Mutagenized strain of Glarea lozoyensis and a method of preparing a compound from the mutagenized strain
    31.
    发明授权
    Mutagenized strain of Glarea lozoyensis and a method of preparing a compound from the mutagenized strain 失效
    变形菌株Glarea lozoyensis和从诱变菌株制备化合物的方法

    公开(公告)号:US08431383B2

    公开(公告)日:2013-04-30

    申请号:US13497927

    申请日:2009-09-28

    CPC classification number: C12R1/645 C07K7/56 C12N15/01

    Abstract: High yield antibiotics producing fungus strain, preparation method and use thereof are provided. The fungus strain is a mutant derived from Glarea lozoyensis, and deposited in CGMCC with the accession number of CGMCC 2933. The preparation method concludes following steps: (a) mixing the culture media of Glarea lozoyensis strain ATCC 20957 with nitrosoguanidine, and obtaining mixture a; (b) mixing lywallzyme with the mixture a, and obtaining protoplasts; (c) regenerating the protoplasts, and obtaining single clones; and (d) culturing the single clones, then obtaining the mutant strain. This fungus strain has stable genetic and producing property, produces little impurities in fermentation, and is suitable to be used in industry.

    Abstract translation: 提供生产真菌菌株的高产抗生素,其制备方法和用途。 真菌菌株是来自山茱萸的突变体,保藏于CGMCC,保藏号为CGMCC 2933.制备方法的结论如下:(a)将葛兰氏杆菌菌株ATCC 20957的培养基与亚硝基胍混合,得到混合物 ; (b)将溶菌酶与混合物a混合,得到原生质体; (c)再生原生质体,获得单个克隆; 和(d)培养单个克隆,然后获得突变株。 该真菌菌株具有稳定的遗传和生产性能,在发酵中产生的杂质少,适用于工业。

    Base Station Aided Mobile-Relay Candidate Pre-Selection and Pre-Deployment
    33.
    发明申请
    Base Station Aided Mobile-Relay Candidate Pre-Selection and Pre-Deployment 有权
    基站辅助移动接力候选预选和预部署

    公开(公告)号:US20120315841A1

    公开(公告)日:2012-12-13

    申请号:US13578753

    申请日:2010-02-26

    CPC classification number: H04B7/2606 H04B7/15507 H04W76/14 H04W88/04

    Abstract: In one exemplary embodiment a network node (such as a base station BS) determines that a plurality of user equipments UEs are available for use as mobile relays MRs, and selects a subset of the plurality of UEs and configures the subset of the plurality of UEs as MRs. In another exemplary embodiment, an indication is sent (for example from a UE) that a UE is willing to operate as a MR, a response is received that the UE is selected to be a MR1 and then periodically there is sent a beacon advertising that the UE is a MR. In this manner UEs are pre-configured in a cell as MRs, regardless of any specific UE need for relay services. Any UE later needing relay service listens for the beacon. The BS can limit which UEs it pre-configures as MRs to avoid closely spaced UEs being both active MRs. Locations need not be signaled.

    Abstract translation: 在一个示例性实施例中,网络节点(例如基站BS)确定多个用户设备UE可用作移动中继站MR,并且选择多个UE的子集并且配置多个UE的子集 作为MR。 在另一个示例性实施例中,UE(例如,从UE)发出指示,该UE指示UE愿意作为MR操作,接收到响应被选择为MR1,然后周期性地发送信标, UE是MR。 以这种方式,UE在小区中被预配置为MR,而不管UE对于中继服务的任何特定UE的需求。 任何UE后来需要中继服务监听信标。 BS可以限制预先配置为MR的哪些UE,以避免紧密间隔的UE是主动MR。 地点不需要发出信号。

    PREPARATION METHOD FOR MOLECULAR RECOGNITION SENSOR BY ELECTRODEPOSITION
    34.
    发明申请
    PREPARATION METHOD FOR MOLECULAR RECOGNITION SENSOR BY ELECTRODEPOSITION 有权
    通过电沉积制备分子识别传感器的方法

    公开(公告)号:US20120285833A1

    公开(公告)日:2012-11-15

    申请号:US13562410

    申请日:2012-07-31

    CPC classification number: G01N33/5438 G01N27/3275

    Abstract: A preparation method for molecular recognition sensor by electrodeposition is provided. The preparation method is as following: forming molecularly imprinted polymeric micelles by self-assembly of ionic type photosensitive copolymers; forming a film on the surface of an electrode by electrodepositing the molecularly imprinted polymeric micelles at a constant potential; crosslinking the electrodeposited micellar film via ultraviolet light irradiation; extracting the template molecules from the crosslinked film to obtain electrode modified by the molecularly imprinted polymeric micellar film; and connecting the modified electrode with a sensor device and a computer to construct a molecular recognition sensing system capable of specifically detecting the template molecules.

    Abstract translation: 提供了通过电沉积分子识别传感器的制备方法。 制备方法如下:通过离子型光敏共聚物的自组装形成分子印迹的聚合胶束; 通过以恒定电位沉积分子印迹的聚合物胶束在电极的表面上形成膜; 通过紫外光照射交联电沉积胶束膜; 从交联膜中提取模板分子,得到由分子印迹聚合物胶束膜改性的电极; 并且将修改的电极与传感器装置和计算机连接以构建能够特异性检测模板分子的分子识别感测系统。

    HIGH YIELD ANTIBIOTICS PRODUCING FUNGUS STRAIN, PREPARATION METHOD AND USE THEREOF
    35.
    发明申请
    HIGH YIELD ANTIBIOTICS PRODUCING FUNGUS STRAIN, PREPARATION METHOD AND USE THEREOF 失效
    生产真菌菌株的高效抗生素,制备方法及其应用

    公开(公告)号:US20120258498A1

    公开(公告)日:2012-10-11

    申请号:US13497927

    申请日:2009-09-28

    CPC classification number: C12R1/645 C07K7/56 C12N15/01

    Abstract: High yield antibiotics producing fungus strain, preparation method and use thereof are provided. The fungus strain is a mutant derived from Glarea lozoyensis, and deposited in CGMCC with the accession number of CGMCC 2933. The preparation method concludes following steps: (a) mixing the culture media of Glarea lozoyensis strain ATCC 20957 with nitrosoguanidine, and obtaining mixture a; (b) mixing lywallzyme with the mixture a, and obtaining protoplasts; (c) regenerating the protoplasts, and obtaining single clones; and (d) culturing the single clones, then obtaining the mutant strain. This fungus strain has stable genetic and producing property, produces little impurities in fermentation, and is suitable to be used in industry.

    Abstract translation: 提供生产真菌菌株的高产抗生素,其制备方法和用途。 真菌菌株是来自山茱萸的突变体,保藏于CGMCC,保藏号为CGMCC 2933.制备方法的结论如下:(a)将葛兰氏杆菌菌株ATCC 20957的培养基与亚硝基胍混合,得到混合物 ; (b)将溶菌酶与混合物a混合,得到原生质体; (c)再生原生质体,获得单个克隆; 和(d)培养单个克隆,然后获得突变株。 该真菌菌株具有稳定的遗传和生产性能,在发酵中产生的杂质少,适用于工业。

    High temperature electrochemical characterization of molten metal corrosion
    38.
    发明授权
    High temperature electrochemical characterization of molten metal corrosion 有权
    熔融金属腐蚀的高温电化学表征

    公开(公告)号:US08173007B2

    公开(公告)日:2012-05-08

    申请号:US12128954

    申请日:2008-05-29

    CPC classification number: G01N27/411

    Abstract: A system and method for the high temperature in-situ determination of corrosion characteristics of a molten metal on an alloy under study is provided which takes place within an insulated furnace. A graphite crucible provided in the furnace contains an electrolyte formed from a molten salt of a metal halide. A reference electrode formed from the same metal as the electrolyte is immersed in the electrolyte solution in the graphite crucible. A beta-alumina crucible containing a molten metal is also provided within the furnace and preferably within the graphite crucible. A measuring electrode formed from the alloy under study is immersed in the molten metal. Standard electrochemical techniques are used to measure and analyze the electrochemical effects of corrosion of the molten metal on the alloy.

    Abstract translation: 提供了一种在绝缘炉内进行高温原位测定熔融金属在正在研究的合金上的腐蚀特性的系统和方法。 设置在炉中的石墨坩埚含有由金属卤化物的熔融盐形成的电解质。 由与电解质相同的金属形成的参比电极浸入石墨坩埚中的电解液中。 在炉内还优选在石墨坩埚内提供含有熔融金属的β-氧化铝坩埚。 将由研究的合金形成的测量电极浸入熔融金属中。 使用标准电化学技术来测量和分析熔融金属对合金的腐蚀的电化学效应。

    Fusion proteins having mutated immunoglobulin hinge region
    40.
    发明授权
    Fusion proteins having mutated immunoglobulin hinge region 有权
    具有突变的免疫球蛋白铰链区的融合蛋白

    公开(公告)号:US08067548B2

    公开(公告)日:2011-11-29

    申请号:US12180455

    申请日:2008-07-25

    Abstract: A fusion protein having a non-immunoglobulin polypeptide having a cysteine residue proximal to the C terminal thereof, and an immunoglobulin component with a mutated hinge region is provided. The mutation comprises a point mutated site corresponding in position to the position in a native hinge region of the cysteine residue located nearest the cysteine residue of the non-Ig component. The distance from the cysteine residue of the non-immunoglobulin polypeptide and any remaining cysteine residues of the mutated hinge region is sufficient to prevent the formation of a disulphide bond therebetween.

    Abstract translation: 提供了具有非免疫球蛋白多肽的融合蛋白,其具有接近其C末端的半胱氨酸残基和具有突变的铰链区的免疫球蛋白组分。 该突变包括位于位于最接近非Ig组分的半胱氨酸残基的半胱氨酸残基的天然铰链区的位置的点突变位点。 与非免疫球蛋白多肽的半胱氨酸残基和突变的铰链区的任何剩余半胱氨酸残基的距离足以防止其间形成二硫键。

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