公开(公告)号：US20230279100A1

公开(公告)日：2023-09-07

申请号：US17742375

申请日：2022-05-11

Applicant: Feng Xue

Inventor： Feng Xue

IPC: C07K16/28 ,  C12N15/113 ,  C12N9/22 ,  C12N15/11 ,  A61P25/28

CPC classification number: C07K16/28 ,  C12N15/1138 ,  C12N9/22 ,  C12N15/11 ,  A61P25/28 ,  C12N2310/141 ,  C12N2310/14 ,  C12N2310/11

Abstract: The disclosed embodiments relate the general methods for prevention or treatment of Alzheimer's Disease (AD) by blocking or decreasing STING (TMEM173) signaling activation. Our study showed that, in the young (2-3 months old) AD 5XFAD animal models, before the plaque accumulation of Aβ amyloid protein, blocking (e.g.,. gene knockout) or decreasing (e.g., small molecule antagonist treatment) Sting (Tmem173) signaling activation significantly reduced the pro-inflammatory activation and the proliferation of microglia (Mg) cells, enhanced the lysosomal synthesis and the protein antigen degradation of Mg cells, decreased the neuron loss and the AD neuroinflammation, and improved the cognitive ability of the AD 5XFAD mouse models. Therefore, in the mild AD or in the early stages of AD, blocking or decreasing STING signaling activation can be used for prevention or treatment of AD.

公开(公告)号：US09230030B2

公开(公告)日：2016-01-05

申请号：US12340935

申请日：2008-12-22

Applicant: Feng Xue ,  Abha Moitra ,  Steven Matt Gustafson

Inventor： Feng Xue ,  Abha Moitra ,  Steven Matt Gustafson

IPC: G06F15/177 ,  G06F17/30 ,  H04L29/08

CPC classification number: G06F17/30867 ,  H04L67/22

Abstract: One website mining embodiment is for characterizing first time users of a website, collecting user session data of the users visiting the website and identifying first time visitors, determining features of the first time visitors utilizing the user session data, determining rules utilizing the features of the first time visitors, monitoring actions of the first time visitors on the website, updating the rules utilizing the monitored actions of the first time visitors and recommending web content utilizing the rules to the first time visitor.

Abstract translation: 一个网站挖掘实施例用于表征网站的第一时间用户，收集访问网站的用户的用户会话数据并识别首次访问者，确定首次访问者利用用户会话数据的特征，使用所述用户会话数据的特征来确定规则 第一次访问者，首次访问网站的访问者的监控动作，使用第一次访问者的监控动作更新规则，并首次访问者使用规则推荐网页内容。

公开(公告)号：US20150189593A1

公开(公告)日：2015-07-02

申请号：US14583698

申请日：2014-12-27

Applicant: Feng Xue ,  Qinghua Li ,  Wendy C. Wong

Inventor： Feng Xue ,  Qinghua Li ,  Wendy C. Wong

IPC: H04W52/02 ,  H04W74/08 ,  H04W72/04

CPC classification number: H04W52/0216 ,  H04W52/0238 ,  H04W52/24 ,  H04W52/286 ,  H04W52/367 ,  H04W52/383 ,  H04W72/0446 ,  H04W74/002 ,  H04W74/0808 ,  Y02D70/142 ,  Y02D70/144 ,  Y02D70/146

Abstract: Embodiments may comprise logic to determine whether a value of a network allocation vector indicates that the apparatus is blocked from transmitting on the medium; logic to transmit a first clear to send packet at a first power level in response to determining that the apparatus is not blocked from transmitting on the medium, the first clear to send packet comprising a flag or bit to indicate the Shading Transmission Starts (STS); logic to receive a second clear to send packet after transmitting the first clear to send packet; and logic to transmit a first data transmission at a second power level after receiving the second clear to send packet, the second power level being less than the first power level.

Abstract translation: 实施例可以包括用于确定网络分配向量的值是否指示该设备被阻止在介质上的传输的逻辑; 响应于确定所述装置不被阻止在所述介质上的传输，以第一功率电平发送第一清除发送分组的逻辑，所述第一清除发送分组包括标志或比特以指示所述着色传输开始（STS） ; 在发送第一个清除发送包之后接收第二个清除发送包的逻辑; 以及在接收到所述第二清除发送分组之后以第二功率电平发送第一数据传输的逻辑，所述第二功率电平小于所述第一功率电平。

公开(公告)号：US20150131750A1

公开(公告)日：2015-05-14

申请号：US14126037

申请日：2013-09-05

Applicant: Feng Xue ,  Jong-Kae Fwu ,  Masoud Sajadieh ,  Qinghua Li

Inventor： Feng Xue ,  Jong-Kae Fwu ,  Masoud Sajadieh ,  Qinghua Li

IPC: H04B7/04 ,  H04W24/08 ,  H04B7/06

CPC classification number: H04B7/0482 ,  H04B7/024 ,  H04B7/0452 ,  H04B7/0456 ,  H04B7/0617 ,  H04B7/0639 ,  H04B7/0695 ,  H04W24/08

Abstract: Technology to adaptively sectorize a spatial region for parallel multi-user transmissions is disclosed. In an example, a node (e.g., evolved Node B (eNB)) can include computer circuitry configured to: Generate a set of precoding matrices for a set of beam cones in the spatial region; and generate a beam cone for multi-user beamforming transmissions using system information for the beam cone. A precoding matrix in the set of precoding matrices can be used for each beam cone, and each beam cone can cover a beam cone spatial region that differs from another beam cone spatial region of another beam cone in the spatial region. Each beam cone can include system information that differs from the system information of the other beam cones in the spatial region.

Abstract translation: 公开了用于对用于并行多用户传输的空间区域进行自适应划分的技术。 在一个示例中，节点（例如，演进节点B（eNB））可以包括被配置为：为空间区域中的一组波束锥生成一组预编码矩阵的计算机电路; 并使用束锥的系统信息生成用于多用户波束成形传输的波束锥。 预编码矩阵集合中的预编码矩阵可用于每个波束锥，并且每个波束锥可以覆盖不同于空间区域中另一波束锥的另一波束锥空间区域的波束锥空间区域。 每个束锥可以包括与空间区域中的其他束锥的系统信息不同的系统信息。

公开(公告)号：US20150049732A1

公开(公告)日：2015-02-19

申请号：US14125973

申请日：2013-08-02

Applicant: Feng Xue ,  Qinghua Li ,  Huaning Niu ,  Jong-Kae Fwu

Inventor： Feng Xue ,  Qinghua Li ,  Huaning Niu ,  Jong-Kae Fwu

IPC: H04W72/04 ,  H04L1/18 ,  H04W76/02

CPC classification number: H04W72/042 ,  H04L1/1854 ,  H04L1/1861 ,  H04L1/1887 ,  H04W72/0413 ,  H04W72/044 ,  H04W76/14 ,  Y02D70/126 ,  Y02D70/20

Abstract: Described are methods and devices for enabling D2D communications with signal structures that require minimal changes to the current LTE architecture. In the embodiments described, the eNB grants resources to UEs for D2D communication and either initiates or permits a pair of UEs to establish a D2D link. Certain embodiments are designed to minimize changes to the current LTE control signaling structure by having the control signaling always come from the eNB as in a normal cellular link so that the transmitting UE transmits over a data channel (e.g., PUSCH/PDSCH) that the receiving UE is able to decode.

Abstract translation: 描述了用于实现与当前LTE架构的最小改变的信号结构的D2D通信的方法和设备。 在所描述的实施例中，eNB向用于D2D通信的UE授予资源，并且启动或允许一对UE建立D2D链路。 某些实施例被设计为通过使控制信令总是来自于正常蜂窝链路中的eNB来使得当前LTE控制信令结构的变化最小化，使得发送UE通过数据信道（例如，PUSCH / PDSCH）发送接收 UE能够解码。

公开(公告)号：US08942914B2

公开(公告)日：2015-01-27

申请号：US13032176

申请日：2011-02-22

Applicant: Rajesh Venkat Subbu ,  Feng Xue ,  Mauricio Castillo-Effen ,  Joel Kenneth Klooster ,  Joachim Karl Hochwarth ,  Sergio Torres ,  Weiwei Chen

Inventor： Rajesh Venkat Subbu ,  Feng Xue ,  Mauricio Castillo-Effen ,  Joel Kenneth Klooster ,  Joachim Karl Hochwarth ,  Sergio Torres ,  Weiwei Chen

IPC: G06F19/00 ,  G08G5/00 ,  G08G5/02

CPC classification number: G08G5/0013 ,  G08G5/0043 ,  G08G5/0082 ,  G08G5/02

Abstract: Methods and system are provided for scheduling and negotiating air traffic within an airspace surrounding an airport and scheduled to land at the airport. An air traffic control (ATC) system is used to monitor the altitudes, speeds and lateral routes of aircraft. The ATC system generates a scheduled time-of-arrival (STA) at one or more meter fix points associated with the airport, the STA is stored, and data is received or inferred with the ATC system for at least a first of the aircraft, including a minimum fuel-cost speed and predicted trajectory parameters of the first aircraft based on current values of its existing trajectory parameters. Auxiliary data, including earliest and latest estimated time-of-arrival (ETAmin) and (ETAmax) at the meter fix point, STA being within/ outside ETAmin, ETAmax are generated, instructions are transmitted to the first aircraft, and the STA is updated for each aircraft stored in a queue.

Abstract translation: 提供方法和系统，用于在机场周围的空域内安排和谈判空中交通，并计划在机场降落。 空中交通管制（ATC）系统用于监测飞机的高度，速度和侧向航路。 ATC系统在与机场相关联的一个或多个仪表固定点处产生预定的到达时间（STA），STA被存储，并且用ATC系统接收或推断用于至少第一飞行器的数据， 包括基于其现有轨迹参数的当前值的最小燃料成本速度和第一飞机的预测轨迹参数。 产生辅助数据，包括在仪表固定点的最早和最近的估计到达时间（ETAmin）和（ETAmax），在ETAmin内/ ETAmin内的STA，ETAmax，指令被发送到第一飞行器，并且STA被更新 对于存储在队列中的每架飞机。

公开(公告)号：US08606491B2

公开(公告)日：2013-12-10

申请号：US13032101

申请日：2011-02-22

Applicant: Rajesh Venkat Subbu ,  Feng Xue ,  Mauricio Castillo-Effen ,  Joel Kenneth Klooster ,  Joachim Karl Hochwarth ,  Sergio Torres ,  Weiwei Chen

Inventor： Rajesh Venkat Subbu ,  Feng Xue ,  Mauricio Castillo-Effen ,  Joel Kenneth Klooster ,  Joachim Karl Hochwarth ,  Sergio Torres ,  Weiwei Chen

IPC: G08G5/00 ,  G08G5/04

CPC classification number: G08G5/0043 ,  G06Q10/047 ,  G06Q10/06 ,  G06Q50/30

Abstract: Methods and systems suitable for negotiating air traffic trajectory modification requests received from multiple aircraft that each has trajectory parameters. The methods include transmitting from at least a first aircraft a first trajectory modification request to alter the altitude, speed and/or lateral route thereof. A first conflict assessment is then performed to determine if the first trajectory modification request poses a conflict with the altitudes, speeds and lateral routes of other aircraft. If a conflict is not identified, the first trajectory modification request is granted and the first aircraft is notified of the first trajectory modification request being granted. Alternatively, if a conflict is identified, the first trajectory modification request is not granted and the first aircraft is notified thereof. If the first trajectory modification request was not granted, the first trajectory modification request is placed in a queue, which is periodically processed to perform subsequent conflict assessments.

Abstract translation: 适用于协商从多台飞机接收的空中交通轨迹修改请求的方法和系统，每个航空器具有轨迹参数。 所述方法包括从至少第一飞行器发送第一轨迹修改请求以改变其高度，速度和/或横向路线。 然后执行第一冲突评估以确定第一轨迹修改请求是否与其他飞行器的高度，速度和侧向路线形成冲突。 如果没有识别到​​冲突，则授予第一轨迹修改请求，并且向第一飞机通知被授予的第一轨迹修改请求。 或者，如果确定了冲突，则未授予第一轨迹修改请求，并且通知第一飞行器。 如果未授予第一轨迹修改请求，则将第一轨迹修改请求放置在队列中，该队列被周期性地处理以执行随后的冲突评估。

公开(公告)号：US20120215435A1

公开(公告)日：2012-08-23

申请号：US13032176

申请日：2011-02-22

Applicant: Rajesh Venkat Subbu ,  Feng Xue ,  Mauricio Castillo-Effen ,  Joel Kenneth Klooster ,  Joachim Karl Hochwarth ,  Sergio Torres ,  Weiwei Chen

Inventor： Rajesh Venkat Subbu ,  Feng Xue ,  Mauricio Castillo-Effen ,  Joel Kenneth Klooster ,  Joachim Karl Hochwarth ,  Sergio Torres ,  Weiwei Chen

IPC: G08G5/00

CPC classification number: G08G5/0013 ,  G08G5/0043 ,  G08G5/0082 ,  G08G5/02

Abstract: Methods and systems scheduling and negotiating air traffic within an airspace surrounding an airport and scheduled to land at the airport. An air traffic control (ATC) system is used to monitor the altitudes, speeds and lateral routes of aircraft as they enter the airspace. The ATC system generates a scheduled time-of-arrival (STA) for each aircraft at one or more meter fix points associated with the airport, the STA for each aircraft is stored, and data is received or inferred with the ATC system for at least a first of the aircraft, including a minimum fuel-cost speed and predicted trajectory parameters of the first aircraft based on current values of its existing trajectory parameters. Auxiliary data, including earliest and latest estimated time-of-arrival ETAmin and ETAmax at the meter fix point, are generated for the first aircraft using the predicted trajectory parameters. The ATC system determines whether the STA of the first aircraft is in or outside an ETA range bounded by its ETAmin and ETAmax. Instructions are transmitted to the first aircraft to ensure its arrival at the meter fix point at the STA or the ETAmin of the first aircraft, and the STA is updated for each aircraft stored in the queue.

Abstract translation: 方法和系统安排和谈判机场周围空域内的空中交通，并计划在机场降落。 空中交通管制（ATC）系统用于监控飞机进入空域时的高度，速度和侧向航路。 ATC系统在与机场相关联的一个或多个仪表固定点处为每个飞行器生成预定的到达时间（STA），存储每个飞行器的STA，并且至少与ATC系统接收或推断数据 基于现有轨迹参数的当前值，飞行器中的第一个，包括最低燃料成本速度和第一架飞机的预测轨迹参数。 使用预测的轨迹参数为第一架飞机生成辅助数据，包括最早和最近的估计到达时间ETAmin和仪表固定点的ETAmax。 ATC系统确定第一架飞机的STA是否处于由其ETAmin和ETAmax所限定的ETA范围之内或之外。 指令被发送到第一台飞机，以确保其到达STA的第一台飞机的米座固定点或第一架飞机的ETAmin，并为存储在队列中的每架飞机更新STA。

公开(公告)号：US20100332508A1

公开(公告)日：2010-12-30

申请号：US12495022

申请日：2009-06-30

Applicant: Steven Matt Gustafson ,  Abha Moitra ,  Feng Xue ,  David Brian Bracewell ,  Jesse Neuendank Schechter

Inventor： Steven Matt Gustafson ,  Abha Moitra ,  Feng Xue ,  David Brian Bracewell ,  Jesse Neuendank Schechter

IPC: G06F17/30

CPC classification number: G06Q30/02 ,  G06F16/951

Abstract: Extracting and analyzing online discussions to identify prospects of a subject is provided. The method has steps including initializing queries related to the subject and a set of data sources utilizing subject information and one or more data source names, extracting the discussions from the set of data sources by employing the queries, extracting significant discussions from the extracted discussions by applying discussions quality methods, identifying websites corresponding to the significant discussions; extracting significant websites by applying websites quality methods to the identified websites, determining a website influence of each of the significant websites by determining their corresponding attributes, identifying a discussion influence of each of the significant discussions based on the website influence of each of the corresponding significant websites, and weighting the significant discussions and the significant websites utilizing the discussion influence and the website influence of each of the significant discussions and the significant websites, respectively.

Abstract translation: 提供和分析在线讨论以确定主题的前景。 该方法具有以下步骤：初始化与该主题相关的查询和使用主题信息和一个或多个数据源名称的一组数据源，通过采用查询从该组数据源提取讨论，从提取的讨论中提取重要的讨论，由 应用讨论质量方法，识别与重大讨论对应的网站; 通过将网站质量方法应用于确定的网站，提取重要网站，通过确定每个重要网站的相应属性来确定每个重要网站的网站影响，根据每个相关重要网站的网站影响，确定每个重要讨论的讨论影响 网站，并分别对每个重要讨论和重要网站的讨论影响力和网站影响力进行重大讨论和重要网站的权重。

公开(公告)号：US20080219251A1

公开(公告)日：2008-09-11

申请号：US11715547

申请日：2007-03-08

Applicant: Feng Xue ,  Sumeet Sandhu

Inventor： Feng Xue ,  Sumeet Sandhu

IPC: H04L12/56

CPC classification number: H04L1/0041 ,  H03M13/1102 ,  H03M13/13 ,  H03M13/23 ,  H03M13/29 ,  H03M13/2903 ,  H04L45/24 ,  H04L2001/0093 ,  H04L2001/0097

Abstract: A method of transmitting two packets to two different nodes may include encoding a first packet according to a first channel to obtain an encoded first packet and encoding a second packet according to a second channel different than the first channel to obtain an encoded second packet. The encoded first packet and the encoded second packet may be combined to obtain a combined encoded packet. The method may include mapping the combined encoded packet to symbols for transmission. The symbols may be transmitted to the two different nodes over the first channel and the second channel.

Abstract translation: 将两个分组发送到两个不同节点的方法可以包括根据第一信道编码第一分组以获得编码的第一分组，并且根据与第一信道不同的第二信道对第二分组进行编码以获得编码的第二分组。 编码的第一分组和编码的第二分组可以被组合以获得组合的编码分组。 该方法可以包括将组合的编码分组映射到用于传输的符号。 符号可以在第一信道和第二信道上被发送到两个不同的节点。