公开(公告)号：US07816074B2

公开(公告)日：2010-10-19

申请号：US10566559

申请日：2004-07-30

Applicant: Sheryl Smith ,  Keith Williams

Inventor： Sheryl Smith ,  Keith Williams

IPC: G01N33/53 ,  G01N33/532

CPC classification number: G01N33/9426 ,  A61K49/0004 ,  G01N33/5058 ,  G01N33/948 ,  G01N2800/304 ,  G01N2800/307

Abstract: The present invention is directed to a screening mechanism for identifying members of the general population at increased risk for alcoholism and premenstrual syndrome. The screening mechanisms may be used to measure the expression of the α4β2δ GABAA receptors, in order to identify members of the general population as having an increased sensitivity to lower concentrations alcohol coupled with a decrease sensitivity to higher concentrations of alcohol, a scenario frequently found in patients suffering from alcoholism and premenstrual anxiety. Methods of screening for drugs which decrease expression of the α4β2δ subunit of GABAA are also provided.

Abstract translation: 本发明涉及用于鉴定酗酒和经前期综合征风险增加的一般群体成员的筛选机制。 筛选机制可用于测量α4和bgr;2δGABA A受体的表达，以便将一般群体的成员鉴定为对较低浓度的酒精具有增加的敏感性，同时降低对较高浓度酒精的敏感性，一种情况 发现患有酒精中毒和经前期焦虑的患者。 还提供了降低GABAA的α4和bgr2δ亚基表达的药物筛选方法。

公开(公告)号：US20090287153A1

公开(公告)日：2009-11-19

申请号：US12509063

申请日：2009-07-24

Applicant: Timothy Bresina ,  Steve Cote ,  Mark Faust ,  James Marrs ,  Keith Williams

Inventor： Timothy Bresina ,  Steve Cote ,  Mark Faust ,  James Marrs ,  Keith Williams

IPC: A61M5/158

CPC classification number: A61M5/158 ,  A61M2005/1581 ,  A61M2005/1585 ,  A61M2005/1587

Abstract: A device for inserting a subcutaneous infusion device into skin of a patient. The device can include a housing, a needle hub including a needle, a sleeve, and a spring engaging the needle hub. The device can also include a cap coupled to the housing, and a retention member configured to maintain the device in a ship state prior to decoupling of the cap from the housing. In one example, the retention member can include a boss coupled to the cap and configured to engage the infusion device to maintain the infusion device in the ship state prior to decoupling of the cap from the housing. In another example, the retention member can include a tab formed by the sleeve, the tab engaging a bead on an internal surface of the cap when the sleeve moves relative to the housing while the device is in the ship state.

Abstract translation: 一种用于将皮下输注装置插入患者皮肤的装置。 该装置可以包括壳体，包括针的针座，套筒和与针座接合的弹簧。 该装置还可以包括联接到壳体的盖，以及保持构件，其构造成在将盖与壳体分离之前将装置保持在船状态。 在一个示例中，保持构件可以包括联接到盖并且构造成接合输注装置的凸台，以在将盖与壳体解耦之前将输注装置保持在船状态。 在另一个示例中，保持构件可以包括由套筒形成的突出部，当套管处于船状态时，当套筒相对于壳体移动时，突片接合盖的内表面上的胎圈。

公开(公告)号：US20090024862A1

公开(公告)日：2009-01-22

申请号：US11779432

申请日：2007-07-18

Applicant: Kenneth J. Goodnow ,  Clarence R. Ogilvie ,  Sebastian T. Ventrone ,  Keith Williams ,  Charles S. Woodruff

Inventor： Kenneth J. Goodnow ,  Clarence R. Ogilvie ,  Sebastian T. Ventrone ,  Keith Williams ,  Charles S. Woodruff

IPC: G06F1/30

CPC classification number: G06F1/3203

Abstract: A method and structure to optimize computational efficiency in a low-power environment. The method includes determining an optimal point for maximizing computational efficiency in a low-power environment, and selectively controlling operation of at least one processing unit of a plurality of processing units in accordance with the determined optimal point. The structure includes a plurality of processing units, a load manager controlling selective parallel operation of at least one processing unit of the plurality of processing units, and an unregulated power source.

Abstract translation: 一种在低功耗环境下优化计算效率的方法和结构。 该方法包括确定用于在低功率环境中最大化计算效率的最佳点，以及根据所确定的最佳点选择性地控制多个处理单元中的至少一个处理单元的操作。 该结构包括多个处理单元，控制多个处理单元中的至少一个处理单元的选择性并行操作的负载管理器和未调节的电源。

公开(公告)号：US20070228830A1

公开(公告)日：2007-10-04

申请号：US11278262

申请日：2006-03-31

Applicant: Kerry Bernstein ,  Kenneth Goodnow ,  Clarence Ogilvie ,  Keith Williams ,  Sebastian Ventrone

Inventor： Kerry Bernstein ,  Kenneth Goodnow ,  Clarence Ogilvie ,  Keith Williams ,  Sebastian Ventrone

IPC: H02J3/00

CPC classification number: G06F1/3203 ,  G06F1/3287 ,  H01L25/16 ,  H01L28/60 ,  H01L2224/16225 ,  H01L2924/15311 ,  H01L2924/19041 ,  H01L2924/19105 ,  Y02D10/171 ,  Y10T307/391

Abstract: A method of reducing static power consumption in a low power electronic device. The electronic device including one or more power islands, each power island including: a local storage capacitor coupling a local power grid to a local ground grid; and a functional circuit connected between the local power grid and the local ground grid; a global storage capacitor coupling a global power grid to a global ground grid, each local ground grid connected to the global ground grid; one or more switches, each switch selectively connecting the global power grid to a single and different corresponding local power grid; and a power dispatch unit adapted to open and close the one or more switches.

Abstract translation: 一种降低低功率电子设备中的静态功耗的方法。 所述电子设备包括一个或多个功率岛，每个功率岛包括：将本地电网耦合到本地接地网的局部存储电容器; 以及连接在本地电网与本地接地网之间的功能电路; 将全球电网耦合到全球接地网的全球存储电容器，每个局部地电网连接到全球接地网; 一个或多个开关，每个开关选择性地将全局电网连接到单个和不同的相应的局部电网; 以及适于打开和关闭所述一个或多个开关的电力调度单元。

公开(公告)号：US20070075733A1

公开(公告)日：2007-04-05

申请号：US11162997

申请日：2005-09-30

Applicant: Kenneth Goodnow ,  Clarence Ogilvie ,  Christopher Reynolds ,  Jack Smith ,  Sebastian Ventrone ,  Keith Williams

Inventor： Kenneth Goodnow ,  Clarence Ogilvie ,  Christopher Reynolds ,  Jack Smith ,  Sebastian Ventrone ,  Keith Williams

IPC: H03K19/177

CPC classification number: H03K19/17776 ,  H03K19/17732 ,  H03K19/17756 ,  H03K19/17772

Abstract: A field programmable gate array (FPGA) device including a non-programming-based default power-on electronic configuration. The non-programming-based default power-on electronic configuration defines a default state to initial a first logic function. Upon power-up, the FPGA device would be enabled to enter the default state without having first to be configured via a conventional programming mode, thus saving processing time during power-up. Several embodiments are disclosed, such as a mask via circuit, an asynchronous set/reset circuit, an unbalanced latch circuit and a flush and scan circuit. A related method is also disclosed to reduce the memory size dedicated to the first logic function to facilitate further programming after power-up. In addition to time saving and further programming, the FPGA device can also allow partial or incremental programming to expand the full functionality to match customer's different needs.

Abstract translation: 包括基于非编程的默认开机电子配置的现场可编程门阵列（FPGA）装置。 非基于编程的默认开机电子配置定义了初始化第一逻辑功能的默认状态。 上电时，FPGA器件将能够进入默认状态，而不必首先通过常规编程模式进行配置，从而节省加电时的处理时间。 公开了几个实施例，例如掩模通孔电路，异步设置/复位电路，不平衡锁存电路和齐平扫描电路。 还公开了一种相关方法，以减少专用于第一逻辑功能的存储器大小，以便在上电之后进一步编程。 除了节省时间和进一步的编程之外，FPGA器件还可以允许部分或增量编程扩展完整的功能以满足客户的不同需求。

公开(公告)号：US20060288897A1

公开(公告)日：2006-12-28

申请号：US11145352

申请日：2005-06-03

Applicant: Keith Williams ,  Michael Maston

Inventor： Keith Williams ,  Michael Maston

IPC: F42B12/44

CPC classification number: F42B12/74 ,  F42B12/22 ,  F42B12/56

Abstract: A method and apparatus for incorporating nanophase elemental materials and metastable interstitial composite materials into projectiles, projectile fragments, ordnance casings, warheads and structural components. The projectile, fragments and casings include an elemental material capable of oxidizing. A coating material that is capable of preventing oxidation of the elemental material and an oxidizing agent may be present and be capable of reacting with the elemental material so that a self-propagating high temperature synthesis reaction from a stabilized solid material is yielded for the purpose of rendering terminal effects or thermal impact to a target at impact.

Abstract translation: 将纳米相元素材料和亚稳态间隙复合材料纳入射弹，射弹碎片，弹药壳，弹头和结构部件的方法和装置。 抛射体，碎片和壳体包括能够氧化的元素材料。 可以存在能够防止元素材料和氧化剂氧化的涂层材料，并且能够与元素材料反应，从而产生来自稳定的固体材料的自扩散的高温合成反应，用于 对目标造成影响的终端效应或热影响。

公开(公告)号：US20050235912A1

公开(公告)日：2005-10-27

申请号：US11167830

申请日：2005-06-27

Applicant: Jeffrey Shutic ,  John Carlson ,  Thomas Hollstein ,  Keith Williams ,  Ernest Fena ,  Harry Lader

Inventor： Jeffrey Shutic ,  John Carlson ,  Thomas Hollstein ,  Keith Williams ,  Ernest Fena ,  Harry Lader

IPC: B65G53/38 ,  B05B7/00 ,  B05B7/14 ,  B05B12/08 ,  B05B12/14 ,  B05B15/00 ,  B05B15/12 ,  B05C5/00 ,  B05D1/12

CPC classification number: B05B7/1404 ,  B05B7/144 ,  B05B7/1454 ,  B05B7/1468 ,  B05B7/1472 ,  B05B12/081 ,  B05B14/43 ,  B05B14/435 ,  B05B14/48 ,  B05B15/25 ,  Y02P70/36

Abstract: An apparatus for applying powder coating material onto large objects such as automotive, truck or other vehicle bodies includes a powder spray booth defining a controlled area within which to apply powder coating material onto the vehicle bodies, a powder kitchen located at a remote position from the powder spray booth, and, a number of feed hoppers located proximate the booth which receive powder coating material from the powder kitchen and supply it to automatically or manually manipulated powder spray guns associated with the booth. Oversprayed powder coating material is removed from the booth interior by a powder collection and recovery system which transmits the oversprayed powder back to the powder kitchen for recirculation to the powder spray guns.

公开(公告)号：US06346304B1

公开(公告)日：2002-02-12

申请号：US09202692

申请日：1998-12-21

Applicant: Ronald Fisher ,  Keith Williams

Inventor： Ronald Fisher ,  Keith Williams

IPC: C23C1600

CPC classification number: F16D69/023 ,  C04B35/83 ,  C23C16/045 ,  C23C16/26 ,  C23C16/46 ,  Y10T428/213 ,  Y10T428/24322 ,  Y10T428/249928 ,  Y10T428/249931 ,  Y10T428/249986 ,  Y10T428/24999 ,  Y10T428/30

Abstract: At least one layer of fibers of a material susceptible to heating by electromagnetic radiation is incorporated in a porous structure. The structure is subjected to the radiation to heat up the body which is contacted with hydrocarbon gas to cause the gas to deposit carbon within the porous structure and thereby cause densification.

Abstract translation: 通过电磁辐射加热的材料的至少一层纤维被并入多孔结构中。 该结构经受辐射以加热与烃气体接触的主体，以使气体将碳沉积在多孔结构内，从而导致致密化。

公开(公告)号：US06180223B2

公开(公告)日：2001-01-30

申请号：US09202720

申请日：1998-12-21

Applicant: Ronald Fisher ,  Keith Williams

Inventor： Ronald Fisher ,  Keith Williams

IPC: B32B522

CPC classification number: F16D69/023 ,  C04B35/83 ,  C23C16/045 ,  C23C16/26 ,  C23C16/46 ,  Y10T428/213 ,  Y10T428/24322 ,  Y10T428/249928 ,  Y10T428/249931 ,  Y10T428/249986 ,  Y10T428/24999 ,  Y10T428/30

Abstract: A method for the densification of a porous structure comprises providing the structure with a body of material (13, 14) which includes a susceptor element foil (14) which is more susceptible to heating by electromagnetic radiation than the other material (13) of the body, exposing said porous structure to hydrocarbon gas and simultaneously applying an electromagnetic field to said porous structure whereby said susceptor element (14) at least in part causes heating of the porous structure to a temperature at which the gas infiltrating the porous structure deposits carbon within the porous structure.

Abstract translation: 用于致密化多孔结构的方法包括为所述结构提供材料体（13,14），所述材料体包括感受器元件箔（14），所述感受体元件箔（14）比电磁辐射的其它材料（13）更容易被电磁辐射加热 将所述多孔结构暴露于烃气体并同时向所述多孔结构施加电磁场，由此所述基座元件（14）至少部分地使所述多孔结构的加热导致渗透所述多孔结构的气体沉积碳的温度 多孔结构。

公开(公告)号：US5613197A

公开(公告)日：1997-03-18

申请号：US334491

申请日：1994-11-03

Applicant: Wilbert B. Copeland ,  Erik Soderburg ,  John Dunwoody ,  Robert Brunner ,  Keith Williams

Inventor： Wilbert B. Copeland ,  Erik Soderburg ,  John Dunwoody ,  Robert Brunner ,  Keith Williams

IPC: H03D7/16 ,  H03J5/02 ,  H03L7/185 ,  H04B1/40 ,  H04B7/14

CPC classification number: H03D7/163 ,  H03J5/0281 ,  H03L7/185 ,  H04B1/40

Abstract: Input RF signals to a transponder, such as a communications satellite, are down converted to a lower intermediate frequency (IF) that is common for each different channel. The channel signals are all processed at the common IF, and then up converted to different respective transmission frequencies. This allows for a down conversion/signal processing/up conversion unit design that is the same for each channel (except for frequency and gain values), and facilitates the use of inexpensive available standard components as well as low bandwidth channel filters. An improved phase noise cancellation phase lock loop (PLL) is preferably used to generate tuning signals used in the up and down conversion processes. The PLL includes two loop mixers, with the down and up conversion mixing signals taken respectively from the inputs to the first and second loop mixers. The first and second loop mixers receive mixing signals at frequencies (T-R) and (T-IF-N.multidot.CLK) respectively, where T is the channel's transmission frequency, R is its reception frequency, N is the PLL's .div.N factor, and CLK is a clock frequency; the PLL's voltage controlled oscillator provides the down conversion tuning signal and the input to the first loop mixer at a frequency (R-IF), while a (T-IF) tuning signal for the up converter is taken from a filtered output of the first loop mixer.

Abstract translation: 向诸如通信卫星的应答器输入RF信号被下变频到每个不同信道共同的较低中频（IF）。 通道信号全部在公共IF处理，然后上变频到不同的各自的传输频率。 这允许对于每个通道（频率和增益值除外）相同的下变频/信号处理/上变频单元设计，并且便于使用便宜的可用标准组件以及低带宽通道滤波器。 改进的相位噪声消除锁相环（PLL）优选地用于产生在上下转换过程中使用的调谐信号。 PLL包括两个环路混频器，其中分别从输入到第一和第二回路混频器的下变频和上变频混频信号。 第一和第二回路混频器分别以频率（TR）和（T-IF-NxCLK）接收混频信号，其中T是信道的传输频率，R是其接收频率，N是PLL的DIVIDED N因子，CLK是 时钟频率; PLL的压控振荡器以频率（R-IF）提供下变频调谐信号和第一回路混频器的输入，而用于上转换器的（T-IF）调谐信号从第一 回路混合器。