利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

53 条记录 (耗时 0.032 秒)

    Method Of Using Barbed Sutures For Gastric Volume Reduction
    32.
    发明申请
    Method Of Using Barbed Sutures For Gastric Volume Reduction 审中-公开
    用于胃体积减少的带刺缝线的方法

    公开(公告)号：US20100174299A1

    公开(公告)日：2010-07-08

    申请号：US12634308

    申请日：2009-12-09

    申请人： Frank Viola ,  Nadya Belcheva

    发明人： Frank Viola ,  Nadya Belcheva

    IPC分类号： A61B17/08 ,  A61B17/04

    CPC分类号： A61F5/0083 ,  A61B2017/00818 ,  A61B2017/0417 ,  A61B2017/06047 ,  A61B2017/06057 ,  A61B2017/0609 ,  A61B2017/06176

    摘要： A method of gastric reduction is disclosed that includes the steps of: inserting an oral-gastric device into the interior volume of the stomach of a subject; and inserting through the esophagus at least one barbed suture in proximity to the muscularis of the stomach of a subject. The barbed suture has a first end having a pointed configuration, and a second end. The muscularis comprise at least first and second surfaces that are in at least partially interfacing relationship to one another in the interior volume. The method also includes inserting the first and/or the second end of the barbed suture through the muscularis to form at least first and second pull regions; and pulling the ends to cause the first pull region to move the first surface towards the interior volume and to cause the second pull region to move the second surface towards the interior volume.

    摘要翻译： 公开了一种胃溃疡的方法，其包括以下步骤：将口胃装置插入到受试者的胃的内部体积中; 并且通过食道插入至少一个有刺的缝合线靠近受试者的胃的肌肉。 有倒勾的缝合线具有尖端构造的第一端和第二端。 肌肉包括至少第一和第二表面，其在内部体积中彼此至少部分相互接触。 所述方法还包括将有倒钩的缝合线的第一和/或第二端插入穿过肌层以形成至少第一和第二拉伸区域; 并且拉动所述端部以使所述第一拉伸区域朝向所述内部空间移动所述第一表面，并且使所述第二拉伸区域朝向所述内部空间移动所述第二表面。

    Functionalized Inclusion Complexes As Crosslinkers
    34.
    发明申请
    Functionalized Inclusion Complexes As Crosslinkers 失效
    功能化包合配合物作为交联剂

    公开(公告)号：US20100010159A1

    公开(公告)日：2010-01-14

    申请号：US12493508

    申请日：2009-06-29

    申请人： Nadya Belcheva

    发明人： Nadya Belcheva

    IPC分类号： C08L5/02 ,  C08G65/00

    CPC分类号： C08L5/16 ,  C08B37/0015

    摘要： The present disclosure relates to crosslinked polymer compositions comprising an inclusion complex functionalized with one or more reactive groups and a polymer functionalized with one or more complimentary reactive groups.

    摘要翻译： 本公开涉及交联聚合物组合物，其包含用一个或多个反应性基团官能化的包合络合物和用一个或多个互补反应性基团官能化的聚合物。

    PURIFICATION OF P-DIOXANONE
    35.
    发明申请
    PURIFICATION OF P-DIOXANONE 失效
    P二氧化硅的纯化

    公开(公告)号：US20100004471A1

    公开(公告)日：2010-01-07

    申请号：US12481287

    申请日：2009-06-09

    申请人： Nadya Belcheva ,  Trang Huynh ,  Darlene Nebinger ,  Ronald Rutka

    发明人： Nadya Belcheva ,  Trang Huynh ,  Darlene Nebinger ,  Ronald Rutka

    IPC分类号： C07D319/12

    CPC分类号： C07D319/12

    摘要： The present disclosure provides methods for purifying p-dioxanone. In embodiments, crude p-dioxanone may be contacted with at least one isocyanate-functionalized scavenger. The at least one isocyanate-functionalized scavenger may react with hydroxyl compounds present with the crude p-dioxanone to form reaction products, in embodiments polyurethanes and/or polyureas, which may then be removed. The p-dioxanone thus obtained is of greater purity than the starting crude p-dioxanone.

    摘要翻译： 本公开提供了对二恶烷酮的纯化方法。 在实施方案中，粗对二氧杂环己酮可以与至少一种异氰酸酯官能化的清除剂接触。 至少一种异氰酸酯官能化的清除剂可与存在于粗对二恶烷酮中的羟基化合物反应以形成反应产物，在实施方案中可以除去聚氨酯和/或聚脲。 由此获得的对二恶烷酮的纯度比起始粗对二恶烷酮的纯度高。

    Method of enhancing the delivery of nucleic acids using silica nanoparticles
    40.
    发明授权
    Method of enhancing the delivery of nucleic acids using silica nanoparticles 失效
    使用二氧化硅纳米粒子增强核酸输送的方法

    公开(公告)号：US06319715B1

    公开(公告)日：2001-11-20

    申请号：US09556074

    申请日：2000-04-21

    申请人： Dan Luo ,  W. Mark Saltzman ,  Ernest Han ,  Nadya Belcheva

    发明人： Dan Luo ,  W. Mark Saltzman ,  Ernest Han ,  Nadya Belcheva

    IPC分类号： C12N1588

    CPC分类号： C12N15/87 ,  Y10S977/906

    摘要： The present invention provides a method for enhancing the delivery of nucleic acid molecules to cells by increasing the concentration of cells at the cell surface. The method comprises the step of premixing of nucleic acid:vector molecules with nanoparticles that are biocompatible, reversibly associate with the nucleic acids and have a sedimentation rate which increases the concentration of the nucleic acids at the cell surface so as to enhance delivery into the cells.

    摘要翻译： 本发明提供了通过增加细胞表面细胞浓度来增强核酸分子向细胞递送的方法。 该方法包括以下步骤：将核酸：载体分子与生物相容的纳米颗粒预混合，与核酸可逆地结合并具有增加核酸在细胞表面的浓度的沉降速率，从而增强向细胞的传递 。