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    LATERALLY-ACTUATED DISPENSER WITH ONE-WAY VALVE FOR STORING AND DISPENSING SUBSTANCES
    31.
    发明申请
    LATERALLY-ACTUATED DISPENSER WITH ONE-WAY VALVE FOR STORING AND DISPENSING SUBSTANCES 有权
    带单向阀的侧向驱动分配器用于储存和分配物质

    公开(公告)号：US20120219348A1

    公开(公告)日：2012-08-30

    申请号：US13219597

    申请日：2011-08-26

    Applicant: Daniel Py ,  Julian Chan ,  David Fellows ,  Eric E. Hartman ,  Bing He

    Inventor： Daniel Py ,  Julian Chan ,  David Fellows ,  Eric E. Hartman ,  Bing He

    IPC: A45D40/00 ,  B65D47/20 ,  B05C17/01

    CPC classification number: B65D83/0094 ,  A45D34/04 ,  A45D2200/055 ,  A45D2200/056 ,  A61M35/003 ,  B05B11/00416 ,  B05B11/3015 ,  B05B11/3032 ,  B05B11/3033 ,  B05B11/3094 ,  B65B1/04 ,  B65D83/0033 ,  G01F11/025 ,  G01F11/08

    Abstract: A dispenser for dispensing a substance has a variable-volume storage chamber for storing the product. A dispensing portion is coupled in fluid communication with the storage chamber for receiving substance therefrom, and an outlet aperture coupled in fluid communication with the bore. A one-way valve includes a valve seat and a flexible valve cover seated on the valve seat and defining a normally-closed fluid-tight seal between the valve cover and valve seat. The flexible valve cover is movable relative to the valve seat to allow the passage of substance out of the dispenser. The dispenser further comprises a manually-engageable actuator for moving between first and second positions to dispense substance through the outlet aperture, and an integral, dome-shaped spring for biasing in a direction from one of the first and second positions toward the other.

    Abstract translation: 用于分配物质的分配器具有用于存储产品的可变容积的存储室。 分配部分与储存室流体连通地连接以接收物质，以及与孔流体连通的出口孔。 单向阀包括阀座和位于阀座上的柔性阀盖，并且在阀盖和阀座之间限定常闭流体密封。 柔性阀盖可相对于阀座移动以允许物质从分配器中通过。 分配器还包括可手动接合的致动器，用于在第一和第二位置之间移动以通过出口孔分配物质，以及一体的圆顶形弹簧，用于沿着从第一位置和第二位置之一向另一个方向偏压。

    Laterally-actuated dispenser with one-way valve for storing and dispensing metered amounts of substances
    32.
    发明授权
    Laterally-actuated dispenser with one-way valve for storing and dispensing metered amounts of substances 有权
    具有用于存储和分配计量的物质的单向阀的侧向致动的分配器

    公开(公告)号：US07665923B2

    公开(公告)日：2010-02-23

    申请号：US11237599

    申请日：2005-09-27

    Applicant: Daniel Py ,  Julian Chan ,  David Fellows ,  Eric E. Hartman ,  Bing He

    Inventor： Daniel Py ,  Julian Chan ,  David Fellows ,  Eric E. Hartman ,  Bing He

    IPC: A46B11/02

    CPC classification number: B65D83/0094 ,  A45D34/04 ,  A45D2200/055 ,  A45D2200/056 ,  A61M35/003 ,  B05B11/00416 ,  B05B11/3015 ,  B05B11/3032 ,  B05B11/3033 ,  B05B11/3094 ,  B65B1/04 ,  B65D83/0033 ,  G01F11/025 ,  G01F11/08

    Abstract: A dispenser comprising a body defining a variable-volume storage chamber and a dispensing portion defining a bore coupled in fluid communication with the storage chamber, an outlet aperture coupled in fluid communication with the bore, and a one-way valve. The valve includes an axially-extending valve seat and flexible valve cover seated on the valve seat, defining a normally-closed, axially-extending seam therebetween forming a fluid-tight seal. The valve cover is movable relative to the valve seat and the seam is connectable in fluid communication with the outlet aperture. The dispenser further comprises an actuator and piston assembly including a piston receivable within the bore, a manually-engageable actuator connected to the piston for moving the piston between first and second positions relative to the bore to dispense substance within the bore through the outlet aperture and out of the dispenser.

    Abstract translation: 一种分配器，包括限定可变容积存储室的主体和限定与存储室流体连通的孔的分配部分，与孔流体连通的出口孔和单向阀。 该阀包括位于阀座上的轴向延伸的阀座和柔性阀盖，在其间限定一个常闭的轴向延伸的接缝，形成流体密封。 阀盖可相对于阀座移动，并且接缝可与出口孔流体连通。 所述分配器还包括致动器和活塞组件，所述致动器和活塞组件包括可接收在所述孔内的活塞，连接到所述活塞的可手动接合的致动器，用于相对于所述孔在第一和第二位置之间移动所述活塞，以通过所述出口孔分配所述孔内的物质， 从分配器出来。

    LIQUID NUTRITION PRODUCT DISPENSER WITH PLURAL PRODUCT CHAMBERS FOR SEPARATE STORAGE AND INTERMIXING PRIOR TO USE, AND RELATED METHOD
    33.
    发明申请
    LIQUID NUTRITION PRODUCT DISPENSER WITH PLURAL PRODUCT CHAMBERS FOR SEPARATE STORAGE AND INTERMIXING PRIOR TO USE, AND RELATED METHOD 失效
    液体营养产品分配器，具有单独存储和使用之前的独立存储和相关方法的相关方法

    公开(公告)号：US20090139883A1

    公开(公告)日：2009-06-04

    申请号：US12259284

    申请日：2008-10-27

    Applicant: Daniel Py ,  Julian Chan ,  Jeffrey Willey

    Inventor： Daniel Py ,  Julian Chan ,  Jeffrey Willey

    IPC: B65D25/08 ,  B65B3/04

    CPC classification number: B65D47/36 ,  A61J1/202 ,  A61J9/00 ,  A61J9/008 ,  A61J11/04 ,  B65B3/04 ,  B65D47/063 ,  B65D47/265 ,  B65D47/32 ,  B65D51/002

    Abstract: A container including a body defining an outflow opening and at least one chamber adapted for storing a product, such as a fat containing liquid product, and a container closure including a primary seal for hermetically sealing the product within the chamber during storage. The container closure includes a sealing member forming a substantially fluid-tight seal between the container closure and the body, and a dispensing member in fluid communication with the chamber. The container closure and body move relative to each other between a first position where the primary seal is seated about the outflow port to hermetically seal the product in the chamber during storage, and a second position where the primary seal is displaced from the outflow port to allow product to pass from the chamber through the outflow port and into dispensing member to dispense the product.

    Abstract translation: 一种容器，其包括限定流出开口的主体和适于储存产品（例如含脂肪的液体产品）的至少一个室，以及包含用于在储存期间气密地密封室内的产品的主密封件的容器盖。 容器封闭件包括在容器封闭件和主体之间形成基本上流体密封的密封件和与腔室流体连通的分配构件的密封构件。 容器封闭件和主体在第一位置和第二位置之间移动，第一位置和第二位置之间，第一位置处主要密封件围绕流出端口安置，以便在存储期间将产品气密地密封在腔室中;以及第二位置，其中主密封件从流出端口移位到 允许产品从腔室通过流出口并进入分配构件以分配产品。

    Laterally-actuated dispenser with one-way valve for storing and dispensing metered amounts of substances
    34.
    发明申请
    Laterally-actuated dispenser with one-way valve for storing and dispensing metered amounts of substances 有权
    具有用于存储和分配计量的物质的单向阀的侧向致动的分配器

    公开(公告)号：US20060065677A1

    公开(公告)日：2006-03-30

    申请号：US11237599

    申请日：2005-09-27

    Applicant: Daniel Py ,  Julian Chan ,  David Fellows ,  Eric Hartman ,  Bing He

    Inventor： Daniel Py ,  Julian Chan ,  David Fellows ,  Eric Hartman ,  Bing He

    IPC: B67D5/40

    CPC classification number: B65D83/0094 ,  A45D34/04 ,  A45D2200/055 ,  A45D2200/056 ,  A61M35/003 ,  B05B11/00416 ,  B05B11/3015 ,  B05B11/3032 ,  B05B11/3033 ,  B05B11/3094 ,  B65B1/04 ,  B65D83/0033 ,  G01F11/025 ,  G01F11/08

    Abstract: A dispenser for dispensing a substance, such as a pharmaceutical, ophthalmic, dermatological, cosmeceutical, cosmetic or other product, has a body defining a variable-volume storage chamber for storing the product. A dispensing portion of the dispenser is connected with the body and defines a bore coupled in fluid communication with the storage chamber for receiving substance therefrom, and an outlet aperture coupled in fluid communication with the bore. A one-way valve of the dispenser includes an axially-extending valve seat and an axially-extending flexible valve cover seated on the valve seat and defining a normally-closed, axially-extending seam therebetween forming a fluid-tight seal between the valve cover and valve seat. The flexible valve cover is movable relative to the valve seat and the seam is connectable in fluid communication with the outlet aperture to allow the passage of substance through the seam and out of the dispenser. The dispenser further comprises an actuator and piston assembly including a piston receivable within the bore, a manually-engageable actuator connected to the piston for moving the piston between first and second positions relative to the bore to dispense substance within the bore through the outlet aperture, and an integral, dome-shaped spring coupled to at least one of the piston and the actuator for biasing the piston in a direction from one of the first and second positions toward the other.

    Abstract translation: 用于分配物质（例如药物，眼科，皮肤病学，药妆，化妆品或其他产品）的分配器具有限定用于存储产品的可变容积储存室的主体。 分配器的分配部分与主体连接并且限定了与储存室流体连通以接收物质的孔以及与孔流体连通的出口孔。 分配器的单向阀包括轴向延伸的阀座和位于阀座上的轴向延伸的柔性阀盖，并且在其间限定一个常闭的轴向延伸的接缝，形成在阀盖之间的流体密封 和阀座。 柔性阀盖可相对于阀座移动，并且接缝可与出口孔流体连通以允许物质通过接缝并从分配器中通过。 分配器还包括致动器和活塞组件，其包括可接收在孔内的活塞，连接到活塞的可手动接合的致动器，用于相对于孔移动活塞在第一和第二位置之间，以通过出口孔分配孔内的物质， 以及联接到所述活塞和所述致动器中的至少一个的整体的圆顶形弹簧，用于沿从所述第一位置和所述第二位置之一向另一个方向偏压所述活塞。

    Delivery device and method of delivery
    36.
    发明申请
    Delivery device and method of delivery 失效
    送货装置和送货方式

    公开(公告)号：US20050165368A1

    公开(公告)日：2005-07-28

    申请号：US10990164

    申请日：2004-11-15

    Applicant: Daniel Py ,  Julian Chan ,  Jeffrey Atwood

    Inventor： Daniel Py ,  Julian Chan ,  Jeffrey Atwood

    IPC: A61F20060101 ,  A61F9/00 ,  A61M35/00

    CPC classification number: B05B11/007 ,  A61F9/0008 ,  A61M11/007 ,  A61M15/08 ,  A61M35/003 ,  A61M2210/0612 ,  B05B11/00412 ,  B05B11/00416 ,  B05B11/0056 ,  B05B11/0072 ,  B05B11/3004 ,  B05B11/3056 ,  B05B11/307 ,  B05B11/3074 ,  B05B11/3077

    Abstract: An ophthalmic delivery device includes a body defining a fluid reservoir and a pump in fluid communication with the reservoir. The delivery device also includes a nozzle that includes a dosage chamber for holding a dosage of fluid, a valve seat, and a valve cover. The valve cover extends about the valve seat and forms an interface therebetween and the valve seat includes an outlet aperture. The interface is in fluid communication with the outlet aperture and the dosage chamber, and at least part of the valve cover is movable between (i) a closed position with the valve cover engaging the valve seat to close the interface and form a fluid-tight seal therebetween, and (ii) an open position with at least part of the valve cover spaced away from the valve seat in response to fluid flowing through the outlet aperture at a pressure greater than a valve opening pressure to allow the passage of pressurized fluid therebetween. The valve seat and the valve cover are dimensioned to dispense the dosage of fluid through the interface at a velocity of equal to or less than 6 meters per second.

    Abstract translation: 眼科输送装置包括限定流体储存器的主体和与储存器流体连通的泵。 输送装置还包括喷嘴，该喷嘴包括用于保持一定量的流体的剂量室，阀座和阀盖。 阀盖围绕阀座延伸并且在它们之间形成界面，并且阀座包括出口孔。 所述界面与所述出口孔和所述剂量室流体连通，并且所述阀盖的至少一部分可在（i）与所述阀盖接合所述阀座的关闭位置之间移动以关闭所述界面并形成流体密封 密封在其间，和（ii）打开位置，其中阀盖的至少一部分响应于流体以大于阀打开压力的压力流过出口孔而与阀座间隔开，以允许加压流体在其间通过 。 阀座和阀盖的尺寸设计为以等于或小于6米/秒的速度通过界面分配流体的剂量。

    Single use connectors
    37.
    发明授权
    Single use connectors 有权

    公开(公告)号：US10426701B2

    公开(公告)日：2019-10-01

    申请号：US15410762

    申请日：2017-01-19

    Applicant: Daniel Py

    Inventor： Daniel Py

    IPC: A61J1/20 ,  A61M5/162 ,  A61M39/10 ,  A61M39/18 ,  A61M39/26

    Abstract: Connector assembly including a piercing member having a flow port therein attached to a first piece, with the piercing member slidingly receivable within a second piece, wherein the piercing member and the second pierce are movable relative to each other between a first position where the second pieces closes the flow port and a second position where the flow port is open. The first piece contains a locking mechanism that lockingly engages with a device when connected thereto, preventing subsequent disconnection of first piece and the device. Upon initial connection of the first piece to the device, the second piece is moved from the first position to the second position.

    Device with closure, one-way valve, and storage chamber and related method
    38.
    发明授权
    Device with closure, one-way valve, and storage chamber and related method 有权

    公开(公告)号：US09737435B2

    公开(公告)日：2017-08-22

    申请号：US13745721

    申请日：2013-01-18

    Applicant: Daniel Py

    Inventor： Daniel Py

    IPC: A61F9/00 ,  B23P15/00 ,  B05B11/00 ,  B65D83/00

    CPC classification number: A61F9/0008 ,  B05B11/0056 ,  B05B11/0062 ,  B05B11/0067 ,  B05B11/007 ,  B05B11/0097 ,  B23P15/001 ,  B65D83/0022 ,  Y10T29/49412

    Abstract: A device has a first part with a valve seat and storage chamber, and a second part with a flexible valve cover and actuator. The storage chamber may be formed from a pre-form blow-molded into a flexible pouch defining a variable-volume storage chamber. The flexible valve cover and valve seat form a normally closed valve seam therebetween. The valve cover is movable in response to fluid at an inlet to the seam exceeding a valve opening pressure of the one-way valve between (i) a normally closed position with valve cover and valve seat in contact with each other and defining the normally closed seam, and (ii) a second position with at least a portion of the valve cover spaced away from the valve seat to allow the fluid to pass through the seam. The one-way valve may have anti-spritz features for using the device to dispense a substance, such as to the eye. The device may contain prostaglandins without the device material absorbing the prostaglandins material and/or without the material being adsorbed into the drug.

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