摘要:
Azole-fused peptides useful as Substance P antagonists and analgesics, for example ##STR1## wherein ##STR2## represents ##STR3## wherein X is O, S or NH and * is D, or as intermediates therefor are prepared by azole and peptide forming methods.
摘要:
A digital system includes a spur calculator that computes harmonics of a frequency of a digital clock signal and that identities a harmonic that lies in a frequency band of operation of a radio frequency circuit. A duty cycle computation module receives the harmonic and computes a duty cycle for the harmonic. Further, a clock generator that is coupled to the duty cycle computation block generates a digital clock signal of the frequency and with the duty cycle such that amplitude of spur caused due to the harmonic is suppressed.
摘要:
Disclosed are methods for the prevention or treatment of tuberculosis in a subject infected with Mycobacterium tuberculosis by administering rhodanine derivatives of formula (I), as well as some novel such compounds. Other embodiments are also disclosed.
摘要:
The present invention relates to a genus of biaryl compounds containing at least one further ring. The compounds are PDE4 inhibitors useful for the treatment and prevention of stroke, myocardial infarct and cardiovascular inflammatory diseases and disorders. The compounds have general formula I: A particular embodiment is
摘要:
A static or non-moving part electric power generator achieved by a changing (fluctuating) magnetic field (flux) by passing a pulsating direct current (DC) through a coil of wire wound on either a magnet or any material capable of producing a magnetic field, which in turn induces an alternating current (AC) in an adjacent secondary coil winding, and wherein a portion of the AC produced is used in recharging a DC source.
摘要:
Disclosed are methods for the prevention or treatment of tuberculosis in a subject infected with Mycobacterium tuberculosis by administering rhodanine derivatives of formula (I), as well as some novel such compounds. Other embodiments are also disclosed.
摘要:
The present invention relates to a chemical genus of biaryl nitrogen-attached heterocycles that are inhibitors of LTA4H (leukotriene A4 hydrolase). The compounds have the general formula They are useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders.
摘要:
The present invention provides compounds having formula (I) or (II): and pharmaceutically acceptable derivatives thereof, wherein m, p, R1, R2, R3 and R4 are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of diseases, disorders or conditions associated with HGF/SF or other cytokine activity.
摘要:
The present invention relates to a genus of biaryl compounds containing at least one further ring. The compounds are PDE4 inhibitors useful for the treatment and prevention of stroke, myocardial infarct and cardiovascular inflammatory diseases and disorders. The compounds have general formula Ia, Ib, Ic or Id: A particular embodiment is
摘要:
Compounds of the formula: are disclosed. The compounds act as phosphodiesterase-4 modulators, and useful for treating stroke, myocardial infarct, and cardiovascular inflammatory conditions. Other embodiments are also disclosed.