公开(公告)号：US20210373033A1

公开(公告)日：2021-12-02

申请号：US17169805

申请日：2021-02-08

Applicant: Meso Scale Technologies, LLC.

Inventor： Eli N. Glezer ,  John Kenten ,  Galina Nikolenko

IPC: G01N33/68

Abstract: The present invention relates to methods of diagnosing glomerulonephritis (GN) in a patient, as well as methods of monitoring the progression of GN and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.

公开(公告)号：US20210116452A1

公开(公告)日：2021-04-22

申请号：US16883468

申请日：2020-05-26

Applicant: Meso Scale Technologies, LLC.

Inventor： Anahit Aghvanyan ,  Eli N. Glezer ,  John Kenten ,  Sudeep Kumar ,  Galina Nikolenko ,  Martin Stengelin ,  Srikant Vaithilingam

IPC: G01N33/574

Abstract: The present invention relates to methods of diagnosing lung cancer in a patient, as well as methods of monitoring the progression of lung cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.

公开(公告)号：US20190011441A1

公开(公告)日：2019-01-10

申请号：US16136498

申请日：2018-09-20

Applicant: Meso Scale Technologies, LLC.

Inventor： Eli N. Glezer ,  John Kenten

IPC: G01N33/543 ,  C12Q1/682 ,  C12Q1/6848 ,  C12Q1/6837 ,  C12Q1/6844

Abstract: The present invention is directed to methods for reducing cross-reactivity between species employed in multiplexed immunoassays.

公开(公告)号：US20180348217A1

公开(公告)日：2018-12-06

申请号：US16054332

申请日：2018-08-03

Applicant: Meso Scale Technologies, LLC

Inventor： Eli N. Glezer ,  Mikayla Higgins ,  John Kenten ,  George Sigal

IPC: G01N33/564

CPC classification number: G01N33/564 ,  G01N2800/104 ,  G01N2800/52

Abstract: The present invention relates to methods of diagnosing lupus in a patient, as well as methods of monitoring the progression of lupus and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.

公开(公告)号：US20180156824A1

公开(公告)日：2018-06-07

申请号：US15847111

申请日：2017-12-19

Applicant: Meso Scale Technologies, LLC.

Inventor： Eli N. Glezer ,  John Kenten ,  Sudeep Kumar ,  Galina Nikolenko

IPC: G01N33/68

CPC classification number: G01N33/6893 ,  G01N2333/4706 ,  G01N2333/4727 ,  G01N2333/70578 ,  G01N2333/70596 ,  G01N2333/8146 ,  G01N2800/347 ,  G01N2800/52

Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.

公开(公告)号：US20150038365A1

公开(公告)日：2015-02-05

申请号：US14447691

申请日：2014-07-31

Applicant: Meso Scale Technologies, LLC

Inventor： Anahit Aghvanyan ,  Eli N. Glezer ,  John Kenten ,  Sudeep Kumar ,  Galina Nikolenko ,  Martin Stengelin ,  Srikant Vaithilingam

IPC: G01N33/574 ,  G01N33/50

CPC classification number: G01N33/57423 ,  G01N2800/52

Abstract: The present invention relates to methods of diagnosing lung cancer in a patient, as well as methods of monitoring the progression of lung cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.

Abstract translation: 本发明涉及诊断患者肺癌的方法，以及监测肺癌进展的方法和/或监测治疗剂或治疗方案的治疗方案的方法。 本发明还涉及结合本文所述的诊断方法使用的测定方法。

公开(公告)号：US20150025004A1

公开(公告)日：2015-01-22

申请号：US14190237

申请日：2014-02-26

Applicant: Meso Scale Technologies, LLC

Inventor： Eli N. Glezer ,  John Kenten ,  Sudeep Kumar ,  Galina Nikolenko

IPC: G01N33/68

CPC classification number: G01N33/6893 ,  G01N2333/4706 ,  G01N2333/4727 ,  G01N2333/70578 ,  G01N2333/70596 ,  G01N2333/8146 ,  G01N2800/347 ,  G01N2800/52

Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.

Abstract translation: 本发明涉及诊断患者肾脏疾病的方法，以及监测肾脏疾病进展的方法和/或监测治疗剂或治疗方案的治疗方案的方法。 本发明还涉及结合本文所述的诊断方法使用的测定方法。

公开(公告)号：US20140274775A1

公开(公告)日：2014-09-18

申请号：US14208040

申请日：2014-03-13

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： Eli N. Glezer ,  John Kenten

IPC: G01N33/543

CPC classification number: G01N33/54306 ,  C12Q1/682 ,  C12Q1/6837 ,  C12Q1/6844 ,  C12Q1/6848 ,  C12Q2531/125 ,  C12Q2533/107 ,  C12Q2565/549

Abstract: The present invention is directed to methods for reducing cross-reactivity between species employed in multiplexed immunoassays.

Abstract translation: 本发明涉及降低多重免疫测定中使用的物种之间的交叉反应性的方法。

公开(公告)号：US20140272939A1

公开(公告)日：2014-09-18

申请号：US14206284

申请日：2014-03-12

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： Anahit Aghvanyan ,  Eli N. Glezer ,  John Kenten ,  George Sigal ,  Martin Stengelin

IPC: G01N33/53 ,  G01N33/569

CPC classification number: G01N33/54393 ,  C12Q1/6804 ,  G01N21/66 ,  G01N21/76 ,  G01N21/77 ,  G01N33/5306 ,  G01N33/5308 ,  G01N33/533 ,  G01N33/54306 ,  G01N33/56988 ,  G01N33/582 ,  G01N2021/7786 ,  C12Q2537/125 ,  C12Q2563/179

Abstract: The present invention is directed to methods for improving assay specificity and performance in binding assays.

Abstract translation: 本发明涉及用于改善结合测定中测定特异性和性能的方法。

公开(公告)号：US20140220007A1

公开(公告)日：2014-08-07

申请号：US14169289

申请日：2014-01-31

Applicant: MESO SCALE TECHNOLOGIES, LLC

Inventor： Eli N. Glezer ,  Mikayla Higgins ,  John Kenten ,  George Sigal

IPC: G01N33/564

CPC classification number: G01N33/564 ,  G01N2800/104 ,  G01N2800/52

Abstract: The present invention relates to methods of diagnosing lupus in a patient, as well as methods of monitoring the progression of lupus and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.

Abstract translation: 本发明涉及诊断患者狼疮的方法，以及监测狼疮进展的方法和/或监测治疗剂或治疗方案治疗方案的方法。 本发明还涉及结合本文所述的诊断方法使用的测定方法。