公开(公告)号：US12048540B2

公开(公告)日：2024-07-30

申请号：US16261339

申请日：2019-01-29

Applicant: DexCom, Inc.

Inventor： Stephen J. Vanslyke ,  Naresh C. Bhavaraju ,  Sebastian Böhm ,  Leif N. Bowman ,  Michael J. Estes ,  Arturo Garcia ,  Apurv Ullas Kamath ,  Andrew Attila Pal ,  Thomas A. Peyser ,  Anna Leigh Davis ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Dmytro Sokolovsky

IPC: A61B5/1495 ,  A61B5/00 ,  A61B5/01 ,  A61B5/053 ,  A61B5/11 ,  A61B5/145 ,  A61B5/1473 ,  A61B5/1486 ,  A61M5/172 ,  G16Z99/00

CPC classification number: A61B5/1495 ,  A61B5/01 ,  A61B5/053 ,  A61B5/1118 ,  A61B5/14532 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/4833 ,  A61B5/4839 ,  A61B5/4848 ,  A61B5/4866 ,  A61B5/6898 ,  A61B5/7203 ,  A61B5/7221 ,  A61B5/7275 ,  A61B5/7278 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/746 ,  A61M5/1723 ,  G16Z99/00 ,  A61B2560/0247 ,  A61B2560/0252 ,  A61B2560/0276 ,  A61B2560/0475 ,  A61B2562/0247 ,  A61M2205/3584 ,  A61M2205/3592 ,  A61M2205/50 ,  A61M2205/52 ,  A61M2230/201

Abstract: Systems and methods disclosed here provide ways to discriminate fault types encountered in analyte sensors and systems and further provide ways to process such discriminated faults responsively based on sensor data, clinical context information, and other data about the patient or patient's environment. The systems and methods thus employ clinical context in detecting and/or responding to errors or faults associated with an analyte sensor system, and discriminating the type of fault, and its root cause, particularly as fault dynamics can appear similar to the dynamics of physiological systems, emphasizing the importance of discriminating the fault and providing appropriate responsive processing. Thus, the disclosed systems and methods consider the context of the patient's health condition or state in determining how to respond to the fault.

公开(公告)号：US12011265B2

公开(公告)日：2024-06-18

申请号：US16359765

申请日：2019-03-20

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Jennifer Blackwell ,  Sebastian Böhm

IPC: H01S4/00 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1473 ,  A61B5/1486 ,  A61B17/34 ,  A61B17/00 ,  A61L31/08 ,  B21G1/00 ,  B21G1/12

CPC classification number: A61B5/1473 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/14865 ,  A61B5/4839 ,  A61B5/6848 ,  A61B17/3468 ,  A61B2017/00004 ,  A61B2562/12 ,  A61L31/08 ,  B21G1/003 ,  B21G1/006 ,  B21G1/12 ,  Y10T29/49002

Abstract: Sensor devices including dissolvable tissue-piercing tips are provided. The sensor devices can be used in conjunction with dissolvable needles configured for inserting the sensor devices into a host. Hardening agents for strengthening membranes on sensor devices are also provided. Methods of using and fabricating sensor devices are also provided.

公开(公告)号：US11484232B2

公开(公告)日：2022-11-01

申请号：US16254080

申请日：2019-01-22

Applicant: DexCom, Inc.

Inventor： Anna Claire Harley-Trochimczyk ,  Sebastian Böhm ,  Rui Ma ,  Disha B. Sheth ,  Minglian Shi ,  Kamuran Turksoy

IPC: A61B5/00 ,  A61B5/1495 ,  A61B5/0205 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/01 ,  G16H50/20 ,  G01N27/327 ,  A61B5/024 ,  A61B5/11

Abstract: This document discusses, among other things, systems and methods to compensate for the effects of temperature on sensors, such as analyte sensor. An example method may include determining a temperature-compensated glucose concentration level by receiving a temperature signal indicative of a temperature parameter of an external component, receiving a glucose signal indicative of an in vivo glucose concentration level, and determining a compensated glucose concentration level based on the glucose signal, the temperature signal, and a delay parameter.

公开(公告)号：US20210369149A1

公开(公告)日：2021-12-02

申请号：US17398628

申请日：2021-08-10

Applicant: DexCom, Inc.

Inventor： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC: A61B5/1495 ,  G01N27/327 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/00 ,  G01D18/00 ,  G01N27/02 ,  G01N33/49 ,  A61B5/1473

Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US20210076989A1

公开(公告)日：2021-03-18

申请号：US16951596

申请日：2020-11-18

Applicant: DexCom, Inc.

Inventor： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC: A61B5/1495 ,  G01N27/327 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/00 ,  G01D18/00 ,  G01N27/02 ,  G01N33/49 ,  A61B5/1473

Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US10722162B2

公开(公告)日：2020-07-28

申请号：US16586407

申请日：2019-09-27

Applicant: DexCom, Inc.

Inventor： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC: G08B21/20 ,  A61B5/1495 ,  G01N27/327 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/00 ,  G01D18/00 ,  G01N27/02 ,  G01N33/49 ,  A61B5/1473

Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US20190336051A1

公开(公告)日：2019-11-07

申请号：US16459158

申请日：2019-07-01

Applicant: DexCom, Inc.

Inventor： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC: A61B5/1495 ,  G01N33/49 ,  A61B5/1486 ,  A61B5/145 ,  A61B5/00 ,  A61B5/1473 ,  G01N27/02 ,  G01N27/327 ,  G01D18/00

Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US20190227022A1

公开(公告)日：2019-07-25

申请号：US16254080

申请日：2019-01-22

Applicant: DexCom, Inc.

Inventor： Anna Claire Harley-Trochimczyk ,  Sebastian Böhm ,  Rui Ma ,  Disha B. Sheth ,  Minglian Shi ,  Kamuran Turksoy

IPC: G01N27/327 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/1495

Abstract: This document discusses, among other things, systems and methods to compensate for the effects of temperature on sensors, such as analyte sensor. An example method may include determining a temperature-compensated glucose concentration level by receiving a temperature signal indicative of a temperature parameter of an external component, receiving a glucose signal indicative of an in vivo glucose concentration level, and determining a compensated glucose concentration level based on the glucose signal, the temperature signal, and a delay parameter.

公开(公告)号：US10327688B2

公开(公告)日：2019-06-25

申请号：US15994905

申请日：2018-05-31

Applicant: DexCom, Inc.

Inventor： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC: G08B21/20 ,  A61B5/1495 ,  G01N27/327 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/00 ,  G01D18/00 ,  G01N27/02 ,  G01N33/49 ,  A61B5/1473

Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US20180042530A1

公开(公告)日：2018-02-15

申请号：US15726272

申请日：2017-10-05

Applicant: DexCom, Inc.

Inventor： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC: A61B5/1495 ,  G01N27/327 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/1473 ,  G01D18/00 ,  G01N27/02 ,  G01N33/49 ,  A61B5/00

CPC classification number: A61B5/1495 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/7257 ,  A61B5/7267 ,  A61B2560/0276 ,  G01D18/00 ,  G01N27/026 ,  G01N27/3274 ,  G01N33/49 ,  H05K999/00 ,  H05K999/99

Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.