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155 条记录 (耗时 0.03 秒)

    Double cone-like crystal form of 2-amino-6-chloropurine and preparation
    32.
    发明授权
    Double cone-like crystal form of 2-amino-6-chloropurine and preparation 失效
    双锥形晶体形式的2-氨基-6-氯嘌呤及其制备方法

    公开(公告)号：US5789590A

    公开(公告)日：1998-08-04

    申请号：US741223

    申请日：1996-10-29

    申请人： Masatoshi Sakai ,  Masaki Fujiwara ,  Toshio Nakamatsu

    发明人： Masatoshi Sakai ,  Masaki Fujiwara ,  Toshio Nakamatsu

    IPC分类号： C07D473/40

    CPC分类号： C07D473/40

    摘要： The present invention is directed to a method for preparing 2-amino-6-chloropurine having a double cone-like crystal form, comprising the steps of: (A) suspending 2-amino-6-chloropurine having an acicular or irregular-shaped crystal form in a liquid consisting essentially of water having a pH of from 3 to 10; and (B) heating the resulting suspension at a temperature of from 70.degree. to 100.degree. C. to complete the double cone-like crystal form conversion.

    摘要翻译： 本发明涉及一种制备具有双锥状晶体形式的2-氨基-6-氯嘌呤的方法，包括以下步骤：（A）悬浮具有针状或不规则形状晶体的2-氨基-6-氯嘌呤 在基本上由pH为3至10的水组成的液体中形成; 和（B）在70℃至100℃的温度下加热得到的悬浮液以完成双锥状晶体形式的转化。

    Document producing apparatus having in-document layout display
    34.
    发明授权
    Document producing apparatus having in-document layout display 失效
    具有文件内布局显示的文件制作装置

    公开(公告)号：US4951233A

    公开(公告)日：1990-08-21

    申请号：US227891

    申请日：1988-08-03

    申请人： Masaki Fujiwara ,  Masaki Kawase ,  Kiyoshi Masuda ,  Shigeki Taniguchi

    发明人： Masaki Fujiwara ,  Masaki Kawase ,  Kiyoshi Masuda ,  Shigeki Taniguchi

    IPC分类号： G06F17/21

    CPC分类号： G06F17/212

    摘要： A document producing apparatus comprises an input unit for inputting descriptive contents such as characters or figures which contstruct a document and a format which defines a sheet size of a paper sheet used, a sheet direction of portrait or landscape in which the sheet is to be used, and a layout of the descriptive contents in each page, a storage unit for storing therein the descriptive contents and the format inputted from the input unit, a display unit for selectively displaying the contents stored in the storage unit, and an in-document layout editing unit for displaying on the display unit a layout of a plurality of pages forming the document so that page information of the respective pages are partitioned in due order from a leading page and for every predetermined number of pages and are arranged in one display image, the page information including at least the sheet size and the sheet direction stored in the storage unit. The apparatus may further comprise a page editing unit for performing the editing for a desired page while referring to a display image displayed on the display unit.

    摘要翻译： 文件制作装置包括：输入单元，用于输入描述内容，例如文字的图形或图形，以及定义所使用的纸张的纸张尺寸的格式，使用纸张的纵向或横向的纸张方向 以及每个页面中的描述内容的布局;存储单元，用于在其中存储描述内容和从输入单元输入的格式;用于选择性地显示存储在存储单元中的内容的显示单元和文档内容布局 编辑单元，用于在所述显示单元上显示形成所述文档的多个页面的布局，使得各页面的页面信息按照顺序从前页和每预定页数被分割并排列在一个显示图像中， 页面信息至少包括存储在存储单元中的纸张尺寸和纸张方向。 该装置还可以包括页面编辑单元，用于在参考显示在显示单元上的显示图像的同时执行所需页面的编辑。

    Lubricator
    35.
    发明授权
    Lubricator 失效
    润滑油

    公开(公告)号：US4721186A

    公开(公告)日：1988-01-26

    申请号：US850563

    申请日：1986-04-11

    申请人： Masaki Fujiwara

    发明人： Masaki Fujiwara

    IPC分类号： F16N7/34 ,  F01M1/08

    CPC分类号： F16N7/34 ,  Y10T137/3112

    摘要： A lubricator includes a body having a passage for a fluid under pressure, at least one hole communicating perpendicularly to the passage, and a restriction member fitted in the hole and positionable in the passage, a case securely mounted on the body and having a chamber communicating with the passage and capable of storing oil, and a dropping window communicating with the chamber through an oil conduit tube and a dropping tube and also communicating through a passageway with the passage downstream of the restriction members in the direction of flow of the fluid through the passage.

    摘要翻译： 润滑器包括：本体，其具有用于压力下的流体的通道，至少一个垂直于该通道连通的孔;以及限制构件，其安装在孔中并且可定位在通道中;壳体，牢固地安装在主体上， 具有通道并且能够储存油，以及通过油导管和下放管与室连通的下落窗，并且还通过通道与限流构件下游的通道在流体流动方向上连通通过 通道。

    Method for measuring hematocrit value of blood sample, method for measuring concentration of analyte in blood sample, sensor chip and sensor unit
    37.
    发明授权
    Method for measuring hematocrit value of blood sample, method for measuring concentration of analyte in blood sample, sensor chip and sensor unit 有权
    测定血液样品血细胞比容值的方法，血样中分析物浓度测定方法，传感器芯片和传感器单元

    公开(公告)号：US08691072B2

    公开(公告)日：2014-04-08

    申请号：US12377514

    申请日：2007-10-17

    申请人： Masaki Fujiwara ,  Shin Ikeda ,  Takahiro Nakaminami

    发明人： Masaki Fujiwara ,  Shin Ikeda ,  Takahiro Nakaminami

    IPC分类号： G01N27/26

    CPC分类号： G01N27/3274 ,  G01N27/3272 ,  G01N27/413

    摘要： Voltage is applied across a counter electrode and a working electrode, with which a blood sample is in contact, in such a state that an oxidant in a redox substance is not substantially in contact with a working electrode but is in contact with a counter electrode and a reductant is not substantially in contact with the counter electrode but is in contact with the working electrode, whereby the reductant and the oxidant are respectively oxidized and reduced to measure current produced upon the oxidation and reduction. According to the above constitution, while lowering the voltage applied across the working electrode and the counter electrode, the Hct value of the blood sample can be measured stably with a satisfactory detection sensitivity. This measurement can be carried out with a sensor chip comprising a working electrode (11), a counter electrode (12), and a blood sample holding part (14) having branch parts (18a, 18b). A first reagent (13) consisting essentially of an oxidant in a redox substance is disposed in contact with the surface of a counter electrode which faces the branch part (18b), and a second reagent (19) consisting essentially of a reductant is disposed in contact with the surface of a working electrode that faces the branch part (18a).

    摘要翻译： 在氧化还原物质中的氧化剂基本上不与工作电极接触但与对电极接触的状态下，跨越对置电极和与血液样品接触的工作电极施加电压， 还原剂基本上不与对电极接触，而是与工作电极接触，由此还原剂和氧化剂分别被氧化和还原，以测量在氧化和还原时产生的电流。 根据上述结构，在降低施加在工作电极和对电极两端的电压的同时，能够以良好的检测灵敏度稳定地测定血液样品的Hct值。 该测量可以用包括工作电极（11），对电极（12）和具有分支部分（18a，18b）的血液样本保持部分（14）的传感器芯片进行。 基本上由氧化还原物质中的氧化剂组成的第一试剂（13）被设置成与面对分支部分（18b）的对电极的表面接触，并且基本上由还原剂组成的第二试剂（19）设置在 与面向分支部（18a）的工作电极的表面接触。

    Method of measuring blood component, sensor used in the method, and measuring device
    38.
    发明授权
    Method of measuring blood component, sensor used in the method, and measuring device 有权

    公开(公告)号：US08535497B2

    公开(公告)日：2013-09-17

    申请号：US10578275

    申请日：2004-12-03

    申请人： Masaki Fujiwara ,  Teppei Shinno ,  Shin Ikeda

    发明人： Masaki Fujiwara ,  Teppei Shinno ,  Shin Ikeda

    IPC分类号： G01N27/327

    CPC分类号： G01N27/3274 ,  C12Q1/001 ,  C12Q1/006 ,  G01N33/66 ,  G01N33/728

    摘要： The present invention provides a method of measuring a component in blood, by which an amount of the component can be corrected accurately by measuring a hematocrit (Hct) value of the blood with high accuracy and high reliability and also provides a sensor used in the method. The sensor for measuring a component in blood has a first analysis portion and a second analysis portion. The first analysis portion has a first electrode system (11,12) and a reagent layer (14), and the reagent layer (14) has an oxidoreductase that acts on the component and a mediator. In the first analysis portion, the component in the blood is measured by causing a redox reaction of the component with the oxidoreductase in the presence of the mediator and detecting a redox current caused when a voltage is applied by the first electrode (11,12). The second analysis portion has a working electrode and a counter electrode, and a mediator is provided on the counter electrode but not on the working electrode. In the second analysis portion, a Hct value of the blood is measured by supplying the blood to the electrode system, applying a voltage to cause a current to flow, and detecting a value of the current. Using this Hct value, the amount of the component is corrected.

    Blood analysis device and blood analysis system using the same
    39.
    发明授权
    Blood analysis device and blood analysis system using the same 失效
    血液分析装置和血液分析系统使用相同

    公开(公告)号：US08529472B2

    公开(公告)日：2013-09-10

    申请号：US12675994

    申请日：2008-09-04

    申请人： Keisuke Matsumura ,  Masaki Fujiwara

    发明人： Keisuke Matsumura ,  Masaki Fujiwara

    IPC分类号： A61B5/00 ,  B65D81/00

    CPC分类号： A61B5/151 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150099 ,  A61B5/150213 ,  A61B5/150358 ,  A61B5/150954 ,  A61B5/15109 ,  A61B5/15134 ,  A61B5/15138 ,  A61B5/157 ,  A61B2562/0295

    摘要： A blood analysis device wherein a carrying part blood attached thereto can be localized to thereby facilitate handling after using. When incorporating blood collected from the punctured skin, the blood is held in a skin-puncturing device or the like so that an uncontaminated holding area can be enlarged and the degree of freedom in handling can be increased. A blood analysis device which comprises a plate type device body having a blood collection port for incorporating blood and a ventilation hole formed at a certain distance apart in a face and a passage located inside for connecting the blood collection port to the ventilation hole, and a blood analysis section located within the passage for analyzing the blood having been incorporated via the blood collection port.

    摘要翻译： 血液分析装置，其中附着于其上的携带部分血液可以被定位，从而便于使用后的处理。 当将从穿刺皮肤收集的血液结合时，将血液保持在皮肤穿刺装置等中，使得可以扩大未受污染的保持区域，并且可以提高处理的自由度。 一种血液分析装置，其特征在于，包括具有用于引入血液的血液采集口和在面部隔开一定距离处形成的通气孔和位于内部的用于将血液采集口连接到通气孔的板状装置体， 位于通道内的血液分析部分，用于分析通过血液采集口并入的血液。

    BIOSENSOR, THIN FILM ELECTRODE FORMING METHOD, QUANTIFICATION APPARATUS, AND QUANTIFICATION METHOD
    40.
    发明申请
    BIOSENSOR, THIN FILM ELECTRODE FORMING METHOD, QUANTIFICATION APPARATUS, AND QUANTIFICATION METHOD 有权
    生物传感器，薄膜电极形成方法，量化装置和定量方法

    公开(公告)号：US20120251708A1

    公开(公告)日：2012-10-04

    申请号：US13490553

    申请日：2012-06-07

    申请人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Masaki Fujiwara ,  Eriko Yamanishi ,  Yoshinobu Tokuno

    发明人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Masaki Fujiwara ,  Eriko Yamanishi ,  Yoshinobu Tokuno

    IPC分类号： H05K13/04 ,  B05D5/12 ,  B23K26/38 ,  C23C14/34

    CPC分类号： G01N27/3272 ,  C12Q1/001 ,  G01N33/48771 ,  Y10T29/49002

    摘要： A biosensor is disclosed comprising a support; a conductive layer composed of an electrical conductive material such as a noble metal, for example gold or palladium, and carbon; slits parallel to and perpendicular to the side of the support; working, counter, and detecting electrodes; a spacer which covers the working, counter, and detecting electrodes on the support; a rectangular cutout in the spacer forming a specimen supply path; an inlet to the specimen supply path; a reagent layer formed by applying a reagent containing an enzyme to the working, counter, and detecting electrodes, which are exposed through the cutout in the spacer; and a cover over the spacer. The biosensor can be formed by a simple method, and provides a uniform reagent layer on the electrodes regardless of the reagent composition.

    摘要翻译： 公开了一种生物传感器，其包括支撑件; 由诸如金或钯等贵金属的导电材料和碳组成的导电层; 平行于和垂直于支撑体侧面的狭缝; 工作，计数器和检测电极; 覆盖支架上的工作电极，反电极和检测电极的间隔件; 在间隔件中形成矩形切口，形成试样供应路径; 样品供应路径的入口; 通过将含有酶的试剂施加到通过所述间隔件中的切口暴露的所述工作，反向和检测电极而形成的试剂层; 和间隔物上的盖子。 可以通过简单的方法形成生物传感器，并且不管试剂组成如何，在电极上提供均匀的试剂层。