-
1.发明授权Cyclic carboxylic acid rhodanine derivatives for the treatment and prevention of tuberculosis 有权环状羧酸罗丹明衍生物用于治疗和预防结核病公开(公告)号：US08338465B2
公开(公告)日：2012-12-25
申请号：US12303896
申请日：2007-06-08
申请人： Jasbir Singh , Carl F. Nathan , Ruslana Bryk , Raghu Samy , Krzysztof Pupek , Mark Gurney
发明人： Jasbir Singh , Carl F. Nathan , Ruslana Bryk , Raghu Samy , Krzysztof Pupek , Mark Gurney
IPC分类号： A61K31/425 , C07D277/00
CPC分类号： C07D417/06
摘要： Disclosed are methods for the prevention or treatment of tuberculosis in a subject infected with Mycobacterium tuberculosis by administering rhodanine derivatives of formula (I), as well as some novel such compounds. Other embodiments are also disclosed.
摘要翻译： 公开了通过施用式（I）的绕丹宁衍生物以及一些新的这种化合物来预防或治疗感染结核分枝杆菌的受试者的结核病的方法。 还公开了其他实施例。
-
2.发明申请CYCLIC CARBOXYLIC ACID RHODANINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF TUBERCULOSIS 有权用于治疗和预防结核病的循环羧酸羟脯氨酸衍生物公开(公告)号：US20100210577A1
公开(公告)日：2010-08-19
申请号：US12303896
申请日：2007-06-08
申请人： Jasbir Singh , Carl F. Nathan , Ruslana Bryk , Raghu Samy , Krzysztof Pupek , Mark Gurney
发明人： Jasbir Singh , Carl F. Nathan , Ruslana Bryk , Raghu Samy , Krzysztof Pupek , Mark Gurney
IPC分类号： A61K31/427 , C07D417/06 , A61K31/4439 , C07D417/14 , A61K31/5377 , C07D277/36 , A61K31/426 , A61K31/506 , A61K31/4709 , A61K31/7036 , A61K31/496 , A61K31/4965 , A61K31/4409 , A61P31/04 , A61P31/06 , C12N9/99
CPC分类号： C07D417/06
摘要： Disclosed are methods for the prevention or treatment of tuberculosis in a subject infected with Mycobacterium tuberculosis by administering rhodanine derivatives of formula (I), as well as some novel such compounds. Other embodiments are also disclosed.
摘要翻译： 公开了通过施用式（I）的绕丹宁衍生物以及一些新的这种化合物来预防或治疗感染结核分枝杆菌的受试者的结核病的方法。 还公开了其他实施例。
-
3.发明授权Biaryl substituted heterocycle inhibitors of LTA4H for treating inflammation 失效用于治疗炎症的LTA4H的二芳基取代的杂环抑制剂公开(公告)号：US08598359B2
公开(公告)日：2013-12-03
申请号：US12136874
申请日：2008-06-11
申请人： Vincent Sandanayaka , Jasbir Singh , Mark Gurney , Bjorn Mamat , Peng Yu , Louis Bedell , Lei Zhao , Rama K. Mishra
发明人： Vincent Sandanayaka , Jasbir Singh , Mark Gurney , Bjorn Mamat , Peng Yu , Louis Bedell , Lei Zhao , Rama K. Mishra
IPC分类号： C07D211/20 , A61K31/445
CPC分类号： C07D403/12 , C07D207/08 , C07D207/09 , C07D207/12 , C07D207/26 , C07D207/263 , C07D207/46 , C07D211/22 , C07D241/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/12 , C07D409/12 , C07D413/06 , C07D413/12 , C07D417/12
摘要： The present invention relates to a chemical genus of biaryl substituted heterocycle inhibitors of LTA4H (leukotriene A4 hydrolase) useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders. The compounds have general formula Ψ: An example is
摘要翻译： 本发明涉及可用于治疗和预防和预防炎性疾病和病症的LTA4H（白三烯A4水解酶）的联芳基取代的杂环抑制剂的化学属。 化合物具有通式Psi：一个例子
-
公开(公告)号：US20090042900A1
公开(公告)日：2009-02-12
申请号：US11832255
申请日：2007-08-01
申请人： Jasbir Singh , Mark Gurney
发明人： Jasbir Singh , Mark Gurney
IPC分类号： A61K31/517 , A61P19/00 , C07D239/84 , C07D401/14
CPC分类号： C07D239/95 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14
摘要： 2,4-Diaminoquinazolines of formula (I) are provided herein and are useful for treating spinal muscular atrophy (SMA).
摘要翻译： 本文提供式（I）的2,4-二氨基喹唑啉，可用于治疗脊髓性肌萎缩（SMA）。
-
5.发明申请BIARYL SUBSTITUTED HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION 失效LTA4H用于治疗炎症的BIARYL取代的杂合物抑制剂公开(公告)号：US20090163462A1
公开(公告)日：2009-06-25
申请号：US12136874
申请日：2008-06-11
申请人： Vincent SANDANAYAKA , Jasbir Singh , Mark Gurney , Bjorn Mamat , Peng Yu , Louis Bedell , Lei Zhao , Rama K. Mishra
发明人： Vincent SANDANAYAKA , Jasbir Singh , Mark Gurney , Bjorn Mamat , Peng Yu , Louis Bedell , Lei Zhao , Rama K. Mishra
IPC分类号： A61K31/40 , C07D207/04 , C07D207/16 , C07D401/06 , A61K31/44 , A61K31/454 , A61K31/5377 , A61P29/00 , A61K31/397 , A61K31/495 , A61K31/445 , C07D211/06 , C07D241/04 , C07D413/12
CPC分类号： C07D403/12 , C07D207/08 , C07D207/09 , C07D207/12 , C07D207/26 , C07D207/263 , C07D207/46 , C07D211/22 , C07D241/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/12 , C07D409/12 , C07D413/06 , C07D413/12 , C07D417/12
摘要： The present invention relates to a chemical genus of biaryl substituted heterocycle inhibitors of LTA4H (leukotriene A4 hydrolase) useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders. The compounds have general formula Ψ: An example is
摘要翻译： 本发明涉及可用于治疗和预防和预防炎性疾病和病症的LTA4H（白三烯A4水解酶）的联芳基取代的杂环抑制剂的化学属。 化合物具有通式Psi：一个例子
-
6.发明申请ARYL SULFONAMIDE PERI-SUBSTITUTED BICYCLICS FOR OCCLUSIVE ARTERY DISEASE 审中-公开ARYL SULFONAMIDE PERI-取代的BICYCLICS FOR OCCLUSIVE ARTERY DISEASE公开(公告)号：US20090075985A1
公开(公告)日：2009-03-19
申请号：US12264053
申请日：2008-11-03
申请人： Jasbir Singh , Mark Gurney , Georgeta Hategan
发明人： Jasbir Singh , Mark Gurney , Georgeta Hategan
IPC分类号： A61K31/4245 , C07D409/14 , C07D409/12 , C07D413/14 , A61K31/4155 , A61P29/00 , A61P9/00 , A61K31/519 , A61K31/366 , A61K31/5415 , A61K31/444 , A61K31/415 , A61K31/365 , A61K31/4418 , A61K31/40 , A61K31/505 , A61K31/4365 , A61K31/445 , A61P25/00 , A61K31/404 , C07D401/02 , C07D209/04 , A61K31/47
CPC分类号： C07D209/08 , C07D409/12 , C07D409/14 , C07D413/04 , C07D413/14
摘要： Aryl sulfonamide, peri-substituted, fused bicyclic ring compounds useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed. The compounds are of the general formula A representative example is:
摘要翻译： 公开了用于治疗或预防前列腺素介导的疾病或病症的芳基磺酰胺，邻位取代的稠合双环化合物。 化合物具有通式A的代表性实例是：
-
7.发明授权Biaryl substituted heterocycle inhibitors of LTA4H for treating inflammation 失效用于治疗炎症的LTA4H的二芳基取代的杂环抑制剂公开(公告)号：US07402684B2
公开(公告)日：2008-07-22
申请号：US11426287
申请日：2006-06-23
申请人： Vincent Sandanayaka , Jasbir Singh , Mark Gurney , Bjorn Mamat , Peng Yu , Louis Bedell , Lei Zhao , Rama K. Mishra
发明人： Vincent Sandanayaka , Jasbir Singh , Mark Gurney , Bjorn Mamat , Peng Yu , Louis Bedell , Lei Zhao , Rama K. Mishra
IPC分类号： C07D207/08 , A61K31/40
CPC分类号： C07D403/12 , C07D207/08 , C07D207/09 , C07D207/12 , C07D207/26 , C07D207/263 , C07D207/46 , C07D211/22 , C07D241/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/12 , C07D409/12 , C07D413/06 , C07D413/12 , C07D417/12
摘要： The present invention relates to a chemical genus of biaryl substituted heterocycle inhibitors of LTA4H (leukotriene A4 hydrolase) useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders. The compounds have general formula Ψ: An example is
摘要翻译： 本发明涉及可用于治疗和预防和预防炎性疾病和病症的LTA4H（白三烯A4水解酶）的联芳基取代的杂环抑制剂的化学属。 化合物具有通式Psi：一个例子
-
公开(公告)号：US20070078263A1
公开(公告)日：2007-04-05
申请号：US11426284
申请日：2006-06-23
申请人： Vincent Sandanayaka , Jasbir Singh , Mark Gurney , Bjorn Mamat , Peng Yu , Louis Bedell , Lei Zhao
发明人： Vincent Sandanayaka , Jasbir Singh , Mark Gurney , Bjorn Mamat , Peng Yu , Louis Bedell , Lei Zhao
IPC分类号： C07D417/02 , C07D413/02 , C07D403/02
CPC分类号： C07D403/12 , C07D207/08 , C07D207/09 , C07D207/12 , C07D207/26 , C07D207/263 , C07D207/46 , C07D211/22 , C07D241/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/12 , C07D409/12 , C07D413/06 , C07D413/12 , C07D417/12
摘要： The present invention relates to a chemical genus of biaryl substituted heterocycle inhibitors of LTA4H (leukotriene A4 hydrolase) useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders. The compounds have general formula Ψ: An example is
-
9.发明申请Aryl sulfonamide peri-substituted bicyclics for occlusive artery disease 审中-公开用于闭塞性动脉疾病的芳酰磺酰胺四取代双环体公开(公告)号：US20060142348A1
公开(公告)日：2006-06-29
申请号：US11247456
申请日：2005-10-11
申请人： Jasbir Singh , Mark Gurney , Georgeta Hategan
发明人： Jasbir Singh , Mark Gurney , Georgeta Hategan
IPC分类号： C07D513/02 , A61K31/519 , A61K31/43 , A61K31/4188 , A61K31/4162 , A61K31/401 , A61K31/366
CPC分类号： C07D209/08 , C07D409/12 , C07D409/14 , C07D413/04 , C07D413/14
摘要： Aryl sulfonamide, peri-substituted, fused bicyclic ring compounds useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed. The compounds are of the general formula A representative example is:
摘要翻译： 公开了用于治疗或预防前列腺素介导的疾病或病症的芳基磺酰胺，邻位取代的稠合双环化合物。 化合物具有通式A的代表性实例是：
-
公开(公告)号：US20060079520A1
公开(公告)日：2006-04-13
申请号：US11169161
申请日：2005-06-27
申请人： Jasbir Singh , Mark Gurney , Georgeta Hategan , Peng Yu , David Zembower , Nian Zhou
发明人： Jasbir Singh , Mark Gurney , Georgeta Hategan , Peng Yu , David Zembower , Nian Zhou
IPC分类号： A61K31/538 , A61K31/4704 , A61K31/43 , A61K31/4188 , A61K31/4162 , C07D498/04 , C07D487/04
CPC分类号： C07D263/58 , C07D209/12 , C07D209/30 , C07D209/34 , C07D401/12 , C07D409/12 , C07D409/14 , C07D413/12 , C07D471/04 , C07D487/04 , C07D513/04
摘要： Acyl sulfonamide, peri-substituted, fused bicyclic ring compounds useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed. The compounds are of the general formula A representative example is:
-
-
-
-
-
-
-
-
-
搜索结果
87 条记录 (耗时 0.059 秒)
