Anti-inflammatory composition containing macrolactin A and a derivative thereof as active ingredients
    31.
    发明授权
    Anti-inflammatory composition containing macrolactin A and a derivative thereof as active ingredients 有权
    含有促乳素A及其衍生物作为活性成分的抗炎组合物

    公开(公告)号:US09089543B2

    公开(公告)日:2015-07-28

    申请号:US13321112

    申请日:2010-05-24

    IPC分类号: A61K31/335 A61K31/365

    CPC分类号: A61K31/335 A61K31/365

    摘要: The present invention relates to an anti-inflammatory use of macrolactin compounds such as macrolactin A, 7-O-malonyl macrolactin A and 7-O-succinyl macrolactin A, which are produced from a novel Bacillus strain of Bacillus polyfermenticus KJS-2 (KCCM10769P). The macrolactin compounds provided by the present invention were confirmed to greatly suppress the expression and formation of inducible nitric oxide synthetase (iNOS) and cyclooxygenase-2 (COX-2) which are proteins related to the formation of inflammatory mediators, and to accordingly inhibit the formation of nitric oxide (NO) and of prostaglandin E2 (PGE2) which are the metabolites of the proteins. In addition, the macrolactin compounds provided by the present invention were confirmed to have excellent effects in inhibiting the formation of tumor necrosis factor-alpha (TNF-α), interleukin-1β (IL-1β), interleukin-6 (IL-6) and granulocyte macrophage colony-stimulating factor (GM-CSF), which are pro-inflammatory cytokines. Therefore, the macrolactin compounds produced by the Bacillus polyfermenticus KJS-2 strain according to the present invention can provide excellent anti-inflammatory agents.

    摘要翻译: 本发明涉及由新生芽孢杆菌(Bacillus polyfermenticus)KJS-2(KCCM10769P)的芽孢杆菌菌株生产的大多数内消旋用途的大多数乳糖素A,7-O-丙二酰基大内酰胺A和7-O-琥珀酰基大内酰胺素A )。 证实本发明提供的大内酰胺化合物能够大大抑制与形成炎症介质相关的蛋白质的诱导型一氧化氮合成酶(iNOS)和环氧合酶-2(COX-2)的表达和形成,并因此抑制 形成一氧化氮(NO)和作为蛋白质代谢物的前列腺素E2(PGE2)。 此外,本发明提供的大多数内消旋化合物被证实在抑制肿瘤坏死因子-α(TNF-α),白细胞介素-1和bgr的形成方面具有优异的效果。 (IL-1和bgr),白介素-6(IL-6)和粒细胞巨噬细胞集落刺激因子(GM-CSF),其是促炎细胞因子。 因此,本发明的由芽孢杆菌属多发性支原体KJS-2株产生的大分子内酯化合物可提供优异的抗炎剂。

    Method and apparatus for reuse of adaptive partial frequency in a cellular mobile communication system
    33.
    发明授权
    Method and apparatus for reuse of adaptive partial frequency in a cellular mobile communication system 有权
    在蜂窝移动通信系统中重用自适应部分频率的方法和装置

    公开(公告)号:US08804550B2

    公开(公告)日:2014-08-12

    申请号:US12992277

    申请日:2009-05-26

    IPC分类号: H04W16/04

    CPC分类号: H04W72/082 H04W72/0473

    摘要: Disclosed is an adaptive partial frequency reuse method and system in a cellular mobile communication system. The adaptive partial frequency method includes the steps of: receiving interference feedback information transmitted from at least one terminal; determining if there is a terminal located in a cell boundary, based on the received interference feedback information; when there is the terminal located in the cell boundary, dividing the frequency band into multiple frequency sub-bands, and allocating different power to the respective multiple frequency sub-bands for each of the at least one base station; and providing data service to the terminal by using the power allocated the respective frequency sub-bands.

    摘要翻译: 公开了一种蜂窝移动通信系统中的自适应部分频率重用方法和系统。 自适应偏频法包括以下步骤:接收从至少一个终端发送的干扰反馈信息; 基于所接收的干扰反馈信息确定是否存在位于小区边界中的终端; 当存在位于小区边界中的终端时,将频带划分成多个频率子带,并且为至少一个基站中的每一个为各个多个频率子带分配不同的功率; 以及通过使用分配各个频率子带的功率向终端提供数据服务。

    Method and apparatus for transmitting/receiving feedback information in mobile telecommunication using multiple input multiple output
    37.
    发明授权
    Method and apparatus for transmitting/receiving feedback information in mobile telecommunication using multiple input multiple output 有权
    用于使用多输入多输出在移动电信中发送/接收反馈信息的方法和装置

    公开(公告)号:US08165075B2

    公开(公告)日:2012-04-24

    申请号:US12013786

    申请日:2008-01-14

    IPC分类号: H04W4/00

    摘要: A method for transmitting feedback information in a mobile communication system using Multiple Input Multiple Output (MIMO) is provided. The method includes, when knockdown precoding is used and Antenna Selection precoding is used, setting an index field for indicating a universal matrix of a precoding matrix of a first reverse feedback channel to a value indicating whether Antenna Selection Space Time Transmit Diversity (STTD) is present; when the knockdown precoding is used and the Antenna Selection precoding is used, writing antenna selection information in a vector bitmap field of the first reverse feedback channel; and when the knockdown precoding is used and the Antenna Selection precoding is used, estimating Channel Quality Information (CQI) according to the antenna selection information and writing the estimated CQI in a CQI field of a second reverse feedback channel.

    摘要翻译: 提供了一种在使用多输入多输出(MIMO)的移动通信系统中发送反馈信息的方法。 该方法包括:当使用击倒预编码并使用天线选择预编码时,将用于指示第一反向反馈信道的预编码矩阵的通用矩阵的索引字段设置为指示天线选择时间发送分集(STTD)是否为 当下; 当使用击倒预编码并使用天线选择预编码时,将天线选择信息写入第一反向反馈信道的矢量位图字段; 并且当使用击倒预编码并且使用天线选择预编码时,根据天线选择信息估计信道质量信息(CQI)并将估计的CQI写入第二反向反馈信道的CQI字段。

    ANTI-INFLAMMATORY COMPOSITION CONTAINING MACROLACTIN A AND A DERIVATIVE THEREOF AS ACTIVE INGREDIENTS
    38.
    发明申请
    ANTI-INFLAMMATORY COMPOSITION CONTAINING MACROLACTIN A AND A DERIVATIVE THEREOF AS ACTIVE INGREDIENTS 有权
    含有MACROLACTIN A及其衍生物作为活性成分的抗炎组合物

    公开(公告)号:US20120071549A1

    公开(公告)日:2012-03-22

    申请号:US13321112

    申请日:2010-05-24

    CPC分类号: A61K31/335 A61K31/365

    摘要: The present invention relates to an anti-inflammatory use of macrolactin compounds such as macrolactin A, 7-O-malonyl macrolactin A and 7-O-succinyl macrolactin A, which are produced from a novel Bacillus strain of Bacillus polyfermenticus KJS-2 (KCCM10769P). The macrolactin compounds provided by the present invention were confirmed to greatly suppress the expression and formation of inducible nitric oxide synthetase (iNOS) and cyclooxygenase-2 (COX-2) which are proteins related to the formation of inflammatory mediators, and to accordingly inhibit the formation of nitric oxide (NO) and of prostaglandin E2 (PGE2) which are the metabolites of the proteins. In addition, the macrolactin compounds provided by the present invention were confirmed to have excellent effects in inhibiting the formation of tumor necrosis factor-alpha (TNF-α), interleukin-1β (IL-1β), interleukin-6 (IL-6) and granulocyte macrophage colony-stimulating factor (GM-CSF), which are pro-inflammatory cytokines. Therefore, the macrolactin compounds produced by the Bacillus polyfermenticus KJS-2 strain according to the present invention can provide excellent anti-inflammatory agents.

    摘要翻译: 本发明涉及由新生芽孢杆菌(Bacillus polyfermenticus)KJS-2(KCCM10769P)的芽孢杆菌菌株生产的大多数内消旋用途的大多数乳糖素A,7-O-丙二酰基大内酰胺素A和7-O-琥珀酰基大内酰胺素A )。 证实本发明提供的大内酰胺化合物能够大大抑制与形成炎症介质相关的蛋白质的诱导型一氧化氮合成酶(iNOS)和环氧合酶-2(COX-2)的表达和形成,并因此抑制 形成一氧化氮(NO)和作为蛋白质代谢物的前列腺素E2(PGE2)。 此外,本发明提供的大多数内消旋化合物被证实在抑制肿瘤坏死因子-α(TNF-α),白细胞介素-1和bgr的形成方面具有优异的效果。 (IL-1和bgr),白介素-6(IL-6)和粒细胞巨噬细胞集落刺激因子(GM-CSF),其是促炎细胞因子。 因此,本发明的由芽孢杆菌属多发性支原体KJS-2株产生的大分子内酯化合物可提供优异的抗炎剂。

    Apparatus and method for efficiently transmitting/receiving a control channel in a mobile communication system simultaneously supporting a synchronous HRPD system and an OFDM system
    40.
    发明授权
    Apparatus and method for efficiently transmitting/receiving a control channel in a mobile communication system simultaneously supporting a synchronous HRPD system and an OFDM system 有权
    在同时支持同步HRPD系统和OFDM系统的移动通信系统中有效地发送/接收控制信道的装置和方法

    公开(公告)号:US08059552B2

    公开(公告)日:2011-11-15

    申请号:US11728372

    申请日:2007-03-26

    IPC分类号: H04L12/26

    摘要: An apparatus and method for efficiently transmitting/receiving a control channel in a mobile communication system simultaneously supporting a synchronous High-Rate Packet Data (HRPD) system and an Orthogonal Frequency Division Multiplexing (OFDM) system. Power of a control channel to be transmitted is measured. The measured power is compared with marginal maximum power set by a higher layer. According to the comparison result, information indicating whether a previous reverse packet has been successfully received and power control information for controlling power of a reverse link is inserted and transmitted in at least one of a Medium Access Control (MAC) channel and an OFDM symbol.

    摘要翻译: 一种用于在同时支持同步高速率分组数据(HRPD)系统和正交频分复用(OFDM))系统的移动通信系统中有效地发送/接收控制信道的装置和方法。 测量要发送的控制信道的功率。 将测量的功率与由较高层设置的边际最大功率进行比较。 根据比较结果,在介质访问控制(MAC)信道和OFDM符号中的至少一个中插入并发送用于指示先前的反向分组是否已经被成功接收的信息和用于控制反向链路的功率的功率控制信息。