公开(公告)号：US20080077125A1

公开(公告)日：2008-03-27

申请号：US11950751

申请日：2007-12-05

Applicant: John Swoyer ,  Yelena Tropsha ,  Julie Woessner ,  Mark Christopherson

Inventor： John Swoyer ,  Yelena Tropsha ,  Julie Woessner ,  Mark Christopherson

IPC: A61B18/18

CPC classification number: A61B18/1477 ,  A61B2018/1472 ,  A61B2018/1475

Abstract: Methods and apparatus for ablating a target tissue are discussed. Such methods and apparatus include those that simplify tissue ablation. For example, a tissue ablation device having an actuator, such as a trigger mechanism, coupled to a power source and an electrode is discussed. A single step of engaging the actuator causes the electrode to be introduced into the target tissue and causes energy to be delivered from the power supply to the tissue via the electrode. By way of additional example, a tissue ablation device having an actuator coupled to a fluid source and an electrode is discussed. A single step of engaging the actuator causes conductive fluid to flow from the fluid source to the target tissue location and causes the electrode to be introduced to the target tissue location. The fluid source may be a conductive fluid, such as saline, which may increase the efficiency of ablation. Various other configurations and methods that simplify tissue ablation are also discussed.

Abstract translation: 讨论了用于烧蚀靶组织的方法和装置。 这些方法和装置包括简化组织消融的方法和装置。 例如，讨论了具有耦合到电源和电极的诸如触发机构的致动器的组织消融装置。 使执行器接合的一个步骤使得电极被引入目标组织中，并且通过电极将能量从电源传送到组织。 作为另外的示例，讨论了具有耦合到流体源和电极的致动器的组织消融装置。 使致动器接合的一个步骤导致导电流体从流体源流动到目标组织位置，并且使电极被引入目标组织位置。 流体源可以是诸如盐水的导电流体，其可以提高消融效率。 还讨论了简化组织消融的各种其它配置和方法。

公开(公告)号：US20070179496A1

公开(公告)日：2007-08-02

申请号：US11343967

申请日：2006-01-31

Applicant: John Swoyer ,  Martin Gerber

Inventor： John Swoyer ,  Martin Gerber

IPC: A61B18/14

CPC classification number: A61B18/1492 ,  A61B18/1477 ,  A61B2017/00274 ,  A61B2018/00285 ,  A61B2018/00547 ,  A61B2018/1425 ,  A61B2018/1472 ,  A61B2018/1475

Abstract: The disclosure describes a system that may be used to deliver ablation therapy to a target tissue within a patient. The system uses a flexible catheter to navigate through a passage and reach a target tissue. Once at the desired location, a side of the flexible catheter is forced against a wall of the passage to allow a needle to be extended from the side of the flexible catheter and into the target tissue. A pull-wire or inflatable balloon may be used as the control mechanism that forces the flexible catheter against the passage wall. In the case of the pull-wire, the flexible catheter may also be steered through the passage. As an example, the flexible catheter may be inserted into the urethra and the needle may be deployed into the prostate to treat benign prostatic hypertrophy (BPH).

Abstract translation: 本公开描述了可用于向患者内的靶组织递送消融治疗的系统。 该系统使用柔性导管穿过通道并到达目标组织。 一旦在期望的位置，柔性导管的一侧被迫抵靠通道的壁，以允许针从柔性导管的一侧延伸并进入目标组织。 可以使用拉线或可膨胀气囊作为将柔性导管压靠通道壁的控制机构。 在拉线的情况下，柔性导管也可以通过通道转向。 作为示例，柔性导管可以插入尿道中，针可以部署到前列腺中以治疗良性前列腺肥大（BPH）。

公开(公告)号：US20070100386A1

公开(公告)日：2007-05-03

申请号：US11263526

申请日：2005-10-31

Applicant: Carole Tronnes ,  Robert Munoz ,  Alexander Lakanu ,  John Swoyer ,  Greg Theis ,  Bryan Zart ,  David DeSmet

Inventor： Carole Tronnes ,  Robert Munoz ,  Alexander Lakanu ,  John Swoyer ,  Greg Theis ,  Bryan Zart ,  David DeSmet

IPC: A61N1/00

CPC classification number: A61N1/3752 ,  Y10T29/49208

Abstract: The disclosure describes an axial lead connector assembly for an implantable medical device (IMD). The lead connector assembly facilitates electrical connection between an implantable medical lead and circuitry contained within the housing of an IMD. A connector header defines an axial stack bore to receive an axial stack of in-line connector components. The connector components define a common lead bore to receive a proximal end of an implantable lead. The in-line stack of connector components may include seals, electrical connector elements, a strain relief, and a locking device, each of which defines a passage that forms part of the lead bore.

Abstract translation: 本公开描述了用于可植入医疗装置（IMD）的轴向引线连接器组件。 导线连接器组件有助于可植入医疗引线和包含在IMD的壳体内的电路之间的电连接。 连接器插头限定轴向堆叠孔以接收轴向堆叠的在线连接器部件。 连接器部件限定了用于接收可植入引线的近端的公共引线孔。 连接器部件的直列堆叠可以包括密封件，电连接器元件，应变消除件和锁定装置，每个锁定装置限定形成引导孔的一部分的通道。

公开(公告)号：US20060229601A1

公开(公告)日：2006-10-12

申请号：US11419662

申请日：2006-05-22

Applicant: John Swoyer ,  Yelena Tropsha ,  Julie Woessner ,  Mark Christopherson

Inventor： John Swoyer ,  Yelena Tropsha ,  Julie Woessner ,  Mark Christopherson

IPC: A61B18/18 ,  A61N1/00

CPC classification number: A61B18/14 ,  A61B2018/00077 ,  A61B2018/00148 ,  A61B2018/1472

Abstract: Delivery elements, including needle electrodes and sheaths of tissue ablation devices, containing a conductivity-enhancing agent are discussed. The delivery elements contain a body member and optionally one or more coating layers. The conductivity-enhancing agent is disposed on or in the body member and/or at least one of the one or more coating layers. The conductivity-enhancing agent is capable of eluting from the delivery element when the delivery element is contacted with bodily tissue or fluid and increases conductivity of the tissue, making tissue ablation more efficient.

Abstract translation: 讨论了包含导电性增强剂的递送元件，包括组织消融装置的针电极和护套。 递送元件包含主体部件和可选的一个或多个涂层。 导电性增强剂设置在主体部件中和/或主体部件和/或一个或多个涂层中的至少一个上。 当递送元件与身体组织或流体接触并且增加组织的电导率时，导电性增强剂能够从递送元件洗脱，从而使组织消融更有效率。

公开(公告)号：US20060129218A1

公开(公告)日：2006-06-15

申请号：US11352552

申请日：2006-02-13

Applicant: John Swoyer ,  Keith Carlton ,  Martin Gerber ,  George Mamo ,  Michele Spinelli ,  Steven Hartle

Inventor： John Swoyer ,  Keith Carlton ,  Martin Gerber ,  George Mamo ,  Michele Spinelli ,  Steven Hartle

IPC: A61N1/05

CPC classification number: A61N1/0558 ,  A61N1/0551

Abstract: An implantable medical electrical lead particularly for stimulation of the sacral nerves comprises a lead body extending between a distal end and a proximal end, and the distal end having at least one electrode of an electrode array extending longitudinally from the distal end toward the proximal end. The lead body at its proximal end may be coupled to a pulse generator, additional intermediate wiring, or other stimulation device. A fixation mechanism is formed on or integrally with the lead body proximal to the electrode array that is adapted to be implanted in and engage subcutaneous tissue, particularly muscle tissue, to inhibit axial movement of the lead body and dislodgement of the stimulation electrodes. The fixation mechanism comprises a M tine elements arrayed in a tine element array along a segment of the lead proximal to the stimulation electrode array. Each tine element comprises at least N flexible, pliant, tines, each tine having a tine width and thickness and extending through a tine length from an attached tine end to a free tine end. The attached tine end is attached to the lead body from a tine attachment site and supports the tine extending outwardly of the lead body and proximally toward the lead proximal end. The M×N tines are adapted to be folded inward against the lead body when fitted into and constrained by the lumen of an introducer such that the tine free ends of more distal tines of more distal tine elements are urged toward or alongside the attached tine ends of the adjacent more proximal tines of more proximal tine elements, and the folded tines do not overlap one another.

公开(公告)号：US20050096629A1

公开(公告)日：2005-05-05

申请号：US10698100

申请日：2003-10-31

Applicant: Martin Gerber ,  John Swoyer

Inventor： Martin Gerber ,  John Swoyer

IPC: A61B17/00 ,  A61B17/34 ,  A61M5/142 ,  A61M5/168 ,  A61M31/00

CPC classification number: A61M5/14216 ,  A61B17/3478 ,  A61B2017/00274 ,  A61B2018/00547 ,  A61M5/16809

Abstract: The invention is directed to a technique for delivering a denervating agent to a patient's prostate gland. In particular, the invention is directed to a transurethral technique for delivering the denervating agent. Devices and systems are also described for use in implementing the technique.

Abstract translation: 本发明涉及一种将去神经抑制剂递送至患者前列腺的技术。 特别地，本发明涉及用于递送去神经纤维素的经尿道技术。 还描述了用于实施该技术的设备和系统。

公开(公告)号：US09427571B2

公开(公告)日：2016-08-30

申请号：US13538074

申请日：2012-06-29

Applicant: Shahn S. Sage ,  Tom Walch ,  Martin T. Steele, Sr. ,  John Swoyer

Inventor： Shahn S. Sage ,  Tom Walch ,  Martin T. Steele, Sr. ,  John Swoyer

IPC: A61N1/05 ,  A61N1/36

CPC classification number: A61N1/0551 ,  A61N1/056 ,  A61N1/3605 ,  Y10T29/49117

Abstract: An implantable biomedical conductor assembly is configured for at least partial insertion in a living body. The implantable conductor assembly includes an inner tubular structure and an outer tubular structure generally surrounding the inner tubular structures such that a gap of less than about 0.030 inches exists there between. A dynamic coil is located in the gap. The dynamic coil includes a plurality of insulated conductors that are coiled generally at or below a yield point. The insulated conductors are permitted to expand within the gap to engage an inner surface of the outer tubular structure in an expanded coiled configuration. At least one mechanical restraint at each of a distal end and a proximal end retains the dynamic coil in the tubular structures. Free ends of the insulated conductors extend beyond the proximal and distal ends to facilitate attachment to electrodes and connectors.

Abstract translation: 可植入生物医学导体组件被配置为至少部分地插入生物体内。 可植入导体组件包括内部管状结构和通常围绕内部管状结构的外部管状结构，使得在其间存在小于约0.030英寸的间隙。 动态线圈位于间隙中。 动态线圈包括多个绝缘导体，其通常在屈服点以下或以下盘绕。 允许绝缘导体在间隙内扩张，以扩展的线圈构型接合外部管状结构的内表面。 在远端和近端中的每一个处的至少一个机械约束将动态线圈保持在管状结构中。 绝缘导体的自由端延伸超过近端和远端，以便于连接到电极和连接器。

公开(公告)号：US09095700B2

公开(公告)日：2015-08-04

申请号：US13571987

申请日：2012-08-10

Applicant: Lawrence Kane ,  Elliot W. Bridgeman ,  John Swoyer

Inventor： Lawrence Kane ,  Elliot W. Bridgeman ,  John Swoyer

IPC: A61N1/00 ,  A61N1/05 ,  A61F2/90 ,  A61B18/00 ,  A61B18/14

CPC classification number: A61N1/0558 ,  A61B18/1492 ,  A61B2018/00214 ,  A61B2018/00285 ,  A61F2/90 ,  A61N1/057 ,  A61N2001/058

Abstract: A therapy assembly configured for at least partial insertion in a living body. A plurality of fixation structures are disposed radially around the therapy delivery element proximate the electrodes. The fixation structures include wires having a diameter in a range between about 0.004 inches and about 0.020 inches. The wires have a first end attached to the therapy delivery element and a second end attached to a sliding member configured to slide along the therapy delivery element. The fixation structures are configured to collapse inward to a collapsed configuration when inserted into a lumen of an introducer and to deploy to a deployed configuration when the introducer is retracted. A fitting is located at proximal end of the introducer that releasably locks the therapy delivery element to the introducer, such that torque applied to the fitting is substantially transmitted to the distal end of the therapy assembly.

Abstract translation: 一种治疗组件，其构造成用于至少部分地插入生物体内。 多个固定结构被放置在靠近电极的治疗递送元件周围。 固定结构包括直径在约0.004英寸和约0.020英寸之间的直径的导线。 电线具有连接到治疗递送元件的第一端和附接到被配置为沿着治疗递送元件滑动的滑动构件的第二端。 固定结构构造成当插入导引器的内腔中时向内折叠成折叠构型，并且当导入器缩回时部署到展开构型。 导管器的近端处的配件位于可释放地将治疗递送元件锁定到导引器上，使得施加到配件的扭矩基本上传递到治疗组件的远端。

公开(公告)号：US08731686B2

公开(公告)日：2014-05-20

申请号：US12630761

申请日：2009-12-03

Applicant: Courtney Lane ,  Jesse Geroy ,  James C. Makous ,  Todd Whitehurst ,  Matthew Flowers ,  John Michael Barker ,  Terry Ferrell ,  John Swoyer ,  Brett Schleicher ,  Jeff Gagnon ,  Andrew DiGiore ,  Ellis Garai ,  Kristen Jaax ,  Rafael Carbunaru

Inventor： Courtney Lane ,  Jesse Geroy ,  James C. Makous ,  Todd Whitehurst ,  Matthew Flowers ,  John Michael Barker ,  Terry Ferrell ,  John Swoyer ,  Brett Schleicher ,  Jeff Gagnon ,  Andrew DiGiore ,  Ellis Garai ,  Kristen Jaax ,  Rafael Carbunaru

IPC: A61N1/00

CPC classification number: A61B17/0057 ,  A61B90/10 ,  A61B2090/103 ,  A61N1/0534 ,  A61N1/0539

Abstract: A burr hole plug comprises a plug base configured for being mounted around a burr hole. The plug base includes an aperture through which an elongated medical device exiting the burr hole may pass. The burr hole plug further comprises a retainer configured for being mounted within the aperture of the plug base. The retainer further includes first and second slidable clamping mechanisms configured for securing the medical devices therebetween within the aperture of the plug base. A method comprises introducing the medical device through the burr hole, mounting a plug base around the burr hole, such that the medical device extends through the plug base aperture, mounting the retainer within the aperture of the plug base, and sliding the first and second clamping mechanisms secure the medical device therebetween.

Abstract translation: 毛刺孔塞包括构造成围绕钻孔安装的塞子基座。 插头基座包括一个孔，通过该孔可以使离开钻孔的细长医疗装置通过。 毛刺孔塞还包括保持器，其构造成用于安装在插头基座的孔内。 保持器还包括第一和第二可滑动夹紧机构，其被构造用于将医疗装置固定在插头基座的孔内。 一种方法包括：通过毛刺孔引导医疗装置，将插头基座安装在毛刺孔周围，使得医疗装置延伸穿过插头基座孔口，将保持器安装在插头基座的孔内，并将第一和第二 夹紧机构将医疗装置固定在其间。

公开(公告)号：US08676341B2

公开(公告)日：2014-03-18

申请号：US13164942

申请日：2011-06-21

Applicant: Lawrence Kane ,  John Swoyer

Inventor： Lawrence Kane ,  John Swoyer

IPC: A61N1/05

CPC classification number: A61N1/05 ,  A61B17/0401 ,  A61B2017/0084 ,  A61B2017/00858 ,  A61B2017/00964 ,  A61B2017/0417 ,  A61B2017/0475 ,  A61N1/0558 ,  A61N2001/0582

Abstract: Suture anchors for securing therapy delivery elements, such as stimulation leads or catheters, within a living body. The suture anchor includes an inner sleeve constructed with an inner layer of a softer, more pliable material that easily conforms to the therapy delivery element to reduce slippage and an outer layer constructed from a harder, stiffer durometer material that protects the therapy delivery elements from damage due to over-tightening the tie down sutures. A suture material located in the suture groove is tensioned to apply a radial compressive force. The reinforcing structure spreads the radial compressive force along a greater surface area of the therapy delivery element.

Abstract translation: 用于固定活体内的治疗递送元件（例如刺激引线或导管）的缝合锚。 缝合锚包括内套筒，该内套筒具有较软，更柔韧的材料的内层，其容易地符合治疗递送元件以减少滑脱，以及由更硬，更硬的硬度计材料构成的外层，其保护治疗递送元件免受损伤 由于过度紧固缝合缝合。 位于缝合槽中的缝合材料被张紧以施加径向压缩力。 加强结构沿着治疗递送元件的较大表面积扩展径向压缩力。