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公开(公告)号：US09700730B2
公开(公告)日：2017-07-11
申请号：US13099906
申请日：2011-05-03
CPC分类号： A61N1/37229 , A61N1/08 , A61N1/37205 , A61N1/37211 , A61N1/378 , A61N1/3787
摘要： Improved external chargers for charging an implantable medical device, and particularly useful in charging a plurality of such devices, are disclosed. Each of the various embodiments include a plurality of field customization coils for customizing the magnetic charging field generated by the external charger such that the magnetic charging field is not radially symmetric. For example, one embodiment includes a primary coil with a plurality of field customization coils distributed radially with respect to the coil. The generated magnetic charging field can be rendered radially asymmetric by selectively activating or disabling the field customization coils in response to data quantifying the coupling between the various implants and the field customization coils in the charger. If there is a relatively high coupling between a particular implant and a particular customization coil for example, that customization coil can be activated to counter the magnetic charging field at that location, while still maintaining a relatively high magnetic charging field at the location of other implants that may have lower couplings.
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公开(公告)号：US09452288B2
公开(公告)日：2016-09-27
申请号：US11951987
申请日：2007-12-06
CPC分类号： A61N1/37241 , A61B18/12 , A61N1/36017 , A61N1/3625 , A61N1/37 , A61N1/37211 , A61N1/37247 , A61N1/37288 , A61N1/39
摘要： A system for performing a neurostimulation trial comprises an external trial stimulator capable of delivering stimulation energy to a plurality of electrodes carried by one or more stimulation leads. The external trial stimulator is configurable to operate in a plurality of stimulation energy delivery modes to respectively emulate one of different neurostimulator types. The system may further comprise a programmer capable of configuring the external trial stimulator to operate in one of the stimulation energy delivery modes. The programmer may be capable of generating a first programming screen capable of allowing a first set of stimulation parameters to be defined for the first neurostimulator type, and a second programming screen capable of allowing a second set of stimulation parameters to be defined for a second neurostimulator type.
摘要翻译： 用于执行神经刺激试验的系统包括能够将刺激能量递送到由一个或多个刺激引线携带的多个电极的外部刺激器。 外部刺激器可配置为在多个刺激能量递送模式中操作以分别模拟不同神经刺激器类型之一。 该系统还可以包括能够配置外部试用刺激器以在刺激能量递送模式之一中操作的编程器。 程序员可能能够生成第一编程屏幕，其能够允许为第一神经刺激器类型定义第一组刺激参数;以及第二编程屏幕，其能够允许为第二神经刺激器定义第二组刺激参数 类型。
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公开(公告)号：US20100145357A1
公开(公告)日：2010-06-10
申请号：US12630761
申请日：2009-12-03
申请人： Courtney Lane , Jesse Geroy , James C. Makous , Todd Whitehurst , Matthew Flowers , John Michael Barker , Terry Ferrell , John Swoyer , Brett Schleicher , Jeff Gagnon , Andrew Digiore , Ellis Garai , Kristen Jaax , Rafael Carbunaru
发明人： Courtney Lane , Jesse Geroy , James C. Makous , Todd Whitehurst , Matthew Flowers , John Michael Barker , Terry Ferrell , John Swoyer , Brett Schleicher , Jeff Gagnon , Andrew Digiore , Ellis Garai , Kristen Jaax , Rafael Carbunaru
CPC分类号： A61B17/0057 , A61B90/10 , A61B2090/103 , A61N1/0534 , A61N1/0539
摘要： A burr hole plug comprises a plug base configured for being mounted around a burr hole. The plug base includes an aperture through which an elongated medical device exiting the burr hole may pass. The burr hole plug further comprises a retainer configured for being mounted within the aperture of the plug base. The retainer further includes first and second slidable clamping mechanisms configured for securing the medical devices therebetween within the aperture of the plug base. A method comprises introducing the medical device through the burr hole, mounting a plug base around the burr hole, such that the medical device extends through the plug base aperture, mounting the retainer within the aperture of the plug base, and sliding the first and second clamping mechanisms secure the medical device therebetween.
摘要翻译： 毛刺孔塞包括构造成围绕钻孔安装的塞子基座。 插头基座包括一个孔，通过该孔可以使离开钻孔的细长医疗装置通过。 毛刺孔塞还包括保持器，其构造成用于安装在插头基座的孔内。 保持器还包括第一和第二可滑动夹紧机构，其被构造用于将医疗装置固定在插头基座的孔内。 一种方法包括：通过毛刺孔引导医疗装置，将插头基座安装在毛刺孔周围，使得医疗装置延伸穿过插头基座孔口，将保持器安装在插头基座的孔内，并将第一和第二 夹紧机构将医疗装置固定在其间。
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公开(公告)号：US20090149917A1
公开(公告)日：2009-06-11
申请号：US11951987
申请日：2007-12-06
IPC分类号： A61N1/08
CPC分类号： A61N1/37241 , A61B18/12 , A61N1/36017 , A61N1/3625 , A61N1/37 , A61N1/37211 , A61N1/37247 , A61N1/37288 , A61N1/39
摘要： A system for performing a neurostimulation trial comprises an external trial stimulator capable of delivering stimulation energy to a plurality of electrodes carried by one or more stimulation leads. The external trial stimulator is configurable to operate in a plurality of stimulation energy delivery modes to respectively emulate one of different neurostimulator types. The system may further comprise a programmer capable of configuring the external trial stimulator to operate in one of the stimulation energy delivery modes. The programmer may be capable of generating a first programming screen capable of allowing a first set of stimulation parameters to be defined for the first neurostimulator type, and a second programming screen capable of allowing a second set of stimulation parameters to be defined for a second neurostimulator type.
摘要翻译： 用于执行神经刺激试验的系统包括能够将刺激能量递送到由一个或多个刺激引线携带的多个电极的外部刺激器。 外部刺激器可配置为在多个刺激能量递送模式中操作以分别模拟不同神经刺激器类型之一。 该系统还可以包括能够配置外部试用刺激器以在刺激能量递送模式之一中操作的编程器。 程序员可能能够生成第一编程屏幕，其能够允许为第一神经刺激器类型定义第一组刺激参数;以及第二编程屏幕，其能够允许为第二神经刺激器定义第二组刺激参数 类型。
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公开(公告)号：US20090112327A1
公开(公告)日：2009-04-30
申请号：US12258382
申请日：2008-10-24
申请人： Courtney Lane , Jesse Geroy , James C. Makous , Todd Whitehurst , Matthew Flowers , John Michael Barker , Terry Ferrell , John Swoyer , Brett Schleicher , Jeff Gagnon , Andrew Digiore , Ellis Garai , Kristen Jaax , Rafael Carbunaru
发明人： Courtney Lane , Jesse Geroy , James C. Makous , Todd Whitehurst , Matthew Flowers , John Michael Barker , Terry Ferrell , John Swoyer , Brett Schleicher , Jeff Gagnon , Andrew Digiore , Ellis Garai , Kristen Jaax , Rafael Carbunaru
CPC分类号： A61B17/0057 , A61B90/10 , A61B2090/103 , A61N1/0534 , A61N1/0539
摘要： A burr hole plug comprises a plug base including a flange configured for being mounted around a burr hole, an aperture through which an elongated medical device may pass, and tabs configured for extending within the cranial burr hole to center the plug base relative to the cranial burr hole. The burr hole plug further comprises a retainer configured for being mounted within the aperture of the plug base to secure the medical device. A method may comprise locating the plug base within a burr hole, such that the tabs are disposed within the burr hole to center the plug base relative to the cranial burr hole, introducing the elongated medical device through the cranial burr hole and into the brain tissue of the patient, mounting the retainer within the aperture of the plug base, and actuating the retainer to secure the medical device.
摘要翻译： 一个钻孔塞包括一个插头基座，它包括一个凸缘，该凸缘被配置成安装在一个钻孔周围，一个细长的医疗设备可以通过的孔，以及在头部钻孔内延伸的突出部分，以使插头基座相对于头部 钻孔。 毛刺孔塞还包括保持器，其构造成安装在插头基座的孔内以固定医疗装置。 一种方法可以包括将插头基座定位在钻孔内，使得突出部设置在毛刺孔内，以使塞子基座相对于头颅毛孔中心，将细长的医疗装置通过头颅毛孔引入脑组织 将保持器安装在插头基座的孔内，并致动保持器以固定医疗装置。
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公开(公告)号：US20080021503A1
公开(公告)日：2008-01-24
申请号：US11779769
申请日：2007-07-18
申请人： Todd Whitehurst , James Thacker , James McGivern , Kelly McClure
发明人： Todd Whitehurst , James Thacker , James McGivern , Kelly McClure
IPC分类号： A61N1/05
CPC分类号： A61N1/36114 , A61M5/14276 , A61M2205/054 , A61M2205/3523 , A61M2205/8206 , A61M2230/06
摘要： A method for treating a patient may include treating coronary artery disease in combination with angina pectoris and/or the control of angina pain by delivering chemical and/or electrical stimulation pulses to the cardiac and/or nervous tissue of the patient in a coordinated manner. A system for treating a patient suffering from coronary artery disease and angina may include a stimulator that generates at least one pulse in accordance with prescribed parameters, a catheter, a lead, and/or a sensor.
摘要翻译： 用于治疗患者的方法可以包括通过以协调的方式将化学和/或电刺激脉冲递送到患者的心脏和/或神经组织来治疗与心绞痛联合的冠状动脉疾病和/或控制心绞痛。 用于治疗患有冠状动脉疾病和心绞痛的患者的系统可以包括根据规定参数产生至少一个脉冲的刺激器，导管，引线和/或传感器。
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7.发明申请公开(公告)号：US20070066997A1
公开(公告)日：2007-03-22
申请号：US11232540
申请日：2005-09-21
申请人： Tom He , Todd Whitehurst , Alfred Mann , Peter Johnson
发明人： Tom He , Todd Whitehurst , Alfred Mann , Peter Johnson
IPC分类号： A61N1/36
CPC分类号： A61N1/372 , A61N1/37205
摘要： Systems for providing stimulation with an implantable system control unit and for optimally positioning that system control unit include a system control unit configured to provide a stimulus to a patient with a member attached to the system control unit for pulling the system control unit into position within the patient. Methods of optimally positioning the implantable system control unit within a patient such that the system control unit is proximal to target tissue that is to be stimulated by the system control unit include threading a member through a patient's body using a needle, the member passing proximal to the target tissue and being attached to the system control unit, and pulling the system control unit into place with the member.
摘要翻译： 用于用可植入系统控制单元提供刺激并且用于最佳地定位该系统控制单元的系统包括系统控制单元，该系统控制单元被配置为向患者提供具有连接到系统控制单元的构件的刺激，用于将系统控制单元牵引到 患者。 将可植入系统控制单元最佳地定位在患者体内的方法，使得系统控制单元靠近要由系统控制单元刺激的目标组织，包括使用针穿过患者身体的部件， 目标组织并附接到系统控制单元，并且将系统控制单元拉到构件的适当位置。
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8.发明申请公开(公告)号：US20060241717A1
公开(公告)日：2006-10-26
申请号：US10224021
申请日：2002-08-19
申请人： Todd Whitehurst , James McGivern
发明人： Todd Whitehurst , James McGivern
IPC分类号： A61N1/36
CPC分类号： A61N1/36082 , A61N1/37288 , A61N1/3756 , A61N1/3787
摘要： System and methods for introducing one or more stimulating drugs and/or applying electrical stimulation to the cortex of the brain to treat movement disorders uses at least one implantable system control unit (SCU), specifically an implantable signal/pulse generator (IPG) or microstimulator with two or more electrodes in the case of electrical stimulation, and an implantable pump with one or more infusion outlets in the case of drug infusion. In certain embodiments, a single SCU provides both electrical stimulation and one or more stimulating drugs. In some embodiments, one or more sensed conditions are used to adjust stimulation parameters.
摘要翻译： 用于引入一种或多种刺激性药物和/或对大脑皮层施加电刺激以治疗运动障碍的系统和方法使用至少一个可植入系统控制单元（SCU），特别是可植入信号/脉冲发生器（IPG）或微刺激器 在电刺激的情况下具有两个或更多个电极，以及在药物输注的情况下具有一个或多个输注出口的可植入泵。 在某些实施方案中，单个SCU提供电刺激和一种或多种刺激性药物。 在一些实施例中，使用一个或多个感测到的条件来调整刺激参数。
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公开(公告)号：US20060235484A1
公开(公告)日：2006-10-19
申请号：US11259176
申请日：2005-10-25
申请人： Kristen Jaax , Todd Whitehurst
发明人： Kristen Jaax , Todd Whitehurst
IPC分类号： A61N1/34
CPC分类号： A61N1/3787 , A61N1/0534 , A61N1/36071 , A61N1/37211 , A61N2001/0582
摘要： Methods of applying a stimulus to a stimulation site within the neck or head of a patient include implanting a distal portion of one or more leads adjacent to the stimulation site, forming a loop with a proximal portion of the one or more leads, and securing the distal and proximal portions of the one or more leads to one or more securing sites with one or more securing devices. The distal portion of the one or more leads includes a number of electrodes disposed thereon that are configured to deliver the stimulus to the stimulation site. Systems for applying a stimulus to a stimulation site within the neck or head of a patient include one or more leads having a number of electrodes disposed on a distal portion thereof and one or more securing devices configured to secure the one or more leads to one or more securing sites. The distal portion of the one or more leads is implanted adjacent to the stimulation site and the electrodes are configured to deliver the stimulus to the stimulation site. The proximal portion of the one or more leads is formed in a loop.
摘要翻译： 将刺激施加到患者的颈部或头部内的刺激部位的方法包括将邻近刺激部位的一个或多个引线的远端部分植入，形成具有一个或多个引线的近端部分的环， 一个或多个引线的远端和近端部分具有一个或多个固定装置的一个或多个固定位置。 一个或多个引线的远端部分包括布置在其上的多个电极，其被配置为将刺激传递到刺激部位。 将刺激施加到患者的颈部或头部内的刺激部位的系统包括一个或多个引线，其具有设置在其远端部分上的多个电极，以及一个或多个固定装置，其被配置成将一个或多个引线固定到一个或多个引线 更多的安全网站。 一个或多个引线的远端部分被邻近刺激部位植入，并且电极构造成将刺激递送到刺激部位。 一个或多个引线的近端部分形成为环形。
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公开(公告)号：US20060212087A1
公开(公告)日：2006-09-21
申请号：US11081417
申请日：2005-03-15
申请人： Matthew Haller , Jay Daulton , Todd Whitehurst , Rafael Carbunaru
发明人： Matthew Haller , Jay Daulton , Todd Whitehurst , Rafael Carbunaru
IPC分类号： A61N1/36
CPC分类号： A61N1/375 , A61N1/36007 , A61N1/37205
摘要： Exemplary implantable stimulators for stimulating a stimulation site within a patient include an electronic module configured to generate stimulation and a housing configured to house the electronic module. The housing has a shape allowing the a stimulator and a surgical device to be accommodated together within an insertion tool used to insert the stimulator into the patient. Exemplary methods of stimulating a stimulation site within a patient include generating stimulation with an electronic module and housing the electronic module in a housing. The housing has a shape allowing the housing and a surgical device to be accommodated together within an insertion tool used to insert the housing into the patient.
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