAR STIMULATION CUFF 审中-公开

    公开(公告)号：US20190224473A1

    公开(公告)日：2019-07-25

    申请号：US16371417

    申请日：2019-04-01

    Applicant: Battelle Memorial Institute

    Inventor： Chad E. Bouton ,  Jeffrey Friend

    IPC: A61N1/04 ,  H05K3/10 ,  A61N1/36

    Abstract: The present disclosure describes systems, methods, devices for performing thought-controlled neuromuscular stimulation. Also described are methods for producing a neuromuscular stimulation cuff. The systems and methods generally relate to receiving and processing thought signals indicative of an intended action, and then delivering stimulation to effectuate the intended action through a neuromuscular stimulation cuff. The neuromuscular stimulation cuff includes a flexible printed circuit board having at least one finger and a plurality of electrogel discs disposed on the at least one finger. The neuromuscular stimulation cuff may be produced by providing a layer of polyimide, etching a conductive copper circuit including a plurality of electrodes into the layer of polyimide to form an etched circuit layer, adhering a cover layer onto the etched circuit layer to form a flexible printed circuit board (PCB), and cutting at least one finger from the flexible PCB. The neuromuscular stimulation cuff employs a flexible multi-electrode design which allows for reanimation of complex muscle movements in a patient, including individual finger movement.

    NEUROMUSCULAR STIMULATION CUFF
    40.
    发明申请
    NEUROMUSCULAR STIMULATION CUFF 有权
    神经刺激灶

    公开(公告)号：US20150290451A1

    公开(公告)日：2015-10-15

    申请号：US14649025

    申请日：2013-12-05

    Applicant: BATTELLE MEMORIAL INSTITUTE

    Inventor： Chad E. Bouton ,  Jeffrey Friend

    IPC: A61N1/04 ,  H05K3/10 ,  A61N1/36

    CPC classification number: A61N1/0484 ,  A61N1/0452 ,  A61N1/0456 ,  A61N1/0476 ,  A61N1/0492 ,  A61N1/36003 ,  A61N1/36014 ,  H05K3/10

    Abstract: The present disclosure describes systems, methods, devices for performing thought-controlled neuromuscular stimulation. Also described are methods for producing a neuromuscular stimulation cuff. The systems and methods generally relate to receiving and processing thought signals indicative of an intended action, and then delivering stimulation to effectuate the intended action through a neuromuscular stimulation cuff. The neuromuscular stimulation cuff includes a flexible printed circuit board having at least one finger and a plurality of electrogel discs disposed on the at least one finger. The neuromuscular stimulation cuff may be produced by providing a layer of polyimide, etching a conductive copper circuit including a plurality of electrodes into the layer of polyimide to form an etched circuit layer, adhering a cover layer onto the etched circuit layer to form a flexible printed circuit board (PCB), and cutting at least one finger from the flexible PCB. The neuromuscular stimulation cuff employs a flexible multi-electrode design which allows for reanimation of complex muscle movements in a patient, including individual finger movement.

    Abstract translation: 本公开描述了用于执行思维控制的神经肌肉刺激的系统，方法，装置。 还描述了用于产生神经肌肉刺激袖带的方法。 系统和方法通常涉及接收和处理指示预期动作的思维信号，然后传递刺激以通过神经肌肉刺激袖带来实现预期的动作。 神经肌肉刺激套囊包括具有至少一个手指的柔性印刷电路板和设置在至少一个手指上的多个电凝胶盘。 神经肌肉刺激袖口可以通过提供一层聚酰亚胺，将包括多个电极的导电铜电路蚀刻到聚酰亚胺层中以形成蚀刻电路层，将覆盖层粘附到蚀刻电路层上以形成柔性印刷 电路板（PCB），并从柔性PCB切割至少一根手指。 神经肌肉刺激袖口使用灵活的多电极设计，其允许对患者中的复杂肌肉运动进行再动作，包括单独的手指运动。

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