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公开(公告)号：US20220287838A1
公开(公告)日：2022-09-15
申请号：US17829769
申请日：2022-06-01
Applicant: Edwards Lifesciences Corporation
Inventor： Oren Cohen , Tomer Saar , Elazar Levi Schwarcz , Ofir Witzman , Eitan Atias , Noam Miller , Eran Goldberg , Yair A. Neumann
Abstract: A delivery apparatus for implanting a prosthetic valve includes a handle, a first shaft, a plurality of actuation shafts, and a control mechanism. The first shaft has one or more lumens extending from the first end portion to the second end portion. The actuation shafts each have a proximal end portion and a distal end portion, and the actuation shafts extend through the one or more lumens of the first shaft. The control mechanism is coupled to the actuation shafts and to the handle. The control mechanism is configured such that the actuation shafts can move axially relative to each other in a first operational mode and such that the actuation shafts can be moved axially simultaneously in a second operational mode. Additionally or alternatively, the first shaft can include a plurality of helical lumens configured for receiving the actuation shafts.
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公开(公告)号：US20220257367A1
公开(公告)日：2022-08-18
申请号：US17732985
申请日：2022-04-29
Applicant: Edwards Lifesciences Corporation
Inventor： Yair A. Neumann , Oren Cohen , Khen Perlmutter , Eitan Atias , Noam Miller , Eran Goldberg , Anatoly Dvorsky , Tamir S. Levi , Haim Yushtein , Danny M. Garmahi , Ziv Yohanan , Michael Bukin , Noam Nir , Elena Sherman , Gideon Sagi
IPC: A61F2/24
Abstract: An implantable prosthetic valve can include a frame movable between a radially compressed and a radially expanded configuration. The frame can include a first strut having a first locking feature disposed on a radially facing inner surface of the strut and a second strut having a second locking feature disposed on a radially facing outer surface of the strut. The first and second locking features can engage each other so as to allow pivoting of the first and second struts relative to one another in a first direction upon radial expansion of the frame and resist pivoting of the first and second struts relative to one another in a second direction to resist radial compression of the frame.
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公开(公告)号：US20220168125A1
公开(公告)日：2022-06-02
申请号：US17673601
申请日：2022-02-16
Applicant: Edwards Lifesciences Corporation
Inventor： Eran Goldberg , Noa Axelrod Manela , Yair A. Neumann , Boaz Manash , David Maimon , Eyal Leiba , Ralph Schneider , Liron Tayeb
Abstract: An expandable sheath is disclosed herein, which has a first polymeric layer and a braided layer positioned radially outward of the first polymeric layer. The braided layer includes a plurality of filaments braided together. The expandable sheaths further include a resilient elastic layer positioned radially outward of the braided layer. The elastic layer is configured to apply radial force to the braided layer and the first polymeric layer. The expandable sheath further includes a second polymeric layer positioned radially outward of the elastic layer and bonded to the first polymeric layer such that the braided layer and the elastic layer are encapsulated between the first and second polymeric layers. Methods of making and using the devices disclosed herein are also disclosed, as are crimping devices that may be used in methods of making the devices disclosed herein.
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公开(公告)号：US20160317305A1
公开(公告)日：2016-11-03
申请号：US15140387
申请日：2016-04-27
Applicant: Edwards Lifesciences Corporation
Inventor： Itai Pelled , Elena Sherman , Eran Goldberg , Kevin D. Rupp , Noam Nir
CPC classification number: B29C66/53245 , A61F2/2412 , A61F2/2415 , A61F2/2418 , A61F2/2433 , A61F2210/0076 , A61F2230/0069 , A61F2240/001 , A61F2250/0069
Abstract: The present disclosure relates to laminated sealing members for prosthetic valves and methods of making the same. In a representative embodiment, an implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration comprises an annular frame having an inflow end and an outflow end, a leaflet structure positioned within the frame and secured thereto, and a laminate sealing member comprising an encapsulating material. The laminate sealing member has a main portion that encapsulates at least a portion of the frame and an end portion extending from the inflow end of the frame, and the end portion of the laminate sealing member is folded to form a cuff adjacent the inflow end of the frame and secured to the main portion of the laminate sealing member.
Abstract translation: 本公开涉及用于人造瓣的层压密封构件及其制造方法。 在代表性的实施例中，可径向可折叠到收缩构造并且可径向扩张到扩张构造的可植入假体瓣包括具有流入端和流出端的环形框架，定位在框架内并固定到其上的小叶结构， 层压密封件包括封装材料。 层叠密封构件具有封闭框架的至少一部分的主要部分和从框架的流入端延伸的端部，并且层叠密封构件的端部折叠形成邻近流入端的套筒 框架并固定到层压密封件的主要部分。
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公开(公告)号：US20250161656A1
公开(公告)日：2025-05-22
申请号：US19029059
申请日：2025-01-17
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Eran Goldberg
IPC: A61M60/157 , A61M60/139 , A61M60/274 , A61M60/427 , A61M60/839 , A61M60/869
Abstract: A compliance restoration implant device includes a first compliant fluid container, a second compliant fluid container, and a conduit structure. The first compliant fluid container includes a first lumen that widens in response to fluid leaving the first compliant fluid container and narrows in response to the fluid entering the first compliant fluid container. The second compliant fluid container includes a second lumen that widens in response to the fluid leaving the second compliant fluid container and narrows in response to the fluid entering the second compliant fluid container. The conduit structure is coupled to the first compliant fluid container and the second compliant fluid container and is configured to pass fluid between the first compliant fluid container and the second compliant fluid container in response to changing pressure levels outside one of the fluid containers.
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Patent Agency Ranking
公开(公告)号：US20250143876A1
公开(公告)日：2025-05-08
申请号：US19016497
申请日：2025-01-10
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Eran Grosu , Eran Goldberg , Sean Timothy O'keeffe , Douglas Thomas Dominick , Michal Lipperman
IPC: A61F2/24
Abstract: In some examples, a medical implant includes a frame and a radiopaque marker. The radiopaque marker is coupled to the strut with a recessed surface portion of the radiopaque marker positioned in opposing relation to a first concave surface of a strut portion of the frame. In some examples, at least one strut of the frame has a bore, an eyelet, and a strut portion between the bore and the eyelet. The radiopaque marker is disposed within the bore and has an edge surface with a recessed surface portion positioned in opposing relation to a first surface of the strut portion. In some examples, a medical assembly includes a delivery apparatus, a frame, and a radiopaque marker.
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公开(公告)号：US12186184B2
公开(公告)日：2025-01-07
申请号：US17657732
申请日：2022-04-01
Applicant: Edwards Lifesciences Corporation
Inventor： Liron Tayeb , Eran Goldberg , David Maimon , Adi Carmi , Arie Tylis , Ralph Schneider , Mohammad Jafari , Hengchu Cao , Eitan Atias
Abstract: An expandable docking station includes an annular valve seat having an end, an annular outer wall comprising struts disposed around the valve seat, and links that connect the end of the annular valve seat to the annular outer wall. Each of the links extends from the struts of the annular outer wall directly toward a longitudinal axis that runs longitudinally through a center of the docking station, and to a corresponding one of a plurality of circumferentially spaced axially extending legs at least partially defining the annular valve seat. The outer wall is configured to conform to an interior shape of a blood vessel, when expanded inside the blood vessel, such that the outer wall can expand in multiple locations to conform to multiple bulges of the blood vessel and can contract in multiple locations to conform to multiple narrowed regions of the blood vessel.
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公开(公告)号：US20240358511A1
公开(公告)日：2024-10-31
申请号：US18767778
申请日：2024-07-09
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： David Maimon , Liron Tayeb , Eran Goldberg
CPC classification number: A61F2/2439 , A61F2/2427 , A61F2/2433 , A61M25/0023 , A61F2/9517 , A61M2025/0024
Abstract: The active introducer sheath systems disclosed herein are expanded by activating a translation mechanism at the handle. The sheath has an inner cylindrical structure of comingled fixed and mobile elongate rods bound together by an attachment line. Activating the translation mechanism causes the mobile rods to move axially with respect to the fixed rods, changing the internal tension in the attachment line. Increased tension draws the fixed and mobile rods closer together, decreasing the diameter of the cylindrical structure. Decreased tension in the attachment line enables the fixed and mobile rods to move apart, increasing the diameter of the cylindrical structure. A prosthetic device, such as a prosthetic heart valve, can be routed through the expanded sheath and to the implantation site. During implantation, the sheath can be contracted back to its original outer diameter, and expanded again for retrieval of the delivery apparatus.
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公开(公告)号：US12070388B2
公开(公告)日：2024-08-27
申请号：US18138651
申请日：2023-04-24
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： David Maimon , Liron Tayeb , Eran Goldberg
CPC classification number: A61F2/2439 , A61F2/2427 , A61F2/2433 , A61M25/0023 , A61F2/9517 , A61M2025/0024
Abstract: The active introducer sheath systems disclosed herein are expanded by activating a translation mechanism at the handle. The sheath has an inner cylindrical structure of comingled fixed and mobile elongate rods bound together by an attachment line. Activating the translation mechanism causes the mobile rods to move axially with respect to the fixed rods, changing the internal tension in the attachment line. Increased tension draws the fixed and mobile rods closer together, decreasing the diameter of the cylindrical structure. Decreased tension in the attachment line enables the fixed and mobile rods to move apart, increasing the diameter of the cylindrical structure. A prosthetic device, such as a prosthetic heart valve, can be routed through the expanded sheath and to the implantation site. During implantation, the sheath can be contracted back to its original outer diameter, and expanded again for retrieval of the delivery apparatus.
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公开(公告)号：US20240091004A1
公开(公告)日：2024-03-21
申请号：US18526391
申请日：2023-12-01
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Noam Nir , Michael Bukin , Eran Goldberg
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/91 , A61F2220/0091 , A61F2250/001 , A61F2250/0018
Abstract: An implantable prosthetic device can include a hybrid frame movable between a radially compressed configuration and a radially expanded configuration. The hybrid frame can include a mechanically-expandable first sub-frame comprising a plurality of struts pivotably coupled to one another, and a plastically deformable second sub-frame coupled to the first sub-frame. When the hybrid frame is in the expanded configuration, the second sub-frame can be configured to resist radial compression of the frame.
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