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    Opaque reaction matrix for the analysis of the whole blood
    31.
    发明授权
    Opaque reaction matrix for the analysis of the whole blood 失效
    不透明反应矩阵用于分析全血

    公开(公告)号：US5968765A

    公开(公告)日：1999-10-19

    申请号：US961942

    申请日：1997-10-31

    申请人： Henry M. Grage ,  Joel S. Douglas ,  Pat S. Lee

    发明人： Henry M. Grage ,  Joel S. Douglas ,  Pat S. Lee

    IPC分类号： B01D69/14 ,  C12Q1/26 ,  C12Q1/54 ,  G01N33/50 ,  G01N33/52 ,  C12Q1/00

    CPC分类号： G01N33/52 ,  B01D69/141 ,  C12Q1/26 ,  C12Q1/54 ,  G01N33/5002 ,  G01N33/521 ,  Y10S435/968 ,  Y10S435/97

    摘要： A test strip for use in determining the presence or concentration of an analyte in whole blood is disclosed. The test strip is a porous membrane having disposed thereon (a) a separating agent capable of separating from whole blood, red blood cells and a fluid component substantially free of red blood cells; (b) an indicating reagent system capable of indicating the presence or concentration of an analyte in the fluid component by producing a spectrophotometric change upon contact with the fluid component; and (c) an opaque filler capable of reducing spectrophotometric interference caused by the presence of the red blood cells. Also disclosed are methods of testing whole blood for the presence or concentration of an analyte using the test strip.

    摘要翻译： 公开了一种用于确定全血中分析物的存在或浓度的测试条。 测试条是其上设置有多孔膜（a）能够从全血，红细胞和基本上不含红细胞的流体组分分离的分离剂; （b）指示试剂系统，其能够通过在与流体组分接触时产生分光光度变化来指示流体组分中分析物的存在或浓度; 和（c）能够减少由红细胞存在引起的分光光度干扰的不透明填料。 还公开了使用测试条测试全血的分析物的存在或浓度的方法。

    METHODS AND APPARATUS FOR EXPRESSING BODY FLUID FROM AN INCISION
    32.
    发明申请
    METHODS AND APPARATUS FOR EXPRESSING BODY FLUID FROM AN INCISION 审中-公开
    用于从体内表达体液的方法和装置

    公开(公告)号：US20110046515A1

    公开(公告)日：2011-02-24

    申请号：US12938784

    申请日：2010-11-03

    申请人： Joel S. Douglas ,  Jeffrey N. Roe ,  Henry M. Grage

    发明人： Joel S. Douglas ,  Jeffrey N. Roe ,  Henry M. Grage

    IPC分类号： A61B5/151

    CPC分类号： A61B5/15194 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150076 ,  A61B5/150083 ,  A61B5/150412 ,  A61B5/150503 ,  A61B5/15111 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/1519 ,  A61B10/0045 ,  A61B2010/008 ,  A61B2017/00765 ,  A61B2562/0295

    摘要： A sample of a body fluid such as blood or interstitial fluid is obtained from a body by lancing a portion of a user's skin, preferably in an area other than a finger tip, to form an incision. After the needle has been removed from the incision, a force is applied to depress the skin in a manner forming a ring of depressed body tissue in surrounding relationship to the incision, causing the incision to bulge and the sides of the incision to open, whereby body fluid is forced out through the opening of the incision. A stimulator member is mounted to an end of a lancet-carrying housing for applying the force. The stimulator member can be movable relative to the housing, and can be either heated or vibrated to promote movement of the body fluid.

    摘要翻译： 体液例如血液或间质液的样品通过使用者的皮肤的一部分优选在指尖以外的区域穿刺而从身体获得，以形成切口。 在针从切口移除之后，施加力以形成与切口周围关系的形成凹陷的身体组织的环的方式来压下皮肤，导致切口凸起并且切口的两侧打开，由此 体液通过切口的开口被迫出来。 刺激构件安装到用于施加力的刺血针承载壳体的端部。 刺激器构件可以相对于壳体可移动，并且可以被加热或振动以促进体液的移动。

    INFUSION HUB ASSEMBLY AND FLUID LINE DISCONNECT SYSTEM
    33.
    发明申请
    INFUSION HUB ASSEMBLY AND FLUID LINE DISCONNECT SYSTEM 有权
    输液管组件和流体管线断开系统

    公开(公告)号：US20100268166A1

    公开(公告)日：2010-10-21

    申请号：US12825228

    申请日：2010-06-28

    申请人： Joel S. Douglas ,  Robert L. Hugo ,  Cynthia Zhang

    发明人： Joel S. Douglas ,  Robert L. Hugo ,  Cynthia Zhang

    IPC分类号： A61M5/158 ,  A61M5/14

    CPC分类号： A61M39/14 ,  A61M5/158 ,  A61M2005/1581 ,  A61M2005/1587 ,  A61M2039/1072

    摘要： An infusion set comprising a base and a cap. The base can comprise a portion to be placed against skin, a first cannula extending downwardly below the portion to be placed against skin, and a septum. The cap can comprise a tube and a second cannula. The cap can be configured for removable attachment to the base such that the cap is rotatable with respect to the base while the first cannula, the second cannula, and the tube are in fluid communication.

    摘要翻译： 一种输液器，包括基座和盖子。 底座可以包括一部分被放置在皮肤上的部分，第一套管向下延伸到防止皮肤放置的部分下方，以及隔膜。 盖可以包括管和第二套管。 帽可以被配置为可移除地连接到基座，使得帽可相对于基座旋转，同时第一插管，第二插管和管流体连通。

    Infusion device having offset flow path
    37.
    发明授权
    Infusion device having offset flow path 失效
    具有偏移流路的输液装置

    公开(公告)号：US06923791B2

    公开(公告)日：2005-08-02

    申请号：US10814950

    申请日：2004-03-30

    申请人： Joel S. Douglas

    发明人： Joel S. Douglas

    IPC分类号： A61M20060101 ,  A61M5/158 ,  A61M5/178 ,  A61M11/00 ,  A61M25/02 ,  A61M31/00

    CPC分类号： A61M5/158 ,  A61M25/02 ,  A61M2005/1581 ,  A61M2005/1587

    摘要： An infusion device, including: a housing; an infusion cannula extending downwardly away from the housing and capable of receiving an insertion needle; a septum disposed in the housing; a passageway under said septum and in fluid communication with said cannula; and, an infusion needle insertable through the septum, the infusion needle capable of penetrating the septum and entering said passageway thereby forming a flow path between the infusion needle and the infusion cannula and wherein the infusion cannula and the infusion needle are aligned on separate non identical axes.

    摘要翻译： 一种输液装置，包括：壳体; 输液套管，其从壳体向外延伸并能够接收插入针头; 设置在壳体中的隔膜; 在所述隔膜下方的通道并与所述套管流体连通; 以及可插入通过所述隔膜的输注针，所述输注针能够穿透所述隔膜并进入所述通道，从而在所述输注针和所述输注套管之间形成流路，并且其中所述输注套管和所述输注针在分开的不相同 轴。

    Infusion hub assembly and fluid line disconnect system
    38.
    发明授权
    Infusion hub assembly and fluid line disconnect system 有权
    输液轮毂总成和流体管路断开系统

    公开(公告)号：US06685674B2

    公开(公告)日：2004-02-03

    申请号：US10091123

    申请日：2002-03-04

    申请人： Joel S. Douglas ,  Robert L. Hugo ,  Cynthia Zhang

    发明人： Joel S. Douglas ,  Robert L. Hugo ,  Cynthia Zhang

    IPC分类号： A61M5178

    CPC分类号： A61M39/14 ,  A61M5/158 ,  A61M2005/1581 ,  A61M2005/1587 ,  A61M2039/1072

    摘要： An infusion hub assembly, comprising: a hub received in a hole in a wing, the hub having a bore passing therethrough, with an upper portion of the circular hub having an attachment surface thereon; an infusion cannula extending downwardly away from the wing, the infusion cannula being in fluid communication with the bore passing through the hub; a cover having a bore passing therethrough and having an inner attachment surface adapted to mate with the attachment surface on the upper portion of the hub; and a septum positioned in alignment with the bore passing through the cover.

    摘要翻译： 一种输液轮毂组件，包括：容纳在机翼中的孔中的毂，所述轮毂具有穿过其中的孔，所述圆形轮毂的上部在其上具有附接表面; 输液套管向下延伸离开翼部，输注套管与穿过轮毂的孔流体连通; 具有穿过其中的孔并且具有适于与轮毂的上部上的附接表面配合的内部附接表面的盖; 以及与穿过盖的孔对准定位的隔膜。

    Membrane based electrochemical test device
    39.
    发明授权
    Membrane based electrochemical test device 失效
    基于膜的电化学测试装置

    公开(公告)号：US06582573B2

    公开(公告)日：2003-06-24

    申请号：US09878774

    申请日：2001-06-08

    申请人： Joel S. Douglas ,  Jeffrey N. Roe ,  John H. Priest ,  David A. Hasker

    发明人： Joel S. Douglas ,  Jeffrey N. Roe ,  John H. Priest ,  David A. Hasker

    IPC分类号： G01N27327

    CPC分类号： C12Q1/001 ,  C12Q1/26 ,  G01N27/3272 ,  G01N33/54386

    摘要： An electrochemical test device is provided for determining the presence or concentration of an analyte in an aqueous fluid sample. The electrochemical test device includes a working electrode and a counter electrode made of an amorphous semiconductor material. The working electrode is overlaid with a reagent capable of reacting with an analyte to produce a measurable change in potential which can be correlated to the concentration of the analyte in the fluid sample. The test device optionally contains a reference electrode made of an amorphous semiconductor material having a reference material on the reference electrode.

    摘要翻译： 提供电化学测试装置，用于确定含水流体样品中分析物的存在或浓度。 电化学测试装置包括工作电极和由非晶半导体材料制成的对电极。 工作电极与能够与分析物反应的试剂重叠，以产生可测量的电位变化，其可以与流体样品中分析物的浓度相关。 测试装置可选地包含由在参考电极上具有参考材料的非晶半导体材料制成的参考电极。

    Methods and apparatus for expressing body fluid from an incision
    40.
    发明授权
    Methods and apparatus for expressing body fluid from an incision 有权
    用于从切口表达体液的方法和装置

    公开(公告)号：US06319210B1

    公开(公告)日：2001-11-20

    申请号：US09586969

    申请日：2000-06-05

    申请人： Joel S. Douglas ,  Jeffrey N. Roe ,  Henry M. Grage

    发明人： Joel S. Douglas ,  Jeffrey N. Roe ,  Henry M. Grage

    IPC分类号： A61B500

    CPC分类号： A61B5/14532 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150076 ,  A61B5/150083 ,  A61B5/150412 ,  A61B5/15109 ,  A61B5/15117 ,  A61B5/15186 ,  A61B5/15194 ,  A61B10/0045 ,  A61B2010/008 ,  A61B2017/00765 ,  A61B2562/0295

    摘要： A sample of a body fluid such as blood or interstitial fluid is obtained from a body by lancing a portion of a user's skin, preferably in an area other than a finger tip, to form an incision. After the needle has been removed from the incision, a force is applied to depress the skin in a manner forming a ring of depressed body tissue in surrounding relationship to the incision, causing the incision to bulge and the sides of the incision to open, whereby body fluid is forced out through the opening of the incision. A stimulator member is mounted to an end of a lancet-carrying housing for applying the force. The stimulator member can be movable relative to the housing, and can be either heated or vibrated to promote movement of the body fluid.

    摘要翻译： 体液例如血液或间质液的样品通过使用者的皮肤的一部分优选在指尖以外的区域穿刺而从身体获得，以形成切口。 在针从切口移除之后，施加力以形成与切口周围关系的凹陷的身体组织环的方式来压下皮肤，导致切口凸起并且切口的两侧打开，由此 体液通过切口的开口被迫出来。 刺激构件安装到用于施加力的刺血针承载壳体的端部。 刺激器构件可以相对于壳体可移动，并且可以被加热或振动以促进体液的移动。