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公开(公告)号:US20180002433A1
公开(公告)日:2018-01-04
申请号:US15614149
申请日:2017-06-05
Applicant: Genentech, Inc.
Inventor: Yin Zhang , Joy Yu Zuchero , Jasvinder Atwal , Jessica Couch , Mark S. Dennis , James A. Ernst , Ryan J. Watts , Gregory A. Lazar
Abstract: The present invention relates to anti-transferrin receptor antibodies and methods of their use.
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公开(公告)号:US09708406B2
公开(公告)日:2017-07-18
申请号:US14283038
申请日:2014-05-20
Applicant: Genentech, Inc.
Inventor: Yin Zhang , Joy Yu Zuchero , Jasvinder Atwal , Jessica Couch , Mark S. Dennis , James A. Ernst , Ryan J. Watts , Gregory A. Lazar
CPC classification number: C07K16/2881 , A61K39/3955 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K16/40 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/41 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/71 , C07K2317/72 , C07K2317/732 , C07K2317/92 , C07K2317/94
Abstract: The present invention relates to anti-transferrin receptor antibodies and methods of their use.
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公开(公告)号:US09593167B2
公开(公告)日:2017-03-14
申请号:US14517682
申请日:2014-10-17
Applicant: Genentech, Inc.
Inventor: Mark S. Dennis , Bonnee Rubinfeld , Paul Polakis , Aya Jakobovits
IPC: C07K16/00 , C07K16/40 , A61K47/48 , A61K49/00 , A61K51/10 , C07K16/30 , A61K38/05 , A61K39/395 , A61K45/06 , A61K39/00
CPC classification number: G01N33/57434 , A61K38/05 , A61K39/39558 , A61K45/06 , A61K47/6851 , A61K47/6869 , A61K47/6871 , A61K49/0002 , A61K49/0058 , A61K51/1045 , A61K51/1072 , A61K2039/505 , C07K16/30 , C07K16/3069 , C07K16/40 , C07K17/00 , C07K2317/24 , C07K2317/31 , C07K2317/515 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/622 , C07K2317/92
Abstract: Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP-1 antibodies and immunoconjugates thereof are provided.
Abstract translation: 提供抗STEAP-1抗体及其免疫偶联物。 提供了使用抗STEAP-1抗体及其免疫偶联物的方法。
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公开(公告)号:US20170044261A1
公开(公告)日:2017-02-16
申请号:US15079804
申请日:2016-03-24
Applicant: Genentech, Inc.
Inventor: Sherman Fong , Mark S. Dennis
IPC: C07K16/28
CPC classification number: C07K16/2839 , A61K2039/505 , C07K16/18 , C07K16/2827 , C07K2317/14 , C07K2317/24 , C07K2317/41 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/92
Abstract: The invention provides therapeutic anti-beta7 antibodies, compositions comprising, and methods of using these antibodies.
Abstract translation: 本发明提供了治疗性抗-β7抗体,组合物和使用这些抗体的方法。
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公开(公告)号:US20160368994A1
公开(公告)日:2016-12-22
申请号:US15182327
申请日:2016-06-14
Applicant: Genentech, Inc.
Inventor: Robert F. Kelley , Steven R. Leong , Wei-Ching Liang , Mary Mathieu , Andrew G. Polson , Bing Zheng , Xiaocheng Chen , Cecilia Pui Chi Chiu , Mark S. Dennis , Allen Ebens , Yan Wu
IPC: C07K16/28 , A61K45/06 , A61K39/395
CPC classification number: C07K16/2851 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/507 , A61K2039/57 , C07K16/2803 , C07K16/2809 , C07K16/2827 , C07K16/3061 , C07K2317/14 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/40 , C07K2317/41 , C07K2317/52 , C07K2317/526 , C07K2317/55 , C07K2317/56 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/90 , C07K2317/92 , C07K2317/94
Abstract: The present invention relates to anti-CLL-1 antibodies including anti-CLL-1 antibodies comprising a CLL-1 binding domain and a CD3 binding domain (e.g., anti-CLL-1/CD3 T cell dependent bispecific (TDB) antibody) and methods of using the same.
Abstract translation: 本发明涉及包含CLL-1结合结构域和CD3结合结构域(例如,抗CLL-1 / CD3T细胞依赖性双特异性(TDB)抗体)的抗CLL-1抗体的抗CLL-1抗体, 使用方法
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36.ANTI-IL-4 ANTIBODIES AND BISPECIFIC ANTIBODIES AND USES THEREOF 审中-公开
Title translation: 抗IL-4抗体和双抗体抗体及其用途公开(公告)号:US20160207995A1
公开(公告)日:2016-07-21
申请号:US14858251
申请日:2015-09-18
Applicant: Genentech, Inc.
Inventor: Daniel G. Yansura , Nancy Y. Chiang , Mark S. Dennis , Michael Dillon , Germaine G. Fuh , Gerald R. Nakamura , Christoph Spiess , Lawren C. Wu , Yin Zhang
IPC: C07K16/24 , A61K45/06 , A61K39/395
CPC classification number: C07K16/247 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K16/244 , C07K2317/14 , C07K2317/24 , C07K2317/31 , C07K2317/51 , C07K2317/56 , C07K2317/76 , C07K2317/92
Abstract: The invention provides anti-IL-4 antibodies and bispecific antibodies and methods of using the same.
Abstract translation: 本发明提供抗IL-4抗体和双特异性抗体及其使用方法。
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公开(公告)号:US20150197560A1
公开(公告)日:2015-07-16
申请号:US14454884
申请日:2014-08-08
Applicant: GENENTECH, INC.
Inventor: Sherman Fong , Mark S. Dennis
IPC: C07K16/18
CPC classification number: C07K16/2839 , A61K2039/505 , C07K16/18 , C07K16/2827 , C07K2317/14 , C07K2317/24 , C07K2317/41 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/92
Abstract: The invention provides therapeutic anti-beta7 antibodies, compositions comprising, and methods of using these antibodies.
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公开(公告)号:US20130149307A1
公开(公告)日:2013-06-13
申请号:US13668028
申请日:2012-11-02
Applicant: Genentech, Inc.
Inventor: Weilan Ye , Mark S. Dennis , Jill Fredrickson
IPC: C07K16/18 , A61K39/395 , A61K45/06 , A61K39/00 , A61K31/519 , A61K38/19 , A61K31/555 , A61K31/337 , A61K31/513 , C07K16/22 , A61K31/56
CPC classification number: C07K16/22 , A61K31/282 , A61K31/337 , A61K31/513 , A61K31/519 , A61K31/555 , A61K31/56 , A61K38/19 , A61K39/0011 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/18 , C07K16/46 , C07K16/468 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92
Abstract: The present invention concerns antibodies to EGFL7 and the uses of same.
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公开(公告)号:US20130129749A1
公开(公告)日:2013-05-23
申请号:US13668086
申请日:2012-11-02
Applicant: Genentech, Inc.
Inventor: Weilan Ye , Mark S. Dennis , Jill Fredrickson
IPC: C07K16/18 , A61K31/337 , A61K31/282 , A61K39/395 , A61K31/513
CPC classification number: C07K16/22 , A61K31/282 , A61K31/337 , A61K31/513 , A61K31/519 , A61K31/555 , A61K31/56 , A61K38/19 , A61K39/0011 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/18 , C07K16/46 , C07K16/468 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92
Abstract: The present invention concerns antibodies to EGFL7 and the uses of same.
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