摘要:
Novel cyclic adenosine monophosphate derivatives represented by the following general formula: ##STR1## wherein A stands for --S-- or --NH-- and n is an integer of from 2 to 12, ARE SUPERIOR TO KNOWN CYCLIC ADENOSIENE DERIVATIVES IN BIOLOGICAL AND PHARMACOLOGICAL ACTIVITIES, ESPECIALLY PDE-inhibiting activity and membrane permeability. Accordingly, these derivatives are very effective for remedying and controlling diseases caused by disorder of the intracellular cyclic adenosine monophosphate level, such as asthma and scabies. These derivaives can readily be synthesized by reacting an 8-halogeno cyclic adenosine monophosphate of the following general formula ##STR2## wherein X is a halogen atom such as bromine, with an alkali metal salt of a linear alkylmercaptan having 3 to 13 carbon atoms in the alkyl group or a linear alkylamine having 3 to 13 carbon atoms in the alkyl group.
摘要:
A high strength galvanized steel sheet having tensile strength of 590MPa or more which is excellent in fatigue property in punching work, and a manufacturing method thereof are provided. The microstructure includes a ferrite phase having an average grain diameter of 15 μm or less and an area fraction of 60% or more and a martensite phase having an area fraction of 5 to 40%, and an amount of one or more kinds of oxide selected from a group consisting of Fe, Si, Mn, Al, P, Nb, and Ti generated on a surface layer portion of the steel sheet within 100 μm in a steel-sheet-side depth direction from a surface of a base steel sheet directly below a galvanized layer is less than 0.060 g/m2 per one-side surface of the steel sheet.
摘要翻译:提供一种拉伸强度为590MPa以上的冲压加工疲劳性优异的高强度镀锌钢板及其制造方法。 微观结构包括平均粒径为15μm以下,面积分率为60%以上的铁素体相,面积分数为5〜40%的马氏体相和选择的一种以上的氧化物的量 从钢基板表面直接在钢板侧深度方向上在钢板表面层上产生的由Fe,Si,Mn,Al,P,Nb,Ti组成的组中, 在镀锌层以下,钢板的单面表面小于0.060g / m 2。
摘要:
When the process plan made for execution is corrected based on the process correction condition, the variation amount in each of processes based on the process correction condition is calculated as the probability distribution using the probability distribution data generated by obtaining the probability distribution from the variation-amount prediction value of each of the processes. Thereby, the influence degree on other processes when the process is corrected can be estimated not simply as the propagation of the variation fixed value but so as to be more suited to the actual circumstances in accordance with the attribute information and the past variation patterns of the process.
摘要:
The information processing apparatus for project management comprises: a function of displaying on a screen a task area 12 where a symbol 123 representing a document relating to a task constituting a project is displayed; and a function of performing document work according to an operation instruction for the symbol 125 representing the document displayed in the task area 12. The task area 12 has a work area 121 which displays a symbol 123 representing the document, and an output area 122. When a symbol 126 representing a document is moved within the output area 122, the output area 122 displays a symbol representing the document in a task area of another associated task constituting the project.
摘要:
Simulation for evaluating approval/rejection of an action plan of the type in which work breakdown struction is changed by influences of external risk factors is achieved. A simulation apparatus includes a plan/risk input portion for accepting input of action plan data and risk scenario data, a plan/risk simulation portion for conducting simulation of an action plan by using the action plan data and the risk scenario data so accepted, and a plan evaluation output portion for evaluating a simulation result. The plan/risk simulation portion simulates occurrence of a risk phenomenon by using the risk scenario data, determines influence information given by the risk phenomenon to the action plan when the risk phenomenon is simulated as occurring and conducts simulation of the action plan by reflecting the influences of the risk scenario on the action plan by using the influence information so determined.
摘要:
To predict a future work status, a variation amount in working efficiency set according to progress of a work regarding the workload and a variation amount in a work resource are considered, and the working efficiency is compensated according compensation of a work resource amount. Data of variation patterns of the working efficiency and the number of workers are previously defined and stored. A variation pattern for each work is selected from the variation pattern data on the basis of a work schedule data stored in the work schedule data storing section. Variation of the workload resource, the workload, and the working efficiency are stored. The prediction result is displayed. Upon excess and lack in the prediction workload over the scheduled workload in a period may be transferred from that period to the next period and from the next to that period, respectively.
摘要:
A project pre-review estimate method capable of estimating influence of alteration in each process of a project on the whole process (project) considering structural alteration and fluctuating values regarding each process and their factors is provided. The project pre-review estimate method is carried out employing a process evaluation procedure which calculates quantitative and structural alteration amounts of the process plan using not only information on constraints (which has been used by conventional techniques) but also scenario information (in which probability of occurrence of a risk (i.e. a factor of alteration to a process) and the content/degree of influence regarding alteration of arbitrary processes caused by the occurrence of the risk are defined in a scenario format) and information for correcting parameters of the scenario by use of qualitative information on the project.
摘要:
In a graph displaying method for displaying as an analysis subject a collection of constituent members each having a plurality of information parameters, each information parameter of each constituent member is assigned to a display attribute of graphic representation, and a value of the information parameter of each constituent member is converted into a value of the assigned display attribute. Next, a display corresponding to the information parameter of each constituent member is provided by using the converted display attribute value. Then, the value of each information parameter indicating affiliation between constituent members is converted into the display attribute value of a display element which couples display elements of the constituent members, and a display corresponding to the affiliation between the constituent members is provided by using the converted display attribute value.
摘要:
The present invention provides a BA-finished stainless steel product having superior antibacterial properties and corrosion resistance and a method for producing the same. Specifically, after a stainless steel product is subjected to BA treatment, the stainless steel product is immersed in a solution containing Ag ions having a concentration of 0.0001 to 1.0 mol/l so that a BA film contains, in area percentage, 0.0002 to 0.05% of Ag particles and Ag compounds, and further, stainless steel product contains 0.001 to 0.10% by weight of Ag and optionally further contains 0.001 to 0.30% by weight of V.
摘要:
Antibacterial fluoroquinoline derivatives and salts thereof of the following formula are stable and have low toxicity and high photostability and low cytotoxicity under light irradiation: ##STR1## wherein R.sub.1 is hydrogen or lower alkyl; R.sub.2 is hydrogen, optionally protected amino, optionally protected aminocarbonyl or optionally protected carboxyl; R.sub.5 is halogen, lower alkyl or optionally protected hydroxyl or is the same as R.sub.2 ; R.sub.6 is lower alkyl; A is CH.sub.2, optionally protected nitrogen or oxygen; and n and m are each an integer of from 0 to 4, provided that n +m is an integer of from 1 to 4.